Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
pyruvate kinase
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| G126R | - | decreased its activity | Enterococcus faecium | fosfomycin | Reslit | Candidate |
| T407A | - | Streptococcus pneumoniae | fosfomycin | Reslit | Candidate | |
| D393Y | - | Streptococcus pneumoniae | fosfomycin | Reslit | Candidate | |
| A218V | - | Streptococcus pneumoniae | fosfomycin | Reslit | Candidate | |
| V404E | - | Streptococcus pneumoniae | fosfomycin | Reslit | Candidate |
Evolution of Enterococcus faecium in Response to a Combination of Daptomycin and Fosfomycin Reveals Distinct and Diverse Adaptive Strategies.
Functional and structural characterization of Streptococcus pneumoniae pyruvate kinase involved in fosfomycin resistance.
Pyruvate kinase mutations in S. pneumoniae confer fosfomycin resistance.