Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
tetracycline-resistant ribosomal protection protein
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| tet(T) | Card DatabaseResFinder Database | 2 | MINOCYCLINE, TETRACYCLINE +1 | Streptococcus pyogenes +1 | - | 1997 | L42544.1 | AAF01499.1 |
| Tet(T) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 11 | tetracycline, MINOCYCLINE +4 | Streptococcus pyogenes +9 | North Carolina|Ohio, Europe, Poland, Russia | 1997, 2001, 2005, 2011, 2022 | M85225|X56353|X04388|X75073|U08812|U58986|L12241|L12242|M21136|X90939|L09756|X92946|Y07780|M20925|M18896|AJ222769|Z21523|U73497|L33696|Y08615|X58717|L42544|L20800|M74049|X53401 | AAV80410.1 |
| tetT | Reslit | 8 | tetracycline | Enterococcus hirae R17 +7 | China, Changsha, Bulgaria, China|Xinjiang | 2017, 2019, 2020, 2021, 2025 | CP015516|CP015517 | - |
| TETT | Reslit | 1 | tetracycline | Bacteroidetes +2 | Alberta, Canada | 2019 | - | - |
Molecular ecology of tetracycline resistance: development and validation of primers for detection of tetracycline resistance genes encoding ribosomal protection proteins.
The study identified and characterized multiple tetracycline resistance genes encoding ribosomal protection proteins (RPPs) including tet(M), tet(O), tet(W), tet(Q), tet(S), tet(T), tetB(P), and otrA. These genes were detected in various bacterial species and environments, highlighting their prevalence and potential for horizontal gene transfer.
Analysis of the prevalence of tetracycline resistance genes in clinical isolates of Enterococcus faecalis and Enterococcus faecium in a Japanese hospital.
Analysis of the prevalence of tetracycline resistance genes in clinical isolates of Enterococcus faecalis and Enterococcus faecium in a Japanese hospital.
Development and Application of Real-Time PCR Assays for Quantification of Genes Encoding Tetracycline Resistance
The study developed and validated real-time PCR assays to quantify ten major classes of tetracycline resistance genes (tet) in microbiome samples, revealing significant differences in tet gene abundance between bovine and swine manures, with swine manures showing higher levels. Composting significantly reduced tet gene abundance.
Environmental macrolide-lincosamide-streptogramin and tetracycline resistant bacteria.
The paper discusses the characterization of environmental macrolide-lincosamide-streptogramin (MLS) and tetracycline resistance genes, highlighting the diversity and distribution of these genes in environmental bacteria. It identifies several MLS resistance genes such as erm(H), erm(I), erm(N), and others, as well as tetracycline resistance genes like tetA(P), tet(V), and tet(X).
Genomic insights into the pathogenicity and environmental adaptability of Enterococcus hirae R17 isolated from pork offered for retail sale.
The study identified multiple antimicrobial resistance genes in Enterococcus hirae R17, including genes conferring resistance to beta-lactam antibiotics, lincosamides, streptogramins, pleuromutilins, polymyxins, tetracyclines, and others. Notably, the strain exhibited resistance to bacitracin, ciprofloxacin, daptomycin, erythromycin, and tetracycline.
Whole Genome Sequencing and Comparative Genomics Analyses of Pandoraea sp. XY-2, a New Species Capable of Biodegrade Tetracycline.
The study identifies two tetracycline resistance genes, tetR and tetG, in Pandoraea sp. XY-2, suggesting its capability to biodegrade tetracycline.
Independent Microevolution Mediated by Mobile Genetic Elements of Individual Clostridium difficile Isolates from Clade 4 Revealed by Whole-Genome Sequencing.
The study identified multiple antimicrobial resistance genes, including aac(6')-Ib, ermB, tetM, and catD, in Clostridium difficile isolates from clade 4, highlighting the role of mobile genetic elements in the evolution of multidrug resistance.
Comparative diversity of microbiomes and Resistomes in beef feedlots, downstream environments and urban sewage influent.
The study identified several tetracycline, macrolide, aminoglycoside, beta-lactam, sulfonamide, mercury, and biocide resistance genes in beef feedlots, catch basin water, soil, and urban sewage influent. Tetracycline resistance was predominant in beef production systems, while urban sewage influent showed a diverse resistome with resistance to multiple antimicrobial classes.
Antibiotic Resistance Patterns of Pseudomonas spp. Isolated From Raw Milk Revealed by Whole Genome Sequencing.
The study identified various AMR genes and mutations in Pseudomonas spp. isolated from raw milk, highlighting the prevalence of multidrug-resistant strains and the presence of resistance determinants such as beta-lactamases, aminoglycoside-modifying enzymes, and efflux pumps.
