Browse AMR Genes

Explore antimicrobial resistance genes from the literature

sulR

flavin reductase SulR

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to sulR

Browse AMR rules for sulR

Validation StatusConfirmed2+ DBs

Overview

Validation Method: gene expression and biochemical analysis
Drug Classes: SULFONAMIDE, sulfonamides
Organisms: Microbacterium sp. C448, Microbacterium sp. CJ77
Papers: 2
Databases: Reference Gene CatalogReslit

Papers2

1

Draft Genome Sequence of the Sulfonamide Antibiotic-Degrading Microbacterium sp. Strain C448.

PMID 24526651 · 2014

Gene Information

Gene Name: sulR
Allele: SulR
Encodes: flavin reductase SulR
Source Database: Reference Gene Catalog
Confers Resistance To: SULFONAMIDE
Organisms Tested In: • Microbacterium sp. C448
Sequence Accession: CBVQ010000037.1
Protein Accession: CDJ99306.1

2

Monooxygenases and Antibiotic Resistance: A Focus on Carbapenems.

PMID 37887026 · 2023

This review discusses the role of flavin-dependent monooxygenases (FMOs) and Baeyer-Villiger monooxygenases (BVMOs) in antibiotic resistance, focusing on their mechanisms in modifying antibiotics such as tetracyclines, rifamycins, and sulfonamides. Key genes like TetX, MabTetX, Tet56, RIFMO, SadA, SadB, SulX, and SulR were identified as conferring resistance through enzymatic modifications.

Gene Information

Gene Name: sulR
Allele: SulR
Encodes: flavin reductase
Source Database: Reslit
Confers Resistance To: sulfonamides
Organisms Tested In: • Microbacterium sp. CJ77
Validation Method: gene expression and biochemical analysis

3

Monooxygenases and Antibiotic Resistance: A Focus on Carbapenems.

PMID 37887026 · 2023

This review discusses the role of flavin-dependent monooxygenases (FMOs) and Baeyer-Villiger monooxygenases (BVMOs) in antibiotic resistance, focusing on their mechanisms in modifying antibiotics such as tetracyclines, rifamycins, and sulfonamides. Key genes like TetX, MabTetX, Tet56, RIFMO, SadA, SadB, SulX, and SulR were identified as conferring resistance through enzymatic modifications.

Gene Information

Gene Name: sulR
Allele: SulR
Encodes: flavin reductase
Source Database: Reslit
Confers Resistance To: sulfonamides
Organisms Tested In: • Microbacterium sp. CJ77
Validation Method: gene expression and biochemical analysis

Comments (0)

No comments yet. Be the first to comment!