Browse AMR Genes

Explore antimicrobial resistance genes from the literature

proY

Cryptic proline/histidine transporter

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to proY

Browse AMR rules for proY

Overview

Drug Classes: enrofloxacin
Organisms: E. coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A235S	-	-	E. coli	enrofloxacin	Reslit	Candidate

Papers1

1

Effects of a previously selected antibiotic resistance on mutations acquired during development of a second resistance in Escherichia coli.

PMID 30975082 · 2019

Mutation in proY was observed in wild-type E. coli adapted to enrofloxacin.

Mutation Information

Protein Change: A235S
Organisms: E. coli
Confers Resistance To: enrofloxacin
Validation Method: Whole genome sequencing and MIC measurements
Source Database: Reslit