Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
major facilitator superfamily (MFS) antibiotic efflux pump
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| H121R | - | - | Shigella spp., E. coli, Salmonella spp. | tetracycline | Reslit | Candidate |
| S251A | - | - | Klebsiella pneumoniae, Escherichia coli | tigecyclinetigecycline|tetracycline|minocycline | Reslit | Candidate |
| I235V | - | - | Escherichia coli | tigecycline | Reslit | Candidate |
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Cstr_tetA | Card Database | 1 | - | Corynebacterium striatum | - | - | NC_004939.1 | NP_862226.1 |
| tetA | Card DatabaseReference Gene CatalogReslit | 570 | TETRACYCLINE, tetracycline +5 | Corynebacterium striatum +244 | England|Norway|Germany, Italy, Laos, Toronto, Canada|Vancouver, Canada|India, India|Mexico|Egypt|Morocco|Peru|Kenya|Senegal|Mali|South Africa|Vietnam|Nepal|Indonesia|Bolivia|Equatorial Guinea|Uganda|Cameroon|Guatemala|Philippines|Burkina-Faso, France, Canada, Madrid, Spain, United States, Brazil, Atlantic Canada, China, South Africa, Korea, Europe|United States|Australia, Asia|Africa|Europe|South America|Global, Europe, US, Germany, Thailand, Australia, Iran, Madagascar, Taiwan|India|Morocco|Hong Kong, Denmark, USA|Brazil|United States, Eastern China, India, Spain, Poland, Nepal, Tunisia, Japan|Thailand|Canada|France|Spain|South Korea|United Kingdom|Croatia|Vietnam|global, Ho Chi Minh City, Vietnam, Ecuador, poultry, Eastern Cape Province, South Africa, Israel, Eastern Cape, South Africa, Malaysia, Greece, Europe|Portugal, Egypt, United Kingdom|Ireland, Saudi Arabia, San Francisco|Seattle|Minnesota|Minneapolis|Sacramento|Dallas|Jackson, Delhi, India, West Bengal, Europe|Italy, pig|duck, England, USA|Australia|Canada|Japan|France|Madagascar|China|Thailand|Germany, Global, Uganda, Rio de Janeiro, Brazil, Maryland|District of Columbia, Chile, La Paz, Bolivia|La Paz River basin, Senegal, China|Brazil|United Kingdom|Denmark, developing countries, shellfish, Delta State, Nigeria, Tanzania|Thailand|human|swine, Egypt|Africa|Europe|Asia|Middle East|Indonesia|India|USA, Jordan, UK, Southeastern Brazil, Utah, Northern Thailand, Alberta, Canada, Chattogram, Bangladesh, swine, Denmark|Japan, Maputo, Mozambique, Nigeria, Netherlands, Tai'an, China, Japan, Europe|Southern and Western Ireland, Bangladesh, Brazil|Santa Catarina|Minas Gerais|Paraná|São Paulo|Rio de Janeiro|Rio Grande do Sul, Spain|porcine, northern Xinjiang, China|China, Madagascar|Cambodia|Senegal, Turkey, Indonesia, Switzerland|chicken, Abbottabad|Pakistan, South Africa|various water sources, West Cameroon, Embu Town|Kangaru Market, Europe|Czech Republic|Slovak Republic, North America|turtle, Eastern Cape Province, Republic of South Africa|South Africa, Serbia, Sweden, Sicily|Southern Italy, Vietnam, France|The Netherlands, Northwestern Sicily, Italy|Europe, North America|Asia|Europe|Australia|South America, Chitwan, Nepal, South Korea, Europe|United States, Portugal|Porto, North Upper Egypt|Egypt, Slovakia, India|Malaysia|South China, Portugal, Brasília, Brazil, Europe|China|Egypt|Vietnam|Colombia, Europe|Poland, Kelantan|Terengganu, New York State, Quebec|Ontario|France|Switzerland, Norway, Northeastern Ohio, the United States|Northeastern Ohio, Northeast Tunisia, Hong Kong, Mecklenburg-Western Pomerania, Milwaukee, Wisconsin, USA|USA, Tanzania, Romania|France, Europe|North America|Netherlands|Denmark|Pennsylvania|United States|France, Kuwait, United Kingdom, Mexico, Kenya, Guangxi Province, Georgia, USA|Georgia, Singapore, Pakistan, North America|Asia|Europe|Middle East|Africa, Shandong Province|China, South America, Europe|USA|Portugal|Germany|Australia|China|India|Pakistan|Sweden|Colorado, UK|France, Nepal|Kathmandu, Nepal, South Africa|Europe, Abuja, Nigeria, Democratic Republic of Congo|Democratic Republic of the Congo, Peru, Anhui Province, Quetta Balochistan, South America|Australia|France|Vietnam|China, Switzerland, Southwest Nigeria, Zhejiang, China|China, Iraq, Algeria, Shijiazhuang, Hebei Province, Ghana, Uruguay, Anhui, China, Shaanxi Province, Northern Kazakhstan, Portugal|Denmark|Saudi Arabia|China|Australia|United Arab Emirates|Turkey|Sweden|Norway|Germany|Egypt|Belgium|Netherlands|Canada|USA|Europe|global, Nghe An province, Vietnam, Western Africa|Mali, Taiyuan City, Shanxi Province, China, Wenzhou, China, Sicily, Pakistan|Karachi, Pakistan, Sichuan|Heilongjiang|Anhui|MY|LA|DQ, Northern Italy, Brazil|Belgium, Oman, Colombia, USA, North Carolina, Southeast Brazil, Peruvian Amazon, Quebec, Canada, USA|China|India|Thailand|Brazil|Hungary|South Africa|Egypt|Tunisia|Europe|Asia, South-Eastern Bangladesh|Bangladesh, Brazil|Europe|United Kingdom|United States, Bangladesh|India|China|France|Brazil, Bangkok, Thailand, Hebei Province|China|Hebei Province, China, China|India|Portugal|Iraq|Nigeria|Brazil|Tunisia, Punjab, Pakistan, Jos, Nigeria, Anhui province, China, Switzerland|Europe, Indonesia|Australia, Europe|Russia, Portugal|various regions, Fujian Province, Southeast China|China, France|Germany|Netherlands|Norway|Spain|United Kingdom|Europe, Europe|South America|Asia|North Africa, Somali region, Ethiopia|Somali Region, Ethiopia, Europe|Africa|North America|South America|Asia|Oceania, Zimbabwe, Romania, Northwestern Transylvania, Romania, Middle Upper Egypt, Calabria|Italy, Abakaliki, Nigeria, Qatar, China|Anhui|Hainan|Sichuan, Indonesia|USA|China|Europe|Finland, Guizhou province, China|Guizhou, China, Jiangxi province, China|Jiangxi Province, Central Zone of Mexico|Mexico, Ibadan, Nigeria, Greater Accra Region, Ghana|Ghana, United Arab Emirates, Mansoura, Egypt, Europe|Turkey, China|Europe|Americas|Asia|North Africa|Middle East, Shandong Province, Northern Nigeria|Nigeria, USA|China|Spain|Australia|Japan|Switzerland|Netherlands|Brazil|Taiwan|New Hampshire, USA|global, Southern Benin|Benin, Mekong Delta, Vietnam, Harare, Zimbabwe, Upper Egypt|Egypt, Central Adriatic Sea, Southeastern Nigeria|Nigeria, Krasnodar Krai, Russia|Russia | 1999, 2000, 2002, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025, 2026 | U21300.1 | AAC95479.1 |
| tet A | Reslit | 38 | tetracycline, doxycycline +1 | Salmonella enterica +22 | South Africa|Brazil, India, northern Xinjiang, China|China, Italy, Bangladesh, South Africa, Western Cape, South Africa, Guangdong Province, Europe, Bangkok, Thailand, Egypt, Eastern Cape province, South Africa|South Africa, West Bengal, India, Edo State, Nigeria, north-central Nigeria, United States, China, Oregon, USA|Oregon, Portugal|various regions, Portugal, Iran, Shandong, China, Algeria, India|Delhi NCR | 2016, 2018, 2020, 2021, 2022, 2023, 2024, 2025 | KX300038–KX300086|KY432753|KU573047–KU573052|KY924468–KY924470 | - |
| tetA/R | Reslit | 1 | tetracycline | Escherichia coli +1 | United States|coastal wetlands | 2017 | KX863568|KX863570|KX863569|KX863571|KF245926.1|KY018700 | - |
| Tet A | Reslit | 1 | tetracycline | broiler chicken +2 | United States | 2021 | - | - |
| tetA/B | Reslit | 2 | tetracycline | Escherichia coli +1 | Poland, China | 2024, 2025 | PRJEB23993 | - |
The 51,409-bp R-plasmid pTP10 from the multiresistant clinical isolate Corynebacterium striatum M82B is composed of DNA segments initially identified in soil bacteria and in plant, animal, and human pathogens.
The 51,409-bp R-plasmid pTP10 from the multiresistant clinical isolate Corynebacterium striatum M82B is composed of DNA segments initially identified in soil bacteria and in plant, animal, and human pathogens.
Distribution of Oxytetracycline Resistance Plasmids between Aeromonads in Hospital and Aquaculture Environments: Implication of Tn1721 in Dissemination of the Tetracycline Resistance Determinant Tet A
The study identifies the tetracycline resistance determinant tetA as a key gene in the dissemination of oxytetracycline resistance among Aeromonas species in both hospital and aquaculture environments, highlighting the role of Tn1721 in this process.
Genetic determinants of tetracycline resistance in Vibrio harveyi.
Two tetracycline resistance determinants, tetA and tet35, were identified in Vibrio harveyi M3.4L. Both genes conferred resistance to tetracycline, oxytetracycline, and minocycline when cloned in E. coli.
Antibiotic Resistance Genes and Salmonella Genomic Island 1 in Salmonella enterica Serovar Typhimurium Isolated in Italy.
The study identifies antibiotic resistance genes and the presence of Salmonella Genomic Island 1 (SGI1) in multidrug-resistant Salmonella enterica serovar Typhimurium isolates from Italy. Key resistance genes include aadA2, pse-1, floR, tetA, and tetR, which contribute to resistance against various antibiotics.
Antibiotic Resistance Conferred by a Class I Integron and SXT Constin in Vibrio cholerae O1 Strains Isolated in Laos.
The study identifies the presence of a class I integron with the aadA1 gene cassette and an SXT constin in Vibrio cholerae O1 strains from Laos, which confer resistance to multiple antibiotics including streptomycin, chloramphenicol, tetracycline, and sulfamethoxazole.
Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extended-spectrum beta-lactamase involved in an outbreak in long-term-care facilities in Toronto, Canada.
The study reports the complete nucleotide sequence of a 92-kilobase plasmid, pC15-1a, which harbors the CTX-M-15 extended-spectrum beta-lactamase, along with other resistance genes such as blaOXA-1, blaTEM-1, aac(6')-Ib, aac(3)-II, and tetA. These genes contribute to multidrug resistance in Escherichia coli strains associated with an outbreak in long-term-care facilities in Toronto, Canada.
Mechanism of resistance to several antimicrobial agents in Salmonella Clinical isolates causing traveler's diarrhea.
The study identified several AMR genes and mutations in Salmonella isolates causing traveler's diarrhea, including blaTEM, blaOXA-1, tetA, tetB, tetG, dfrA1, dfrA12, dfrA14, dfrA17, floR, cmlA, and a mutation in the gyrA gene. These genes and mutations contribute to resistance against ampicillin, tetracycline, trimethoprim, chloramphenicol, and quinolones.
Mechanisms of resistance in multiple-antibiotic-resistant Escherichia coli strains of human, animal, and food origins.
Combining mathematical models and statistical methods to understand and predict the dynamics of antibiotic-sensitive mutants in a population of resistant bacteria during experimental evolution.
The study identified the deletion of the tetracycline-resistance operon (tetA and tetR) in E. coli K12(pB10) as the cause of tetracycline sensitivity, demonstrating that this deletion occurred through recombination between direct repeats on the plasmid.
Tetracycline-inducible gene regulation in mycobacteria.
The study describes a tetracycline-inducible gene regulation system in mycobacteria using the tetRO region from Corynebacterium glutamicum's TetZ determinant. This system allows for controlled gene expression in both fast-growing and slow-growing mycobacteria, including M. smegmatis, M. bovis BCG, and M. tuberculosis.
Comparative genomics of multidrug resistance in Acinetobacter baumannii.
The study identifies numerous resistance genes in the multidrug-resistant Acinetobacter baumannii strain AYE, including beta-lactamases, aminoglycoside-modifying enzymes, tetracycline resistance genes, and others, highlighting the complexity of its resistance mechanisms.
Characterization of antimicrobial resistance of Salmonella Newport isolated from animals, the environment, and animal food products in Canada.
The study identified several AMR genes in Salmonella Newport isolates, including bla CMY-2, flo st, strA, strB, sulII, tetA, and aphA-1, which confer resistance to various antibiotics such as extended-spectrum cephalosporins, chloramphenicol, streptomycin, sulfonamides, tetracycline, kanamycin, and neomycin.
Spread of Escherichia coli Strains with High-Level Cefotaxime and Ceftazidime Resistance between the Community, Long-Term Care Facilities, and Hospital Institutions.
The study identifies the spread of Escherichia coli strains with high-level resistance to cefotaxime and ceftazidime, primarily due to the presence of extended-spectrum beta-lactamases (ESBLs) such as CTX-M-15, CTX-M-14, and CTX-M-32. Additionally, other resistance genes like tetA, dfrA14, dfrA17, sul1, sul2, aac(6')Ib, and aac(3)IIb were found to contribute to multidrug resistance.
Biochemical and molecular characterization of tetracycline-resistant Aeromonas veronii isolates from catfish.
The study identified tetE as the predominant tetracycline resistance gene in Aeromonas veronii isolates from catfish, followed by tetB, tetA, tetC, and tetD.
The involvement of tetA and tetE tetracycline resistance genes in plasmid and chromosomal resistance of Aeromonas in Brazilian strains.
The study identified tetA and tetE tetracycline resistance genes in Aeromonas strains from Brazil, demonstrating their role in plasmid and chromosomal resistance. The plasmid pSS2 was shown to carry the tetA gene and contribute to tetracycline resistance.
Transferable, multiple antibiotic and mercury resistance in Atlantic Canadian isolates of Aeromonas salmonicida subsp. salmonicida is associated with carriage of an IncA/C plasmid similar to the Salmonella enterica plasmid pSN254.
The study identifies multiple antibiotic and mercury resistance genes carried by an IncA/C plasmid in Atlantic Canadian isolates of Aeromonas salmonicida subsp. salmonicida, including aadA7, floR, tetA, sulII, strA, strB, blaCMY-2, and a mercury resistance operon.
Genetic characterization of clinical and agri-food isolates of multi drug resistant Salmonella enterica serovar Heidelberg from Canada.
The study identified the bla_cmy-2 gene as a major contributor to extended-spectrum cephalosporin resistance in Salmonella enterica serovar Heidelberg isolates, with the gene also found in E. coli isolates. The gene was located on high-molecular-weight plasmids and contributed to multidrug resistance.
Antimicrobial resistance genes in Escherichia coli isolates recovered from a commercial beef processing plant
The study identified various antimicrobial resistance genes in E. coli isolates from a commercial beef processing plant, including beta-lactamase genes (blaCMY, blaSHV, blaTEM), tetracycline resistance genes (tetA, tetB, tetC), sulfonamide resistance genes (sul1, sul2), and aminoglycoside resistance genes (strA, strB).
Longitudinal characterization of resistant Escherichia coli in fecal deposits from cattle fed subtherapeutic levels of antimicrobials.
The study identified several AMR genes, including blaTEM1, tetA, tetB, tetC, sul1, and sul2, in Escherichia coli from cattle fecal deposits. These genes conferred resistance to ampicillin, tetracycline, and sulfonamides.
Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches.
The study identifies multiple AMR genes in Edwardsiella tarda EIB202, including tetA, tetR, strA, strB, sulII, and catA3, which confer resistance to tetracycline, streptomycin, sulfonamide, and chloramphenicol.
Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042.
