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recJ

DNA repair protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to recJ

Browse AMR rules for recJ

Overview

Drug Classes: daptomycin
Organisms: Enterococcus faecium
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
Y434C	A1301G	-	Enterococcus faecium	daptomycin	Reslit	Candidate

Papers1

1

Emergence of a daptomycin-non-susceptible Enterococcus faecium strain that encodes mutations in DNA repair genes after high-dose daptomycin therapy.

PMID 27036708 · 2016

Mutation Information

recJ: p.Y434C / c.A1301G

Protein Change: Y434C
Nucleotide Change: A1301G
Organisms: Enterococcus faecium
Confers Resistance To: daptomycin
Validation Method: whole-genome sequencing
Source Database: Reslit