smdab

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ATP-binding cassette (ABC)-type multidrug efflux pump

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Validation StatusCandidate

Overview

Validation Method: cloning in E. coli + MIC testing
Drug Classes: norfloxacin, tetracycline
Organisms: Escherichia coli, Serratia marcescens
Papers: 1
Databases: Reslit

Papers1

SmdAB, a heterodimeric ABC-Type multidrug efflux pump, in Serratia marcescens.

PMID 18024518 · 2008

The study identifies SmdAB, an ABC-type multidrug efflux pump in Serratia marcescens, which confers resistance to multiple antimicrobial agents including norfloxacin, tetracycline, DAPI, and Hoechst 33342 when expressed in E. coli.

Gene Information

Gene Name: smdab
Allele: smdAB
Encodes: ATP-binding cassette (ABC)-type multidrug efflux pump
Source Database: Reslit
Confers Resistance To: norfloxacintetracycline
Organisms Tested In: • Escherichia coli
• Serratia marcescens
Validation Method: cloning in E. coli + MIC testing
Sequence Accession: AB360548

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smdab

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smdab

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