The study identifies several antibiotic resistance genes in the enteroaggregative E. coli strain 042, including cat, tetA, aadA1, suI, and emrE, which contribute to resistance against chloramphenicol, tetracycline, streptomycin, spectinomycin, sulfonamide, and ethidium bromide.
Antibiotic susceptibility profiles of some Vibrio strains isolated from wastewater final effluents in a rural community of the Eastern Cape Province of South Africa.
The study identified several antibiotic resistance genes in Vibrio strains isolated from wastewater effluents, including dfrA1, dfr18, floR, sul2, strB, and tetA, which confer resistance to trimethoprim, chloramphenicol, sulfamethoxazole, streptomycin, and tetracycline.
Multidrug-resistant Salmonella enterica serovar Infantis, Israel.
Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes.
The study identifies several antimicrobial resistance genes in the plasmid of the adherent-invasive E. coli strain NRG857c, including blaTEM, tetC, tetA, catI, dhfrI, sulII, and sulI, which confer resistance to ampicillin, tetracycline, chloramphenicol, and sulfonamides.
Efflux-mediated antibiotic resistance in Acinetobacter spp.
The study characterizes several efflux pumps in Acinetobacter spp., including AdeABC, AdeIJK, AdeFGH, CraA, AmvA, AbeM, AbeS, AdeXYZ, AdeDE, TetA, TetB, CmlA, FloR, and QacE, which contribute to multidrug resistance by expelling antibiotics and other compounds.
Stochastic simulations of the tetracycline operon.
The study investigates the dynamics of the tetracycline operon, focusing on the genes tetR and tetA, which encode the repressor protein TetR and the transport protein TetA, respectively. These genes are crucial for tetracycline resistance in bacteria.
Molecular characterization of tetracycline- and quinolone-resistant Aeromonas salmonicida isolated in Korea.
The study identified tetA and tetE genes as the primary determinants of tetracycline resistance in Korean Aeromonas salmonicida isolates, along with point mutations in gyrA and parC contributing to quinolone resistance.
Antimicrobial resistance, virulence-associated genes, and pulsed-field gel electrophoresis profiles of Salmonella enterica subsp. enterica serovar Typhimurium isolated from piglets with diarrhea in Korea.
The study identified multiple antimicrobial resistance genes in Salmonella enterica subsp. enterica serovar Typhimurium isolates from piglets with diarrhea in Korea, including bla PSE, bla TEM, cat1, cat2, floR, strA, strB, aadA, sulI, sulII, tetA, tetC, and tetG.
Diversity and evolution of AbaR genomic resistance islands in Acinetobacter baumannii strains of European clone I.
The study characterizes various AbaR genomic resistance islands in Acinetobacter baumannii strains of European clone I, identifying multiple AMR genes such as blaTEM-1, aacC1, aadA1, aacA4, dfrA1, catA1, sul1, and tetA, which confer resistance to beta-lactams, aminoglycosides, chloramphenicol, sulfonamides, and tetracyclines.
Genomic analysis of the multidrug-resistant Acinetobacter baumannii strain MDR-ZJ06 widely spread in China.
The study identifies several AMR genes and mutations in the multidrug-resistant Acinetobacter baumannii strain MDR-ZJ06, including bla oxa-23, armA, and various efflux pumps, contributing to resistance against multiple antibiotics.
Emergence of a globally dominant IncHI1 plasmid type associated with multiple drug resistant typhoid.
The study identifies the emergence of a globally dominant IncHI1 plasmid type (PST6) associated with multiple drug-resistant typhoid. Key resistance genes include blaTEM-1, cat, dfrA7, sul1, sul2, strAB, tetA, tetD, and betU, which contribute to resistance against ampicillin, chloramphenicol, trimethoprim, sulfamethoxazole, streptomycin, tetracycline, and high salt environments.
Plasmidic qnrA3 enhances Escherichia coli fitness in absence of antibiotic exposure.
The study shows that the plasmidic qnrA3 gene enhances the fitness of Escherichia coli in the absence of antibiotic exposure, indicating a potential regulatory role of qnr genes beyond direct antibiotic resistance.
Mainstreams of horizontal gene exchange in enterobacteria: consideration of the outbreak of enterohemorrhagic E. coli O104:H4 in Germany in 2011.
The study identified various genomic islands (GIs) in enterobacteria, including those carrying antibiotic resistance genes such as beta-lactamase (bla), tetracycline efflux protein (tet), and mercury resistance operon (mer). These GIs were found to be horizontally transferred and contributed to the virulence and resistance profiles of the strains analyzed.
Impact of antibiotic treatments on the expression of the R plasmid tra genes and on the host innate immune activity during pRAS1 bearing Aeromonas hydrophila infection in zebrafish (Danio rerio).
The study characterizes the resistance genes dfr16, sul1, and tetA in the pRAS1 plasmid of Aeromonas hydrophila, showing their role in resistance to trimethoprim, sulfonamide, and tetracycline, respectively.
Dynamics of transcription driven by the tetA promoter, one event at a time, in live Escherichia coli cells.
The study characterizes the tetA gene, which encodes a membrane-targeted antiporter protein responsible for tetracycline efflux in Escherichia coli, demonstrating its role in tetracycline resistance through experimental validation.
Detection and sequencing of plasmid encoded tetracycline resistance determinants (tetA and tetB) from food-borne Bacillus cereus isolates.
The study identified the presence of tetA and tetB genes in food-borne Bacillus cereus isolates, indicating plasmid-mediated tetracycline resistance and potential horizontal gene transfer.
Identification of novel genomic islands and transposons encoding genes that may contribute to host specificity and Salmonella transmission
The study identified various antibiotic resistance genes in Salmonella plasmids, including beta-lactamases (bla CTX, bla CMY, bla TEM), aminoglycoside resistance genes (aadA1, aadA2, strA, strB), tetracycline resistance gene (tetA), chloramphenicol resistance gene (cmlA), sulfonamide resistance gene (sul2), and genes conferring resistance to heavy metals and disinfectants (sugE, arsR, cusR, silE, qacH).
The shared antibiotic resistome of soil bacteria and human pathogens.
The study identifies multiple antibiotic resistance genes in soil bacteria that are identical to those found in human pathogens, highlighting the exchange of resistance genes between environmental and clinical microbes.
Development and Evaluation of a Microarray-Based Serogenotyping Assay for Salmonella
The study presents a microarray-based serogenotyping assay for Salmonella, demonstrating high correlation between genotypic and phenotypic characteristics. Several AMR genes were identified and validated, showing strong association with AMR phenotypes.
Comparative sequence analysis of a multidrug-resistant plasmid from Aeromonas hydrophila.
The study identifies multiple AMR genes in the multidrug-resistant plasmid pR148 from Aeromonas hydrophila, including blaOXA-10, aadA1, sul1, catA2, and tetA, which confer resistance to beta-lactams, aminoglycosides, sulfonamides, chloramphenicol, and tetracyclines, respectively.
DNA sequence analysis of plasmids from multidrug resistant Salmonella enterica serotype Heidelberg isolates.
The study identified multiple antimicrobial resistance genes in plasmids from multidrug-resistant Salmonella enterica serotype Heidelberg isolates, including bla CMY, aadA, aadB, aphA, strA, strB, sul1, sul2, tetA, floR, cmlA, dfrA1, dfrA12, and aacC.
Outbreak investigation using high-throughput genome sequencing within a diagnostic microbiology laboratory.
The study identified the blaCTX-M-15 gene, aadA1, tetA, and dfrA1 as resistance determinants in multidrug-resistant Escherichia coli strains during an outbreak. Additionally, quinolone resistance mutations in gyrA (S83L, D87N) and parC (S80I, E84V) were detected.
Altering the selection capabilities of common cloning vectors via restriction enzyme mediated gene disruption.
The study describes a method to alter the selectable marker of cloning vectors by inserting different resistance genes, allowing the replacement of ampicillin resistance with tetracycline or kanamycin resistance.
Molecular clonality and antimicrobial resistance in Salmonella enterica serovars Enteritidis and Infantis from broilers in three Northern regions of Iran.
The study identified multiple antimicrobial resistance genes, including aadA1, floR, dfrA14, sulI, and tetA, in Salmonella enterica serovars Enteritidis and Infantis from broilers in Iran. These genes were associated with resistance to streptomycin, florfenicol, trimethoprim, sulfamethoxazole, and tetracycline, respectively. Additionally, a single mutation in the gyrA gene was found to confer resistance to nalidixic acid and ciprofloxacin.
Molecular characterization of multidrug-resistant extended-spectrum β-lactamase-producing Enterobacteriaceae isolated in Antananarivo, Madagascar.
The study identified bla CTX-M-15 and bla SHV-12 as the predominant ESBL genes in multidrug-resistant Enterobacteriaceae isolates in Antananarivo, along with other resistance genes such as aac(6')-Ib, tetA, sul1, sul2, qnrA, qnrB, and catB-3.
Copy Number Change of the NDM-1 sequence in a multidrug-resistant Klebsiella pneumoniae clinical isolate.
The study identifies the blaNDM-1 gene on plasmid pKPX-1 as a key factor in carbapenem resistance in a multidrug-resistant Klebsiella pneumoniae isolate. It also characterizes additional resistance genes such as aac(6')-Ib, aac(6')-Ib-cr, aph(3')-I, strB, qnrB, tetA, catA1, and catB4, which contribute to resistance against aminoglycosides, fluoroquinolones, tetracycline, and chloramphenicol.
DNA microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii clinical isolates.
The study developed a DNA microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii clinical isolates, identifying numerous resistance genes and mutations associated with carbapenem, aminoglycoside, fluoroquinolone, and other antibiotic resistances.
Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes.
The study identified several antibiotic resistance genes in Achromobacter xylosoxidans NH44784-1996, including beta-lactamases, tetracycline efflux proteins, and macrolide resistance genes, indicating its resistance to various antibiotics.
Characterization of class 1 integrons and antibiotic resistance genes in multidrug-resistant Salmonella enterica isolates from foodstuff and related sources.
The study identified several AMR genes, including aadA, sul1, sul2, tetA, blaTEM-1, and qacEAI, associated with resistance to streptomycin, sulfamethoxazole-trimethoprim, tetracycline, ampicillin, and quaternary ammonium compounds, respectively. A mutation in the gyrA gene (Ser83Phe) was linked to resistance to nalidixic acid and enrofloxacin.
Aquatic environments polluted with antibiotics and heavy metals: a human health hazard.
The study identified the tetracycline resistance gene tetA in two Pseudomonas aeruginosa isolates, EW32 and EW33, which exhibited resistance to tetracycline. The gene was found on conjugative plasmids, highlighting the role of plasmids in the spread of antibiotic resistance.
Comparative genomic analysis and virulence differences in closely related salmonella enterica serotype heidelberg isolates from humans, retail meats, and animals.
The study identified several AMR genes and mutations in Salmonella enterica serotype Heidelberg isolates, including bla, aac(6')-Ib, tet(M), qnrS1, and erm(B). Mutations in genes such as SEEHRA37_03221, SEEHRA37_24108, and others were associated with resistance traits.
Characterization of multidrug-resistant Salmonella enterica serovars Indiana and Enteritidis from chickens in Eastern China.
The study identified multiple AMR genes including blaTEM, floR, tetA, strA, and aac(6')-Ib-cr in multidrug-resistant Salmonella enterica serovars Indiana and Enteritidis from chickens in Eastern China.
A comprehensive insight into tetracycline resistant bacteria and antibiotic resistance genes in activated sludge using next-generation sequencing.
The study identifies several tetracycline resistance genes (tetA, tetC, and tetG) in activated sludge exposed to tetracycline, highlighting their increased abundance and diversity under tetracycline stress. It also reveals the presence of novel tetracycline-resistant bacteria genera.
Characterization of Escherichia coli virulence genes, pathotypes and antibiotic resistance properties in diarrheic calves in Iran.
The study identified several antibiotic resistance genes in E. coli isolates from diarrheic calves in Iran, including aadA1, sul1, aac[3]-IV, dfrA1, tetA, and tetB, which confer resistance to streptomycin, sulfonamide, gentamicin, trimethoprim, and tetracycline.
Antimicrobial resistance, virulence profiles and molecular subtypes of Salmonella enterica serovars Typhi and Paratyphi A blood isolates from Kolkata, India during 2009-2013.
The study identified several AMR genes in Salmonella enterica serovars Typhi and Paratyphi A, including blaTEM-1, catA, sul1, sul2, dfrA15, aadA1, strA, strB, and intI1, which contribute to resistance against various antibiotics such as ampicillin, chloramphenicol, co-trimoxazole, streptomycin, and others.
Prevalence and antibiogram profiling of Escherichia coli pathotypes isolated from the Kat River and the Fort Beaufort abstraction water.
The study identified the presence of antibiotic resistance genes aadA, tetA, and bla in E. coli isolates from the Kat River and Fort Beaufort abstraction water, indicating resistance to streptomycin, tetracycline, and beta-lactam antibiotics.
Phylogenetic distribution and prevalence of genes encoding class I Integrons and CTX-M-15 extended-spectrum β-lactamases in Escherichia coli isolates from healthy humans in Chandigarh, India.
The study identifies the presence of class 1 integrons and bla CTX-M-15 genes in commensal E. coli isolates from healthy individuals in Chandigarh, India. It also detects several gene cassettes conferring resistance to trimethoprim, streptomycin, spectinomycin, streptothricin, chloramphenicol, tetracycline, and sulfonamides.
Diversity, distribution and quantification of antibiotic resistance genes in goat and lamb slaughterhouse surfaces and meat products.
The study identified various tetracycline, sulfonamide, and beta-lactam resistance genes in goat and lamb slaughterhouse surfaces and meat products, highlighting the prevalence of tet genes and their potential role in the spread of antibiotic resistance.
Prevalence of virulence determinants and antimicrobial resistance among commensal Escherichia coli derived from dairy and beef cattle.
The study identified several antimicrobial resistance genes in commensal E. coli from dairy and beef cattle, including blaTEM, blaSHV, aadA1, tetA, tetB, and tetC. These genes conferred resistance to ampicillin, streptomycin, and tetracycline. Dairy cattle isolates showed higher resistance rates compared to beef cattle.
Draft Genome Sequence of a New Delhi Metallo-β-Lactamase-5 (NDM-5)-Producing Multidrug-Resistant Escherichia coli Isolate.
The study reports the identification of blaNDM-5 along with multiple other antibiotic resistance genes in a multidrug-resistant E. coli isolate, highlighting the complex resistance profile of the strain.
Clinical epidemiology and molecular analysis of extended-spectrum-β-lactamase-producing Escherichia coli in Nepal: characteristics of sequence types 131 and 648.
The study identified bla CTX-M-15, aac (3)-IIa, aadA1, aadA2, aadA5, qnrB4, qnrS1, aac (6')-Ib-cr, bla OXA-1, bla TEM-1B, bla SHV-12, bla CMY-42, bla DHA-1, mphA, ermB, catA1, catB3, sul1, sul2, dfrA12, dfrA17, dfrA1, dfrA5, tetA, tetB, and tetD as key AMR genes in ESBL-producing E. coli isolates in Nepal, highlighting the prevalence of multidrug resistance.
Occurrence of bla CTX-M-1, qnrB1 and virulence genes in avian ESBL-producing Escherichia coli isolates from Tunisia.
The study identified blaCTX-M-1, qnrB1, tetA, tetB, sul1, sul2, and sul3 genes in avian ESBL-producing E. coli isolates from Tunisia, highlighting their role in resistance to beta-lactams, quinolones, and sulfonamides.
Complete Genome Sequence of ER2796, a DNA Methyltransferase-Deficient Strain of Escherichia coli K-12.
The study reports the complete genome sequence of ER2796, a DNA methyltransferase-deficient strain of Escherichia coli K-12. The strain lacks native DNA methylation due to the inactivation of three endogenous methyltransferases (dam, dcm, and hsdM). Additionally, the yhdJ gene was permanently inactivated in the derivative strain ER3413.
Insight into the mobilome of Aeromonas strains.
The study characterizes various antibiotic resistance genes (ARG) in Aeromonas strains, highlighting the presence of beta-lactamases, aminoglycoside-modifying enzymes, tetracycline resistance genes, and others. These genes are often located on plasmids and contribute to multidrug resistance.
