stkP

serine threonine kinase

Overview

Drug Classes: penicillin
Organisms: Streptococcus pneumoniae
Papers: 1
Mutations: 4

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A113V	-	-	Streptococcus pneumoniae	penicillin	Reslit	Candidate
N227K	-	-	Streptococcus pneumoniae	penicillin	Reslit	Candidate
S237P	-	-	Streptococcus pneumoniae	penicillin	Reslit	Candidate
-	CGT->AAA	-	Streptococcus pneumoniae	penicillin	Reslit	Candidate

Papers1

The highly conserved serine threonine kinase StkP of Streptococcus pneumoniae contributes to penicillin susceptibility independently from genes encoding penicillin-binding proteins.

PMID 19500353 · 2009

Mutation in stkP leads to hypersensitivity to penicillin

Mutation Information

stkP: p.A113V stkP: p.N227K stkP: p.S237P stkP: c.CGT->AAA

Protein Change: A113V, N227K, S237P
Nucleotide Change: CGT->AAA
Organisms: Streptococcus pneumoniae
Confers Resistance To: penicillin
Validation Method: genetic analysis in laboratory transformable strain Cp1015
Source Database: Reslit

stkP

Mutations

Mutation Information

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stkP

Mutations

Mutation Information