Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
tetracycline efflux MFS transporter Tet(63)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Tet(63) | Card DatabaseReference Gene CatalogReslit | 4 | TETRACYCLINE, tetracycline +4 | Staphylococcus aureus | Europe|United States|Asia, China | 2022, 2023 | CP053076.1 | QJR33972.1 |
| tet(63) | Card Database | 1 | - | Staphylococcus aureus | - | - | CP053076.1 | QJR33972.1 |
Molecular Mechanisms of Drug Resistance in Staphylococcus aureus.
The paper discusses the molecular mechanisms of drug resistance in Staphylococcus aureus, focusing on beta-lactam, glycopeptide, oxazolidinone, MLS-B, aminoglycoside, and other resistance mechanisms. Key genes identified include blaZ, mecA, mecC, vanA, cfr, ermA, ermC, aac(6')-Ib, aph(3')-IIIa, and aadD. Mutations in pbp2 and pbp2a were also found to contribute to resistance.
Exploring the third-generation tetracycline resistance of multidrug-resistant livestock-associated methicillin-resistant Staphylococcus aureus ST9 across healthcare settings in China.
The study identifies the tetracycline resistance genes tet(L) and tet(63) and the rpsJ Y58D mutation as responsible for third-generation tetracycline resistance in multidrug-resistant ST9 MRSA isolates.
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