Genetic characterization of three qnrS1-harbouring multidrug-resistance plasmids and qnrS1-containing transposons circulating in Ho Chi Minh City, Vietnam.
The study characterizes three qnrS1-harbouring multidrug-resistance plasmids and identifies qnrS1-containing transposons circulating in Ho Chi Minh City, Vietnam. It reveals that qnrS1 is part of a transposon structure that includes additional resistance genes such as blaLAP-2, aacC3, sulII, tetR, tetA, and blaCTX-M-14.
Effects of selection pressure and genetic association on the relationship between antibiotic resistance and virulence in Escherichia coli.
The study identifies tetA, tetB, intl1, and qnrB as genes associated with antibiotic resistance in Escherichia coli, highlighting their roles in tetracycline, sulfamethoxazole-trimethoprim, and quinolone resistance.
Draft Genome Sequence of a Pathogenic O86:H25 Sequence Type 57 Escherichia coli Strain Isolated from Poultry and Carrying 12 Acquired Antibiotic Resistance Genes.
The study reports the draft genome sequence of an E. coli strain carrying 12 acquired antibiotic resistance genes, including beta-lactamases, aminoglycoside modifying enzymes, sulfonamide resistance, trimethoprim resistance, tetracycline resistance, and streptothricin resistance.
Multiple antibiotic resistances among Shiga toxin producing Escherichia coli O157 in feces of dairy cattle farms in Eastern Cape of South Africa.
The study identified multiple antibiotic resistance genes in Shiga toxin-producing Escherichia coli O157 isolates from dairy cattle farms in South Africa, including blaampC, blacmy, blactxm, blatem, tetA, and strA.
Genomic and Functional Characterization of qnr-Encoding Plasmids from Municipal Wastewater Biosolid Klebsiella pneumoniae Isolates.
The study identified two types of plasmids harboring qnr genes in Klebsiella pneumoniae isolates from municipal wastewater biosolids. One plasmid, pKPSH-11XL, was a large multidrug-resistant IncF plasmid containing qnrB, beta-lactamase genes, tetracycline resistance genes, aminoglycoside resistance genes, and chloramphenicol resistance genes. Another group of smaller plasmids contained qnrS and other resistance genes.
Identification and antimicrobial resistance prevalence of pathogenic Escherichia coli strains from treated wastewater effluents in Eastern Cape, South Africa.
The study identified several AMR genes in E. coli isolates from wastewater effluents, including strA, aadA, catI, cmlA1, blaTEM, and various tetracycline resistance genes (tetA, tetB, tetC, tetD, tetK, tetM). These genes conferred resistance to multiple antibiotics such as streptomycin, gentamicin, chloramphenicol, ampicillin, and tetracycline.
Comparative Genomics of Two ST 195 Carbapenem-Resistant Acinetobacter baumannii with Different Susceptibility to Polymyxin Revealed Underlying Resistance Mechanism.
The study identified blaOXA-23 and blaAmpC genes contributing to carbapenem and extended-spectrum cephalosporin resistance, and mutations in pmrA, pmrB, lpxD, lpxC, and lpsB genes linked to polymyxin resistance in A. baumannii AC30.
Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments.
The study shows that sub-inhibitory levels of tetracyclines can potentiate selection for or against tetracycline resistance in the presence of various stresses. It highlights the role of the TetA efflux pump in mediating tetracycline resistance and how environmental factors influence the selective pressure on antibiotic resistance.
Relation between tetR and tetA expression in tetracycline resistant Escherichia coli.
The study characterizes the tetracycline resistance genes tetA and tetR in Escherichia coli, demonstrating their expression is regulated by tetracycline concentration and growth phase.
Multidrug Efflux Systems in Microaerobic and Anaerobic Bacteria.
The paper discusses the role of multidrug efflux pumps in microaerobic and anaerobic bacteria, highlighting their importance in antibiotic resistance. Several efflux systems were identified and characterized, including CmeABC, CmeDEF, CmeG, NhaA1/NhaA2, HefABC, HefDEF, HefGHI, NorB, BmeABC1-16, BexA, MdtEF, CusCBA, AcrAB, TolC, TetA, XepCAB, and bcRABD, each contributing to resistance against various antibiotics.
Complex Interplay of Physiology and Selection in the Emergence of Antibiotic Resistance.
The study characterizes the tetracycline resistance gene tetA, which is stochastically expressed in E. coli populations, leading to resistance emergence under fluctuating antibiotic stress.
Prevalence of virulence and antimicrobial resistance genes in Salmonella spp. isolated from commercial chickens and human clinical isolates from South Africa and Brazil.
The study identified the presence of virulence and antimicrobial resistance genes in Salmonella isolates from commercial chickens and human clinical samples in South Africa and Brazil. Key resistance genes included pse-1 (ampicillin), ant (3")-la (gentamicin), tet A and tet B (tetracycline), and sul 1 and sul 2 (sulfamethoxazole).
Whole-Genome Sequencing for Detecting Antimicrobial Resistance in Nontyphoidal Salmonella.
The study identified 65 unique resistance genes in nontyphoidal Salmonella, including bla CTX-M1 and bla SHV2a, which were first reported in retail meat isolates in the United States. The research highlights the effectiveness of whole-genome sequencing in detecting antimicrobial resistance genes and correlating them with phenotypic resistance.
Streaming algorithms for identification of pathogens and antibiotic resistance potential from real-time MinION(TM) sequencing.
The study presents a real-time analysis framework for MinION sequencing data, demonstrating the ability to identify pathogens and antibiotic resistance genes within a few hours of sequencing. Key resistance genes identified include blaSHV, mphA, strA, strB, blaTEM, sul2, blaOXA, aac3, aac6, blaCMY, blaCFE, blaLAT, blaBIL, QnrB, aadA, oqxA, tetA, oqxB, rmtC, sul1, sul3, fosA, blaNDM, oqxA, blaSHV, oqxB, aadB, sul1, sul3, blaOXA, blaOKP, fosA, blaSHV, blaOKP, blaLEN, oqxA, and oqxB.
Corrected Genome Annotations Reveal Gene Loss and Antibiotic Resistance as Drivers in the Fitness Evolution of Salmonella enterica Serovar Typhimurium.
The study identifies antibiotic resistance genes and genomic islands in Salmonella enterica serovar Typhimurium, highlighting the role of horizontal gene transfer in the acquisition of multidrug resistance and fitness-related genes.
Architecture of Class 1, 2, and 3 Integrons from Gram Negative Bacteria Recovered among Fruits and Vegetables.
The study identified several AMR genes in Gram-negative bacteria from fresh produce, including mcr-1, qnrA1, blaGES-11, mphA, and oqxAB, highlighting the presence of mobile genetic elements and clinically relevant resistance genes.
Effects of Menthol Supplementation in Feedlot Cattle Diets on the Fecal Prevalence of Antimicrobial-Resistant Escherichia coli.
The study found that menthol supplementation in feedlot cattle diets increased the prevalence of tetracycline-resistant E. coli isolates. Specifically, 56.9% of isolates from the menthol group were resistant to tetracycline compared to 32.7% in the control group. The study also identified the presence of tetA and tetB genes in the resistant isolates.
Determination of antibiotic resistance genes in relation to phylogenetic background in Escherichia coli isolates from fecal samples of healthy pet cats in Kerman city.
The study identified several antibiotic resistance genes in E. coli isolates from healthy pet cats, including tetB, tetA, aadA, sulI, qnrS, and dhfrV, with varying prevalence rates. These genes were associated with resistance to tetracycline, aminoglycosides, sulfonamides, fluoroquinolones, and trimethoprim.
Epidemiological, molecular characterization and antibiotic resistance of Salmonella enterica serovars isolated from chicken farms in Egypt.
The study identified various AMR genes in Salmonella enterica serovars isolated from chicken farms in Egypt, including blaTEM, aadA2, floR, cat1, sul1, sul3, tetC, tetA, and intI, which confer resistance to ampicillin, streptomycin, chloramphenicol, sulfamethoxazole, tetracycline, and multiple antibiotics.
Outer Membrane Proteins form Specific Patterns in Antibiotic-Resistant Edwardsiella tarda.
The study identifies specific outer membrane protein patterns associated with antibiotic resistance in Edwardsiella tarda, highlighting the role of plasmid-encoded genes such as tetA, tetR, and catA in mediating resistance to tetracycline and chloramphenicol.
Evolution and Epidemiology of Multidrug-Resistant Klebsiella pneumoniae in the United Kingdom and Ireland.
The study identifies several AMR genes and mutations associated with multidrug-resistant Klebsiella pneumoniae in the UK and Ireland, including beta-lactamases, aminoglycoside-modifying enzymes, tetracycline efflux pumps, and mutations in gyrB contributing to fluoroquinolone resistance.
Prevalence, serotyping and antimicrobials resistance mechanism of Salmonella enterica isolated from clinical and environmental samples in Saudi Arabia.
The study identified several AMR genes and mutations in Salmonella enterica isolates from Saudi Arabia, including carb-like, dfrA1, floR, tetA, and mutations in gyrA and parC genes associated with resistance to beta-lactams, trimethoprim-sulfamethoxazole, chloramphenicol, tetracycline, and fluoroquinolones.
Subcellular Chemical Imaging of Antibiotics in Single Bacteria Using C(60)-Secondary Ion Mass Spectrometry.
The study demonstrates the use of C(60)-ToF-SIMS for visualizing the subcellular localization of antibiotics in single E. coli cells, showing that tetracycline (TET) and ampicillin (AMP) accumulate within the cells. The presence of the tetracycline resistance gene tetA was shown to significantly reduce TET accumulation in E. coli.
Genomic Analysis of Factors Associated with Low Prevalence of Antibiotic Resistance in Extraintestinal Pathogenic Escherichia coli Sequence Type 95 Strains.
The study identifies several AMR genes in ST95 E. coli strains, including blaTEM-1, blaCTX-M14, aadA1, aadA2, aadA5, aac3, strA, strB, tetA, tetB, tetD, sul1, sul2, dfrA5, dfrA12, dfrA17, mphA, and catA1, which confer resistance to various antibiotics such as ampicillin, cephalothin, streptomycin, tetracycline, sulfamethoxazole, trimethoprim, azithromycin, and chloramphenicol.
Distribution of Integrons and Phylogenetic Groups among Enteropathogenic Escherichia coli Isolates from Children <5 Years of Age in Delhi, India.
The study identified various AMR genes including dfrA1, dfrA7, dfrA12, aadA1, aadA2, sul1, tetA, aacC1, TEM, SHV, CTX-M, OXA, NDM-1, IMP, VIM, ACT, DHA, and CMY in E. coli isolates from children in Delhi, India. These genes were associated with resistance to multiple antibiotics such as trimethoprim, streptomycin, sulfonamides, tetracycline, gentamicin, and various beta-lactams.
Detection of emerging antibiotic resistance in bacteria isolated from subclinical mastitis in cattle in West Bengal.
The study identified blaCTX-M, blaTEM, tetA, and tetB genes in Gram-negative bacteria isolated from subclinical mastitis in cattle in West Bengal, indicating the presence of antibiotic resistance mechanisms.
Viromes As Genetic Reservoir for the Microbial Communities in Aquatic Environments: A Focus on Antimicrobial-Resistance Genes.
The study identified tetracycline resistance genes (tetA-C, tetE, tetG, and tetH) in viromes and microbiomes of the Lambro River, demonstrating their mobilization in response to tetracycline exposure.
Characterization of the emerging zoonotic pathogen Arcobacter thereius by whole genome sequencing and comparative genomics.
The study characterizes the genome of Arcobacter thereius, identifying metabolic pathways and potential antibiotic resistance mechanisms. No specific AMR genes were experimentally validated in this study.
Characterization of the emerging zoonotic pathogen Arcobacter thereius by whole genome sequencing and comparative genomics.
The study characterizes the genome of Arcobacter thereius, identifying metabolic pathways and potential antibiotic resistance mechanisms. No specific AMR genes were experimentally validated in this study.
Characterization of a Large Antibiotic Resistance Plasmid Found in Enteropathogenic Escherichia coli Strain B171 and Its Relatedness to Plasmids of Diverse E. coli and Shigella Strains.
The study characterized a large antibiotic resistance plasmid, pB171_90, from EPEC strain B171, identifying several AMR genes including aadA1, sul1, tetA, tetR, qacE Δ 1, csi, hha, and traI.
Insight into synergetic mechanisms of tetracycline and the selective serotonin reuptake inhibitor, sertraline, in a tetracycline-resistant strain of Escherichia coli.
The study identifies the tetracycline resistance gene tetA in E. coli APEC_O2 and demonstrates that sertraline enhances the efficacy of tetracycline by reducing its MIC, suggesting a synergistic effect independent of AcrAB-TolC efflux pump inhibition.
Systematic longitudinal survey of invasive Escherichia coli in England demonstrates a stable population structure only transiently disturbed by the emergence of ST131.
The study identified various antibiotic resistance genes, including bla CTX-M-15, aac(6')-Ib, bla OXA-1, bla TEM-1, dfrA, mphA, sul1, and tetA, in E. coli isolates, highlighting the multidrug-resistant nature of ST131 and the presence of distinct plasmid profiles contributing to resistance.
Comparative Sequence Analysis of Multidrug-Resistant IncA/C Plasmids from Salmonella enterica.
The study identified multiple antimicrobial resistance genes on IncA/C plasmids from various Salmonella serovars, including bla_cmy-2, bla_tem-1, strA, strB, aadB, aph(3')-Ia, tetA, floR, cmlA, sul1, sul2, dfra12, quacE, sugE, merA, merB, merC, merD, and merE, which contribute to multidrug resistance.
Molecular characterization of antimicrobial multi-drug resistance in non-typhoidal Salmonellae from chicken and clam in Mangalore, India.
Characterization of Four Multidrug Resistance Plasmids Captured from the Sediments of an Urban Coastal Wetland.
Four multidrug resistance plasmids were captured from the sediments of an urban coastal wetland. These plasmids carried various resistance genes, including beta-lactamases, tetracycline resistance genes, sulfonamide resistance genes, and others, conferring resistance to multiple antibiotics.
ARIBA: Rapid identification of antimicrobial resistance genes and variants from whole-genome sequencing data
The paper presents ARIBA, a tool for identifying antimicrobial resistance genes and mutations from sequencing data. It evaluates the performance of ARIBA on three datasets, demonstrating its accuracy and efficiency in detecting resistance genes and mutations in Enterococcus faecium, Shigella sonnei, and Neisseria gonorrhoeae.
Characterization of multiple antibiotic resistance of culturable microorganisms and metagenomic analysis of total microbial diversity of marine fish sold in retail shops in Mumbai, India.
The study identified multiple antibiotic resistance genes in marine fish isolates, including blaTEM, Class I integron, tetA, aph(3')-IIIa, ermB, aadA, and sul1, indicating a potential risk of antibiotic resistance transmission to humans through the food chain.
Porcine commensal Escherichia coli: a reservoir for class 1 integrons associated with IS26.
The study identified 17 antimicrobial resistance genes (ARGs) in 103 class 1 integron-positive Escherichia coli strains from porcine feces, highlighting the prevalence of multidrug-resistant commensal E. coli in pigs and their potential role in the dissemination of resistance genes.
The Role for the Small Cryptic Plasmids As Moldable Vectors for Genetic Innovation in Aeromonas salmonicida subsp. salmonicida.
The study identifies three new plasmids, pAsa10, pAsaXI, and pAsaXII, in Aeromonas salmonicida subsp. salmonicida. pAsa10 carries the tetracycline resistance gene tetA, pAsaXI contains a transposon with a potential virulence factor, and pAsaXII includes a formaldehyde detoxification system. These plasmids demonstrate the role of cryptic plasmids in genetic innovation and resistance mechanisms.
Diversity and Antimicrobial Resistance Genotypes in Non-Typhoidal Salmonella Isolates from Poultry Farms in Uganda.
The study identified several antimicrobial resistance genes in non-typhoidal Salmonella isolates from Ugandan poultry farms, including blaTEM-1, cmlA, qnrS, tetA, sul1, dhfrI, and dhfrVII, which confer resistance to various antibiotics such as ampicillin, chloramphenicol, ciprofloxacin, tetracycline, sulfonamide, and trimethoprim.
pSTM6-275, a Conjugative IncHI2 Plasmid of Salmonella enterica That Confers Antibiotic and Heavy-Metal Resistance under Changing Physiological Conditions.
