pmrf2

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undecaprenyl-phosphate glycosyltransferase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to pmrf2

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Validation StatusCandidate

Overview

Validation Method: heterologous expression and biochemical characterization
Drug Classes: polymyxins
Organisms: Escherichia coli
Geographic Location: sediment|seawater
Papers: 1
Databases: Reslit

Papers1

Discovery and Characterization of Polymyxin-Resistance Genes pmrE and pmrF from Sediment and Seawater Microbiome.

PMID 36602384 · 2023

The study identifies and characterizes novel polymyxin-resistance genes pmrE2, pmrE3, pmrE4, and pmrF2 from sediment and seawater microbiomes. These genes encode enzymes involved in lipid A modification, contributing to polymyxin resistance through biochemical activities.

Gene Information

Gene Name: pmrf2
Allele: pmrF2
Encodes: undecaprenyl-phosphate glycosyltransferase
Source Database: Reslit
Confers Resistance To: polymyxins
Organisms Tested In: • Escherichia coli
Geographic Location: sediment|seawater
Validation Method: heterologous expression and biochemical characterization

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pmrf2

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pmrf2

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