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rpoH

RNA polymerase sigma factor RpoH

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to rpoH

Browse AMR rules for rpoH

Overview

Drug Classes: ceftriaxone
Organisms: Neisseria gonorrhoeae
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A184T	-	-	Neisseria gonorrhoeae	ceftriaxone	Reslit	Candidate

Papers1

1

Genetic identification of mutations and MLST types associated with decreased susceptibility to ceftriaxone in Neisseria gonorrhoeae.

PMID 41648021 · 2025

Mutation in RpoH is associated with ceftriaxone resistance.

Mutation Information

Protein Change: A184T
Organisms: Neisseria gonorrhoeae
Confers Resistance To: ceftriaxone
Validation Method: statistical analysis of amino acid frequencies
Source Database: Reslit