Browse AMR Genes

Explore antimicrobial resistance genes from the literature

pth

peptidyl-tRNA hydrolase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to pth

Browse AMR rules for pth

Overview

Drug Classes: ampicillin
Organisms: Escherichia coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
P101L	C304T	-	Escherichia coli	ampicillin	Reslit	Candidate

Papers1

1

Extreme Antibiotic Persistence via Heterogeneity-Generating Mutations Targeting Translation.

PMID 31964772 · 2020

Mutation Information

pth: p.P101L / c.C304T

Protein Change: P101L
Nucleotide Change: C304T
Organisms: Escherichia coli
Confers Resistance To: ampicillin
Validation Method: transcriptional profiling and persistence assays
Source Database: Reslit