Browse AMR Genes

Explore antimicrobial resistance genes from the literature

tctA

citrate transporter

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to tctA

Browse AMR rules for tctA

Overview

Drug Classes: sulfamethoxazole
Organisms: Comamonas testosteroni
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
L234P	-	-	Comamonas testosteroni	sulfamethoxazole	Reslit	Candidate

Papers1

1

Epigenetic modifications and metabolic gene mutations drive resistance evolution in response to stimulatory antibiotics.

PMID 39820016 · 2025

Mutations in TctA were associated with resistance development.

Mutation Information

Protein Change: L234P
Organisms: Comamonas testosteroni
Confers Resistance To: sulfamethoxazole
Validation Method: site-directed mutagenesis and ZEP assay
Source Database: Reslit