sgtB

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peptidoglycan transferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to sgtB

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: mutation
Validation Method: genomic studies
Drug Classes: oxacillin
Organisms: Staphylococcus aureus
Papers: 1
Databases: Reslit

Papers1

Case Commentary: The hidden side of oxacillin resistance in Staphylococcus aureus.

PMID 37655923 · 2023

The paper discusses the development of mec-independent oxacillin resistance in Staphylococcus aureus, highlighting the role of mutations in cell wall metabolism genes such as gdpP, clpX, and sgtB.

Gene Information

Gene Name: sgtB
Allele: sgtB
Encodes: peptidoglycan transferase
Source Database: Reslit
Mechanism: mutation
Confers Resistance To: oxacillin
Organisms Tested In: • Staphylococcus aureus
Validation Method: genomic studies

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sgtB

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sgtB

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