Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
tetracycline efflux MFS transporter Tet(C)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Tet(C) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 58 | TETRACYCLINE, DOXYCYCLINE +3 | Francisella tularensis +46 | United States, North Carolina|Ohio, Denmark, United Kingdom, China, USA|Italy, Canada, South Korea, Denmark|Europe, Italy, USA|Europe|Middle East, Europe, United States|Italy|Belgium|Cyprus|Germany|Israel|Switzerland|The Netherlands, Europe|United States|China|Brazil|Australia|Spain|Germany|Iran|Switzerland|France|Portugal|Japan|Belgium|South Korea|Vietnam|Taiwan|India|Egypt|South Africa|Algeria, China|Three Gorges Reservoir (TGR), China, USA|Peru|Egypt|Cambodia|Kenya, Shanxi Province, China, Ontario, Canada|North America, Sicily|Italy, Basque Country, northern Spain|Basque Country, Brazil, Argentina|Australia|Brazil|China|India|United States, Kenya, Spain|Asturias, Spain, West Texas, USA, India, Switzerland, Bulgaria, Europe|Asia|South America|Africa|Germany|Vietnam|USA|Ecuador|China, California, China|North America|Asia|Europe|Africa|Other, United States|Europe|Russia|Canada|Australia|global, Africa | 1999, 2002, 2003, 2004, 2005, 2007, 2008, 2009, 2010, 2011, 2015, 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025 | AF055345.1 | AAC12938.1 |
| tet(C) | Card DatabaseResFinder Database | 2 | TETRACYCLINE, DOXYCYCLINE | Aeromonas salmonicida +1 | - | 2002 | AY043299.1 | AAK97755.1 |
| tetC | Reslit | 85 | tetracycline, oxytetracycline +2 | Photobacterium +64 | Japan, United States, Canada, Korea, Maine|New Hampshire, United States|Switzerland|Czech Republic|New Zealand, USA|Brazil|United States, China, France, Poland, Eastern Cape, South Africa, UK|Cyprus, Egypt, South Korea, Southern Alberta, Canada, Germany, UK, South Africa, Tai'an, China, Norway, Spain|porcine, Brazil, Spain, Europe, Norway|China, Colombia, Malaysia, Thailand, New York State, Bangladesh, South Carolina, Georgia, USA|Georgia, Europe|USA|Portugal|Germany|Australia|China|India|Pakistan|Sweden|Colorado, South Africa|Europe, Romania|Cluj County, North Western Romania, Shijiazhuang, Hebei Province, Indonesia, Northern Pacific Ocean|Norway Sea|Europe, swine manure, Atlantic salmon, Sicily, Mexico|Japan|China|Israel|New Zealand|United States, India, Anhui province, China, Europe|Poland, California, Northwestern Transylvania, Romania, Abruzzo region, Italy, Northern Italy, China|Lebanon|United States|Poland|France, Pakistan | 2003, 2006, 2009, 2010, 2011, 2012, 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025 | AB089585|AB089586|AB089587|AB089588|AB089589|AB089590|AB089591|AB089592|AB089593|AB089594|AB089595|AB089596|AB089597|AB089598|AB089599|AB089600|AB089601|AB089602|AB089603|AB089604|AB089605|AB089606|AB089607|AB089608 | - |
| tet (C) | Reslit | 2 | tetracycline | Escherichia coli | United Kingdom, Italy | 2019, 2024 | PRJEB26317 | - |
| tet C | Reslit | 2 | tetracycline | Escherichia coli | Europe, Saudi Arabia | 2021, 2022 | - | - |
In vitro and in vivo antibacterial activities of a novel glycylcycline, the 9-t-butylglycylamido derivative of minocycline (GAR-936).
The study characterizes the in vitro and in vivo antibacterial activities of TBG-MINO, a novel glycylcycline, against various tetracycline-resistant strains, including those with tet(A), tet(B), tet(C), tet(D), tet(K), and tet(M) resistance determinants.
Development, validation, and application of PCR primers for detection of tetracycline efflux genes of gram-negative bacteria.
The study developed and validated PCR primers for detecting tetracycline efflux genes in gram-negative bacteria, identifying multiple tet genes in swine feed, feces, and groundwater, highlighting the spread of tetracycline resistance in agricultural environments.
A global non-conjugative Tet C plasmid, pRAS3, from Aeromonas salmonicida.
A global non-conjugative Tet C plasmid, pRAS3, from Aeromonas salmonicida.
A global non-conjugative Tet C plasmid, pRAS3, from Aeromonas salmonicida.
A global non-conjugative Tet C plasmid, pRAS3, from Aeromonas salmonicida.
A global non-conjugative Tet C plasmid, pRAS3, from Aeromonas salmonicida., The region of the IncN plasmid R46 coding for resistance to beta-lactam antibiotics, streptomycin/spectinomycin and sulphonamides is closely related to antibiotic resistance segments found in IncW plasmids and in Tn21-like transposons., Nucleotide sequence, structural organization, and functional characterization of the small recombinant plasmid pOM1 that is specific for Francisella tularensis.
Similarity of tetracycline resistance genes isolated from fish farm bacteria to those from clinical isolates.
The study identified tetracycline resistance genes (tetB, tetC, tetD, tetY, and tetG) in fish farm bacteria that are similar to those found in clinical isolates, indicating a shared origin of these resistance genes.
Novel classical MHC class I alleles identified in horses by sequencing clones of reverse transcription-PCR products.
Effects of efflux transporter genes on susceptibility of Escherichia coli to tigecycline (GAR-936).
The study identified several efflux transporter genes, including tet(B), tet(C), tet(K), acrAB, acrEF, and bcr, that influence the susceptibility of Escherichia coli to tigecycline. While tigecycline was effective against strains expressing these efflux pumps, it was found to be a substrate for AcrAB and AcrEF, suggesting potential resistance mechanisms.
Tetracycline Resistance in Chlamydia suis Mediated by Genomic Islands Inserted into the Chlamydial inv-Like Gene.
The study identifies the tet(C) gene as the tetracycline resistance determinant in Chlamydia suis, which is integrated into the chlamydial chromosome within genomic islands.
Tetracycline resistance in Chlamydia suis mediated by genomic islands inserted into the chlamydial inv-like gene.
Development and Application of Real-Time PCR Assays for Quantification of Genes Encoding Tetracycline Resistance
The study developed and validated real-time PCR assays to quantify ten major classes of tetracycline resistance genes (tet) in microbiome samples, revealing significant differences in tet gene abundance between bovine and swine manures, with swine manures showing higher levels. Composting significantly reduced tet gene abundance.
Class 1 integrons and tetracycline resistance genes in alcaligenes, arthrobacter, and Pseudomonas spp. isolated from pigsties and manured soil.
The study identifies several tetracycline resistance genes (tet(A), tet(C), tet(33)) and gene cassettes (aadA1, aadA2, aadA9, aadA11, dfrA1, dfrB2a) associated with class 1 integrons in various bacterial species isolated from pigsties and manured soil.
Biochemical and molecular characterization of tetracycline-resistant Aeromonas veronii isolates from catfish.
The study identified tetE as the predominant tetracycline resistance gene in Aeromonas veronii isolates from catfish, followed by tetB, tetA, tetC, and tetD.
Monitoring and Source Tracking of Tetracycline Resistance Genes in Lagoons and Groundwater Adjacent to Swine Production Facilities over a 3-Year Period
The study identified and characterized seven tetracycline resistance genes (tet(M), tet(O), tet(Q), tet(W), tet(C), tet(H), and tet(Z)) in lagoons and groundwater near swine production facilities over a 3-year period. These genes were consistently detected in groundwater and lagoon samples, with varying frequencies and concentrations depending on the location and sampling time.
Evaluating the effects of chlortetracycline on the proliferation of antibiotic-resistant bacteria in a simulated river water ecosystem.
