prmB

View on PubMed

SAM-dependent methyltransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to prmB

AMR Rules

Browse AMR rules for prmB

Validation StatusCandidate

Overview

Validation Method: insertional inactivation and sensitivity testing
Drug Classes: tiamulin, clindamycin
Organisms: Azospirillum brasilense Sp7, Escherichia coli
Papers: 1
Databases: Reslit

Papers1

A SAM-dependent methyltransferase cotranscribed with arsenate reductase alters resistance to peptidyl transferase center-binding antibiotics in Azospirillum brasilense Sp7.

PMID 24573606 · 2014

The study identified that the PrmB-type methyltransferase in Azospirillum brasilense is involved in conferring resistance to tiamulin and clindamycin, while causing sensitivity to chloramphenicol.

Gene Information

Gene Name: prmB
Allele: prmB
Encodes: SAM-dependent methyltransferase
Source Database: Reslit
Confers Resistance To: tiamulinclindamycin
Organisms Tested In: • Azospirillum brasilense Sp7
• Escherichia coli
Validation Method: insertional inactivation and sensitivity testing

Comments (0)

No comments yet. Be the first to comment!

prmB

Gene Information

Browse AMR Genes

prmB

Gene Information