The IncHI2 plasmid pSTM6-275 from Salmonella enterica carries multiple antibiotic and heavy-metal resistance genes, including blaTEM, strA, strB, sul3, aadA1, aadA2, cmlA, aphA2, tetA, mejB, silESRCFBAGP, and pcoGE1ABCDRSE2, which confer resistance to various antibiotics and metals. The plasmid exhibits temperature-dependent resistance to silver and copper, highlighting its adaptability under changing physiological conditions.
Detection of CTX-M-15 harboring Escherichia coli isolated from wild birds in Tunisia.
The study identifies CTX-M-15-harboring Escherichia coli in wild birds in Tunisia, highlighting the presence of multidrug resistance genes such as bla CTX-M-15, bla TEM-1b, tetA, qnrA1, qnrB1, aac(6')-Ib-cr, aac(3)-II, and sul3.
The Rapid Emergence of Tigecycline Resistance in bla(KPC-2) Harboring Klebsiella pneumoniae, as Mediated in Vivo by Mutation in tetA During Tigecycline Treatment.
The study identifies a mutation in the tetA gene (S251A) as the mechanism of tigecycline resistance in bla(KPC-2) harboring Klebsiella pneumoniae, demonstrating that this mutation leads to high-level tigecycline resistance and can be transferred via a plasmid.
Investigation of Efflux-Mediated Tetracycline Resistance in Shigella Isolates Using the Inhibitor and Real Time Polymerase Chain Reaction Method.
The study identified tetA and tetB genes as contributors to tetracycline resistance in Shigella isolates, with tetA being prevalent in S. sonnei and tetB in S. flexneri. Efflux pump inhibitors like CCCP reduced MIC values, indicating the involvement of efflux mechanisms in resistance.
Polyphyletic Nature of Salmonella enterica Serotype Derby and Lineage-Specific Host-Association Revealed by Genome-Wide Analysis.
The study identified AMR genes aadA2, sul1, and tetA in Salmonella enterica serovar Derby strains, with a multidrug-resistant profile STR-SSS-TET in certain lineages.
High genomic diversity of multi-drug resistant wastewater Escherichia coli.
The study identifies several known and novel resistance genes in wastewater-derived E. coli, highlighting the high genomic diversity and the presence of genes associated with resistance to various antibiotics.
A pan-genome-based machine learning approach for predicting antimicrobial resistance activities of the Escherichia coli strains.
The study identifies and characterizes several AMR genes in E. coli, including beta-lactamases (blaTEM-1, blaOXA-1, blaCMY-2, ampC), aminoglycoside modifying enzymes (aac(3')-Ia, aac(3')-VI), dihydrofolate reductases (dfrA1, dfrA5, dfrA12, dfrA15), quinolone resistance proteins (qnrB2, qnrB6, qnrS2), and others. These genes were validated through computational and wet lab methods, showing their roles in conferring resistance to various antibiotics.
Genome sequence of a multidrug-resistant Corynebacterium striatum isolated from bloodstream infection from a nosocomial outbreak in Rio de Janeiro, Brazil.
The study reports the draft genome of a multidrug-resistant Corynebacterium striatum isolate, identifying several resistance genes including tetA, tetB, vanW, ermX, aph(3')-Ia, strA-strB, bla, and cmx, along with a mutation in the gyrA gene contributing to quinolone resistance.
Antibiotic resistance gene dynamics in the gut microbiota following amoxicillin-clavulanic acid treatment
The study identified several AMR genes, including aminoglycoside resistance genes (ksgA, strA, strB), beta-lactam resistance genes (blaCARB-4, blaCMY-1, blaCMY-2, blaCTX-M-1, blaCTX-M-12, blaDHA-1, blaOXA-1, blaSHV-1, blaSHV-37, blaSHV-3, blaTEM-1A, blaTEM-1B), and tetracycline resistance genes (tetA, tetB, tetC, tetK, tetL), that were enriched in the gut microbiota of healthy adults following amoxicillin-clavulanic acid treatment.
Alterations of Salmonella enterica Serovar Typhimurium Antibiotic Resistance under Environmental Pressure.
The study identifies tetracycline resistance gene tetA and sulfonamide resistance gene sul2 in Salmonella enterica serovar Typhimurium, demonstrating their role in antibiotic resistance under environmental pressure.
Extended antibiotic treatment in salmon farms select multiresistant gut bacteria with a high prevalence of antibiotic resistance genes.
The study identifies several AMR genes, including floR, fexA, and various tetracycline resistance genes (tetA, tetB, tetE, tetH, tetL, tetM, tet34, tet35), associated with resistance to florfenicol and oxytetracycline in gut bacteria from salmon farms. These genes were found in multiple bacterial species, highlighting the widespread nature of AMR in aquatic environments.
A Fatal Bacteremia Caused by Hypermucousviscous KPC-2 Producing Extensively Drug-Resistant K64-ST11 Klebsiella pneumoniae in Brazil.
The study reports a fatal case of bacteremia caused by a hypermucoviscous KPC-2 producing extensively drug-resistant K64-ST11 Klebsiella pneumoniae. The isolate harbored multiple AMR genes including blaKPC-2, blaSHV-11, qnrS1, oqxA, oqxB, sul1, sul2, dfrA1, tetA, tetD, and fosA, contributing to its extensive drug resistance.
Using Machine Learning To Predict Antimicrobial MICs and Associated Genomic Features for Nontyphoidal Salmonella.
The study presents a machine learning model capable of predicting antimicrobial MICs for nontyphoidal Salmonella using whole-genome sequence data, identifying key genomic features associated with resistance.
Draft genome sequence data of a tigecycline-resistant Enterobacter cloacae ST93 clinical strain isolated from bloodstream infection.
The study reports the draft genome sequence of a tigecycline-resistant Enterobacter cloacae ST93 clinical isolate, TREC1, which harbors multiple antimicrobial resistance genes, including those encoding resistance to beta-lactams, aminoglycosides, fluoroquinolones, fosfomycin, macrolides, lincosamides, streptogramin B, phenicols, sulfonamides, trimethoprim, and tetracyclines. The isolate is resistant to all antibiotics tested except colistin.
Emerging Multidrug-Resistant Hybrid Pathotype Shiga Toxin-Producing Escherichia coli O80 and Related Strains of Clonal Complex 165, Europe.
The study identifies multidrug-resistant hybrid pathotype Shiga toxin-producing E. coli O80 strains belonging to clonal complex 165, which harbor a mosaic plasmid with genes conferring resistance to multiple antibiotics, including beta-lactams, tetracyclines, sulfonamides, trimethoprim, kanamycin, streptomycin, and colistin.
Diarrheal bacterial pathogens and multi-resistant enterobacteria in the Choqueyapu River in La Paz, Bolivia.
The study identified multidrug-resistant Enterobacteriaceae in the Choqueyapu River, including E. coli and Enterobacter cloacae carrying bla CTX-M, bla KPC, bla NDM, bla VIM, and bla OXA-48 genes, highlighting the environmental spread of antibiotic resistance.
Prevalence of antimicrobial resistance and potential pathogenicity, and possible spread of third generation cephalosporin resistance, in Escherichia coli isolated from healthy chicken farms in the region of Dakar, Senegal.
The study identified various AMR genes and mutations in E. coli isolates from healthy chicken farms in Senegal, including bla CTX-M, bla CMY-2, tetA, dfrA1, dfrA7, aadA1, qnrB, and bla TEM, as well as mutations in gyrA and parC genes contributing to ciprofloxacin resistance.
Draft Genome Sequence of an Enterococcus faecalis Strain (24FS) That Was Isolated from Healthy Infant Feces and Exhibits High Antibacterial Activity, Multiple-Antibiotic Resistance, and Multiple Virulence Factors.
The study reports the draft genome sequence of Enterococcus faecalis 24FS, highlighting its multiple-antibiotic resistance traits, including resistance to chloramphenicol, tetracycline, erythromycin, aminoglycosides, fluoroquinolones, trimethoprim, streptothricin, and streptomycin, along with potential virulence factors.
Loss and Gain in the Evolution of the Salmonella enterica Serovar Gallinarum Biovar Pullorum Genome.
The study identifies multiple multidrug resistance plasmids in Salmonella Pullorum, including pSPUR1, pSPUR2, pSPUR3, pSPUR4, and pSPUR5, which confer resistance to various antibiotics such as trimethoprim, streptomycin, sulfonamide, and tetracycline.
Diversity, Virulence, and Antimicrobial Resistance in Isolates From the Newly Emerging Klebsiella pneumoniae ST101 Lineage.
The study characterizes the antimicrobial resistance genes and mutations in the emerging Klebsiella pneumoniae ST101 lineage, highlighting the presence of multiple resistance mechanisms including carbapenemases, extended-spectrum beta-lactamases, and various other resistance genes.
Strain- and Species-Level Variation in the Microbiome of Diabetic Wounds Is Associated with Clinical Outcomes and Therapeutic Efficacy.
The study identifies specific AMR genes in Staphylococcus aureus strains associated with poor wound healing outcomes, including blaRIZ, ant1, tetA, and ermA, highlighting their role in antibiotic resistance and implications for therapeutic strategies.
Plasmids of Shigella flexneri serotype 1c strain Y394 provide advantages to bacteria in the host.
The study identifies the multidrug resistance plasmid pNV-Y394 in Shigella flexneri serotype 1c strain Y394, which carries the genes sul2, strA-strB, and tetA, conferring resistance to sulfonamide, streptomycin, and tetracycline, respectively.
Genomic Investigation of the Emergence of Invasive Multidrug-Resistant Salmonella enterica Serovar Dublin in Humans and Animals in Canada.
The study identifies multiple AMR genes and mutations in multidrug-resistant Salmonella enterica serovar Dublin isolates from Canada, highlighting the role of IS 26 in plasmid hybridization and the emergence of MDR strains.
Genomic Characterization of Arcobacter butzleri Isolated From Shellfish: Novel Insight Into Antibiotic Resistance and Virulence Determinants.
The study identified several antibiotic resistance genes in Arcobacter butzleri strains isolated from shellfish, including genes conferring resistance to beta-lactams, polymyxin, chloramphenicol, tetracycline, and macrolides.
Antimicrobial Resistance, Virulence Determinants, and Biofilm Formation of Enterococcus Species From Ready-to-Eat Seafood.
The study identified various antimicrobial resistance genes including ermA, ermB, ermC, mphC, vanA, vanB, tetA, and tetM in Enterococcus species isolated from ready-to-eat seafood, indicating the presence of multidrug-resistant strains.
Genotypic antimicrobial resistance assays for use on E. coli isolates and stool specimens.
The study developed and validated 85 PCR assays to detect 79 AMR genes and mutations associated with resistance across 10 antimicrobial classes, focusing on E. coli. The assays showed high concordance with sequencing and phenotypic susceptibility testing, demonstrating their potential for AMR surveillance in E. coli isolates and direct stool specimens.
Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198.
The study identifies multiple AMR genes and mutations in multidrug-resistant Salmonella enterica serotype Kentucky ST198, including genes such as blaTEM-1, aacA4, aadA1, sul1, tetA, catA1, mph(A), blaCTX-M-1, blaOXA-48, blaNDM-1, blaCMY-2, and dfrA12, along with mutations in gyrA and parC that confer resistance to various antibiotics.
Identification of Escherichia coli from broiler chickens in Jordan, their antimicrobial resistance, gene characterization and the associated risk factors.
The study identified several antimicrobial resistance genes in Escherichia coli isolates from broiler chickens in Jordan, including tetA, tetB, int1, sul1, sul2, blaTEM, and cat. These genes were associated with resistance to various antibiotics such as tetracycline, sulfonamides, beta-lactams, and chloramphenicol.
Diverse Commensal Escherichia coli Clones and Plasmids Disseminate Antimicrobial Resistance Genes in Domestic Animals and Children in a Semirural Community in Ecuador.
The study identified various antimicrobial resistance (AMR) genes in commensal Escherichia coli isolates from children and domestic animals in a semirural community in Ecuador. These genes included blaTEM-1B, dfrA8, qnrB19, strA, strB, tetA, tetB, sul1, sul2, and others, contributing to resistance against multiple antibiotics such as ampicillin, trimethoprim, tetracycline, and sulfamethoxazole. The research highlights the role of plasmids in disseminating these AMR genes and emphasizes the complexity of AMR transmission in such environments.
Edwardsiella piscicida: A versatile emerging pathogen of fish.
The study identifies multiple antibiotic resistance genes in Edwardsiella piscicida, including tetA, tetR, strA, strB, sulII, and catA3, which confer resistance to tetracycline, streptomycin, sulfonamides, and chloramphenicol.
Determining antimicrobial susceptibility in Salmonella enterica serovar Typhimurium through whole genome sequencing: a comparison against multiple phenotypic susceptibility testing methods.
The study identified various AMR genes and mutations in Salmonella enterica serovar Typhimurium, including aadA, strAB, blaTEM, blaCARB, floR, cmlA1, catA1, qnrB19, sul1, sul2, sul3, dfrA1, dfrA12, dfrA14, tetA, tetB, tetC, tetG, and mutations in gyrA. These genes and mutations were validated through whole genome sequencing and phenotypic ASTs.
Dissemination of Multidrug-Resistant Commensal Escherichia coli in Feedlot Lambs in Southeastern Brazil.
The study identified multiple multidrug-resistant commensal E. coli isolates in feedlot lambs in Brazil, carrying various AMR genes including bla CTX-M-2, bla CTX-M-8, bla CTX-M-14, bla CTX-M-15, bla CMY-2, aac(3)-IIa, ant(2")-Ia, qnrB, tetA, tetB, sul1, sul2, floR, and cmlA. These genes confer resistance to beta-lactams, aminoglycosides, quinolones, tetracyclines, sulfonamides, and phenicols.
Comparative Genomics and Phenotypic Investigations Into Antibiotic, Heavy Metal, and Disinfectant Susceptibilities of Salmonella enterica Strains Isolated in Australia.
The study identified several AMR genes and mutations in Salmonella enterica strains, including blaTEM-1, aph(3')-I, aph(6')-ld, dfrA5, tetA, and various arsenic resistance genes. A mutation in gyrA was also found to confer nalidixic acid resistance.
Molecular Epidemiology of Multidrug-Resistant Klebsiella pneumoniae Isolates in a Brazilian Tertiary Hospital.
The study identified various AMR genes and mutations in multidrug-resistant Klebsiella pneumoniae isolates, including bla KPC, bla CTX-M, bla TEM, and mutations in ompk35, ompk36, gyrA, and parC. These findings highlight the complex resistance mechanisms contributing to the persistence of MDR-Kp in the hospital setting.
Genomic Sequence Analysis of the Multidrug-Resistance Region of Avian Salmonella enterica serovar Indiana Strain MHYL.
The study identified several AMR genes, including blaTEM, strA, tetA, floR, and aac(6')-Ib-cr, in the multidrug-resistant Salmonella enterica serovar Indiana strain MHYL. These genes were localized in two distinct MDR regions, RR1 and RR2, and were associated with resistance to multiple antibiotics.
Population dynamics of an Escherichia coli ST131 lineage during recurrent urinary tract infection.
The study identified multiple AMR genes and mutations in E. coli ST131 isolates from a patient with recurrent UTIs, including plasmid-borne resistance genes and chromosomal mutations contributing to fluoroquinolone resistance.
Multilocus sequence typing and bla (ESBL) characterization of extended-spectrum beta-lactamase-producing Escherichia coli isolated from healthy humans and swine in Northern Thailand.
The study identified bla CTX-M, bla TEM, and bla SHV as the primary ESBL genes in ESBL-producing E. coli isolates from healthy humans and swine in Northern Thailand. Additionally, several other AMR genes such as sul1, sul2, sul3, aadA22, aph(3')-Ia, strA, strB, aadA2, aadA5, qnrS1, tetA, tetB, tetD, arr2, and mefB were characterized.
Characterization of Non-O157 Escherichia coli from Cattle Faecal Samples in the North-West Province of South Africa.
The study identified several antimicrobial resistance genes in non-O157 E. coli isolates from cattle fecal samples, including tetA, tetB, blaTEM-1, aadA1, and catA1, which were associated with resistance to tetracycline, ampicillin, streptomycin, and chloramphenicol.
