Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
quaternary ammonium compound efflux pump
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| qac | Reslit | 8 | quaternary ammonium compounds, chlorhexidine | Salmonella enterica serovar Choleraesuis +7 | Europe, Shanghai, Canada, Global, Denmark, Virginia|Illinois, Türkiye|Xinjiang Province, northwest China, Europe|United States | 2005, 2013, 2017, 2023, 2024, 2025 | NC_003143|NC_004061|NC_002528|NC_004741|NC_004631|NC_004545|NC_000913|NC_004431|NC_004088|NC_003198|NC_002695|NC_002655|NC_004344|NC_004337|NC_003197 | - |
| Qac | Reslit | 1 | quaternary ammonium compounds | Alphaproteobacteria +1 | Atlantic Southwest Shelves Province|Antarctic Province|Indian South Subtropical Gyre | 2020 | - | - |
The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen.
The study identifies multiple antimicrobial resistance genes on plasmids pSC138 and pSCV50 in Salmonella enterica serovar Choleraesuis SC-B67, including blaTEM-1, blaCMY-2, tetRA, strA, aadA2, sulI, sulII, catI, cmlA, aph, sat, mef, mer, ebr, qac, and blaTEM-67. Additionally, mutations in the chromosomal genes gyrA and parC, along with the inactivation of acrR, contribute to ciprofloxacin resistance.
Characteristics of antibiotic resistance of airborne Staphylococcus isolated from metro stations.
The study identified the presence of antibiotic resistance genes mecA and qac in airborne Staphylococcus isolates from metro stations, indicating a higher level of resistance compared to park samples.
Novel Multiplex PCR Assay for Detection of Chlorhexidine-Quaternary Ammonium, Mupirocin, and Methicillin Resistance Genes, with Simultaneous Discrimination of Staphylococcus aureus from Coagulase-Negative Staphylococci.
The study developed a multiplex PCR assay to detect genes associated with resistance to chlorhexidine, quaternary ammonium compounds, mupirocin, and methicillin, while also distinguishing Staphylococcus aureus from coagulase-negative staphylococci.
Global ocean resistome revealed: Exploring antibiotic resistance gene abundance and distribution in TARA Oceans samples.
The study identified 313 ARGs in the global ocean, including mcr-1, which confers resistance to colistin. The most frequent ARGs were Qac and TETB(60), associated with multidrug efflux pumps and tetracycline resistance, respectively.
Systematic In Silico Assessment of Antimicrobial Resistance Dissemination across the Global Plasmidome.
The study identifies various antimicrobial resistance genes (ARGs) and their dissemination patterns across the global plasmidome using %GC content analysis. Key findings include the identification of genes such as sul, dfrA, qnr, CTX-M, OXA, APH(3'), ANT(3''), AAC(6'), mcr, erm, tet, and qac, which are associated with resistance to sulfonamides, trimethoprim, quinolones, beta-lactams, aminoglycosides, polymyxins, macrolides, lincosamides, streptogramins, tetracyclines, and quaternary ammonium compounds.
Co-localization of antibiotic resistance genes is widespread in the infant gut microbiome and associates with an immature gut microbial composition.
The study identifies widespread co-localization of antibiotic resistance genes (ARGs) with other resistance and virulence genes in the infant gut microbiome, highlighting the association with an immature gut microbial composition. Key findings include the frequent co-localization of tetracycline and fluoroquinolone resistance genes, as well as the presence of class 1 integrons on plasmids.
Selection and horizontal gene transfer underlie microdiversity-level heterogeneity in resistance gene fate during wastewater treatment.
The study identifies several resistance genes, including mphA, msrE, tet(39), sul1, sul2, mer, qac, and aadA, which were found to be associated with hospital sewage and showed variations in their persistence in activated sludge. These genes contribute to resistance against macrolides, tetracyclines, sulfonamides, mercury, quaternary ammonium compounds, and aminoglycosides.
Investigation of Various Toxigenic Genes and Antibiotic and Disinfectant Resistance Profiles of Staphylococcus aureus Originating from Raw Milk.
The study identified a high prevalence of antimicrobial resistance genes in Staphylococcus aureus strains isolated from raw milk, including blaI, blaZ, tcaR, IS256, mecA, aac/aph, ant, vanA, dfrA, ermT, tetK, qacC, qacJ, and smr. These genes were associated with resistance to various antibiotics and disinfectants.
Establishing Clinical and Laboratory Standards Institute M45 antimicrobial susceptibility testing methods and breakpoints for Pseudomonas other than Pseudomonas aeruginosa.
The study established tentative CLSI M45 antimicrobial susceptibility testing breakpoints for Pseudomonas other than Pseudomonas aeruginosa (POPA). It identified various beta-lactamase genes, including metallo-beta-lactamases (MBLs) such as bla POM-1, bla POM-2, bla PAM-1, bla PST-1, bla VIM-2, bla CARB-2, bla DHA-1, and bla IMP-13, which confer resistance to carbapenems. Additionally, multidrug-resistant efflux pumps like ttgABC and tmexCD-toprJ were found to contribute to carbapenem resistance. Other resistance genes for aminoglycosides, trimethoprim-sulfamethoxazole, quaternary ammonium compounds, chloramphenicol, and fluoroquinolones were also detected.
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