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Explore antimicrobial resistance genes from the literature

sapB

permease

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to sapB

Browse AMR rules for sapB

Overview

Drug Classes: daptomycin
Organisms: Enterococcus faecium
Papers: 1
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
G133V	-	-	Enterococcus faecium	daptomycin	Reslit	Candidate
T156I	-	-	Enterococcus faecium	daptomycin	Reslit	Candidate

Papers1

1

Guarding the walls: the multifaceted roles of Bce modules in cell envelope stress sensing and antimicrobial resistance.

PMID 38869304 · 2024

SapB mutations are associated with increased daptomycin resistance.

Mutation Information

sapB: p.G133V sapB: p.T156I

Protein Change: G133V, T156I
Organisms: Enterococcus faecium
Confers Resistance To: daptomycin
Validation Method: reported in cited literature
Source Database: Reslit