speG

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spermidine acetyltransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to speG

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: functional analysis using B. subtilis as a host
Drug Classes: clindamycin
Organisms: Bacillus licheniformis, Bacillus paralicheniformis, Bacillus subtilis
Geographic Location: Korea
Papers: 1
Databases: Reslit

Papers1

Two genes involved in clindamycin resistance of Bacillus licheniformis and Bacillus paralicheniformis identified by comparative genomic analysis.

PMID 32271828 · 2020

The study identified ermC and speG as genes contributing to clindamycin resistance in Bacillus licheniformis and Bacillus paralicheniformis. ermC confers cross-resistance to clindamycin and erythromycin, while speG confers resistance to clindamycin.

Gene Information

Gene Name: speG
Allele: speG
Encodes: spermidine acetyltransferase
Source Database: Reslit
Confers Resistance To: clindamycin
Organisms Tested In: • Bacillus licheniformis
• Bacillus paralicheniformis
• Bacillus subtilis
Geographic Location: Korea
Validation Method: functional analysis using B. subtilis as a host
Sequence Accession: NZ_CP023168|LBMN02000039|NC_006270|CP026673|CP031126

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speG

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speG

Gene Information