Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
outer membrane porin
Overview
Multiple Genetic Analysis System-Based Antibiotic Susceptibility Testing in Helicobacter pylori and High Eradication Rate With Phenotypic Resistance-Guided Quadruple Therapy.
Antibiotic resistance in Helicobacter pylori: From potential biomolecular mechanisms to clinical practice.
The paper discusses the mechanisms of antibiotic resistance in Helicobacter pylori, focusing on genes and mutations associated with resistance to amoxicillin, clarithromycin, furazolidone, levofloxacin, and metronidazole. Key findings include the identification of specific mutations in 23S rRNA, gyrA, gyrB, PBP1A, porD, oorD, RdxA, and other genes that contribute to resistance against these antibiotics.
Helicobacter pylori resistance in Hainan Province, China: investigating phenotypes and genotypes through whole-genome sequencing.
The study identified several AMR genes and mutations in H. pylori strains from Hainan Province, China, including 23S rRNA (A2143G) for clarithromycin resistance, gyrA (N87K, D91N) for levofloxacin resistance, rdxA (R16H/C, M21A) for metronidazole resistance, pbp1A (Thr593Ala, Thr556Ser, Asn562Tyr, Phe366Leu, Val374Leu, Ser414Arg) for amoxicillin resistance, 16S rRNA (AGA926_928>GGA, AGA926_928>AGC, AGA926_928>GGC, AGA926_928>TGA) for tetracycline resistance, porD (A356G, C357T, G353A) and oorD (A41G, A122G, A335G, C349A, C349G) for furazolidone resistance.
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