Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
tetracycline efflux MFS transporter Tet(Z)
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Tet(Z) | Reference Gene Catalog | 1 | TETRACYCLINE | Corynebacterium glutamicum | - | - | AF121000.1 | - |
| tet(Z) | Card DatabaseResFinder DatabaseReslit | 9 | TETRACYCLINE, DOXYCYCLINE +2 | Corynebacterium glutamicum +6 | United States, Europe, St. Kitts, Germany, North America, China|North America|Asia|Europe|Africa|Other | 2000, 2002, 2007, 2011, 2021, 2022, 2025 | AF121000.1 | AAD25063.1 |
| tet Z | Reslit | 1 | tetracycline | Bacillus cereus +2 | Yangzhou City | 2018 | KX981212|KX981438|KY048431|KY048441 | - |
| TETZ | Reslit | 1 | tetracycline | Bacteroidetes +2 | Alberta, Canada | 2019 | - | - |
| tetZ | Reslit | 1 | tetracycline | Mycobacterium abscessus +2 | - | 2022 | - | - |
| TetZ | Reslit | 1 | tetracycline | Trueperella pyogenes | India|Iran|UK|China|Brazil|US|Australia | 2022 | PESV00000000 | - |
TetZ, a new tetracycline resistance determinant discovered in gram-positive bacteria, shows high homology to gram-negative regulated efflux systems.
Development, validation, and application of PCR primers for detection of tetracycline efflux genes of gram-negative bacteria.
The study developed and validated PCR primers for detecting tetracycline efflux genes in gram-negative bacteria, identifying multiple tet genes in swine feed, feces, and groundwater, highlighting the spread of tetracycline resistance in agricultural environments.
Monitoring and Source Tracking of Tetracycline Resistance Genes in Lagoons and Groundwater Adjacent to Swine Production Facilities over a 3-Year Period
The study identified and characterized seven tetracycline resistance genes (tet(M), tet(O), tet(Q), tet(W), tet(C), tet(H), and tet(Z)) in lagoons and groundwater near swine production facilities over a 3-year period. These genes were consistently detected in groundwater and lagoon samples, with varying frequencies and concentrations depending on the location and sampling time.
Environmental macrolide-lincosamide-streptogramin and tetracycline resistant bacteria.
The paper discusses the characterization of environmental macrolide-lincosamide-streptogramin (MLS) and tetracycline resistance genes, highlighting the diversity and distribution of these genes in environmental bacteria. It identifies several MLS resistance genes such as erm(H), erm(I), erm(N), and others, as well as tetracycline resistance genes like tetA(P), tet(V), and tet(X).
High diversity and abundance of cultivable tetracycline-resistant bacteria in soil following pig manure application.
The study identifies several tetracycline resistance genes (tet B, tet L, tet Z, tet M, tet O, and tet X) in cultivable tetracycline-resistant bacteria from pig manure and soil, highlighting the diversity and abundance of these genes following pig manure application.
Comparative diversity of microbiomes and Resistomes in beef feedlots, downstream environments and urban sewage influent.
The study identified several tetracycline, macrolide, aminoglycoside, beta-lactam, sulfonamide, mercury, and biocide resistance genes in beef feedlots, catch basin water, soil, and urban sewage influent. Tetracycline resistance was predominant in beef production systems, while urban sewage influent showed a diverse resistome with resistance to multiple antimicrobial classes.
Comprehensive Molecular Dissection of Dermatophilus congolensis Genome and First Observation of tet(Z) Tetracycline Resistance.
The study reports the first observation of the tet(Z) gene, which confers tetracycline resistance, in Dermatophilus congolensis. The gene was detected in 12 isolates and is likely located on a plasmid.
The resistomes of Mycobacteroides abscessus complex and their possible acquisition from horizontal gene transfer.
The study identifies numerous AMR genes in Mycobacteroides abscessus complex, highlighting the widespread presence of resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, glycopeptides, and others. Key findings include the detection of beta-lactamases like blaLAP-1 and blaTLA-2, 23S rRNA methyltransferases such as erm(33), erm(43), and erm(44), and various aminoglycoside modifying enzymes. Additionally, vancomycin resistance genes like vanA, vanB, and vanC were identified, along with efflux pump genes contributing to multidrug resistance.
Comparative Genome Analysis of 19 Trueperella pyogenes Strains Originating from Different Animal Species Reveal a Genetically Diverse Open Pan-Genome.
The study identified 40 antibiotic resistance genes (ARGs) in 19 Trueperella pyogenes strains, including genes conferring resistance to aminoglycosides, tetracyclines, phenicols, sulfonamides, and macrolides.
Farming Practice Influences Antimicrobial Resistance Burden of Non-Aureus Staphylococci in Pig Husbandries.
The study found that organic and alternative pig farming practices are associated with reduced antimicrobial resistance (AMR) in non-aureus staphylococci (NAS) compared to conventional farming. Specific AMR genes such as mecA, blaZ, blaPC1, and others were more prevalent in conventional farms, while organic farms showed lower levels of AMR genes for aminoglycosides, phenicols, and tetracyclines.
Impact of doxycycline post-exposure prophylaxis for sexually transmitted infections on the gut microbiome and antimicrobial resistome.
The study found that doxy-PEP use over 6 months significantly increased the proportion and expression of tetracycline resistance genes in the gut microbiome, with no significant changes in other antibiotic resistance gene classes.
Global phylogeography and genomic characterization of bla(NDM-1)-positive clinical Proteus mirabilis isolates from China.
The study identifies blaNDM-1 as a key determinant of carbapenem resistance in Proteus mirabilis isolates from China, along with other resistance genes such as blaCTX-M-14, blaCTX-M-65, and blaTEM-1. It also characterizes the genomic context of blaNDM-1, including its integration into SGI1 and plasmid-borne elements.
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