Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Tyrosine-protein kinase, autophosphorylates
Overview
Evolution of Acinetobacter baumannii In Vivo: International Clone II, More Resistance to Ceftazidime, Mutation in ptk.
The study identifies ptk mutations leading to increased resistance to ceftazidime, azithromycin, and sulfonamides in Acinetobacter baumannii, along with adeRS mutations contributing to tigecycline resistance.
Interactions between host epithelial cells and Acinetobacter baumannii promote the emergence of highly antibiotic resistant and highly mucoid strains.
The study identifies mutations in rsmG, rnaseI, and ptk that contribute to antibiotic resistance and mucoid phenotype in Acinetobacter baumannii. These mutations enhance resistance to various antibiotics, including cephalosporins, and alter bacterial behavior by reducing adhesion and internalization.
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