Comparative diversity of microbiomes and Resistomes in beef feedlots, downstream environments and urban sewage influent.
The study identified several tetracycline, macrolide, aminoglycoside, beta-lactam, sulfonamide, mercury, and biocide resistance genes in beef feedlots, catch basin water, soil, and urban sewage influent. Tetracycline resistance was predominant in beef production systems, while urban sewage influent showed a diverse resistome with resistance to multiple antimicrobial classes.
Comparative Genomics of Antibiotic-Resistant Uropathogens Implicates Three Routes for Recurrence of Urinary Tract Infections.
The study identifies various beta-lactamase genes, including bla CTX-M-98, bla CTX-M-27, bla OXA-1, and bla TEM-1, which confer resistance to multiple antibiotics in uropathogens. These genes were functionally characterized through whole-genome sequencing and antibiotic susceptibility testing.
Phenotypic and genotypic characterization of antibiotic-resistant in Escherichia coli isolates from patients with diarrhea.
The study identified several antibiotic resistance genes in E. coli isolates from patients with diarrhea, including dfrA1, sul1, citm, tetA, and qnr, which contribute to resistance against trimethoprim, sulfamethoxazole, ampicillin, tetracycline, and ciprofloxacin, respectively.
Antibiotic resistance of Escherichia coli isolated from broilers sold at live bird markets in Chattogram, Bangladesh.
The study identified multidrug-resistant Escherichia coli isolates carrying blaTEM, tetA, and Sul2 genes, which confer resistance to ampicillin, tetracycline, and sulfomethoxazole-trimethoprim, respectively.
Genomic comparison of diverse Salmonella serovars isolated from swine.
The study identified various AMR genes in Salmonella serovars isolated from swine, including beta-lactamases (bla TEM-1, bla CMY-2, bla CARB-2), tetracycline resistance genes (tetA, tetB, tetC, tetG), aminoglycoside resistance genes (aadA2, strA, strB), sulfonamide resistance genes (sul1, sul2, sul3), florfenicol resistance gene (floR), and dihydrofolate reductase genes (dfrA1, dfrA7, dfrA12, dfrA16), as well as erythromycin esterase (ereA).
WGS based study of the population structure of Salmonella enterica serovar Infantis.
The study identified multiple resistance genes, including aadA1, sul1, tetA, and dfrA14, carried on a pESI-like plasmid in multidrug-resistant Salmonella enterica serovar Infantis strains.
Gut carriage of antimicrobial resistance genes among young children in urban Maputo, Mozambique: Associations with enteric pathogen carriage and environmental risk factors.
The study identified several antimicrobial resistance genes (ARGs) in the gut of young children in urban Maputo, Mozambique, including aadA1, SHV, ermA, ermB, mefA, tetA, tetB, and others, which confer resistance to various antibiotics such as aminoglycosides, beta-lactams, macrolides, tetracyclines, and fluoroquinolones.
Evolution of Antibiotic Resistance and the Relationship between the Antibiotic Resistance Genes and Microbial Compositions under Long-Term Exposure to Tetracycline and Sulfamethoxazole.
The study identified the expansion of tetracycline and sulfonamide resistance genes, particularly tetC and sul1, under long-term exposure to tetracycline and sulfamethoxazole in wastewater treatment systems.
Molecular Detection Of Multidrug-Resistant Salmonella Isolated From Livestock Production Systems In South Africa.
The study identified multiple multidrug-resistant Salmonella isolates from livestock in South Africa, highlighting the presence of resistance genes such as blaTEM-1, blaCMY-2, tetA, tetC, sul2, and dfrA7.
Characterization of a Novel Conjugative Plasmid in Edwardsiella piscicida Strain MS-18-199.
The study characterizes a novel conjugative plasmid, pEPMS-18199, in Edwardsiella piscicida strain MS-18-199, which carries multiple antimicrobial resistance (AMR) genes including floR, tetA, tetR, sul2, strA, strB, arsA, and arsD, conferring resistance to phenicol, tetracycline, sulfonamide, and aminoglycoside antibiotics, as well as arsenic.
Effects of a Four-Week High-Dosage Zinc Oxide Supplemented Diet on Commensal Escherichia coli of Weaned Pigs.
The study identifies several antibiotic resistance genes (ARGs) and zinc tolerance genes in commensal Escherichia coli from weaned pigs, highlighting the impact of high-dose zinc oxide diets on selecting for resistant strains.
A large self-transmissible resistance plasmid from Nigeria contains genes that ameliorate a carrying cost.
The study identifies a large self-transmissible plasmid pMB2 from Nigeria containing multiple resistance genes, including aac(6')-Ib-cr, blaCTX-M-15, tetA, and sitABCD, which contributes to antimicrobial resistance and provides a growth advantage under iron-limited conditions.
Impact of commonly used drugs on the composition and metabolic function of the gut microbiota.
The study identifies several AMR genes, including tetA, tetB, Mel, TolC, and mdtP, which are associated with resistance to tetracyclines and macrolides, and are influenced by drug use in the gut microbiota.
Molecular characterization of avian pathogenic Escherichia coli from broiler chickens with colibacillosis.
The study identified several AMR genes in APEC isolates, including beta-lactamases (bla TEM-1, bla CTX-M-1, bla CTX-M-15), aminoglycoside-modifying enzymes (aac(3)-II), plasmid-mediated quinolone resistance genes (qnrA, qnrS), tetracycline resistance genes (tetA), sulfonamide resistance genes (sul2), and chloramphenicol resistance genes (catA1, cmlA).
Prevalence and characteristics of multidrug-resistant mcr-1-positive Escherichia coli isolates from broiler chickens in Tai'an, China.
The study identified mcr-1 as the primary cause of colistin resistance in E. coli isolates from broiler chickens in Tai'an, China, with high prevalence of multidrug resistance involving genes like bla TEM, bla CTX-M, aphA3, tetA, tetB, tetC, sul1, and sul2.
Research Note: Longitudinal monitoring of chicken houses in a commercial layer farm for antimicrobial resistance in Escherichia coli with special reference to plasmid-mediated quinolone resistance.
The study identified qnrS1, qnrS2, and qnrS13 genes as plasmid-mediated quinolone resistance genes in E. coli isolates from a commercial layer farm. Additionally, blaTEM, aadA, tetA, and dfrA1 genes were found to confer resistance to ampicillin, dihydrostreptomycin, oxytetracycline, and trimethoprim, respectively.
Functional metagenomics reveals antibiotic resistance determinants in dairy-associated microbial communities
The study identified several antibiotic resistance (AR) determinants in dairy products and processing environments, including genes conferring resistance to beta-lactams, tetracyclines, glycopeptides, macrolides, and streptogramins. Notably, Lactococcus lactis was found to be a significant reservoir of multidrug-resistant genes.
Population structure and antimicrobial resistance patterns of Salmonella Typhi isolates in urban Dhaka, Bangladesh from 2004 to 2016.
Dominant resistance and negative epistasis can limit the co-selection of de novo resistance mutations and antibiotic resistance genes.
The study identifies negative epistasis between the tetracycline efflux pump TetA and mutations in the nuo genes, which affects aminoglycoside resistance. It also characterizes the roles of various antibiotic resistance genes (ARGs) such as blaTEM-219, floR, qnrS1, and tetA in resistance to different antibiotics.
Genotypic characterization of multiple drug resistant Escherichia coli isolates from a pediatric cancer hospital in Egypt.
The study identified multiple drug-resistant Escherichia coli isolates from a pediatric cancer hospital in Egypt, highlighting the prevalence of various antimicrobial resistance genes such as TEM-220, NDM-11, aph(6)-Id, sul2, and others, indicating a significant threat to immunocompromised patients.
Molecular Detection of Multidrug Resistant Salmonella Species Isolated from Broiler Farm in Bangladesh.
The study identified multidrug-resistant Salmonella enterica serovar Typhimurium isolates from broiler farms in Bangladesh, carrying resistance genes tetA, floR, blaTEM-1, aadA1, and class 1 integron gene intl1.
Antimicrobial Resistance in Farm Animals in Brazil: An Update Overview.
The review highlights the prevalence of antimicrobial resistance in farm animals in Brazil, particularly in Salmonella, E. coli, and Campylobacter. Key resistance genes identified include blaCTX-M-2 and blaTEM-1, which confer resistance to beta-lactam antibiotics.
Detection of antibiotic-resistant bacteria and their resistance genes from houseflies.
The study identified antibiotic-resistant bacteria from houseflies, including S. aureus, Salmonella spp., and E. coli, carrying resistance genes mecA, tetA, tetB, and mcr-3.
Whole Genome Sequencing and Characteristics of mcr-1-Harboring Plasmids of Porcine Escherichia coli Isolates Belonging to the High-Risk Clone O25b:H4-ST131 Clade B.
The study identified the mcr-1.1 gene in five porcine E. coli isolates, which confers resistance to colistin. The gene was found on various plasmids, including IncF, IncX4, and IncHI2, highlighting the role of mobile genetic elements in the spread of colistin resistance.
Systematic Evaluation of Whole Genome Sequence-Based Predictions of Salmonella Serotype and Antimicrobial Resistance.
The study evaluated the performance of various bioinformatics tools for predicting antimicrobial resistance (AMR) and serotypes of Salmonella enterica using whole-genome sequencing (WGS). It identified several AMR genes and mutations associated with resistance to various antibiotics.
Antimicrobial resistance of Escherichia coli isolated from retail foods in northern Xinjiang, China.
The study identified various antimicrobial resistance genes in Escherichia coli isolates from retail foods in northern Xinjiang, China, including tetA, tetB, blaOXA, blaTEM, floR, sul1, sul2, aadAla, aadB, strA, and strB. These genes conferred resistance to tetracycline, beta-lactams, chloramphenicol, sulfonamides, and streptomycin.
Antimicrobial resistance of Escherichia coli isolated from retail foods in northern Xinjiang, China.
The study identified various antimicrobial resistance genes in Escherichia coli isolates from retail foods in northern Xinjiang, China, including tetA, tetB, blaOXA, blaTEM, floR, sul1, sul2, aadAla, aadB, strA, and strB. These genes conferred resistance to tetracycline, beta-lactams, chloramphenicol, sulfonamides, and streptomycin.
Evolutionary innovation using EDGE, a system for localized elevated mutagenesis.
The study demonstrates that targeted mutagenesis using the EDGE system can lead to the evolution of resistance to tigecycline through a point mutation in the tetA gene, specifically I235V.
Co-occurrence of mcr-1, mcr-3, mcr-7 and clinically relevant antimicrobial resistance genes in environmental and fecal samples.
The study identified the co-occurrence of mcr-1, mcr-3, mcr-7.1, and various clinically relevant antimicrobial resistance genes in environmental and fecal samples from a Brazilian zoo, highlighting the potential reservoir of these genes in zoological environments.
Klebsiella pneumoniae carriage in low-income countries: antimicrobial resistance, genomic diversity and risk factors.
The study identified various AMR genes and mutations in Klebsiella pneumoniae isolates from pregnant women in low-income countries, highlighting the prevalence of multidrug-resistant strains and the role of environmental factors in their carriage.
Non-antibiotic pharmaceuticals enhance the transmission of exogenous antibiotic resistance genes through bacterial transformation.
Non-antibiotic pharmaceuticals enhance the transformation frequency of exogenous antibiotic resistance genes (ARGs) in Acinetobacter baylyi, particularly those encoding resistance to ampicillin (blaTEM-1) and tetracycline (tetA).
A broad-spectrum antibiotic adjuvant reverses multidrug-resistant Gram-negative pathogens.
The study identifies several AMR genes, including blaNDM-5, mcr-1, tetA, mdfA, oqxAB, arr-2, aph(4), aac(3)-IV, and fosA3, which are associated with resistance to various antibiotics. These genes were found in a multidrug-resistant E. coli isolate and were shown to be targeted by the antibiotic adjuvant SLAP-S25, enhancing the efficacy of antibiotics against MDR Gram-negative pathogens.
Prevalence and distribution of antimicrobial resistance determinants of Escherichia coli isolates obtained from meat in South Africa.
The study identified several AMR genes in E. coli isolates from meat in South Africa, including aadA, strA, aph(3)-Ia, aph(3)-IIa, aac(3)-IIa, blaTEM, blaZ, ampC, cat1, cat2, cmlA1, sul1, sul2, tetA, tetB, tetC, tetD, and tetM, which confer resistance to various antibiotics such as streptomycin, kanamycin, neomycin, gentamicin, amoxicillin, ampicillin, chloramphenicol, cotrimoxazole, and tetracycline.
Comparative analysis of multidrug resistance plasmids and genetic background of CTX-M-producing Escherichia coli recovered from captive wild animals.
The study identifies multiple AMR genes and mutations in MDR E. coli strains from captive wild animals, highlighting the presence of CTX-M-8 and CTX-M-65 beta-lactamases, along with various other resistance mechanisms such as aminoglycoside, tetracycline, and fluoroquinolone resistance genes, as well as mutations in quinolone resistance-determining regions.
Whole Genome Sequencing Analysis of Porcine Faecal Commensal Escherichia coli Carrying Class 1 Integrons from Sows and Their Offspring.
The study identified multiple antimicrobial resistance genes in porcine faecal commensal E. coli, including blaTEM-1, strA, strB, tetA, dfrA12, aadA1, aadA2, cmlA, aph(3')-Ia, sul2, and sul3, which confer resistance to beta-lactams, streptomycin, tetracyclines, trimethoprim, aminoglycosides, chloramphenicol, neomycin, kanamycin, and sulfonamides.
Molecular identification and antibiotic resistance profiling of Salmonella species isolated from chickens in eastern Turkey.
The study identified the presence of antibiotic resistance genes sul1, tetA, and blaTEM in Salmonella isolates from chickens in eastern Turkey, with sul1 being the most frequently detected gene.
Detection of class 1 integron-associated gene cassettes and tetracycline resistance genes in Escherichia coli isolated from ready to eat vegetables.
The study identified the tetA gene and the dfrA7 gene cassette in tetracycline-resistant E. coli isolates from ready-to-eat vegetables, indicating resistance to tetracycline, streptomycin, kanamycin, and trimethoprim.
Antimicrobial Resistance, Virulence Genes, and Biofilm Formation Capacity Among Enterococcus species From Yaks in Aba Tibetan Autonomous Prefecture, China.
The study identified multiple antimicrobial resistance (AMR) genes in Enterococcus species isolated from yaks, including ermA, ermB, tetA, tetB, tetM, tetL, cat, optrA, and poxtA. These genes conferred resistance to various antibiotics such as erythromycin, tetracycline, chloramphenicol, and linezolid. Additionally, a high prevalence of multidrug-resistant (MDR) Enterococcus strains was observed.
Detection of Extended-Spectrum β-Lactamases (ESBL) Producing Enterobacteriaceae from Fish Trapped in the Lagoon Area of Bizerte, Tunisia.
The study identified several β-lactamase genes (bla CTX-M-1, bla CTX-M-15, bla CTX-M-9, bla OXA-1, and bla TEM-1-a) and other resistance genes (sul1, sul2, tetA, aac(6')-Ib-cr, qnrA, and qnrB) in ESBL-producing Enterobacteriaceae isolated from fish in the Bizerte lagoon, highlighting the presence of multidrug-resistant bacteria in aquatic environments.
Molecular characteristics of fluoroquinolone-resistant avian pathogenic Escherichia coli isolated from broiler chickens.
The study identified several AMR genes and mutations in fluoroquinolone-resistant avian pathogenic Escherichia coli (APEC) isolates, including qnrA, qnrS, blaCTX-1, blaCTX-15, blaTEM-1, aac(3)-II, tetA, sul1, sul2, and catA1, along with mutations in gyrA and parC that confer fluoroquinolone resistance.
Antimicrobial Resistance in Swine Fecal Specimens Across Different Farm Management Systems.
The study identified several AMR genes associated with different antimicrobial classes in swine fecal samples from farms with varying antimicrobial usage levels. These genes included beta-lactamases, aminoglycoside modifying enzymes, fluoroquinolone resistance genes, macrolide resistance markers, polymyxin resistance genes, phenicol resistance genes, and trimethoprim resistance genes.
