sbmC

View on PubMed

DNA gyrase inhibitor

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to sbmC

AMR Rules

Browse AMR rules for sbmC

Validation StatusCandidate

Overview

Mechanism: inhibits DNA gyrase
Validation Method: overexpression in E. coli and resistance measurement
Drug Classes: phleomycin
Organisms: Escherichia coli
Papers: 1
Databases: Reslit

Papers1

Nonoptimal Gene Expression Creates Latent Potential for Antibiotic Resistance.

PMID 30169679 · 2018

The study identifies numerous genes whose expression changes can confer resistance to various antibiotics, highlighting the role of nonoptimal gene expression in antibiotic resistance development.

Gene Information

Gene Name: sbmC
Allele: sbmC
Encodes: DNA gyrase inhibitor
Source Database: Reslit
Mechanism: inhibits DNA gyrase
Confers Resistance To: phleomycin
Organisms Tested In: • Escherichia coli
Validation Method: overexpression in E. coli and resistance measurement

Comments (0)

No comments yet. Be the first to comment!

sbmC

Gene Information

Browse AMR Genes

sbmC

Gene Information