Browse AMR Genes

Explore antimicrobial resistance genes from the literature

rfaC

lipopolysaccharide biosynthesis protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to rfaC

Browse AMR rules for rfaC

Overview

Drug Classes: tigecycline
Organisms: Escherichia coli
Papers: 1
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A42T	-	-	Escherichia coli	tigecycline	Reslit	Candidate
E85K	-	-	Escherichia coli	tigecycline	Reslit	Candidate

Papers1

1

Predicting tigecycline susceptibility in multidrug-resistant Klebsiella species and Escherichia coli strains of environmental origin.

PMID 37328679 · 2023

Mutation Information

rfaC: p.A42T rfaC: p.E85K

Protein Change: A42T, E85K
Organisms: Escherichia coli
Confers Resistance To: tigecycline
Validation Method: whole-genome sequencing and susceptibility testing
Source Database: Reslit