The study found that high concentrations of chlortetracycline (CTC) selected for increased tetracycline resistance in aerobic bacterial populations, with a greater diversity of tet resistance genes detected in the high-CTC chemostat compared to low-CTC and control chemostats.
Complete genome sequence and comparative analysis of the wild-type commensal Escherichia coli strain SE11 isolated from a healthy adult.
Tetracycline Resistome of the Organic Pig Gut
The study identified known tetracycline resistance genes (tet(C), tet(W), tet(40)) and novel genes (galE1 and galE2) that confer resistance to tetracycline derivatives minocycline and doxycycline in the organic pig gut microbiome.
Antimicrobial resistance genes in Escherichia coli isolates recovered from a commercial beef processing plant
The study identified various antimicrobial resistance genes in E. coli isolates from a commercial beef processing plant, including beta-lactamase genes (blaCMY, blaSHV, blaTEM), tetracycline resistance genes (tetA, tetB, tetC), sulfonamide resistance genes (sul1, sul2), and aminoglycoside resistance genes (strA, strB).
Longitudinal characterization of resistant Escherichia coli in fecal deposits from cattle fed subtherapeutic levels of antimicrobials.
The study identified several AMR genes, including blaTEM1, tetA, tetB, tetC, sul1, and sul2, in Escherichia coli from cattle fecal deposits. These genes conferred resistance to ampicillin, tetracycline, and sulfonamides.
Antibiotic resistance characteristics of environmental bacteria from an oxytetracycline production wastewater treatment plant and the receiving river.
The study identified multiple tetracycline resistance genes (tet(A), tet(W), tet(C), tet(J), tet(L), tet(D), tet(Y), and tet(K)) in environmental bacteria from an oxytetracycline production wastewater treatment plant and the receiving river, highlighting the widespread dissemination of these genes in aquatic environments exposed to high levels of antibiotic residues.
Utility of antibiotic resistance in chlamydial genetics, recombination & transformation
The paper discusses various antibiotic resistance mechanisms in Chlamydiae, including tetracycline resistance via the tet(C) gene, rifampin resistance through rpoB mutations, fluoroquinolone resistance involving gyrA, aminoglycoside resistance linked to 16S rRNA mutations, macrolide resistance due to rplD mutations, and sulfonamide/trimehoprim resistance via folP and folA mutations.
Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes.
The study identifies several antimicrobial resistance genes in the plasmid of the adherent-invasive E. coli strain NRG857c, including blaTEM, tetC, tetA, catI, dhfrI, sulII, and sulI, which confer resistance to ampicillin, tetracycline, chloramphenicol, and sulfonamides.
Antimicrobial resistance, virulence-associated genes, and pulsed-field gel electrophoresis profiles of Salmonella enterica subsp. enterica serovar Typhimurium isolated from piglets with diarrhea in Korea.
The study identified multiple antimicrobial resistance genes in Salmonella enterica subsp. enterica serovar Typhimurium isolates from piglets with diarrhea in Korea, including bla PSE, bla TEM, cat1, cat2, floR, strA, strB, aadA, sulI, sulII, tetA, tetC, and tetG.
Distribution and characterization of ampicillin- and tetracycline-resistant Escherichia coli from feedlot cattle fed subtherapeutic antimicrobials.
The study identified the tetracycline resistance gene tet(B) and the ampicillin resistance gene tem1-like in Escherichia coli isolates from feedlot cattle. These genes were found to confer resistance to tetracycline and ampicillin, respectively.
Functional metagenomics reveals previously unrecognized diversity of antibiotic resistance genes in gulls.
The study identified numerous antibiotic resistance (AR) genes in gulls, including both known and previously undescribed ones. It highlights the significant diversity of AR genes in gulls, emphasizing their potential role in spreading resistance genes between human and environmental habitats.
Long-term exposure to antibiotics has caused accumulation of resistance determinants in the gut microbiota of honeybees.
The study identifies eight tetracycline resistance genes (tetB, tetC, tetD, tetH, tetL, tetY, tetM, and tetW) in the gut microbiota of honeybees, highlighting the accumulation of resistance determinants due to long-term antibiotic exposure in beekeeping practices.
Comparative genomic analysis and virulence differences in closely related salmonella enterica serotype heidelberg isolates from humans, retail meats, and animals.
The study identified several AMR genes and mutations in Salmonella enterica serotype Heidelberg isolates, including bla, aac(6')-Ib, tet(M), qnrS1, and erm(B). Mutations in genes such as SEEHRA37_03221, SEEHRA37_24108, and others were associated with resistance traits.
A comprehensive insight into tetracycline resistant bacteria and antibiotic resistance genes in activated sludge using next-generation sequencing.
The study identifies several tetracycline resistance genes (tetA, tetC, and tetG) in activated sludge exposed to tetracycline, highlighting their increased abundance and diversity under tetracycline stress. It also reveals the presence of novel tetracycline-resistant bacteria genera.
Whole-genome sequence of Chryseobacterium oranimense, a colistin-resistant bacterium isolated from a cystic fibrosis patient in France.
The study identified multiple AMR genes and mutations in Chryseobacterium oranimense G311, a colistin-resistant bacterium isolated from a cystic fibrosis patient. These include various beta-lactamases, aminoglycoside modifying enzymes, tetracycline resistance genes, MLS resistance genes, phenicol resistance genes, glycopeptide resistance genes, fluoroquinolone resistance genes, sulfonamide resistance genes, rifampin resistance genes, and multidrug efflux pumps. Additionally, mutations in pmrA, pmrB, and lpxA were found to contribute to colistin resistance.
Prevalence of virulence determinants and antimicrobial resistance among commensal Escherichia coli derived from dairy and beef cattle.
The study identified several antimicrobial resistance genes in commensal E. coli from dairy and beef cattle, including blaTEM, blaSHV, aadA1, tetA, tetB, and tetC. These genes conferred resistance to ampicillin, streptomycin, and tetracycline. Dairy cattle isolates showed higher resistance rates compared to beef cattle.
Prevalence of Antimicrobial Resistance and Transfer of Tetracycline Resistance Genes in Escherichia coli Isolates from Beef Cattle.
The study identified tet(A), tet(B), and tet(C) as the predominant tetracycline resistance genes in E. coli isolates from beef cattle, with tet(B) showing higher MIC values compared to tet(A).
Sampling and Pooling Methods for Capturing Herd Level Antibiotic Resistance in Swine Feces using qPCR and CFU Approaches.
The study identified several antibiotic resistance genes in swine fecal samples using qPCR, including tetracycline resistance genes (tet(A), tet(B), tet(C), tet(M), tet(O), tet(W)), erythromycin resistance genes (ermB, ermF), sulfonamide resistance genes (sulI, sulII), beta-lactam resistance genes (blaCTX-M-1 group, blaCMY-2, blaSHV family), and glycopeptide resistance gene (vanA).
Identification and antimicrobial resistance prevalence of pathogenic Escherichia coli strains from treated wastewater effluents in Eastern Cape, South Africa.
The study identified several AMR genes in E. coli isolates from wastewater effluents, including strA, aadA, catI, cmlA1, blaTEM, and various tetracycline resistance genes (tetA, tetB, tetC, tetD, tetK, tetM). These genes conferred resistance to multiple antibiotics such as streptomycin, gentamicin, chloramphenicol, ampicillin, and tetracycline.
Tetracycline Susceptibility in Chlamydia suis Pig Isolates.
All C. suis isolates from the Italian pig herd carried the tet(C) gene and exhibited tetracycline resistance with MIC values ranging from 0.5 to 4 μg/mL. The study confirmed the presence of tet(C) and tetR(C) transcripts in all isolates under both in vitro conditions.
Chlamydial Antibiotic Resistance and Treatment Failure in Veterinary and Human Medicine.
The study discusses the emergence of tetracycline-resistant Chlamydia suis strains carrying the tetC gene, which encodes a tetracycline efflux pump. It highlights the potential for horizontal gene transfer of antibiotic resistance genes between chlamydial species and the challenges in treating chlamydial infections due to various resistance mechanisms.
