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Explore antimicrobial resistance genes from the literature

ponA2

PBP1b

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to ponA2

Browse AMR rules for ponA2

Overview

Drug Classes: amoxicillin|meropenem
Organisms: Mycobacterium tuberculosis
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
T188A	-	-	Mycobacterium tuberculosis	amoxicillin\|meropenem	Reslit	Candidate

Papers1

1

Uncovering Beta-Lactam Susceptibility Patterns in Clinical Isolates of Mycobacterium tuberculosis through Whole-Genome Sequencing.

PMID 35695524 · 2022

mutations in ponA2 were associated with lower beta-lactam MICs

Mutation Information

Protein Change: T188A
Organisms: Mycobacterium tuberculosis
Confers Resistance To: amoxicillin|meropenem
Source Database: Reslit