Isolation and Comparative Genomic Analysis of Reuterin-Producing Lactobacillus reuteri From the Chicken Gastrointestinal Tract.
The study identified ermB and tetW genes in L. reuteri strains from chicken GIT, which confer resistance to erythromycin and tetracycline, respectively. These genes were validated through PCR and sequencing.
Occurrence, Virulence and Antimicrobial Resistance-Associated Markers in Campylobacter Species Isolated from Retail Fresh Milk and Water Samples in Two District Municipalities in the Eastern Cape Province, South Africa.
The study identified several antimicrobial resistance genes in Campylobacter species isolated from retail fresh milk and water samples, including catII, tetA, tetB, tetM, ermB, gyrA, ampC, and aac(3)-IIa-(aacC2). These genes were associated with resistance to chloramphenicol, tetracycline, erythromycin, gentamicin, and ampicillin.
Comparison of antimicrobial resistant genes in chicken gut microbiome grown on organic and conventional diet.
The study identified various antimicrobial resistance genes in the gut microbiome of chickens raised on organic and conventional diets, including beta-lactamases, multidrug efflux systems, aminoglycoside modifying enzymes, and tetracycline resistance genes. These genes were found to be more prevalent in conventional diet samples under higher antibiotic concentrations.
Prevalence of diversified antibiotic resistant bacteria within sanitation related facilities of human populated workplaces in Abbottabad.
The study identified tetracycline resistance genes (tetA and tetM) in Pseudomonas putida strains isolated from sanitation facilities in Abbottabad, indicating plasmid-mediated resistance.
F Plasmids Are the Major Carriers of Antibiotic Resistance Genes in Human-Associated Commensal Escherichia coli.
The study identifies various antibiotic resistance genes in commensal E. coli isolates, highlighting the prevalence of resistance genes on F plasmids and the role of mobile genetic elements in their dissemination.
Antibiotic Susceptibility Testing (AST) Reports: A Basis for Environmental/Epidemiological Surveillance and Infection Control Amongst Environmental Vibrio cholerae.
The study identified various antibiotic resistance genes in Vibrio cholerae isolates, including blaTEM, NDM-1, AmpC, and ESBL, indicating multidrug resistance in environmental V. cholerae.
First Genomic Characterization of bla(VIM-1) and mcr-9-Coharbouring Enterobacter hormaechei Isolated from Food of Animal Origin.
The study reports the first genomic characterization of a multidrug-resistant Enterobacter hormaechei isolate coharboring bla(VIM-1) and mcr-9 genes from food of animal origin. The isolate was resistant to carbapenems and other antibiotics, but susceptible to colistin. The bla(VIM-1) and mcr-9 genes were located on the same IncHI2 plasmid, along with other resistance genes.
Profiling Virulence and Antimicrobial Resistance Markers of Enterovirulent Escherichia Coli from Fecal Isolates of Adult Patients with Enteric Infections in West Cameroon.
The study identified several AMR genes and mutations in enterovirulent E. coli isolates from adult patients in Cameroon, including blaTEM, blaOxa, cat1, cat2, tetB, tetA, tetG, sul2, and dfrA12, along with mutations in gyrA and parC contributing to quinolone resistance.
Detection and Profiling of Antibiotic Resistance among Culturable Bacterial Isolates in Vended Food and Soil Samples.
The study identified several antibiotic resistance genes including Bla TEM, StrB, DfrA, TetA, and FloR in bacterial isolates from vended food and soil samples in Embu Town and Kangaru Market, Kenya.
The Role of Urban Wastewater in the Environmental Transmission of Antimicrobial Resistance: The Current Situation in Italy (2010-2019).
The study identified several AMR genes in urban wastewater treatment plants in Italy, including bla TEM-1, bla AmpC, bla CTX-M-15, bla KPC-3, bla SHV-1, tet A, sul II, erm B, qnr S, int I1, aad A2, dfr 17, aadA 5, aadA 10, sat 1, bla TEM, bla OXA, bla CTX, bla KPC, and tet W. These genes confer resistance to various antibiotics such as beta-lactams, tetracyclines, sulfonamides, macrolides, fluoroquinolones, and aminoglycosides.
Hospital Wastewater-Important Source of Multidrug Resistant Coliform Bacteria with ESBL-Production.
The study identifies several AMR genes, including bla TEM, bla CTX-M-2, bla CTX-M-8/25, tetA, and tetE, which are associated with multidrug resistance in coliform bacteria from hospital wastewater.
Occurrence of Antibiotic-Resistant Bacteria and Genes in Two Drinking Water Treatment and Distribution Systems in the North-West Province of South Africa.
The study identified several antibiotic resistance genes, including strA, strB, aadA, dfrB, bla CTX-M, and tetA, in heterotrophic bacteria from drinking water treatment and distribution systems in South Africa.
Isolation and Characterization of Multidrug-Resistant Escherichia coli and Salmonella spp. from Healthy and Diseased Turkeys.
The study identified the tetracycline resistance gene tetA in multidrug-resistant E. coli and Salmonella spp. isolated from turkeys, highlighting the prevalence of tetracycline resistance in these pathogens.
Genotypic antimicrobial resistance characterization of E. coli from dairy calves at high risk of respiratory disease administered enrofloxacin or tulathromycin.
The study identified several AMR genes and mutations in E. coli from dairy calves, including aac(6')Ib-cr, bla-CTX-M, bla-TEM, tetA, tetB, and gyrA mutations. These genes and mutations were associated with resistance to various antibiotics such as ciprofloxacin, ceftazidime, tetracycline, and others.
Snapshot Study of Whole Genome Sequences of Escherichia coli from Healthy Companion Animals, Livestock, Wildlife, Humans and Food in Italy.
The study identified multiple antimicrobial resistance genes (ARGs) and mutations in Escherichia coli isolates from various sources in Italy, highlighting the prevalence of resistance to tetracycline, sulfonamide, penicillin, fluoroquinolone, and colistin. Key genes included tetA, sul2, blaTEM-1b, mcr-1, qnrS1, and others, along with mutations in gyrA, parC, parE, and pmrB.
Aeromonas hydrophila RIT668 and Citrobacter portucalensis RIT669-Potential Zoonotic Pathogens Isolated from Spotted Turtles.
Aeromonas hydrophila RIT668 and Citrobacter portucalensis RIT669 were found to be resistant to several antibiotics including gentamicin, tetracycline, doxycycline, kanamycin, streptomycin, tobramycin, novobiocin, and erythromycin, but susceptible to neomycin and cotrimoxazole. They exhibited multidrug resistance in the planktonic phase and weak biofilm eradication even with neomycin and cotrimoxazole.
Molecular Epidemiology of Antibiotic-Resistant Escherichia coli from Farm-To-Fork in Intensive Poultry Production in KwaZulu-Natal, South Africa.
The study identified the presence of bla CTX-M, sul1, tetA, and tetB genes in Escherichia coli isolates from various stages of the farm-to-fork continuum in intensive poultry production in South Africa.
Occurrence, identification, and antibiogram signatures of selected Enterobacteriaceae from Tsomo and Tyhume rivers in the Eastern Cape Province, Republic of South Africa.
The study identified various beta-lactamase genes (bla TEM, bla CTX-M, bla SHV, bla OXA-1-like, bla PER, bla VIM, bla IMP, bla KPC, bla GES, bla OXA-48-like), plasmid-mediated AmpC beta-lactamase genes (bla EBC, bla ACC, bla FOX, bla CIT), tetracycline resistance genes (tetA, tetB, tetD, tetM), chloramphenicol resistance gene (catII), and sulfonamide resistance gene (sulII) in Enterobacteriaceae isolates from Tsomo and Tyhume rivers.
Pathotyping and Antibiotic Resistance Profiling of Escherichia coli Isolates from Children with Acute Diarrhea in Amatole District Municipality of Eastern Cape, South Africa.
The study identified high levels of antibiotic resistance in E. coli isolates from children with acute diarrhea, particularly to ampicillin, chloramphenicol, trimethoprim-sulfamethoxazole, and tetracycline. The resistance genes catA1 and tetA were found in 94% and 89% of the isolates, respectively.
Genomic Analysis of Aeromonas veronii C198, a Novel Mcr-3.41-Harboring Isolate from a Patient with Septicemia in Thailand.
The study identified a novel mcr-3.41 gene in the Aeromonas veronii isolate C198, which confers resistance to colistin. Additionally, other resistance genes such as bla_cphA3, bla_OXA-12, tetA, adeF, and rsmA were found to contribute to resistance against various antibiotics.
Isolation and molecular characterization of multidrug-resistant Escherichia coli from chicken meat.
The study identified multiple antibiotic resistance genes in multidrug-resistant E. coli isolates from chicken meat, including tetA, sul1, aadA1, ereA, aac-3-IV, cmlA, catA1, SHV, and CITM, highlighting the prevalence of resistance to various antibiotics such as tetracycline, sulfonamide, streptomycin, erythromycin, gentamicin, chloramphenicol, and beta-lactams.
Genomic Characteristics of Colistin-Resistant Salmonella enterica subsp. enterica Serovar Infantis from Poultry Farms in the Republic of Serbia.
The study identified the fosfomycin resistance gene fosA7 and the vgaA gene in Salmonella enterica subsp. enterica serovar Infantis isolates from poultry farms in Serbia. Mutations in the pmrB gene were associated with colistin resistance.
Circulation of oxytetracycline- and ciprofloxacin-resistant commensal Escherichia coli strains in broiler chickens and farm environments, Bangladesh.
The study identified the tetA gene as the primary contributor to oxytetracycline resistance in commensal E. coli strains from broiler chickens and farm environments in Bangladesh. Additionally, 78.4% of the isolates showed resistance to ciprofloxacin, though no specific mutations were characterized.
Isolation of multidrug-resistant Escherichia coli, Staphylococcus spp., and Streptococcus spp. from dogs in Chattogram Metropolitan Area, Bangladesh.
The study identified multidrug-resistant Escherichia coli, Staphylococcus spp., and Streptococcus spp. from dogs in Bangladesh, highlighting the presence of resistance genes such as bla TEM, bla CTX-M, tet A, and Sul- II.
Colistin-resistant Enterobacter kobei carrying mcr-9.1 and bla(CTX-M-15) infecting a critically endangered franciscana dolphin (Pontoporia blainvillei), Brazil.
The study reports the emergence of the mcr-9.1 gene in a colistin-resistant Enterobacter kobei strain isolated from a critically endangered franciscana dolphin in Brazil, along with various other AMR genes.
Colistin Dependence in Extensively Drug-Resistant Acinetobacter baumannii Strain Is Associated with ISAjo2 and ISAba13 Insertions and Multiple Cellular Responses.
The study identifies the disruption of lpxA, mlaD, and pldA genes by IS Ajo2 and IS Aba13 insertions in colistin-dependent A. baumannii, leading to lipid A deficiency and colistin dependence.
Multidrug-Resistant Listeria Species Shows Abundance in Environmental Waters of a Key District Municipality in South Africa.
The study identified multiple antimicrobial resistance genes in Listeria species isolated from environmental waters, including sulI, tetA, blaTEM, and blaCIT, which confer resistance to sulfonamides, tetracyclines, and beta-lactams.
Antimicrobial Resistance in Escherichia coli Strains Isolated from Humans and Pet Animals.
The study identifies several AMR genes in E. coli strains isolated from humans and pet animals, including blaTEM, qnrS1, qnrB1, blaCMY-2, blaCMY-59, tetA, tetB, sul1, sul2, and sul3, which confer resistance to various antibiotics such as beta-lactams, quinolones, tetracyclines, and sulfonamides.
Molecular characterisation of extended-spectrum ß-lactamase producing Escherichia coli in wild birds and cattle, Ibadan, Nigeria.
The study identified various AMR genes in ESBL-producing E. coli from wild birds and cattle in Nigeria, including bla CTX-M1/15, bla CTX-M9, strB, sul2, tetA, and others. These genes were associated with resistance to multiple antibiotics, highlighting the potential for inter-species transmission of AMR bacteria.
Study on Bacteria Isolates and Antimicrobial Resistance in Wildlife in Sicily, Southern Italy.
The study identified the presence of blaTEM, sulII, and tetA genes in a limited number of bacterial isolates from wildlife in Sicily, indicating a low prevalence of antimicrobial resistance genes in the studied population.
Higher prevalence of multidrug-resistant extended-spectrum β-lactamases producing Escherichia coli in unorganized pig farms compared to organized pig farms in Mizoram, India.
The study identified several AMR genes, including bla TEM, bla CTX-M, bla CMY, tetA, tetB, sul1, sul2, aadA, and dfrIa, in multidrug-resistant E. coli isolates from both organized and unorganized pig farms in Mizoram, India.
Characterization of Enterococci- and ESBL-Producing Escherichia coli Isolated from Milk of Bovides with Mastitis in Egypt.
The study identified several AMR genes in Enterococcus and ESBL-producing E. coli isolates from bovine mastitis cases in Egypt, including erm(B), tetL, aac-aphD, vanA, and vanB.
A Preliminary Study: Antibiotic Resistance of Escherichia coli and Staphylococcus aureus from the Meat and Feces of Various South African Wildlife Species.
The study identified antibiotic resistance genes in Escherichia coli and Staphylococcus aureus from wildlife meat and feces, including blaCMY, aadA, sul1, sul2, tetA, tetB, tetK, tetL, tetM, vanA, vanB, and blaZ, which conferred resistance to ampicillin, streptomycin, sulfonamides, tetracycline, vancomycin, and penicillin.
Effects of in ovo probiotic administration on the incidence of avian pathogenic Escherichia coli in broilers and an evaluation on its virulence and antimicrobial resistance properties.
The study identified various antimicrobial resistance genes in APEC isolates, including blaTEM, aac(3)-VIa, aac(3)-VIb, aadA, tetA, tetB, dfr7, qacEΔ, qnr, sul1, intl1, arsC, and merA. These genes conferred resistance to multiple antibiotics such as beta-lactams, aminoglycosides, tetracyclines, quinolones, sulfonamides, and heavy metals.
Endophytic Lifestyle of Global Clones of Extended-Spectrum β-Lactamase-Producing Priority Pathogens in Fresh Vegetables: a Trojan Horse Strategy Favoring Human Colonization?
The study identifies multiple AMR genes in endophytic ESBL-producing Enterobacterales isolated from fresh vegetables, highlighting their potential role in the spread of antibiotic resistance.
Emerging carbapenem-resistant Klebsiella pneumoniae sequence type 16 causing multiple outbreaks in a tertiary hospital in southern Vietnam.
The study identifies carbapenem-resistant Klebsiella pneumoniae sequence type 16 causing multiple outbreaks in a hospital in Vietnam. Key AMR genes include blaOXA-181, blaOXA-48, and mutations in gyrA and parC contributing to fluoroquinolone resistance. Colistin resistance was due to disruption of the mgrB gene by an IS L3-like element.
Comparative genomics of Flavobacterium columnare unveils novel insights in virulence and antimicrobial resistance mechanisms.
The study identified a tetracycline resistance gene, tetA, in a highly virulent Flavobacterium columnare carp isolate, and a mutation in the gyrase gene gyrA associated with quinolone resistance in a low-virulent isolate.
High Prevalence of Drug Resistance and Class 1 Integrons in Escherichia coli Isolated From River Yamuna, India: A Serious Public Health Risk.
The study identified several AMR genes including bla TEM-1, bla CTX-M-15, tetA, qnrS1, strA-strB, and armA in E. coli isolates from the Yamuna River, highlighting the significant public health risk posed by these resistant strains.
Utility of whole-genome sequencing during an investigation of multiple foodborne outbreaks of Shigella sonnei.
The study identified multiple antimicrobial resistance genes in the Shigella sonnei outbreak strain, including blaCTX-M-15, qnrS1, strA, strB, dfrA1, tetA, and sul2, which conferred resistance to various antibiotics such as ceftazidime, ciprofloxacin, streptomycin, trimethoprim, tetracycline, and sulfamethoxazole.
Open Waste Canals as Potential Sources of Antimicrobial Resistance Genes in Aerosols in Urban Kanpur, India.