ICEApl1, an Integrative Conjugative Element Related to ICEHin1056, Identified in the Pig Pathogen Actinobacillus pleuropneumoniae.
The study identifies ICEApl1, an integrative conjugative element in Actinobacillus pleuropneumoniae, which contains tetracycline resistance genes tetB, tetC, tetD, and tetR. This element confers tetracycline resistance and was found in serovar 8 isolates.
Whole-Genome Sequencing for Detecting Antimicrobial Resistance in Nontyphoidal Salmonella.
The study identified 65 unique resistance genes in nontyphoidal Salmonella, including bla CTX-M1 and bla SHV2a, which were first reported in retail meat isolates in the United States. The research highlights the effectiveness of whole-genome sequencing in detecting antimicrobial resistance genes and correlating them with phenotypic resistance.
Tetracycline Selective Pressure and Homologous Recombination Shape the Evolution of Chlamydia suis: A Recently Identified Zoonotic Pathogen.
The study identifies the acquisition of a tetracycline resistance cassette containing the tet(C) gene in Chlamydia suis strains through horizontal gene transfer. This cassette was found in all but one of the sequenced strains and is associated with tetracycline resistance.
Selective Pressure Promotes Tetracycline Resistance of Chlamydia Suis in Fattening Pigs.
The study identifies the tetracycline resistance gene tet(C) in Chlamydia suis and shows that its presence correlates with tetracycline resistance, although not all tet(C)-positive isolates exhibit resistance. The research highlights the impact of antibiotic usage on the development of resistance in porcine populations.
Epidemiological, molecular characterization and antibiotic resistance of Salmonella enterica serovars isolated from chicken farms in Egypt.
The study identified various AMR genes in Salmonella enterica serovars isolated from chicken farms in Egypt, including blaTEM, aadA2, floR, cat1, sul1, sul3, tetC, tetA, and intI, which confer resistance to ampicillin, streptomycin, chloramphenicol, sulfamethoxazole, tetracycline, and multiple antibiotics.
Prevalence, virulence potential, and pulsed-field gel electrophoresis profiling of Shiga toxin-producing Escherichia coli strains from cattle.
The study identified various antimicrobial resistance genes in STEC isolates from cattle, including ampC, blaTEM, tetE, tetB, and tetC, which confer resistance to beta-lactams and tetracyclines. These findings highlight the importance of monitoring antimicrobial resistance in STEC strains.
Asymptomatic infections with highly polymorphic Chlamydia suis are ubiquitous in pigs.
The study identifies the presence of tetracycline resistance gene tet(C) and tetracycline repressor gene tetR(C) in Chlamydia suis strains, indicating tetracycline resistance mechanisms in these strains.
Subtype-Specific Selection for Resistance to Fluoroquinolones but Not to Tetracyclines Is Evident in Campylobacter jejuni Isolates from Beef Cattle in Confined Feeding Operations in Southern Alberta, Canada.
The study identifies tetO as the primary tetracycline resistance gene in Campylobacter jejuni isolates from beef cattle and highlights gyrA mutations, particularly Thr86Ile, as a major cause of fluoroquinolone resistance.
Antimicrobial Resistance in Chlamydiales, Rickettsia, Coxiella, and Other Intracellular Pathogens.
The study identifies the tetracycline resistance gene tet(C) in Chlamydia suis, which encodes a tetracycline efflux pump. This gene is responsible for tetracycline resistance in C. suis strains, highlighting the emergence of antibiotic resistance in intracellular pathogens.
Characterization of antimicrobial resistance genes in Haemophilus parasuis isolated from pigs in China.
The study identified multiple antimicrobial resistance genes in Haemophilus parasuis isolates from pigs in China, including blaTEM-1, blaROB-1, ermB, ermA, flor, catl, tetB, tetC, rmtB, rmtD, aadA1, aac(3′)-IIc, sul1, and sul2. Additionally, mutations in the gyrA and parC genes were associated with fluoroquinolone resistance.
High genomic diversity of multi-drug resistant wastewater Escherichia coli.
The study identifies several known and novel resistance genes in wastewater-derived E. coli, highlighting the high genomic diversity and the presence of genes associated with resistance to various antibiotics.
Antimicrobial Resistance in Escherichia coli.
The paper discusses the characterization of various antimicrobial resistance genes in Escherichia coli, including extended-spectrum beta-lactamases (ESBLs), AmpC cephalosporinases, carbapenemases, plasmid-mediated quinolone resistance (PMQR) genes, aminoglycoside-modifying enzymes, fosfomycin resistance genes, and tetracycline resistance genes. These genes confer resistance to multiple classes of antibiotics, highlighting the complex nature of antimicrobial resistance in E. coli.
Antibiotic resistance gene dynamics in the gut microbiota following amoxicillin-clavulanic acid treatment
The study identified several AMR genes, including aminoglycoside resistance genes (ksgA, strA, strB), beta-lactam resistance genes (blaCARB-4, blaCMY-1, blaCMY-2, blaCTX-M-1, blaCTX-M-12, blaDHA-1, blaOXA-1, blaSHV-1, blaSHV-37, blaSHV-3, blaTEM-1A, blaTEM-1B), and tetracycline resistance genes (tetA, tetB, tetC, tetK, tetL), that were enriched in the gut microbiota of healthy adults following amoxicillin-clavulanic acid treatment.
Occurrence and Distribution of Tetracycline Antibiotics and Resistance Genes in Longshore Sediments of the Three Gorges Reservoir, China.
The study identified the presence of tetracycline resistance genes tet(A), tet(C), and tet(M) in longshore sediments of the Three Gorges Reservoir, with varying abundances across different zones and seasons.
Draft Genome Sequence of an Enterococcus faecalis Strain (24FS) That Was Isolated from Healthy Infant Feces and Exhibits High Antibacterial Activity, Multiple-Antibiotic Resistance, and Multiple Virulence Factors.
The study reports the draft genome sequence of Enterococcus faecalis 24FS, highlighting its multiple-antibiotic resistance traits, including resistance to chloramphenicol, tetracycline, erythromycin, aminoglycosides, fluoroquinolones, trimethoprim, streptothricin, and streptomycin, along with potential virulence factors.
Determining antimicrobial susceptibility in Salmonella enterica serovar Typhimurium through whole genome sequencing: a comparison against multiple phenotypic susceptibility testing methods.
The study identified various AMR genes and mutations in Salmonella enterica serovar Typhimurium, including aadA, strAB, blaTEM, blaCARB, floR, cmlA1, catA1, qnrB19, sul1, sul2, sul3, dfrA1, dfrA12, dfrA14, tetA, tetB, tetC, tetG, and mutations in gyrA. These genes and mutations were validated through whole genome sequencing and phenotypic ASTs.
First Report of Coexistence of Three Different MDR Plasmids, and That of Occurrence of IMP-Encoding Plasmid in Leclercia adecarboxylata.
The study reports the first identification of three different multidrug-resistant (MDR) plasmids in a single clinical isolate of Leclercia adecarboxylata, including the blaIMP-8 gene encoded on an IMP-encoding plasmid. These plasmids harbor various AMR genes such as blaIMP-8, aacC2, aadA2, mph(A), sul1, qacED1, mer, chrA, dfrA12, tmrB, catA1, catB8, tet(C), blaCTX-M-9, and blaTEM-1.
Evolution of Antibiotic Resistance and the Relationship between the Antibiotic Resistance Genes and Microbial Compositions under Long-Term Exposure to Tetracycline and Sulfamethoxazole.
The study identified the expansion of tetracycline and sulfonamide resistance genes, particularly tetC and sul1, under long-term exposure to tetracycline and sulfamethoxazole in wastewater treatment systems.
Metagenomic identification of severe pneumonia pathogens in mechanically-ventilated patients: a feasibility and clinical validity study.
