Browse AMR Genes

Explore antimicrobial resistance genes from the literature

spr0188

50S ribosomal protein L3

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to spr0188

Browse AMR rules for spr0188

Overview

Drug Classes: linezolid
Organisms: Streptococcus pneumoniae
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
Y137H	T409C	-	Streptococcus pneumoniae	linezolid	Reslit	Candidate

Papers1

1

Whole genome analysis of linezolid resistance in Streptococcus pneumoniae reveals resistance and compensatory mutations.

PMID 22004526 · 2011

Mutation Information

spr0188: p.Y137H / c.T409C

Protein Change: Y137H
Nucleotide Change: T409C
Organisms: Streptococcus pneumoniae
Confers Resistance To: linezolid
Validation Method: transformation and MIC testing
Source Database: Reslit