rrlB

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ribosomal RNA operon

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to rrlB

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: genomic amplification and expression analysis
Drug Classes: erythromycin
Organisms: Escherichia coli
Papers: 1
Databases: Reslit

Papers1

The Antibiotic Dosage of Fastest Resistance Evolution: Gene Amplifications Underpinning the Inverted-U.

PMID 33693929 · 2021

The study identifies gene amplifications in Escherichia coli, particularly of the acrAB, emrE, and rrlB genes, which contribute to erythromycin resistance under varying antibiotic dosages.

Gene Information

Gene Name: rrlB
Allele: rrlB
Encodes: ribosomal RNA operon
Source Database: Reslit
Confers Resistance To: erythromycin
Organisms Tested In: • Escherichia coli
Validation Method: genomic amplification and expression analysis

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rrlB

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rrlB

Gene Information