The study identified several AMR genes using Nanopore sequencing, including mecA, blaTEM-4, blaTEM-112, blaTEM-157, blaACT-5, oqxB, tetC, ermA, erm (33), tet38, ant(4′)-lb, tetK, tetQ, sul1, dfrA, acrF, parE, mfd, mphA, aadA5, vgaC, blaACT-5, blaACT-14, mefA, mel, tetX, tetM, isaC, and aadA5, which conferred resistance to various antibiotics such as methicillin, ticarcillin, ceftazidime, erythromycin, clindamycin, tetracycline, trimethoprim-sulfamethoxazole, ciprofloxacin, and levofloxacin.
Molecular Detection Of Multidrug-Resistant Salmonella Isolated From Livestock Production Systems In South Africa.
The study identified multiple multidrug-resistant Salmonella isolates from livestock in South Africa, highlighting the presence of resistance genes such as blaTEM-1, blaCMY-2, tetA, tetC, sul2, and dfrA7.
Use of whole genome sequencing of commensal Escherichia coli in pigs for antimicrobial resistance surveillance, United Kingdom, 2018.
The study analyzed 515 E. coli isolates from pigs using whole genome sequencing to identify AMR genes and mutations. Key findings include the prevalence of blaTEM-1b, tet(A), and tetA(B) genes, along with various mutations in gyrA, parC, and parE that confer resistance to fluoroquinolones. The study highlights the effectiveness of WGS in predicting AMR phenotypes with high concordance to MIC results.
Prevalence and characteristics of multidrug-resistant mcr-1-positive Escherichia coli isolates from broiler chickens in Tai'an, China.
The study identified mcr-1 as the primary cause of colistin resistance in E. coli isolates from broiler chickens in Tai'an, China, with high prevalence of multidrug resistance involving genes like bla TEM, bla CTX-M, aphA3, tetA, tetB, tetC, sul1, and sul2.
DNA extraction of microbial DNA directly from infected tissue: an optimized protocol for use in nanopore sequencing.
The study presents an optimized DNA extraction protocol for improving the identification of Staphylococcus aureus and its antibiotic resistance genes from infected tissue using nanopore sequencing. The modified protocol significantly reduced human DNA content, enhancing the sensitivity of metagenomic sequencing. Several antibiotic resistance genes, including arlS, sav1866, norA, mepA, and tetC, were identified in S. aureus isolates from patients with orthopedic implant-related infections.
Whole Genome Sequencing and Characteristics of mcr-1-Harboring Plasmids of Porcine Escherichia coli Isolates Belonging to the High-Risk Clone O25b:H4-ST131 Clade B.
The study identified the mcr-1.1 gene in five porcine E. coli isolates, which confers resistance to colistin. The gene was found on various plasmids, including IncF, IncX4, and IncHI2, highlighting the role of mobile genetic elements in the spread of colistin resistance.
Co-occurrence of mcr-1, mcr-3, mcr-7 and clinically relevant antimicrobial resistance genes in environmental and fecal samples.
The study identified the co-occurrence of mcr-1, mcr-3, mcr-7.1, and various clinically relevant antimicrobial resistance genes in environmental and fecal samples from a Brazilian zoo, highlighting the potential reservoir of these genes in zoological environments.
Prevalence and distribution of antimicrobial resistance determinants of Escherichia coli isolates obtained from meat in South Africa.
The study identified several AMR genes in E. coli isolates from meat in South Africa, including aadA, strA, aph(3)-Ia, aph(3)-IIa, aac(3)-IIa, blaTEM, blaZ, ampC, cat1, cat2, cmlA1, sul1, sul2, tetA, tetB, tetC, tetD, and tetM, which confer resistance to various antibiotics such as streptomycin, kanamycin, neomycin, gentamicin, amoxicillin, ampicillin, chloramphenicol, cotrimoxazole, and tetracycline.
Comparative analysis of multidrug resistance plasmids and genetic background of CTX-M-producing Escherichia coli recovered from captive wild animals.
The study identifies multiple AMR genes and mutations in MDR E. coli strains from captive wild animals, highlighting the presence of CTX-M-8 and CTX-M-65 beta-lactamases, along with various other resistance mechanisms such as aminoglycoside, tetracycline, and fluoroquinolone resistance genes, as well as mutations in quinolone resistance-determining regions.
Tracking Antimicrobial Resistance Determinants in Diarrheal Pathogens: A Cross-Institutional Pilot Study.
The study identified 55 different antimicrobial resistance determinants in diarrheal pathogens, highlighting the presence of genes conferring resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, macrolides, tetracyclines, phenicols, sulfonamides, and others. Notably, carbapenemase genes like bla OXA-48 and bla NDM were detected in certain isolates, indicating emerging resistance concerns.
Emergence of NDM-5-Producing Carbapenem-Resistant Klebsiella pneumoniae and SIM-Producing Hypervirulent Klebsiella pneumoniae Isolated from Aseptic Body Fluid in a Large Tertiary Hospital, 2017-2018: Genetic Traits of blaNDM-Like and blaSIM-Like Genes as Determined by NGS.
The study identified NDM-5-producing CRKP and SIM-producing hvKP strains, highlighting the emergence of novel resistance mechanisms and the effectiveness of tigecycline-carbapenem combinations in treating these infections.
Pyrolyzed biowastes deactivated potentially toxic metals and eliminated antibiotic resistant genes for healthy vegetable production.
The study found that pyrolysis of biowastes effectively reduced the abundance of antibiotic resistance genes (ARGs) such as tetracycline resistance genes (tetC, tetG, tetM, tetO, tetW), sulfonamide resistance genes (sul1, sul2), and class 1 integron-integrase gene (intI1) in swine manure and sewage sludge.
Genotyping and molecular characterization of antimicrobial resistance in thermophilic Campylobacter isolated from poultry breeders and their progeny in Eastern Spain.
The study identified qnrS, blaTEM, tetC, and ermB genes associated with resistance to quinolones, beta-lactams, tetracyclines, and macrolides in Campylobacter isolates from poultry breeders and their progeny.
Biological Characteristics and Genetic Analysis of a Highly Pathogenic Proteus Mirabilis Strain Isolated From Dogs in China.
The study identified 18 antibiotic resistance genes in the multidrug-resistant Proteus mirabilis strain CC15031, including genes conferring resistance to various antibiotics such as chloramphenicol, tetracycline, aminoglycosides, beta-lactams, sulfonamides, and others.
Collateral sensitivity associated with antibiotic resistance plasmids.
The study identifies several AMR genes carried by clinically relevant plasmids, including blaOXA-48, qnrS1, blaSHV-12, aac(6')-Ib3, blaVEB-9, qnrVC-1, sul1, tetA', tetC, dfrA1, dfrA23, blaVIM-1, aadA1, qacEΔ1, blaBEL-1, blaGES-5, blaIMP-8, and blaFOX-8. These genes confer resistance to various antibiotics, and the study highlights the collateral sensitivity associated with the acquisition of these plasmids.
Antibiotic Resistance and Phylogeny of Pseudomonas spp. Isolated over Three Decades from Chicken Meat in the Norwegian Food Chain.
The study identified several AMR genes and mutations in Pseudomonas spp. isolated from chicken meat in Norway, including beta-lactamases, efflux pumps, and genes involved in resistance to aminoglycosides, fluoroquinolones, and colistin.
On-Farm Anaerobic Digestion of Dairy Manure Reduces the Abundance of Antibiotic Resistance-Associated Gene Targets and the Potential for Plasmid Transfer.
The study found that anaerobic digestion of dairy manure significantly reduced the abundance of antibiotic resistance genes, including various ESBL genes such as bla CTX-M-1, bla CTX-M-14, bla CTX-M-15, bla CTX-M-27, bla CTX-M-55, and bla PER-1, as well as other resistance genes like aac(6')-Ib-cr, aph(3')-Ib, aph(6)-Id, bla OXA-1, catB4, dfrA1, floR, lnu(G), sul2, aadA2, mph(E), msr(E), tet(C), tet(E), and tet(X).
