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Explore antimicrobial resistance genes from the literature

tet(53)

tetracycline inactivation enzyme

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to tet(53)

Browse AMR rules for tet(53)

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic inactivation
Drug Classes: MINOCYCLINE, TETRACYCLINE
Organisms: uncultured bacterium
Alleles: 2
Papers: 1
Databases: Card DatabaseReference Gene CatalogResFinder Database

Allele Variants2

Allele	Database	Papers	Drug Classes	Organisms	Countries	Years	Sequence Accession	Protein Accession
tet(53)	Card DatabaseResFinder Database	2	MINOCYCLINE, TETRACYCLINE	uncultured bacterium	-	2015	KR857687.1	AKQ05897.1
Tet(53)	Card DatabaseReference Gene CatalogResFinder Database	3	MINOCYCLINE, TETRACYCLINE	uncultured bacterium	-	2015	KR857687.1	AKQ05897.1

Papers1

1

Gene Information

Gene Name: tet(53)
Allele: tet(53)
Encodes: tetracycline inactivation enzyme
Source Database: Card Database
Mechanism: antibiotic inactivation
Organisms Tested In: • uncultured bacterium
Sequence Accession: KR857687.1
Protein Accession: AKQ05897.1
Notes: ARO:3004589

2

The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.

PMID 26097034 · 2015

Gene Information

Gene Name: tet(53)
Allele: Tet(53)
Encodes: tetracycline destructase Tet(53)
Source Database: Reference Gene Catalog
Mechanism: Enzymatic inactivation
Confers Resistance To: MINOCYCLINETETRACYCLINE
Organisms Tested In: • uncultured bacterium
Sequence Accession: KR857687.1
Protein Accession: AKQ05897.1
Notes: ARO:3004589

3

The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.

PMID 26097034 · 2015

Gene Information

Gene Name: tet(53)
Allele: Tet(53)
Encodes: tetracycline destructase Tet(53)
Source Database: ResFinder Database
Mechanism: Enzymatic inactivation
Confers Resistance To: MINOCYCLINETETRACYCLINE
Organisms Tested In: • uncultured bacterium
Sequence Accession: KR857687.1
Protein Accession: AKQ05897.1
Notes: ARO:3004589

4

The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.

PMID 26097034 · 2015

Gene Information

Gene Name: tet(53)
Allele: Tet(53)
Encodes: tetracycline destructase Tet(53)
Source Database: Card Database
Mechanism: Enzymatic inactivation
Confers Resistance To: MINOCYCLINETETRACYCLINE
Organisms Tested In: • uncultured bacterium
Sequence Accession: KR857687.1
Protein Accession: AKQ05897.1
Notes: ARO:3004589

5

The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.

PMID 26097034 · 2015

Gene Information

Gene Name: tet(53)
Allele: tet(53)
Source Database: ResFinder Database
Mechanism: Enzymatic inactivation
Confers Resistance To: MINOCYCLINETETRACYCLINE
Organisms Tested In: • uncultured bacterium
Sequence Accession: KR857687

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