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puuA

Gamma-glutamylputrescine synthetase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to puuA

Browse AMR rules for puuA

Overview

Drug Classes: ciprofloxacin
Organisms: Pseudomonas aeruginosa
Papers: 1
Mutations: 4

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
M419L	-	-	Pseudomonas aeruginosa	ciprofloxacin	Reslit	Candidate
E415D	-	-	Pseudomonas aeruginosa	ciprofloxacin	Reslit	Candidate
M398L	-	-	Pseudomonas aeruginosa	ciprofloxacin	Reslit	Candidate
-	G1236A	-	Pseudomonas aeruginosa	ciprofloxacin	Reslit	Candidate

Papers1

1

Real-time monitoring of Pseudomonas aeruginosa biofilm growth dynamics and persister cells' eradication.

PMID 34663186 · 2021

Mutations in puuA gene detected in colonies grown with CIP.

Mutation Information

puuA: p.M419L puuA: p.E415D puuA: p.M398L puuA: c.G1236A

Protein Change: M419L, E415D, M398L
Nucleotide Change: G1236A
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ciprofloxacin
Validation Method: genome sequencing
Source Database: Reslit