spoVG

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transcriptional regulator

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Validation StatusCandidate

Overview

Mechanism: regulates cell wall metabolism and oxacillin resistance
Validation Method: deletion and complementation experiments
Drug Classes: oxacillin
Organisms: Staphylococcus aureus
Papers: 1
Databases: Reslit

Papers1

SpoVG Regulates Cell Wall Metabolism and Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus Strain N315.

PMID 27001809 · 2016

SpoVG regulates cell wall metabolism and oxacillin resistance in MRSA strain N315 by directly binding to the promoter regions of lytN, femA, and lytSR, thereby influencing the expression of genes involved in cell wall synthesis and degradation.

Gene Information

Gene Name: spoVG
Allele: spoVG
Encodes: transcriptional regulator
Source Database: Reslit
Mechanism: regulates cell wall metabolism and oxacillin resistance
Confers Resistance To: oxacillin
Organisms Tested In: • Staphylococcus aureus
Validation Method: deletion and complementation experiments

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spoVG

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spoVG

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