Prevalence and mechanisms of antibiotic resistance in Escherichia coli isolated from mastitic dairy cattle in Canada.
The study identified several AMR genes in E. coli isolates from bovine mastitis, including beta-lactamases (blaTEM-1, blaCARB-3, blaCMY-59), tetracycline resistance genes (tetA, tetB, tetC), aminoglycoside resistance genes (aph(3')-Ia, aph(3'')-Ib, aph(6)-Id, aadA2), and multidrug efflux pump genes (acrA, acrB, acrD, tolC, baeR, emrA, emrB).
Antibiotic Susceptibility Profile and Tetracycline Resistance Genes Detection in Salmonella spp. Strains Isolated from Animals and Food.
The study identified multiple tetracycline resistance genes (tet(A), tet(B), tet(C), tet(D), tet(E), and tet(G)) in Salmonella spp. strains isolated from animals and food, highlighting the prevalence of these genes and their potential role in the spread of antibiotic resistance.
Genetic Diversity of Multidrug-Resistant Pseudomonas aeruginosa Isolates Carrying bla (VIM-2) and bla (KPC-2) Genes That Spread on Different Genetic Environment in Colombia.
The study identifies bla(VIM-2) and bla(KPC-2) genes in multidrug-resistant Pseudomonas aeruginosa isolates from Colombia, highlighting their diverse genetic environments and mechanisms of resistance.
Discerning the Antimicrobial Resistance, Virulence, and Phylogenetic Relatedness of Salmonella Isolates Across the Human, Poultry, and Food Materials Sources in Malaysia.
The study identified several AMR genes in Salmonella Enteritidis isolates from Malaysia, including aac(6')-ly, blaCMY-2, blaTEM-1, blaTEM-33, blaTEM-4, dfrA14, dfrA15, floR, qnrS1, qnrD1, sul1, sul2, strA, strB, tetA, and tetC. These genes conferred resistance to various antibiotics such as gentamicin, ampicillin, chloramphenicol, ciprofloxacin, sulfamethazine/trimethoprim, and tetracycline.
Insight Into Whole Genome of Aeromonas veronii Isolated From Freshwater Fish by Resistome Analysis Reveal Extensively Antibiotic Resistant Traits.
The study identified 17 AMR genes in Aeromonas veronii isolates from tilapia, highlighting extensive antibiotic resistance traits, including resistance to beta-lactams, aminoglycosides, tetracyclines, and others.
Monitoring the Microevolution of Salmonella enterica in Healthy Dairy Cattle Populations at the Individual Farm Level Using Whole-Genome Sequencing.
The study identified several AMR genes, including bla CMY-2, floR, sul2, and tetA, in Salmonella enterica isolates from dairy cattle. These genes confer resistance to various antibiotics such as cephalosporins, florfenicol, sulfamethoxazole-trimethoprim, and tetracycline.
High prevalence of multiple antibiotic resistance in clinical E. coli isolates from Bangladesh and prediction of molecular resistance determinants using WGS of an XDR isolate.
The study identified multiple antibiotic resistance genes, including blaNDM, blaOXA-47, ampC, tetC, blaCTX-M-15, and blaTEM, in clinical E. coli isolates from Bangladesh, highlighting the high prevalence of multidrug-resistant strains.
Impact of Antibiotic Therapies on Resistance Genes Dynamic and Composition of the Animal Gut Microbiota.
The study examined the impact of antibiotic therapies on the dynamics and composition of resistance genes in the animal gut microbiota, identifying several AMR genes such as blaTEM, tetA, strA, strB, intI1, tetM, mel, floR, mcr-2, oqx B, tetC, tetG, tetO, tetW, tetX, ermB, ermF, sul1, sul2, and others, which were experimentally validated in Escherichia coli.
Oxytetracycline and Streptomycin Resistance Genes in Xanthomonas arboricola pv. pruni, the Causal Agent of Bacterial Spot in Peach.
The study identifies tetC, tetR, and strAB as the genes responsible for oxytetracycline and streptomycin resistance in Xanthomonas arboricola pv. pruni. These genes are located on a multidrug-resistant plasmid and can be transferred to other bacterial species via conjugation.
Emergence of Carbapenem-Resistant ST244, ST292, and ST2446 Pseudomonas aeruginosa Clones in Burn Patients in Yunnan Province.
Bacterial diversity and the antimicrobial resistome in the southwestern highlands of Saudi Arabia.
The study identified 102 antimicrobial resistance genes (ARGs) in the soil microbiota of the southwestern highlands of Saudi Arabia, primarily associated with multidrug resistance, macrolide, tetracycline, glycopeptide, bacitracin, and beta-lactam antibiotic resistance. qPCR confirmed the detection of 18 clinically important ARGs.
Analysis of Salmonella enterica Isolated from a Mixed-Use Watershed in Georgia, USA: Antimicrobial Resistance, Serotype Diversity, and Genetic Relatedness to Human Isolates.
The study identified multiple antimicrobial resistance genes in Salmonella enterica isolates from a mixed-use watershed in Georgia, USA, including bla CMY-2, aadA2, strA, strB, sul1, sul2, tetA, tetC, floR, and dfrA12, which conferred resistance to various antibiotics such as ceftiofur, ceftriaxone, streptomycin, sulfisoxazole, tetracycline, chloramphenicol, and trimethoprim.
Occurrence of antibiotics and bacterial resistance genes in wastewater: resistance mechanisms and antimicrobial resistance control approaches.
The study identifies several AMR genes and mutations associated with resistance to various antibiotics in wastewater environments, highlighting the role of these genes in the spread of antimicrobial resistance.
Genomic diversity of genus Limosilactobacillus.
The study identified 18 AMR genes in Limosilactobacillus species, primarily in L. reuteri from animal sources, including tetracycline, aminoglycoside, macrolide-lincosamide-streptogramin, and lincomycin resistance genes.
Within-farm dynamics of ESBL-producing Escherichia coli in dairy cattle: Resistance profiles and molecular characterization by long-read whole-genome sequencing.
The study identified multiple ESBL-encoding genes, including bla CTX-M-1, bla CTX-M-14, bla CTX-M-15, bla CTX-M-27, bla CTX-M-32, and bla SHV-12, as well as carbapenemase gene bla NDM-1, in ESBL-producing E. coli isolates from dairy cattle farms. These genes were associated with resistance to various beta-lactam antibiotics. Additionally, several other AMR genes such as aadA2, ant(3")-Ia, aph(3')-Ia, dfrA12, sul3, cmlA1, and others were identified, contributing to resistance against aminoglycosides, trimethoprim, sulfamethoxazole, and chloramphenicol. Mutations in gyrA, parC, and parE were linked to fluoroquinolone resistance.
Antimicrobial Resistance: Mechanisms, Spread, and Control
The paper discusses the prevalence and mechanisms of antimicrobial resistance, focusing on tetracycline resistance genes such as tetA, tetB, tetC, tetD, tetE, tetI, and tetY in Escherichia coli. These genes are associated with efflux mechanisms that contribute to resistance against tetracycline.
Hitherto-Unnoticed Self-Transmissible Plasmids Widely Distributed among Different Environments in Japan.
The study identified new subgroups of IncP/P-1 and PromA plasmids, including antibiotic resistance genes such as blaIMP-1, blaKPC-2, mcr-1, and various tetracycline and aminoglycoside resistance genes.
Molecular characterization and biofilm-formation analysis of Listeria monocytogenes, Salmonella spp., and Escherichia coli isolated from Brazilian swine slaughterhouses.
The study identified various antimicrobial resistance genes in E. coli and Salmonella Typhi isolates from Brazilian swine slaughterhouses, including ampC, blaSHV, cat1, clmA, MCR-1, MCR-3, tet(A), tet(B), tet(C), tet(M), and sulI. These genes conferred resistance to multiple antibiotics such as ampicillin, amoxicillin, chloramphenicol, tetracycline, doxycycline, colistin, and sulfonamide.