Complete genome analysis of a virulent Vibrio scophthalmi strain VSc190401 isolated from diseased marine fish half-smooth tongue sole, Cynoglossus semilaevis.
The study identified several AMR genes in Vibrio scophthalmi strain VSc190401, including those conferring resistance to aminoglycosides, fluoroquinolones, tetracyclines, and polymyxins. Some of these genes were validated experimentally.
Chicken Manure and Mushroom Residues Affect Soil Bacterial Community Structure but Not the Bacterial Resistome When Applied at the Same Rate of Nitrogen for 3 Years.
The study identified several antibiotic resistance genes (ARGs) in chicken manure, mushroom residues, and heat-treated chicken manure, highlighting the impact of different organic manures on the soil resistome. Key findings include the enrichment of specific ARGs such as aadE, aadD, qacE1, qacH, lnuA, vatE, and tetL in soils treated with various manures, indicating the potential for ARG transfer through manure application.
Tetracycline, Macrolide and Lincosamide Resistance in Streptococcus canis Strains from Companion Animals and Its Genetic Determinants.
The study identified tetracycline resistance genes tet(O), tet(M), and tet(T), and MLS resistance genes erm(B) and erm(TR) in Streptococcus canis strains from companion animals.
Distribution Patterns of Antibiotic Resistance Genes and Their Bacterial Hosts in a Manure Lagoon of a Large-Scale Swine Finishing Facility.
The study identified multiple antibiotic resistance genes (ARGs) in manure samples from a swine finishing facility, highlighting the prevalence of resistance to tetracyclines, macrolides, aminoglycosides, and other antibiotics. Key genes included tet(M), lnuA, erm(35), aadS, mphB, dfrG, vga-type ABC-F, lsa-type ABC-F, msr-type ABC-F, optrA, and others, primarily found in Firmicutes, Proteobacteria, and Bacteroidota. These genes were associated with resistance mechanisms such as target alteration, antibiotic inactivation, and efflux pumps.
Relationship Between CRISPR-Cas Systems and Acquisition of Tetracycline Resistance in Non-Clinical Enterococcus Populations in Bulgaria.
The study identified tetM, tetS, tetO, and tetT genes as the primary tetracycline resistance genes in non-clinical Enterococcus populations in Bulgaria. These genes were found in various Enterococcus species, with tetM being the most prevalent. The presence of these genes was associated with the Tn916 transposon, indicating horizontal gene transfer mechanisms.
Virulence and resistance gene analysis of Rothia nasimurium by whole gene sequencing.
The study identified multiple AMR genes in Rothia nasimurium Y1, including vanA, vanC, vanB, vanE, vanD, vanG, vanF, vanM, vanL, vanO, vanN, mtrA, vanRA, arlR, vanRI, vanRB, vanRC, vanRD, vanRF, vanRG, CpxR, kdpE, vanRM, vanRN, baeR, adeR, vanRL, smeR, gyrA, gyrB, parC, Mfd, mfd, PBP2, PBP2x, EF-Tu, dfrE, pncA, tetB(P), tetQ, tet44, tetT, tetW, tetS, tetM, tetO, otr(A), tet36, tet32, clbC, clbB, clbA, cipA, cfrA, cfrC, sul3, ParY, murA, cls, and ileS, which confer resistance to various antibiotics such as glycopeptides, beta-lactams, fluoroquinolones, tetracyclines, sulfonamides, aminoglycosides, lincosamides, phenicols, macrolides, and others.
New tetracycline resistance determinants coding for ribosomal protection in streptococci and nucleotide sequence of tet(T) isolated from Streptococcus pyogenes A498.
The study identified a new tetracycline resistance determinant, tet(T), in Streptococcus pyogenes A498, which confers resistance through ribosomal protection.
New tetracycline resistance determinants coding for ribosomal protection in streptococci and nucleotide sequence of tet(T) isolated from Streptococcus pyogenes A498.
New tetracycline resistance determinants coding for ribosomal protection in streptococci and nucleotide sequence of tet(T) isolated from Streptococcus pyogenes A498.
New tetracycline resistance determinants coding for ribosomal protection in streptococci and nucleotide sequence of tet(T) isolated from Streptococcus pyogenes A498.
New tetracycline resistance determinants coding for ribosomal protection in streptococci and nucleotide sequence of tet(T) isolated from Streptococcus pyogenes A498., Analysis of the prevalence of tetracycline resistance genes in clinical isolates of Enterococcus faecalis and Enterococcus faecium in a Japanese hospital.
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