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Browse Genesrpobc

rpobc

RNA polymerase subunits

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to rpobc

Browse AMR rules for rpobc

Validation StatusCandidate

Overview

Validation Method: whole-genome sequencing and MIC testing
Drug Classes: daptomycin
Organisms: Staphylococcus aureus
Papers: 1
Databases: Reslit

Papers1

1

Heterogeneity of genetic pathways toward daptomycin nonsusceptibility in Staphylococcus aureus determined by adjunctive antibiotics.

PMID 25733508 · 2015

Gene Information

Gene Name: rpobc
Allele: rpoBC
Encodes: RNA polymerase subunits
Source Database: Reslit
Confers Resistance To: daptomycin
Organisms Tested In: • Staphylococcus aureus
Validation Method: whole-genome sequencing and MIC testing

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research