The study identified the presence of antimicrobial resistance genes (ARGs) including intI1, tetA, blaTEM, and qnrB in aerosols near open wastewater canals (OWCs) in Kanpur, India, highlighting the potential role of these environments in the spread of ARGs.
A Comparative Analysis of Aquatic and Polyethylene-Associated Antibiotic-Resistant Microbiota in the Mediterranean Sea.
The study found that polyethylene (PE) waste samples from both seawater and freshwater contained a higher number of antibiotic resistance genes (ARGs) compared to the corresponding water samples, highlighting the role of PE as a carrier of ARGs in the marine environment.
Tetracycline-Resistant Bacteria Selected from Water and Zebrafish after Antibiotic Exposure.
The study identifies the tetA gene as a tetracycline resistance gene in Pseudomonas and Stenotrophomonas isolates from zebrafish and water samples after exposure to oxytetracycline.
Antimicrobial Resistance Profile and ExPEC Virulence Potential in Commensal Escherichia coli of Multiple Sources.
The study identified several AMR genes, including blaCTX-M, mcr-1, and qnrS1, which confer resistance to cephalosporins, colistin, and fluoroquinolones, respectively, in commensal E. coli from various sources.
Genomic diversity and molecular epidemiology of Pasteurella multocida.
This study identified several antimicrobial resistance genes in Pasteurella multocida, including aminoglycoside, beta-lactam, tetracycline, macrolide, and sulfonamide resistance genes, highlighting the diverse resistance mechanisms present in this pathogen.
Antimicrobial drug resistant non-typhoidal Salmonella enterica in commercial poultry value chain in Chitwan, Nepal.
The study identified high prevalence of antimicrobial resistance in non-typhoidal Salmonella enterica isolates from poultry and environmental samples in Nepal, with tetA, QnrS, mefA, and VIM-1 genes detected.
Isolation and detection of antibiotics resistance genes of Escherichia coli from broiler farms in Sukabumi, Indonesia.
The study identified four antibiotic resistance genes in Escherichia coli isolates from broiler farms in Sukabumi, Indonesia: tetA, blaTEM, gyrA, and ermB. These genes conferred resistance to tetracycline, oxytetracycline, ampicillin, nalidixic acid, ciprofloxacin, enrofloxacin, and erythromycin.
Virulence and Antimicrobial Resistance Profiles of Salmonella enterica Serovars Isolated from Chicken at Wet Markets in Dhaka, Bangladesh.
The study identified multiple antimicrobial resistance genes, including blaTEM, tetA, sul1, and strA/B, in Salmonella enterica serovars isolated from chicken at wet markets in Dhaka, Bangladesh. These genes conferred resistance to various antibiotics such as ampicillin, tetracycline, sulfamethoxazole-trimethoprim, and streptomycin.
Comparative Characteristics and Zoonotic Potential of Avian Pathogenic Escherichia coli (APEC) Isolates from Chicken and Duck in South Korea.
The study identified several antimicrobial resistance genes in APEC isolates from chickens and ducks in South Korea, including mcr-1, blaTEM, blaCTX-M group I, blaCTX-M group IV, mphA, cat, floR, cmlA, strA-B, aadA, sul1, sul2, tetA, and tetB. These genes conferred resistance to various antibiotics such as colistin, ampicillin, azithromycin, chloramphenicol, streptomycin, sulfisoxazole, and tetracycline. The study also highlighted the zoonotic potential of certain APEC isolates, particularly those belonging to phylogenetic group B2.
Chlorine disinfection facilitates natural transformation through ROS-mediated oxidative stress.
The study shows that chlorine-based disinfectants can enhance the transformation of plasmid-encoded antibiotic resistance genes (ARGs) by increasing reactive oxygen species (ROS) and cell membrane permeability in Acinetobacter baylyi ADP1. The genes bla TEM-1 and tetA were experimentally validated to confer resistance to ampicillin and tetracycline, respectively.
Antibiotic resistance, antimicrobial residues, and bacterial community diversity in pasture-raised poultry, swine, and beef cattle manures.
The study identified the presence of antibiotic resistance genes Sul 1 and Tet A in the feces of pasture-raised poultry, swine, and beef cattle, highlighting the prevalence of these genes even in the absence of routine antibiotic use.
Multidrug-resistant Klebsiella pneumoniae harboring extended spectrum β-lactamase encoding genes isolated from human septicemias.
The study identified multiple beta-lactamase genes including bla CTX-M-15, bla SHV-1, bla SHV-11, bla SHV-27, bla SHV-106, and bla TEM, along with carbapenemase genes bla KPC2/3 and bla OXA-48, contributing to multidrug resistance in Klebsiella pneumoniae isolates from human septicemias.
atpD gene sequencing, multidrug resistance traits, virulence-determinants, and antimicrobial resistance genes of emerging XDR and MDR-Proteus mirabilis.
The study identified multiple antimicrobial resistance genes in XDR and MDR-Proteus mirabilis isolates from ducks, including blaTEM, blaOXA-1, blaCTX-M, tetA, sul1, blaNDM-1, and blaKPC. These genes confer resistance to various antibiotic classes such as penicillins, cephalosporins, tetracyclines, sulfonamides, and carbapenems.
Biosolids as a Source of Antibiotic Resistance Plasmids for Commensal and Pathogenic Bacteria.
Six unique resistance plasmids were identified that can transfer to Salmonella typhimurium, Klebsiella aerogenes, and E. coli, carrying 3-6 antibiotic resistance genes conferring resistance to 2-4 antibiotic classes.
Multidrug-resistant bacteria as intestinal colonizers and evolution of intestinal colonization in healthy university students in Portugal.
The study identified various AMR genes in commensal E. coli isolates from healthy university students in Portugal, including bla TEM, tetA, tetB, sul1, sul2, sul3, parC, and gyrA, indicating the presence of multidrug-resistant bacteria in the intestinal microbiota.
Escherichia coli Antibiotic Resistance Patterns from Co-Grazing and Non-Co-Grazing Livestock and Wildlife Species from Two Farms in the Western Cape, South Africa.
The study identified several antibiotic resistance genes in E. coli isolates from livestock and wildlife, including bla CMY, aad A1, sul 1, sul 2, tet A, and tet B, which conferred resistance to ampicillin, streptomycin, sulfonamides, and tetracycline. The research highlights differences in resistance patterns between co-grazing and non-co-grazing animals.
Diversity of Plasmids and Genes Encoding Resistance to Extended-Spectrum β-Lactamase in Escherichia coli from Different Animal Sources.
The study identified various AMR genes and mutations in E. coli isolates from different animal sources, highlighting the presence of ESBL genes such as bla CTX-M-15, bla TEM-1B, and bla CMY-28, as well as mutations in parC and gyrA that confer resistance to fluoroquinolones.
Subclinical Mastitis in Selected Bovine Dairy Herds in North Upper Egypt: Assessment of Prevalence, Causative Bacterial Pathogens, Antimicrobial Resistance and Virulence-Associated Genes.
The study identified several AMR genes in bacterial isolates from subclinical mastitis cases in bovine dairy herds in North Upper Egypt, including mecA, blaZ, icaD, aph(3')-IIIa, vanC-2/3as, hyl, cfb, tetA, sul1, fimH, and tsh. These genes were detected through PCR and are associated with resistance to methicillin, beta-lactams, aminoglycosides, vancomycin, tetracyclines, and sulphonamides.
Isolation, Antimicrobial Resistance Phenotypes, and Virulence Genes of Bordetella bronchiseptica From Pigs in China, 2018-2020.
The study identified several antimicrobial resistance genes in Bordetella bronchiseptica isolates from pigs in China, including aac(3)-IV, aac6'-Ib, rmtA, blaTEM, blaSHV, oqxB, and tetA. These genes confer resistance to various antibiotics such as aminoglycosides, beta-lactams, fluoroquinolones, and tetracyclines.
Antibiotic Resistant and Biofilm-Associated Escherichia coli Isolates from Diarrheic and Healthy Dogs.
The study identified several AMR genes in E. coli isolates from healthy and diarrheic dogs, including blaTEM-1, qnrB, qnrS, aac(6')-Ib-cr, tetA, tetB, dfrA, sul1, sul2, int1, and tn3. These genes confer resistance to various antibiotics such as ampicillin, ciprofloxacin, tetracycline, trimethoprim, and sulfonamide.
Molecular Characterization and Survive Abilities of Salmonella Heidelberg Strains of Poultry Origin in Brazil.
The study identified the presence of bla CTX-M and bla CMY-2 genes in Salmonella Heidelberg strains, which confer resistance to various beta-lactam antibiotics. These genes were detected in 80% of the strains, highlighting the prevalence of multidrug resistance in poultry-origin Salmonella Heidelberg.
Foodborne Pathogenic Vibrios: Antimicrobial Resistance.
The paper discusses the presence of various antibiotic resistance genes in Vibrio species, including strB, sul2, tetA, blaTEM, qnrA, ermB, floR, aac(3)-IIa, blaNDM-1, blaCMY, blaP1, catB3, and others, which confer resistance to antibiotics such as streptomycin, sulfamethoxazole, tetracycline, ampicillin, fluoroquinolones, erythromycin, florfenicol, gentamicin, carbapenems, chloramphenicol, and trimethoprim.
Detection of bla(TEM), bla(CTX-M), bla(CMY), and bla(SHV) Genes Among Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Isolated from Migratory Birds Travelling to Bangladesh.
The study identified bla(TEM), bla(CTX-M), bla(CMY), and bla(SHV) genes in extended-spectrum beta-lactamase-producing Escherichia coli isolated from migratory birds in Bangladesh, highlighting the role of migratory birds as potential carriers of antibiotic resistance genes.
Prevalence and mechanisms of antibiotic resistance in Escherichia coli isolated from mastitic dairy cattle in Canada.
The study identified several AMR genes in E. coli isolates from bovine mastitis, including beta-lactamases (blaTEM-1, blaCARB-3, blaCMY-59), tetracycline resistance genes (tetA, tetB, tetC), aminoglycoside resistance genes (aph(3')-Ia, aph(3'')-Ib, aph(6)-Id, aadA2), and multidrug efflux pump genes (acrA, acrB, acrD, tolC, baeR, emrA, emrB).
Genomic Epidemiology of Multidrug-Resistant Nontyphoidal Salmonella in Young Children Hospitalized for Gastroenteritis.
Emergence and Clonal Spread of CTX-M-65-Producing Escherichia coli From Retail Meat in Portugal.
The study identifies the blaCTX-M-65 gene in four multidrug-resistant Escherichia coli isolates from retail meat in Portugal, highlighting its chromosomal location and association with various resistance mechanisms.
Characterization of Tigecycline Resistance Among Tigecycline Non-susceptible Klebsiella pneumoniae Isolates From Humans, Food-Producing Animals, and in vitro Selection Assay.
The study identifies mutations in ramR and acrR genes that contribute to tigecycline resistance in Klebsiella pneumoniae isolates from humans, food animals, and in vitro selection. Additionally, inactivation of mgrB was found to be associated with colistin resistance.
Genomic insights into the diversity, virulence and resistance of Klebsiella pneumoniae extensively drug resistant clinical isolates.
The study identified various beta-lactamase genes, including blaSHV-11, blaKPC-2, and blaNDM-1, along with qnrS1, aadA1, dfrA1, and sul1, which contribute to multidrug resistance in extensively drug-resistant Klebsiella pneumoniae isolates.
Machine Learning Prediction of Resistance to Subinhibitory Antimicrobial Concentrations from Escherichia coli Genomes.
The study identifies several known AMR genes, including aacA-aphD, cat, dhfrI, dhfrV, neo, tetA, and tnpA, which are associated with resistance to kanamycin, chloramphenicol, trimethoprim, and ceftriaxone. These genes were validated through machine learning predictions of growth under subinhibitory antimicrobial concentrations.
Antimicrobial Resistance of Non-Typhoid Salmonella in Meat and Meat Products.
The study highlights the prevalence of antimicrobial resistance in non-typhoid Salmonella isolates from meat and meat products, emphasizing the resistance patterns to antibiotics such as tetracycline, sulfonamides, ampicillin, and streptomycin. It identifies Enteritidis and Typhimurium as the most common serovars with significant resistance levels.
Detection of mobile genetic elements in multidrug-resistant Klebsiella pneumoniae isolated from different infection sites in Hamadan, west of Iran.
The study identified the presence of sulI, sulII, tetA, tetB, intI, and intII genes in multidrug-resistant Klebsiella pneumoniae isolates, highlighting the role of these mobile genetic elements in the spread of antibiotic resistance.
Antibiotic Resistance and Virulence Profiles of Escherichia coli Strains Isolated from Wild Birds in Poland.
The study identified several AMR genes in E. coli strains isolated from wild birds in Poland, including blaTEM, aphA1, sul2, and tetA, which confer resistance to ampicillin, kanamycin, trimethoprim/sulfamethoxazole, and tetracycline, respectively.
Artificial sweeteners stimulate horizontal transfer of extracellular antibiotic resistance genes through natural transformation.
Artificial sweeteners enhance the horizontal transfer of extracellular antibiotic resistance genes (ARGs) through natural transformation in Acinetobacter baylyi ADP1, Bacillus subtilis, and mice fecal microbiome. The study identifies that the plasmid pWH1266, carrying blaTEM-1 and tetA, is efficiently taken up by competent cells, leading to increased resistance to ampicillin and tetracycline.
Antimicrobial Resistance and Whole-Genome Characterisation of High-Level Ciprofloxacin-Resistant Salmonella Enterica Serovar Kentucky ST 198 Strains Isolated from Human in Poland.
The study identified several AMR genes and mutations in high-level ciprofloxacin-resistant Salmonella Enterica serovar Kentucky ST198 strains isolated from humans in Poland, including blaTEM-1B, qnrS1, aac(3)-Id, aac(3)-IId, aac(6')-Iaa, aac(6')-Iid, aph(3")-Ib, aph(3")-Id, aadA1, sul1, dfrA1, and tetA, along with mutations in gyrA and parC that confer resistance to quinolones and beta-lactams.
Genomic Characterization of Multidrug-Resistant Salmonella Serovars Derby and Rissen From the Pig Value Chain in Vietnam.
The study identified multiple antimicrobial resistance genes in Salmonella serovars Derby and Rissen from Vietnam, highlighting the presence of multidrug-resistant strains along the pig value chain.
Discerning the Antimicrobial Resistance, Virulence, and Phylogenetic Relatedness of Salmonella Isolates Across the Human, Poultry, and Food Materials Sources in Malaysia.
The study identified several AMR genes in Salmonella Enteritidis isolates from Malaysia, including aac(6')-ly, blaCMY-2, blaTEM-1, blaTEM-33, blaTEM-4, dfrA14, dfrA15, floR, qnrS1, qnrD1, sul1, sul2, strA, strB, tetA, and tetC. These genes conferred resistance to various antibiotics such as gentamicin, ampicillin, chloramphenicol, ciprofloxacin, sulfamethazine/trimethoprim, and tetracycline.
Antimicrobial resistance and genomic characterization of Salmonella Dublin isolates in cattle from the United States.
The study characterized multidrug-resistant Salmonella Dublin isolates from cattle in the United States, identifying key AMR genes such as sul2, tetA, aph(6)-Id, aph(3''-Ib, floR, and blaCMY-2, along with quinolone resistance mutations in gyrA.
Prevalence, antibiotic susceptibility, and presence of drug resistance genes in Aeromonas spp. isolated from freshwater fish in Kelantan and Terengganu states, Malaysia.
The study identified multiple antibiotic resistance genes in Aeromonas spp. isolated from freshwater fish in Malaysia, including blaTEM, blaSHV, sul1, aadA, strA-strB, tetA, and tetE, which confer resistance to ampicillin, sulfamethoxazole, streptomycin, and tetracycline.
Antimicrobial Resistance and Comparative Genome Analysis of Klebsiella pneumoniae Strains Isolated in Egypt.
The study identifies multiple antimicrobial resistance genes in the multidrug-resistant K. pneumoniae strain KPE16, including bla NDM-1, bla CTX-M-15, and various aminoglycoside, sulfonamide, and tetracycline resistance genes. Additionally, chromosomal mutations in ompK36, ompK37, and acrR contribute to resistance.
Insight Into Whole Genome of Aeromonas veronii Isolated From Freshwater Fish by Resistome Analysis Reveal Extensively Antibiotic Resistant Traits.
