smeC

resistance-nodulation-cell division (RND) antibiotic efflux pump

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic efflux
Validation Method: overexpression studies
Drug Classes: ceftazidime, ticarcillin clavulanic acid
Organisms: Stenotrophomonas maltophilia, Stenotrophomonas maltophilia K279a
Papers: 1
Databases: Card DatabaseReslit

Papers1

PMID N/A

Gene Information

Gene Name: smeC
Allele: smeC
Encodes: resistance-nodulation-cell division (RND) antibiotic efflux pump
Source Database: Card Database
Mechanism: antibiotic efflux
Organisms Tested In: • Stenotrophomonas maltophilia
Sequence Accession: AF173226.1
Protein Accession: AAD51346.1
Notes: ARO:3003053

Role of RND Efflux Pumps in Drug Resistance of Cystic Fibrosis Pathogens.

PMID 34356783 · 2021

The study highlights the critical role of RND efflux pumps in mediating multidrug resistance in cystic fibrosis pathogens, particularly in Pseudomonas aeruginosa and Burkholderia cenocepacia. Several RND efflux systems were identified and characterized for their contributions to resistance against various antibiotics.

Gene Information

Gene Name: smeC
Allele: smeC
Encodes: efflux pump component
Source Database: Reslit
Confers Resistance To: ceftazidimeticarcillin clavulanic acid
Organisms Tested In: • Stenotrophomonas maltophilia K279a
Validation Method: overexpression studies

Comments (0)

No comments yet. Be the first to comment!

smeC

Gene Information

Gene Information

Browse AMR Genes

smeC

Gene Information

Gene Information