pstS

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Phosphate ABC transporter

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UniProt

Protein entries specific to pstS

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Validation StatusCandidate

Overview

Mechanism: Frameshift mutation leading to loss of function
Validation Method: Whole-genome resequencing and mutant construction
Drug Classes: polymyxin b
Organisms: Streptococcus pyogenes
Papers: 1
Databases: Reslit

Papers1

Streptococcus pyogenes polymyxin B-resistant mutants display enhanced ExPortal integrity.

PMID 24794568 · 2014

The study identifies pstS mutations as a key factor in polymyxin B resistance in Streptococcus pyogenes, with these mutations enhancing ExPortal integrity.

Gene Information

Gene Name: pstS
Allele: pstS
Encodes: Phosphate ABC transporter
Source Database: Reslit
Mechanism: Frameshift mutation leading to loss of function
Confers Resistance To: polymyxin b
Organisms Tested In: • Streptococcus pyogenes
Validation Method: Whole-genome resequencing and mutant construction

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pstS

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pstS

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