Resistance Phenotype and Molecular Epidemiology of Carbapenem-Resistant Klebsiella pneumoniae Isolated from Nanjing Children's Hospital in Jiangsu Province, China.
The study identified several carbapenemase genes, including blaKPC-2, blaNDM-1, blaNDM-5, blaIMP-8, and blaOXA-181, as well as other resistance genes such as blaCTX-M, blaSHV-2, APH(3)-IB, APH(6)-ID, FosA5, tetC, qnrB1, and tetA, contributing to multidrug resistance in CRKP strains isolated from children in Nanjing, China.
Molecular Typing Reveals Environmental Dispersion of Antibiotic-Resistant Enterococci under Anthropogenic Pressure.
The study identified multiple antibiotic resistance genes in Enterococcus isolates from various aquatic environments, highlighting the role of anthropogenic pressure in the spread of antibiotic-resistant enterococci.
Genome-wide analysis reveals the emergence of multidrug resistant Stenotrophomonas acidaminiphila strain SINDOREI isolated from a patient with sepsis.
The study identifies multiple antibiotic resistance genes in the multidrug-resistant Stenotrophomonas acidaminiphila strain SINDOREI, including sul1, sul2, qnr, GES-1, aadA3, qacL, cmlA5, and tetC, which confer resistance to trimethoprim/sulfamethoxazole, fluoroquinolone, beta-lactam, aminoglycoside, disinfecting agents, phenicol, and tetracycline.
Virulence Determinants and Methicillin Resistance in Biofilm-Forming Staphylococcus aureus from Various Food Sources in Bangladesh.
The study identified the methicillin resistance gene mecA, beta-lactam resistance gene blaZ, and tetracycline resistance genes tetA and tetC in biofilm-forming Staphylococcus aureus isolates from food sources in Bangladesh.
Enhance antibiotic resistance and human health risks in aerosols during the COVID-19 pandemic.
The study identified increased abundances of antibiotic resistance genes (ARGs) in aerosols during the COVID-19 pandemic, particularly sulfonamide (sul1, sul2), tetracycline (tetA, tetC), and beta-lactam (ampC) resistance genes. These genes were associated with heightened antibiotic resistance in airborne bacteria, contributing to elevated human health risks.
Correlations among Antibiotic Resistance Genes, Mobile Genetic Elements and Microbial Communities in Municipal Sewage Treatment Plants Revealed by High-Throughput Sequencing.
The study identifies various tetracycline resistance genes (tetC, tetE, tetG, tetM, tetO, tetQ, tetW, tetX), sulfonamide resistance gene (sulI), aminoglycoside resistance genes (ant(2')-Ia, ant(3')-Ia, aph(6')-Id, aph(33')-Ib, aac(6')-Ib), beta-lactam resistance genes (blaGES, blaVEB), chloramphenicol resistance gene (catB3), MLS resistance genes (ereA, ermB), and multidrug resistance genes (acrB, mexB, mexF) in municipal sewage treatment plants, highlighting their association with mobile genetic elements and microbial communities.
A survey on antimicrobial resistance genes of frequently used probiotic bacteria, 1901 to 2022.
The study identified various antimicrobial resistance genes in probiotic bacteria, highlighting the presence of mobile genetic elements and the potential for horizontal gene transfer.
Distribution analysis of tetracycline resistance genes in Escherichia coli isolated from floor surface and effluent of pig slaughterhouses in Banten Province, Indonesia.
The study identified the distribution of tetracycline resistance genes (tetA, tetB, tetC, tetE, tetM, tetO, and tetX) in Escherichia coli isolates from pig slaughterhouses in Banten Province, Indonesia. The tetO gene was the most dominant in floor surface samples, while tetA was dominant in effluent samples.
Antibiotic Resistance Profiles and ARG Detection from Isolated Bacteria in a Culture-Dependent Study at the Codfish Industry Level.
The study identified various antibiotic resistance genes in bacteria isolated from codfish products and environmental samples, highlighting the presence of tetracycline, clindamycin, and oxacillin resistance genes in Staphylococcus spp., as well as beta-lactam and carbapenem resistance genes in Gram-negative bacteria.
Antibiotic-Resistant Desulfovibrio Produces H(2)S from Supplements for Animal Farming.
The study identifies multiple antibiotic resistance genes in Desulfovibrio vulgaris L2, including beta-lactamases, aminoglycoside modifying enzymes, tetracycline resistance genes, and mercury resistance genes, highlighting its potential role in spreading antibiotic resistance in agricultural environments.
Multidrug-resistant Campylobacter jejuni, Campylobacter coli and Campylobacter lari isolated from asymptomatic school-going children in Kibera slum, Kenya.
The study identified multidrug-resistant strains of Campylobacter jejuni, Campylobacter coli, and Campylobacter lari in asymptomatic schoolchildren in Kenya, with high resistance rates to tetracycline, ciprofloxacin, nalidixic acid, and erythromycin. The most prevalent tetracycline resistance genes were tet(A), tet(O), and tet(C).
ARGs Detection in Listeria Monocytogenes Strains Isolated from the Atlantic Salmon (Salmo salar) Food Industry: A Retrospective Study.
The study identified various AMR genes in L. monocytogenes strains from Atlantic salmon, including tetracycline resistance genes (tetC, tetD, tetK, tetL, tetS), aminoglycoside resistance genes (aadA, strA, aacC2, aphA1, aphA2), macrolide resistance genes (cmlA1, catI, catII), and oxazolidinone resistance genes (cfr, optrA, poxtA).
Food risk associated with vegetable consumption, exposure to antimicrobial-resistant strains and pesticide residues.
The study identified several antimicrobial resistance genes in AMR strains isolated from vegetables, including blaTEM, tetA, tetW, tetC, tetD, tetB, qnrS, and sulI. These genes conferred resistance to various antibiotics such as ampicillin, amoxicillin/clavulanic acid, tetracycline, ciprofloxacin, nalidixic acid, and trimethoprim/sulfamethoxazole.
On the use of antibiotics to control plant pathogenic bacteria: a genetic and genomic perspective.
The study identifies several AMR genes and mutations associated with streptomycin, kasugamycin, gentamicin, and oxytetracycline resistance in plant pathogenic bacteria, highlighting the role of Tn 5393 and other mobile genetic elements in the dissemination of these resistance traits.
Incidence and Genomic Background of Antibiotic Resistance in Food-Borne and Clinical Isolates of Salmonella enterica Serovar Derby from Spain.
The study identified several AMR genes, including aadA2, sul1, tet(A), tet(B), tet(C), blaTEM-1, and fosA7.3, in Salmonella enterica serovar Derby isolates from Spain. These genes were associated with resistance to streptomycin, sulfonamides, tetracycline, ampicillin, and fosfomycin. Additionally, a point mutation in the gyrA gene was linked to nalidixic acid resistance.
Genomic Characterization of Fecal Escherichia coli Isolates with Reduced Susceptibility to Beta-Lactam Antimicrobials from Wild Hogs and Coyotes.
The study identified beta-lactamase genes (blaCMY-2, blaCTX-M-55, blaCTX-M-27), tetracycline resistance genes (tetA, tetB, tetC), aminoglycoside resistance genes (aac(3)-IId, aadA5, ant(3")-Ia, aph(3')-Ia, aph(3")-lb, aph(6)-ld), sulfonamide resistance genes (sul1, sul2, sul3), amphenicol resistance gene (floR), trimethoprim resistance genes (dfrA1, dfrA17), and MLS resistance genes (Inu(F), erm(B), mph(A)) in E. coli isolates from coyotes and wild hogs. Additionally, chromosomal mutations in ampC, gyrA, parC, and parE were found to confer resistance to beta-lactam and quinolone antibiotics.
Drug Resistance, Characterization and Phylogenetic Discrepancy of Salmonella enterica Isolates from Distinct Sources.
The study identified several AMR genes in Salmonella enterica isolates from clinical and animal sources, including catA1, blaTEM, and tetC, which confer resistance to chloramphenicol, ampicillin, and tetracycline, respectively.
