Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
RmtA family 16S rRNA (guanine(1405)-N(7))-methyltransferase
Overview
Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosa.
Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosa.
Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosa.
Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosa.
Genetic environments of the rmtA gene in Pseudomonas aeruginosa clinical isolates.
The study identifies the rmtA gene, a novel 16S rRNA methylase gene, which confers high-level resistance to various aminoglycosides in Pseudomonas aeruginosa clinical isolates.
Global spread of multiple aminoglycoside resistance genes.
The study identifies the global spread of 16S rRNA methylase genes rmtA, rmtB, and armA in gram-negative bacilli, highlighting their role in aminoglycoside resistance.
The aminoglycoside resistance methyltransferases from the ArmA/Rmt family operate late in the 30S ribosomal biogenesis pathway.
The study identifies ArmA and RmtA as aminoglycoside resistance methyltransferases that methylate G1405 in the 16S rRNA of the 30S ribosomal subunit, conferring resistance to aminoglycosides.
Aminoglycoside Resistance: The Emergence of Acquired 16S Ribosomal RNA Methyltransferases.
The paper discusses the emergence and characteristics of acquired 16S ribosomal RNA methyltransferases (16S-RMTases) that confer resistance to aminoglycosides, particularly in gram-negative bacteria. It highlights the importance of these genes in multidrug-resistant organisms and their association with other resistance mechanisms such as carbapenemases.
Occurrence of Acquired 16S rRNA Methyltransferase-Mediated Aminoglycoside Resistance in Clinical Isolates of Enterobacteriaceae within a Tertiary Referral Hospital of Northeast India.
The study identified several 16S rRNA methyltransferase genes (armA, rmtA, rmtB, rmtC, rmtD) responsible for aminoglycoside resistance in Enterobacteriaceae isolates, highlighting their prevalence and association with multidrug resistance.
Isolation, Antimicrobial Resistance Phenotypes, and Virulence Genes of Bordetella bronchiseptica From Pigs in China, 2018-2020.
The study identified several antimicrobial resistance genes in Bordetella bronchiseptica isolates from pigs in China, including aac(3)-IV, aac6'-Ib, rmtA, blaTEM, blaSHV, oqxB, and tetA. These genes confer resistance to various antibiotics such as aminoglycosides, beta-lactams, fluoroquinolones, and tetracyclines.
Effects of Scutellaria baicalensis, Folium Artemisiae argyi, and Galla Chinensis on the protein expression and resistance genes of Exiguobacterium sp. in response to gentamicin.
The study found that Scutellaria baicalensis, Folium Artemisiae argyi, and Galla Chinensis significantly reduced the abundance of gentamicin resistance genes (armA, rmtB, rmtA, rmtC, rmtD) in Exiguobacterium sp.
Biological cost of aminoglycoside resistance Arm/Kam 16S rRNA methyltransferases from natural antibiotic producers and clinical pathogens.
The study characterizes the biological cost of 16S rRNA methyltransferases (ArmA, RmtA, RmtB, RmtC, RmtD, Sgm, KamB, and NpmA) in Escherichia coli, demonstrating their role in conferring high-level aminoglycoside resistance and their impact on bacterial fitness, translational fidelity, and stress response.
Biological cost of aminoglycoside resistance Arm/Kam 16S rRNA methyltransferases from natural antibiotic producers and clinical pathogens.
The study characterizes the biological cost of 16S rRNA methyltransferases (ArmA, RmtA, RmtB, RmtC, RmtD, Sgm, KamB, and NpmA) in Escherichia coli, demonstrating their role in conferring high-level aminoglycoside resistance and their impact on bacterial fitness, translational fidelity, and stress response.
No comments yet. Be the first to comment!