The study identifies a novel pseudo-staphylococcal cassette chromosome mec element (ψSCCmec57395) in methicillin-resistant Staphylococcus pseudintermedius CC45, along with various AMR genes such as mecA, blaZ, aac(6')-Ie–aph(2')-Ia, aph(3')-III, ant(6)-Ia, sat4, erm(B), tet(M), dfr(G), and cat pC221. Additionally, fluoroquinolone resistance was linked to specific mutations in gyrA and grlA.

The study identified several AMR genes in Leuconostoc strains, including erm(B) for erythromycin resistance, tet(S) for tetracycline resistance, and others like aadE, aphA-3, sat4, and vat(E) for aminoglycoside and virginiamycin resistance.

The study demonstrates the feasibility of identifying antimicrobial resistance genes through next-generation sequencing of cell-free DNA from plasma samples of septic patients, highlighting the presence of vanB, vanS B, tet1, and sat4 genes in a vancomycin-resistant Enterococcus faecium isolate.

The study identified numerous antibiotic resistance genes in Clostridium bolteae and Clostridium clostridioforme, including beta-lactamases, glycopeptide resistance operons, macrolide and lincosamide resistance genes, and efflux pumps. Notably, C. bolteae 90B3 exhibited resistance to linezolid, chloramphenicol, florfenicol, and tiamulin due to the presence of the 23S rRNA methyltransferase gene cfr. Additionally, C. clostridioforme 90A8 possessed a VanB-type operon conferring vancomycin resistance.

The study identified six resistance genes (aph3', ant6, bla, sat4, and two ermB) on the plasmid pEC369, along with a vanC-2 gene cluster on the chromosome, contributing to resistance against erythromycin, kanamycin, streptomycin, and vancomycin in Enterococcus casseliflavus EC369.

The study identified a dominant PVL-positive ST5-MRSA-IVc clone in Sri Lanka, which was also found in the UK and Australia. The clone exhibited resistance to methicillin, erythromycin, tetracycline, gentamicin, and streptothricin.

The study identified several AMR genes in Enterococcus spp., including erm(B), tet(M), optrA, dfrE, lsa(A), aac(6')-Ib, eat(A), ant(6)-Ia, aph(3')-IIIa, sat4, tet(L), bcrB, bcrC, dfrF, and dfrG, which confer resistance to various antibiotics such as macrolides, tetracyclines, oxazolidinones, trimethoprim, and aminoglycosides.

The study identified multiple horizontally acquired resistance genes in Campylobacter jejuni isolates from New Hampshire, including genes conferring resistance to beta-lactams, aminoglycosides, streptothricin, and tetracycline.

The study identified 55 different antimicrobial resistance determinants in diarrheal pathogens, highlighting the presence of genes conferring resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, macrolides, tetracyclines, phenicols, sulfonamides, and others. Notably, carbapenemase genes like bla OXA-48 and bla NDM were detected in certain isolates, indicating emerging resistance concerns.

The study identifies a gene cluster (aadE*-sat4-aphA-3) in Mycoplasma bovirhinis HAZ141_2 that confers resistance to kanamycin, neomycin, and nourseothricin. The cluster was functionally validated by cloning into E. coli and demonstrating resistance through MIC testing.

The study identified multiple antimicrobial resistance genes in bacterial isolates from chronic non-healing wounds, including beta-lactamases, aminoglycoside modifying enzymes, macrolide resistance genes, and others. These genes were found in various bacterial species such as E. coli, S. aureus, P. aeruginosa, and others.

The study identified several antimicrobial resistance and virulence genes in Enterococcus lacertideformus, including DfrE, EfrB, ClpP, Fss3, and various metal resistance genes such as mgtA, copB, and ziaA. These genes suggest resistance to trimethoprim, macrolides, rifamycins, fluoroquinolones, and heavy metals.

This study identifies multiple AMR genes and mutations in Clostridioides difficile, including ermB, tetM, mefH, and various mutations in gyrA, gyrB, rpoB, pbp1, and pbp3. These findings highlight the widespread nature of AMR in C. difficile and its potential role in the spread of the bacterium.

The aadE*-sat4-aphA-3 gene cluster in Mycoplasma bovirhinis HAZ141_2 undergoes genomic rearrangements, including inversions and deletions, which affect the primary promoter sequence and influence gene expression. The genes aadE*, sat4, and aphA-3 confer resistance to streptomycin, streptothricin/nourseothricin, and kanamycin/neomycin, respectively.

The study identifies a novel variant of the aadE-sat4-aphA-3 gene cluster in the conjugative plasmid pCjH01 from a multidrug-resistant Campylobacter jejuni isolate, which provides resistance to kanamycin and gentamicin.

The study identified several AMR genes in Enterococcus hirae isolates from beef cattle feedlots, including tetracycline resistance genes (tet(L), tet(M), tet(O), tet(S/M), tet(O/32/O)), macrolide resistance gene erm(B), and aminoglycoside resistance genes (aac(6')-Iid, ant(6)-Ia, aph(3')-III, sat4).