Detection of tetracycline resistance genes and their diversity in Escherichia coli isolated from pig farm waste in Banten province, Indonesia.
The study identified several tetracycline resistance genes, including tetA, tetB, tetC, tetM, tetO, and tetX, in Escherichia coli isolated from pig farm waste in Banten province, Indonesia. tetX and tetO were the most prevalent genes, with high frequencies detected in both solid waste and wastewater samples.
Prevalence of Escherichia coli isolated from oropharynx and trachea of clinically sick poultry and antimicrobial resistance pattern of the strains isolated.
The study identified the presence of tetA, tetB, and tetC genes in tetracycline-resistant E. coli isolates from poultry, highlighting the role of these genes in oxytetracycline resistance.
High-Pressure Processing-Impacts on the Virulence and Antibiotic Resistance of Listeria monocytogenes Isolated from Food and Food Processing Environments.
High-pressure processing (HPP) increases antibiotic resistance in Listeria monocytogenes isolates, particularly for tetracycline, with increased expression of tetA_1, tetA_3, and tetC genes.
Assessing the Effect of Oxytetracycline on the Selection of Resistant Escherichia coli in Treated and Untreated Broiler Chickens.
The study identified tet(A) and tet(C) genes as the most prevalent tetracycline resistance genes in E. coli isolates from treated and untreated broiler chickens, indicating that active efflux pumps are the primary resistance mechanism.
Serovars, Virulence and Antimicrobial Resistance Genes of Non-Typhoidal Salmonella Strains from Dairy Systems in Mexico.
Antibiotic resistance and virulence genes profile of Non typhodial Salmonella species isolated from poultry enteritis in India.
The study identified several antibiotic resistance genes including blaTEM, blaSHV, blaCTX-M, tet(A), tet(B), tet(C), sul1, sul2, and sul3 in multidrug-resistant Salmonella isolates from poultry enteritis in India.
Whole-genome sequencing-based antimicrobial resistance and shedding dynamics of Escherichia coli isolated from calves before and after antimicrobial group treatments.
The study identified several AMR genes and mutations in E. coli isolates from calves, including tetracycline resistance genes (Tet(A), Tet(B), Tet(C), Tet(M)), β-lactamases (TEM-1, TEM-35, OXA-1), florfenicol resistance gene FloR, and macrolide phosphotransferase Mph(B). Mutations in GyrA (D87N, D87Y, S83L) and ParC (S80I) were also associated with quinolone resistance.
Horizontal transfer characterization of ColV plasmids in bla(CTX-M)-bearing avian Escherichia coli.
The study characterizes the horizontal transfer of ColV plasmids in bla(CTX-M)-bearing avian E. coli, identifying multiple resistance genes and virulence factors associated with these plasmids.
Comparison of genotypic and phenotypic antimicrobial resistance profiles of Salmonella enterica isolates from poultry diagnostic specimens.
The study identified 31 AMR genes in 97 Salmonella enterica isolates from poultry, including aac(3)-IId, aac(3)-IVa, aac(3)-VIa, aac(6′)-Ib4, ant(2′′)-Ia, grdA, aph(3′)-Ia, aph(3′)-IIa, aadA1, aadA2, aadA7, aadA13, aph(3′)-Ib, aph(6)-Ic, aph(6)-Id, aph(4)-Ia, blaCMY-2, blaCTX-M-1, blaHER-3, blaTEM-1, floR, tetA, tetB, tetC, dfrA12, sul1, sul2, fosA7, qnrB19, ble, and mcr-9.
β-lactamase expression induces collateral sensitivity in Escherichia coli.
The study identifies that the expression of the β-lactamase gene blaOXA-48 induces collateral sensitivity to colistin and azithromycin in Escherichia coli.
Occurrence and genomic characterization of antimicrobial-resistant and potential pathogenic Escherichia coli from Italian artisanal food productions of animal origin.
The study identified multiple antimicrobial resistance (AMR) genes in Escherichia coli isolates from Italian artisanal food products, including beta-lactamases, aminoglycoside-modifying enzymes, trimethoprim resistance genes, macrolide resistance genes, quinolone resistance proteins, sulfonamide resistance proteins, and tetracycline resistance genes. These genes were primarily carried on plasmids and contributed to multidrug resistance.
Four novel Acinetobacter lwoffii strains isolated from the milk of cows in China with subclinical mastitis.
Four Acinetobacter lwoffii strains were isolated from the milk of cows with subclinical mastitis in China. These strains exhibited multidrug resistance and carried 17 resistance genes, including beta-lactamase, aminoglycoside-modifying, fluoroquinolone, tetracycline, sulfonamide, and chloramphenicol resistance genes.
Metagenomic Investigation of the Short-Term Temporal and Spatial Dynamics of the Bacterial Microbiome and the Resistome Downstream of a Wastewater Treatment Plant in the Iskar River in Bulgaria.
The study identified various antimicrobial resistance genes (ARGs) in the Iskar River downstream of a wastewater treatment plant (WWTP), including genes conferring resistance to macrolides, tetracyclines, beta-lactams, sulfonamides, and carbapenems. Notably, the carbapenemase genes bla OXA-58 and bla IMP-33-like were detected, which are typically associated with clinical settings.
Pathogenomics analysis of high-risk clone ST147 multidrug-resistant Klebsiella pneumoniae isolated from a patient in Egypt.
The study identifies multiple AMR genes in the MDR-KP isolate WSF99, including various beta-lactamases, carbapenemase, aminoglycoside modifying enzymes, fluoroquinolone resistance genes, and others, highlighting the complex resistance profile of this high-risk clone.
Genomic Insights of a Methicillin-Resistant Biofilm-Producing Staphylococcus aureus Strain Isolated From Food Handlers.
The study identified a multidrug-resistant Staphylococcus aureus strain (MTR_BAU_H1) isolated from food handlers in Bangladesh, carrying genes conferring resistance to methicillin (mecA), beta-lactams (blaZ), and tetracycline (tetC).
The synergy effect of matrine and berberine hydrochloride on treating colibacillosis caused by an avian highly pathogenic multidrug-resistant Escherichia coli.
The study identified multiple antibiotic resistance genes in a multidrug-resistant Escherichia coli strain, including blaTEM, ermA, ermB, aadA1, qnrS, qepA, oqxA, tetA, tetB, and tetC, which conferred resistance to various antibiotics such as beta-lactams, macrolides, aminoglycosides, quinolones, and tetracyclines. The combination of matrine and berberine hydrochloride showed synergistic antibacterial effects against this strain.
High-Pressure Processing Influences Antibiotic Resistance Gene Transfer in Listeria monocytogenes Isolated from Food and Processing Environments.
The study found that high-pressure processing (HPP) at 400 MPa increased the transfer frequency of fosX, tet_A1, tet_A3, and tetC genes in Listeria monocytogenes, which confer resistance to fosfomycin and tetracycline. The Lde gene, which confers ciprofloxacin resistance, was not transferred under any conditions.
Phenotypic and Genomic Characterization of ESBL- and AmpC-β-Lactamase-Producing Enterobacterales Isolates from Imported Healthy Reptiles.
The study identified multiple ESBL and AmpC β-lactamase genes, including bla CTX-M-15, bla CTX-M-55, bla CTX-M-3, bla CTX-M-27, bla CTX-M-65, bla SHV-12, bla SHV-42, bla DHA-1, bla CMY-2, bla CMY-3, bla CMY-46, bla CMY-101, bla ACT-16, bla CMH-like, and bla MIR-9, along with other AMR genes such as mcr-1, qnrS1, aac(6')-Ib-cr5, and various tetracycline, aminoglycoside, sulfonamide, chloramphenicol, macrolide, lincosamide, and rifampicin resistance genes in Enterobacterales isolates from imported healthy reptiles.
Plasmidome of Salmonella enterica serovar Infantis recovered from surface waters in a major agricultural region for leafy greens in California.
