tet(x5.3)

View on PubMed

flavin-dependent monooxygenase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to tet(x5.3)

AMR Rules

Browse AMR rules for tet(x5.3)

Validation StatusCandidate

Overview

Validation Method: cloning in E.coli + susceptibility testing
Drug Classes: tigecycline, tetracycline
Organisms: Acinetobacter spp.
Geographic Location: China
Papers: 1
Databases: Reslit

Papers1

Genetic diversity and characteristics of high-level tigecycline resistance Tet(X) in Acinetobacter species.

PMID 33287863 · 2020

Four tet(X) variants (tet(X3), tet(X4), tet(X5.2), and tet(X5.3)) were identified in Acinetobacter species, showing high-level resistance to tigecycline, tetracycline, eravacycline, and omadacycline. These genes were found in multiple Acinetobacter species and were associated with IS CR2 elements, facilitating their spread.

Gene Information

Gene Name: tet(x5.3)
Allele: tet(X5.3)
Encodes: flavin-dependent monooxygenase
Source Database: Reslit
Confers Resistance To: tigecyclinetetracycline
Organisms Tested In: • Acinetobacter spp.
Geographic Location: China
Validation Method: cloning in E.coli + susceptibility testing
Sequence Accession: CP040912|CP014021

Comments (0)

No comments yet. Be the first to comment!

tet(x5.3)

Gene Information

Browse AMR Genes

tet(x5.3)

Gene Information