The study identifies various AMR genes such as mecA, blaZ, tet(M), erm(B), aac(6')-aph(2"), aadD, ant(6)-Ia, and sat4 in Staphylococcus aureus and S. pseudintermedius isolates from healthy dogs and cats, indicating widespread antibiotic resistance.

The study identified multiple beta-lactam resistance genes (blaOXA variants), tetracycline resistance gene tet(O), aminoglycoside resistance genes (aadE, aph(3')-IIIa, sat4), and a fluoroquinolone resistance mutation (gyrA T86I) in Campylobacter jejuni isolates from German turkey flocks.

The study identified several AMR genes and mutations in Campylobacter isolates from Italian poultry, highlighting the emergence of multidrug-resistant strains and the prevalence of specific resistance mechanisms such as the T86I mutation in gyrA and the tet(O) gene.

The study identifies several antimicrobial resistance genes in Enterococcus species isolated from livestock in South Africa, highlighting the presence of multidrug-resistant strains and emphasizing the need for genomic surveillance to monitor the spread of antimicrobial resistance in food chain animals.

The study identified 21 resistance determinants in MRSP and MSSP strains of Staphylococcus pseudintermedius, including genes such as blaZ, sdrM, norA, fosB, ykkcd, sepA, aac(6')-aph(2''), dfrG, aph(3')-III, ant(6)-Ia, sat4, erm(B), aad(6), tet(M), cat(pC221), qacG, tet(K), and qacJ, which confer resistance to various antimicrobials.

The study identified several antibiotic resistance genes in Staphylococcus aureus isolates from both patients and retail meat, including blaZ, fosB-Saur, tet38, mphC, msrA, sat4, mecA, aph(3')-IIIa, and fusC. These genes were associated with resistance to various antibiotics such as penicillin, tetracycline, macrolides, and fusidic acid.

The study identified 22 different resistance genes and gene variants, including erm(B), aph(3')-IIIa, aadE, catA, lnu(C), blaOXA, sat4, tet(O), and point mutations in gyrA, 23S rRNA, and rpsL, associated with antimicrobial resistance in thermotolerant Campylobacter spp.

The study identified novel methicillin-resistant Staphylococcus pseudintermedius (MRSP) lineages, including ST726 and ST551, and characterized antimicrobial resistance genes such as mecA, blaZ, tetK, and mupA. It also noted a high prevalence of multidrug resistance (MDR) among MRSP isolates.

The study identifies beta-lactam resistance genes blaOXA-193 and blaOXA-184, as well as the multidrug efflux pump operon cmeABCR in Campylobacter jejuni isolates from Brazil. Mutations in gyrA and rrn genes are associated with quinolone and macrolide resistance.

The study identified 14 resistance genes in Campylobacter jejuni and Campylobacter coli isolates, including genes conferring resistance to tetracycline, beta-lactams, and aminoglycosides. Mutations in gyrA, rplV, 23S rRNA, and rpsL were also associated with resistance to fluoroquinolones, macrolides, and aminoglycosides.

The study identified several AMR genes in methicillin-resistant Staphylococcus aureus (MRSA) isolates from pets, dairies, and humans, including mecA, tet(M), tet(K), erm(C), erm(A), mph(C), msr(A), blaR1, blaZ, blaI_of_Z, blaPC1, vga(A), fosB-Saur, sat4, bleO, ant(9)-Ia, aph(2'')-Ih, aph(3')-IIIa, and ant(4')-Ia. These genes confer resistance to various antibiotics such as methicillin, tetracycline, erythromycin, macrolides, lincomycin, fosfomycin, streptothricin, bleomycin, spectinomycin, amikacin, gentamicin, kanamycin, tobramycin, and others.

AmrProfiler identifies a wide range of AMR genes and mutations across multiple bacterial species, demonstrating high accuracy and broader species coverage compared to existing tools.

The study identified several AMR genes and mutations in Campylobacter jejuni isolates from chicken livers, including blaOXA-185 and blaOXA-61 for beta-lactam resistance, tet(O) for tetracycline resistance, and CmeABC efflux pump for multidrug resistance. Additionally, a point mutation T86I in the gyrA gene was linked to ciprofloxacin resistance.

The study identified several AMR genes and mutations in Staphylococcus isolates from small- to medium-scale and large-scale dairy farms in Thailand, highlighting differences in resistance profiles between farm types.

Three Staphylococcus pseudintermedius isolates from dogs and humans in Egypt were characterized. The isolates showed resistance to various antibiotics, including penicillin, tetracycline, aminoglycosides, chloramphenicol, fusidic acid, macrolides, streptothricin, and trimethoprim. None of the isolates carried the mecA gene, which is associated with methicillin resistance.