rimI

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alanine acetyltransferase

NCBI Pathogen Isolates

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UniProt

Protein entries specific to rimI

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Validation StatusCandidate

Overview

Mechanism: insertion mutation
Validation Method: whole genome sequencing and RT-qPCR
Drug Classes: fluoroquinolones
Organisms: Staphylococcus aureus
Papers: 1
Databases: Reslit

Papers1

Genomic alterations involved in fluoroquinolone resistance development in Staphylococcus aureus.

PMID 37494330 · 2023

The study identifies mutations in grlA (S80F) and gyrB (T451S and/or R450S) as key contributors to fluoroquinolone resistance in Staphylococcus aureus, along with overexpression of rimI and fmtB.

Gene Information

Gene Name: rimI
Allele: rimI
Encodes: alanine acetyltransferase
Source Database: Reslit
Mechanism: insertion mutation
Confers Resistance To: fluoroquinolones
Organisms Tested In: • Staphylococcus aureus
Validation Method: whole genome sequencing and RT-qPCR
Sequence Accession: GCF_001879295.1

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rimI

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rimI

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