The study identified tetracycline resistance genes, including tetB, tetR, tetC, acrAB, and robA, in the IncI plasmid pRM18148 of Salmonella enterica serovar Infantis strains isolated from surface waters in California.
Dynamics of Salmonella Dublin infection and antimicrobial resistance in a dairy herd endemic to salmonellosis.
The study identified the presence of florR and cmlA1 genes responsible for phenicol resistance, and blaTEM-1A associated with beta-lactam resistance in Salmonella enterica serovar Dublin isolates from cattle in California.
The Difference a Year Can Make: How Antibiotic Resistance Mechanisms in Pseudomonas aeruginosa Have Changed in Northwestern Transylvania.
The study identified an increase in multidrug-resistant (MDR) and extensively drug-resistant (XDR) Pseudomonas aeruginosa isolates in Northwestern Transylvania, Romania, between 2022 and 2023. Key AMR genes included bla OXA-50, sul1, ermB, mexA, mexB, bla VIM-1, aac(6′)-II, ant(4′)-Ia, aac(3)-I, aac(6′)-Im, aph(2″)-Ib, tetA, tetC, tetK, qnrB, ermC, mphC, fosA, nfsA, nfsB, ampC, and TEM-1.
Genomic epidemiology and antimicrobial resistance of Morganella clinical isolates between 2016 and 2023.
The study identified several AMR genes in Morganella clinical isolates, including tet(B), sul1, catA2, sul2, floR, aadA1, and others, contributing to resistance against various antibiotics.
Unveiling the silent threat: A comprehensive review of Riemerella anatipestifer - From pathogenesis to drug resistance.
This review highlights the pathogenesis, virulence factors, and antibiotic resistance genes of Riemerella anatipestifer, emphasizing its significance in poultry farming and the need for further research on its resistance mechanisms.
Seasonal prevalence and antimicrobial resistance profiles in Enterococcus spp. identified from mussels farmed along the coasts of the Abruzzo region.
The study identified several antibiotic resistance genes in Enterococcus spp. isolated from mussels, including tetC, tetD, cfr, vanA, vanD, vatE, vatD, and qnrS, which confer resistance to tetracycline, linezolid, vancomycin, and fluoroquinolone.
Genomic features, antimicrobial resistance and pathogenicity assessment of Escherichia coli serotype O177:H51 strain JS01 isolated from a diseased chicken.
The study identified 64 AMR genes and 177 virulence factor genes in the E. coli strain JS01, highlighting its multidrug resistance and high pathogenicity.
Pan-genome analysis of the Enterobacter hormaechei complex highlights its genomic flexibility and pertinence as a multidrug resistant pathogen.
The study identifies a wide range of antibiotic resistance genes in the Enterobacter hormaechei complex, highlighting its multidrug-resistant nature and the role of mobile genetic elements in the dissemination of resistance.
Wild Birds as Drivers of Salmonella Braenderup and Multidrug Resistant Bacteria in Wetlands of Northern Italy.
The study identifies several AMR genes in bacterial isolates from wild aquatic birds in Northern Italy, including beta-lactamases (blaTEM, blaCMY-1, blaCMY-2, blaNDM, blaKPC), colistin resistance genes (mcr-2, mcr-3, mcr-4), tetracycline resistance genes (tetA, tetB, tetC, tetL, tetM, tetK), macrolide resistance genes (ermB, vatD, vgA, msrC), vancomycin resistance genes (vanC1, vanC2, vanM, vanG), sulfonamide resistance genes (sul1, sul2, sul3), aminoglycoside resistance genes (aac(3), aac(6')-Ib, aph(3')-Ia, armA, rmtB, rmtC, rmtF), and nitrofurantoin resistance genes (nfsA, nfsB).
Taxonomic and phenotypic characterization of a novel Providencia species: Providencia lanzhouensis sp. nov.
The study identifies Providencia lanzhouensis sp. nov., a novel species with multiple antimicrobial resistance genes, including aadA1, aadA2, aph(6)-Id, aph(3'')-Ib, aph(3')-Ia, sat2, sul2, ere(A), dfrA32, floR, tetC, and qnrD1, which confer resistance to aminoglycosides, streptomycin, sulfonamides, macrolides, trimethoprim, phenicols, tetracyclines, and quinolones.
Overlooked Enterobacterales as hosts of antimicrobial resistance in aquatic environments.
The study identified several AMR genes in environmental Enterobacterales isolates, including blaTEM-1, blaCTX-M, tetA, tetB, tetC, tetL, tetM, sul1, sul2, qnrS, ermB, and mefA, which conferred resistance to various antibiotics such as ampicillin, ceftazidime, cefepime, tetracycline, trimethoprim-sulfamethoxazole, ciprofloxacin, and erythromycin.
Global phylogeography and genomic characterization of bla(NDM-1)-positive clinical Proteus mirabilis isolates from China.
The study identifies blaNDM-1 as a key determinant of carbapenem resistance in Proteus mirabilis isolates from China, along with other resistance genes such as blaCTX-M-14, blaCTX-M-65, and blaTEM-1. It also characterizes the genomic context of blaNDM-1, including its integration into SGI1 and plasmid-borne elements.
Genetic diversity, virulence genes, antimicrobial resistance, and biofilm formation of Klebsiella pneumoniae isolated from bovine mastitis milk in South Korea.
The study identified several AMR genes in K. pneumoniae isolates from bovine mastitis milk in South Korea, including blaSHV, strA, strB, sulI, sulII, tetA, tetB, tetC, floR, dfrXII, blaTEM, blaCTX-M, and blaOXA, which confer resistance to various antibiotics such as ampicillin, gentamicin, trimethoprim/sulfamethoxazole, tetracycline, chloramphenicol, and others.
Global genomic and antimicrobial resistance profiling of Neisseria gonorrhoeae: Insights from whole genome sequencing and minimum inhibitory concentration analysis.
The study identifies key resistance mechanisms in Neisseria gonorrhoeae, including the widespread presence of efflux pump genes (norM, farB, mtrC, mtrA) and specific resistance genes such as bla TEM, tet(C), and erm(C). It highlights the increasing prevalence of antimicrobial resistance and the need for global surveillance and targeted interventions.
Acquisition of novel antibiotic resistance genes by the bacterial predator Bacteriovorax sp. As-1.
Bacteriovorax sp. As-1 exhibits resistance to multiple antibiotics, primarily due to mutations in the gyrA gene, specifically S90Y and G94R, which are associated with reduced fluoroquinolone susceptibility.
Emerging threat of antimicrobial resistance determinants and plasmid replicon types acquisition by Escherichia coli of poultry and other food-producing animal origin in China: local findings with global implications.
The study identifies multiple antimicrobial resistance genes in Escherichia coli from poultry and other food-producing animals in China, highlighting the prevalence of beta-lactamases, tetracycline resistance genes, aminoglycoside modifying enzymes, quinolone resistance genes, and sulfonamide resistance genes.
Antibiotic susceptibility pattern and resistance genes in Salmonella strains isolated from cattle.
The study identified tetracycline resistance genes tetA and tetC, and the beta-lactamase gene blaTEM-1 in Salmonella isolates from cattle, highlighting the prevalence of multidrug resistance.
Genomic diversity and antimicrobial resistance of Vibrio cholerae isolates from Africa: a PulseNet Africa initiative using nanopore sequencing to enhance genomic surveillance.
The study identified a high prevalence of trimethoprim resistance genes (dfrA1, dfrA15, dfrA31) and other resistance genes such as floR, strA, strB, varG, blaCARB-2, aadA1, aadA2, sul1, sul2, catB9, tet(C), tet(G), tet(59), qacEdelta, and blaCMY-4 in Vibrio cholerae isolates from Africa. Fluoroquinolone resistance mutations (gyrA_S83I and parC_S85L) and nitrofuran resistance mutations (nfsA_R169C and nfsB_Q5*) were also prevalent.
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