Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Ribose-phosphate pyrophosphokinase
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| P314L | - | - | Staphylococcus aureus | vancomycin|daptomycin | Reslit | Candidate |
| A154E | - | - | Staphylococcus aureus | oxacillin | Reslit | Candidate |
| A304V | - | - | Staphylococcus aureus | oxacillin | Reslit | Candidate |
| R132C | - | - | Staphylococcus aureus | oxacillin | Reslit | Candidate |
| D44E | - | - | Staphylococcus aureus | oxacillin | Reslit | Candidate |
| A89T | - | - | Staphylococcus aureus | oxacillin | Reslit | Candidate |
| R79H | - | Escherichia coli | ampicillin | Reslit | Candidate | |
| C60Y | - | Escherichia coli | ampicillin | Reslit | Candidate |
Genetic Determinants of High-Level Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus.
The study identified six genes (fruB, gmk, hpt, purB, prsA, and relA) that are mutated in highly oxacillin-resistant strains of MRSA, highlighting the role of guanine metabolism in determining antibiotic resistance.
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