Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
ABC-type efflux pump
Overview
Acquired resistance of Stenotrophomonas maltophilia to antimicrobials induced by herbicide paraquat dichloride.
Exposure of Stenotrophomonas maltophilia to paraquat induces multidrug resistance through genetic mutations affecting efflux pumps, ribosomal proteins, and metabolic enzymes.
Screening and comparison of in vitro-induced resistant and clinically resistant Stenotrophomonas maltophilia strains for eravacycline resistance-related genes.
The study identified the upregulation of efflux pump genes (smrA, smeD, smeE, smeF) in eravacycline-resistant Stenotrophomonas maltophilia strains, along with copy number variations and nonsynonymous mutations in smeD, smeE, and smeF contributing to resistance.
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