Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
two-component system
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| D10V | - | - | - | polymyxin b|colistin | Reslit | Candidate |
| S14A | - | - | - | polymyxin b|colistin | Reslit | Candidate |
| T187F | - | - | - | polymyxin b|colistin | Reslit | Candidate |
| L272F | - | - | - | polymyxin b|colistin | Reslit | Candidate |
| Q240E | - | - | - | polymyxin b|colistin | Reslit | Candidate |
| G414R | - | - | - | polymyxin b|colistin | Reslit | Candidate |
| R263C | - | - | - | polymyxin b|colistin | Reslit | Candidate |
| A247T | - | - | Pseudomonas aeruginosa | polymyxin b | Reslit | Candidate |
| Y345H | - | - | Pseudomonas aeruginosa | polymyxin b | Reslit | Candidate |
| L18P | - | - | Pseudomonas aeruginosa | colistin | Reslit | Candidate |
Genomic Analysis of Carbapenem-Resistant Acinetobacter baumannii Isolates Belonging to Major Endemic Clones in South America.
Alterations in two-component regulatory systems of phoPQ and pmrAB are associated with polymyxin B resistance in clinical isolates of Pseudomonas aeruginosa.
Using experimental evolution to identify druggable targets that could inhibit the evolution of antimicrobial resistance.
Mutations in pmrAB are associated with colistin resistance.