tdk

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thymidine kinase/deoxyuridine kinase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to tdk

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Validation StatusCandidate

Overview

Validation Method: transposon insertion mutagenesis and competition assays
Drug Classes: trimethoprim
Organisms: Escherichia coli
Papers: 1
Databases: Reslit

Papers1

Chemical biology-whole genome engineering datasets predict new antibacterial combinations.

PMID 34874820 · 2021

The study identifies genes such as tdk and ispD that influence susceptibility to trimethoprim and sulfamethoxazole through transposon insertion mutagenesis and competition assays.

Gene Information

Gene Name: tdk
Allele: tdk
Encodes: thymidine kinase/deoxyuridine kinase
Source Database: Reslit
Confers Resistance To: trimethoprim
Organisms Tested In: • Escherichia coli
Validation Method: transposon insertion mutagenesis and competition assays

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tdk

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tdk

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