poxtA-Ef

ABC-F type ribosomal protection protein PoxtA-Ef

Validation StatusConfirmed2+ DBs

Overview

Mechanism: Target protection
Drug Classes: LINEZOLID, CHLORAMPHENICOL, FLORFENICOL, TETRACYCLINE, DOXYCYCLINE
Organisms: Enterococcus faecium
Alleles: 2
Papers: 1
Databases: Reference Gene CatalogResFinder Database

Allele Variants2

Allele	Database	Papers	Drug Classes	Organisms	Countries	Years	Sequence Accession	Protein Accession
PoxtA-Ef	Reference Gene Catalog	1	LINEZOLID, CHLORAMPHENICOL +1	Enterococcus faecium	-	-	NMZI01000003.1	OZN12776.1
poxtA-Ef	ResFinder Database	1	TETRACYCLINE, DOXYCYCLINE +3	-	-	2022	WP094899500.1	-

Papers1

Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.

Gene Name: poxtA-Ef
Allele: poxtA-Ef
Source Database: ResFinder Database
Mechanism: Target protection
Confers Resistance To: TETRACYCLINEDOXYCYCLINELINEZOLIDCHLORAMPHENICOLFLORFENICOL
Sequence Accession: WP094899500.1
Notes: If alone, poxtA confers reduced susceptibility and not resistance to the antimicrobials listed. Also reduced susceptibility to tigecycline in E. coli

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Allele

Database

Papers

Drug Classes

Organisms

Countries

Years

Sequence Accession

Protein Accession

PoxtA-Ef

Reference Gene Catalog

LINEZOLID, CHLORAMPHENICOL +1

Enterococcus faecium

poxtA-Ef

ResFinder Database

TETRACYCLINE, DOXYCYCLINE +3

2022

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