tet(x7.2)

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tetracycline destructase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to tet(x7.2)

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Validation StatusCandidate

Overview

Validation Method: expression in E. coli and antibiotic susceptibility testing
Drug Classes: tetracycline, doxycycline, tigecycline
Organisms: Escherichia coli
Papers: 1
Databases: Reslit

Papers1

Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes.

PMID 38493211 · 2024

The study identified 14 new tetracycline destructases (TDases) through HMM screening and functional validation, expanding the diversity of TDase sequences and providing insights into their sequence-structure-function relationships.

Gene Information

Gene Name: tet(x7.2)
Allele: Tet(X7.2)
Encodes: tetracycline destructase
Source Database: Reslit
Confers Resistance To: tetracyclinedoxycyclinetigecycline
Organisms Tested In: • Escherichia coli
Validation Method: expression in E. coli and antibiotic susceptibility testing
Sequence Accession: 8TWG|8TWF

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tet(x7.2)

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tet(x7.2)

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