Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
major facilitator superfamily (MFS) antibiotic efflux pump
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| tet(33) | Card DatabaseResFinder Database | 2 | TETRACYCLINE, DOXYCYCLINE | Corynebacterium glutamicum +1 | - | 2003 | AJ420072.1 | CAD12227.2 |
| Tet(33) | Card DatabaseReference Gene CatalogReslit | 10 | TETRACYCLINE, tetracycline +1 | Corynebacterium glutamicum +7 | Denmark, Europe, United States, France|South Asia|Thailand|Malaysia|Belarus|Spain|Australia|Guatemala|India|Romania|Russia|USA, North America, Europe|Midwestern United States, Victoria, Australia | 2002, 2005, 2006, 2011, 2019, 2023, 2025 | AJ420072.1 | CAD12227.2 |
| tet33 | Reslit | 2 | tetracycline, oxytetracycline | Corynebacterium diphtheriae +1 | France|New Caledonia|La Réunion Island|French Guiana|French Polynesia|Guadeloupe|Madagascar|Tunisia|India, China | 2020, 2021 | NC_002935.2 | - |
| Tet33 | Reslit | 1 | tetracycline | Trueperella pyogenes | India|Iran|UK|China|Brazil|US|Australia | 2022 | PESV00000000 | - |
The 27.8-kb R-plasmid pTET3 from Corynebacterium glutamicum encodes the aminoglycoside adenyltransferase gene cassette aadA9 and the regulated tetracycline efflux system Tet 33 flanked by active copies of the widespread insertion sequence IS6100.
The 27.8-kb R-plasmid pTET3 from Corynebacterium glutamicum encodes the aminoglycoside adenyltransferase gene cassette aadA9 and the regulated tetracycline efflux system Tet 33 flanked by active copies of the widespread insertion sequence IS6100.
Tylosin resistance in Arcanobacterium pyogenes is encoded by an erm X determinant., Facile recovery of individual high-molecular-weight, low-copy-number natural plasmids for genomic sequencing.
Class 1 integrons and tetracycline resistance genes in alcaligenes, arthrobacter, and Pseudomonas spp. isolated from pigsties and manured soil.
The study identifies several tetracycline resistance genes (tet(A), tet(C), tet(33)) and gene cassettes (aadA1, aadA2, aadA9, aadA11, dfrA1, dfrB2a) associated with class 1 integrons in various bacterial species isolated from pigsties and manured soil.
Facile recovery of individual high-molecular-weight, low-copy-number natural plasmids for genomic sequencing.
Environmental macrolide-lincosamide-streptogramin and tetracycline resistant bacteria.
The paper discusses the characterization of environmental macrolide-lincosamide-streptogramin (MLS) and tetracycline resistance genes, highlighting the diversity and distribution of these genes in environmental bacteria. It identifies several MLS resistance genes such as erm(H), erm(I), erm(N), and others, as well as tetracycline resistance genes like tetA(P), tet(V), and tet(X).
Investigating the dispersal of antibiotic resistance associated genes from manure application to soil and drainage waters in simulated agricultural farmland systems.
The study identified the tet(33) gene as a persistent antibiotic resistance gene in manure-treated soil and drainage water, highlighting its potential for long-term environmental persistence and dissemination.
Population genomics and antimicrobial resistance in Corynebacterium diphtheriae.
The study identifies several AMR genes in Corynebacterium diphtheriae, including pbp2m associated with penicillin resistance, ermX for macrolide resistance, and various genes for tetracycline, aminoglycoside, and sulfonamide resistance.
Genomic insights into the antibiotic resistance pattern of the tetracycline-degrading bacterium, Arthrobacter nicotianae OTC-16.
The study identifies several antibiotic resistance genes in Arthrobacter nicotianae OTC-16, including ant2ia, sul1, tet33, cml_e8, and tetV, which confer resistance to various antibiotics such as tetracyclines, sulfonamides, aminoglycosides, and chloramphenicol.
Comparative Genome Analysis of 19 Trueperella pyogenes Strains Originating from Different Animal Species Reveal a Genetically Diverse Open Pan-Genome.
The study identified 40 antibiotic resistance genes (ARGs) in 19 Trueperella pyogenes strains, including genes conferring resistance to aminoglycosides, tetracyclines, phenicols, sulfonamides, and macrolides.
Multidrug-resistant toxigenic Corynebacterium diphtheriae sublineage 453 with two novel resistance genomic islands.
Two multidrug-resistant toxigenic Corynebacterium diphtheriae isolates were analyzed, revealing two novel resistance genomic islands carrying 12 resistance genes, including ermX, cmx, aph(3')-Ib, aph(6)-Id, aadA1, dfrA15, sul1, cmlA, cmlR, and tet(33). Additionally, mutations in rpoB and gyrA were associated with resistance to rifampicin and ciprofloxacin, respectively.
Impact of doxycycline post-exposure prophylaxis for sexually transmitted infections on the gut microbiome and antimicrobial resistome.
The study found that doxy-PEP use over 6 months significantly increased the proportion and expression of tetracycline resistance genes in the gut microbiome, with no significant changes in other antibiotic resistance gene classes.
Genomic and metabolic characterization of Trueperella pyogenes isolated from domestic and wild animals.
The study identified multiple antimicrobial resistance (AMR) genes in Trueperella pyogenes, including tet(W/32/O), erm(X), vanG, sul1, and qacEdelta1, which confer resistance to tetracyclines, MLS B, glycopeptides, sulfonamides, and biocides, respectively. These genes were detected in various T. pyogenes isolates from different animal hosts and body sites, highlighting the genetic diversity and potential for AMR dissemination among different hosts.
Population structure and antimicrobial resistance of Corynebacterium diphtheriae in Victoria, Australia.
The study identified multiple AMR genes and mutations in contemporary Corynebacterium diphtheriae isolates from Victoria, Australia, including pbp2m, erm(X), aph(3')-Ia, aph(6)-Id, aph(3'')-Ib, tet(W), tet(33), tet(O), cmx, sul1, dfrA15, and mutations in gyrA and rpoB. These genes and mutations confer resistance to various antimicrobials such as penicillin, erythromycin, gentamicin, tetracycline, chloramphenicol, sulfamethoxazole, trimethoprim, ciprofloxacin, and rifampicin.
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