The study identified 17 AMR genes in Aeromonas veronii isolates from tilapia, highlighting extensive antibiotic resistance traits, including resistance to beta-lactams, aminoglycosides, tetracyclines, and others.
Biological Mitigation of Antibiotic Resistance Gene Dissemination by Antioxidant-Producing Microorganisms in Activated Sludge Systems.
The study demonstrates that antioxidant-producing microorganisms, such as Deinococcus radiodurans R1 and Rhodotorula sp., can mitigate the dissemination of antibiotic resistance genes (ARGs) in activated sludge systems by reducing the persistence of plasmid RP4 and the enrichment of sul1 and intl1. These microorganisms also decrease the diversity of ARG hosts and limit the conjugative transfer of ARGs.
Antibiotic resistance genes in layer farms and their correlation with environmental samples.
The study identified and quantified 13 antibiotic resistance genes (ARGs) in layer manure, layer manure fertilizer, and soil samples from Guangdong Province, highlighting the high prevalence and abundance of these genes, particularly ermB, tetA, and sul2, and their potential environmental impact.
Multidrug Resistance Dynamics in Salmonella in Food Animals in the United States: An Analysis of Genomes from Public Databases.
The study analyzed 22,102 Salmonella genomes from public databases to track antimicrobial resistance (AMR) trends in food animals in the United States. It found that the prevalence of multidrug resistance (MDR) decreased in bovines and swine but increased in poultry. Key AMR genes identified include bla CMY-2, bla CTX-M-65, floR, tetA, sul2, aadA2, aac(3)-VIa, qnrB19, qnrB2, bla SHV-12, bla TEM-1, bla CARB-2, aph(3")-Ib, aph(6)-Id, aph(3')-Ia, ant(3")-Ia, aph(4)-Ia, and aac(3)-IVa. A significant mutation, gyrA D87Y, was associated with quinolone resistance in poultry.
Bacterial loads and antibiotic resistance profile of bacteria isolated from the most popular street food (Phuchka) in Bangladesh.
The study identified the presence of tetracycline-resistant Escherichia coli and Staphylococcus spp. in Phuchka and associated food samples, with the resistance confirmed through PCR amplification of the tetA gene.
Monitoring the Microevolution of Salmonella enterica in Healthy Dairy Cattle Populations at the Individual Farm Level Using Whole-Genome Sequencing.
The study identified several AMR genes, including bla CMY-2, floR, sul2, and tetA, in Salmonella enterica isolates from dairy cattle. These genes confer resistance to various antibiotics such as cephalosporins, florfenicol, sulfamethoxazole-trimethoprim, and tetracycline.
Virulence determinants and antimicrobial resistance of E. coli isolated from bovine clinical mastitis in some selected dairy farms of Bangladesh.
The study identified tetracycline resistance gene tetA in 100% of tetracycline-resistant E. coli isolates and blaTEM-1 in 38.9% of E. coli isolates, highlighting the presence of multidrug-resistant E. coli in bovine clinical mastitis.
Antimicrobial susceptibility, multilocus sequence typing, and virulence of listeria isolated from a slaughterhouse in Jiangsu, China.
The study identified tetracycline resistance genes tetA and tetM, erythromycin resistance genes ermA, ermB, and ermC, and the aminoglycoside resistance gene aac(6')-Ib in Listeria isolates from a slaughterhouse in Jiangsu, China.
Antimicrobial Susceptibility and Detection of Virulence-Associated Genes in Escherichia coli Strains Isolated from Commercial Broilers.
The study identified several AMR genes in E. coli strains from commercial broilers, including bla CTX-M-1 and bla CTX-M-2 for cephalosporin resistance, qnrA, qnrB, qnrS for fluoroquinolone resistance, aac(6')-Ib-cr for fluoroquinolone and aminoglycoside resistance, tetA and tetB for tetracycline resistance, sul1 and sul2 for sulfonamide resistance, aadA for aminoglycoside resistance, dfrA and dfrB for trimethoprim resistance, and mcr1 and mcr2 for polymyxin resistance.
Impact of Antibiotic Therapies on Resistance Genes Dynamic and Composition of the Animal Gut Microbiota.
The study examined the impact of antibiotic therapies on the dynamics and composition of resistance genes in the animal gut microbiota, identifying several AMR genes such as blaTEM, tetA, strA, strB, intI1, tetM, mel, floR, mcr-2, oqx B, tetC, tetG, tetO, tetW, tetX, ermB, ermF, sul1, sul2, and others, which were experimentally validated in Escherichia coli.
Phage Cocktail Development against Aeromonas salmonicida subsp. salmonicida Strains Is Compromised by a Prophage.
The study identifies antibiotic resistance genes such as sul1, sul2, floR, tetA, and cat in Aeromonas salmonicida subsp. salmonicida strains, highlighting their role in resistance to sulfonamides, chloramphenicol, and tetracycline. It also shows that the presence of Prophage 3 reduces the effectiveness of phage cocktails against these strains.
First report from Bangladesh on genetic diversity of multidrug-resistant Pasteurella multocida type B:2 in fowl cholera.
The study identified multidrug-resistant Pasteurella multocida type B:2 strains in fowl cholera cases in Bangladesh, highlighting the presence of various virulence factors and antimicrobial resistance genes.
Comparison of antimicrobial resistance and molecular characterization of Escherichia coli isolates from layer breeder farms in Korea.
The study identified several AMR genes in E. coli isolates from layer breeder farms in Korea, including bla TEM-1, tetA, tetB, qnrB, qnrS, sul1, sul2, aac(3)-II, and aac(6')-Ib. These genes conferred resistance to various antibiotics such as beta-lactams, tetracyclines, quinolones, sulfonamides, and aminoglycosides.
Prevalence of genotypic antimicrobial resistance in clinical Shiga toxin-producing Escherichia coli in Norway, 2018 to 2020.
The study identified a low prevalence of genotypic antimicrobial resistance in clinical STEC in Norway, with aminoglycoside resistance being the most common. Key resistance genes included strA, strB, aadA1, sul1, sul2, tetA, blaTEM-1B, and dfrA1.
Genomic comparisons of Escherichia coli ST131 from Australia.
The study identifies multiple AMR genes and mutations in Australian E. coli ST131 isolates, including bla CTX-M-15 and bla CTX-M-27 for beta-lactam resistance, aadA5, strA, strB, mphA, dfrA17, sul1, qacEΔ1, and chrA for resistance to aminoglycosides, macrolides, trimethoprim, sulfonamides, quaternary ammonium compounds, and chromate. Fluoroquinolone resistance mutations in gyrA and parC were also found.
Prevalence and Antimicrobial Resistance Profiles of Foodborne Pathogens Isolated from Dairy Cattle and Poultry Manure Amended Farms in Northeastern Ohio, the United States.
The study identified several antimicrobial resistance genes in foodborne pathogens isolated from dairy cattle and poultry manure amended farms in Northeastern Ohio, including mphA, aadA, aphA1, tetA, aac(3)-IV, sulII, blaTEM, tetB, strA, aac(3)-Iva, ampC, lde, ermB, tet(O), aadB, penA, blaOXA-61, aadE, and aph-3-1.
Antimicrobial Resistance of Salmonella enteritidis and Salmonella typhimurium Isolated from Laying Hens, Table Eggs, and Humans with Respect to Antimicrobial Activity of Biosynthesized Silver Nanoparticles.
The study identified several AMR genes, including blaTEM, tetA, tetB, nfsA, and nfsB, in multidrug-resistant Salmonella enteritidis and Salmonella typhimurium isolates. These genes conferred resistance to ampicillin, tetracycline, and nitrofurantoin. Additionally, biosynthesized silver nanoparticles showed promising antimicrobial activity against these resistant strains.
Recurring outbreaks by the same Escherichia coli ST10 clone in a broiler unit during 18 months.
The study identifies multiple antimicrobial resistance genes, including blaTEM-1B, tetA, dfrA1/sul2, and floR, in E. coli ST10 isolates causing recurrent outbreaks in a broiler unit over 18 months.
Genotypic and Phenotypic Characterization of Novel Sequence Types of Carbapenem-Resistant Acinetobacter baumannii, With Heterogeneous Resistance Determinants and Targeted Variations in Efflux Operons.
The study identifies various AMR genes and mutations in carbapenem-resistant Acinetobacter baumannii strains, including beta-lactamases, aminoglycoside modifying enzymes, and efflux pumps, contributing to multidrug resistance.
Prevalence, Risk Factors, Antimicrobial Resistance and Molecular Characterization of Salmonella in Northeast Tunisia Broiler Flocks.
The study identified the bla CTX-M gene in extended-spectrum beta-lactamase (ESBL)-producing Salmonella strains, along with tetA, tetB, and dfrA1 genes in tetracycline and trimethoprim-resistant strains. High levels of multidrug resistance were observed.
High-resolution genomic surveillance elucidates a multilayered hierarchical transfer of resistance between WWTP- and human/animal-associated bacteria.
The study identifies multiple plasmid-borne AMR genes, including blaTEM-1, aph(3')-I, floR, and tetA, which confer resistance to ampicillin, kanamycin, chloramphenicol, and tetracycline, respectively. These genes are primarily located on conjugative plasmids and show potential for horizontal transfer between WWTP- and human/animal-associated bacteria.
Genomic features of a multidrug-resistant and mercury-tolerant environmental Escherichia coli recovered after a mining dam disaster in South America.
The study identifies a multidrug-resistant Escherichia coli strain (B2C) carrying the bla CTX-M-2 ESBL gene, qacE∆1 efflux pump, and the mer operon, indicating resistance to antibiotics, heavy metals, and disinfectants.
The frequency of tetracycline resistance genes in Escherichia coli strains isolated from healthy and diarrheic pet birds.
The study identified tetA and tetB genes in E. coli isolates from pet birds, which are associated with tetracycline resistance through efflux pump mechanisms.
Virulence and antimicrobial resistance profile of non-typhoidal Salmonella enterica serovars recovered from poultry processing environments at wet markets in Dhaka, Bangladesh.
The study identified several AMR genes in non-typhoidal Salmonella enterica serovars from poultry processing environments in Bangladesh, including bla TEM, tet A, sul 1, and str A/B, which conferred resistance to various antibiotics such as ampicillin, tetracycline, sulfamethoxazole-trimethoprim, and streptomycin.
Decreasing the abundance of tetracycline-resistant Escherichia coli in pig feces during nursery using flavophospholipol as a pig feed additive.
Flavophospholipol (FPL) effectively reduced the abundance of tetracycline-resistant Escherichia coli in pig feces by inhibiting conjugational transfer and growth of resistant plasmids carrying tetA, tetB, blaTEM-1B, mdfA, aph(3')-I, sul2, aadA1, and dfrA1.
Advanced Oxidation Processes for Inactivation of Antibiotic Resistance Genes in Wastewater
The paper discusses the fate of antibiotic resistance genes (ARGs) during wastewater treatment processes, highlighting the inefficiency of conventional methods in removing ARGs and the potential of UV and chlorine-based advanced oxidation processes (AOPs) for inactivating ARGs. It emphasizes the need for improved wastewater treatment strategies to mitigate the spread of antibiotic resistance.
A Genomic and Bioinformatics View of the Classification and Evolution of Morganella Species and Their Chromosomal Accessory Genetic Elements Harboring Antimicrobial Resistance Genes.
The study identified 88 acquired antimicrobial resistance genes (ARGs) in 166 Morganella isolates, with a focus on tetracycline, aminoglycoside, sulfonamide, trimethoprim, and beta-lactam resistance genes. Key ARGs included blaKPC-2, blaNDM-1, aacA4, aadA5, dfrA17, catB3, arr-3, blaOXA-1, aacA4cr, mph(A), rmtB, sul2, floR, qnrS1, tetA, and ermB.
Prevalence, Antimicrobial Resistance, and Whole Genome Sequencing Analysis of Shiga Toxin-Producing Escherichia coli (STEC) and Enteropathogenic Escherichia coli (EPEC) from Imported Foods in China during 2015-2021.
The study identified several antimicrobial resistance genes in STEC and EPEC isolates from imported foods in China, including blaTEM-1B, tetA, tetB, catA1, cmlA1, aadA1, aph(4)-Ia, aac(3)-IV, aph(6)-Id, aph(3")-Ib, sul3, dfrA12, and qnrS1, which conferred resistance to various antibiotics such as ampicillin, tetracycline, chloramphenicol, gentamicin, trimethoprim-sulfamethoxazole, and ciprofloxacin.
Genomic Analysis of ESBL-Producing E. coli in Wildlife from North-Eastern Germany.
The study identified ESBL-producing E. coli in wild boar and wild ruminants with a low prevalence. The most prevalent ESBL type was CTX-M-1. The study also found resistance genes for aminoglycosides, phenicol, sulfonamides, and tetracyclines.
Similarities in Virulence and Extended Spectrum Beta-Lactamase Gene Profiles among Cefotaxime-Resistant Escherichia coli Wastewater and Clinical Isolates.
The study identifies several beta-lactamase genes, including blaCTX-M-1, blaKPC-2, blaTEM-350, blaOXA-1, and blaCTX-M-15, as well as various aminoglycoside, macrolide, and tetracycline resistance genes in cefotaxime-resistant E. coli isolates from hospital and urban wastewater. Mutations in parC, parE, and gyrA contribute to fluoroquinolone resistance.
Copper and Antimicrobial Resistance in Pseudomonas aeruginosa: Mechanisms, Implications, and Clinical Relevance
The study identifies several genes involved in copper homeostasis and resistance in Pseudomonas aeruginosa, including copA1, copA2, cusABC, pcoAB, copZ1, copZ2, ptrA, and the gi-7 genomic island. These genes contribute to copper tolerance and resistance, highlighting their role in the bacterium's adaptation to hospital environments.
Overcoming Multidrug Resistance in Salmonella spp. Isolates Obtained From the Swine Food Chain by Using Essential Oils: An in vitro Study.
The study identified several AMR genes in Salmonella isolates from the swine food chain, including parC, catA1, nfsB, nfsA, blaTEM, tetA, and tetB, which confer resistance to various antibiotics such as gentamicin, amikacin, tobramycin, chloramphenicol, ampicillin, piperacillin, and tetracycline.
Reduced Chlorhexidine Susceptibility Is Associated with Tetracycline Resistance tet Genes in Clinical Isolates of Escherichia coli.
The study identified that the class B tetA gene is associated with reduced susceptibility to chlorhexidine in clinical isolates of Escherichia coli, and this gene is involved in tetracycline resistance as well.
First identification of bla (NDM-5) producing Escherichia coli from neonates and a HIV infected adult in Tanzania.
The study identifies bla NDM-5 producing Escherichia coli in Tanzania, highlighting the presence of carbapenem resistance and other resistance genes on various plasmids.
Co-selective Pressure of Cadmium and Doxycycline on the Antibiotic and Heavy Metal Resistance Genes in Ditch Wetlands.
The study identified several tetracycline resistance genes (tetA, tetG), a cadmium resistance gene (czcA), and a mobile genetic element (intI1) that were significantly enriched under co-exposure to cadmium and doxycycline in ditch wetlands.
Genomic characterization of multidrug-resistant Salmonella serovar Kentucky ST198 isolated in poultry flocks in Spain (2011-2017).
The study identified multiple antimicrobial resistance genes in multidrug-resistant Salmonella serovar Kentucky ST198 isolates from Spain, including genes conferring resistance to aminoglycosides, beta-lactams, sulfonamides, tetracyclines, trimethoprim, and colistin.
Antimicrobial Resistance and Virulence of Non-Typhoidal Salmonella from Retail Foods Marketed in Bangkok, Thailand.
The study identified several AMR genes in Salmonella Enteritidis isolates from retail food samples in Bangkok, including blaTEM-1, tetA, sul2, and dfrA7, which confer resistance to various antibiotics.
Pan-genome and resistome analysis of extended-spectrum ß-lactamase-producing Escherichia coli: A multi-setting epidemiological surveillance study from Malaysia.
The study identified multiple bla CTX-M variants including bla CTX-M-27, bla CTX-M-65, and bla CTX-M-15, along with mcr-1 and mcr-3 genes conferring colistin resistance, and tetA and qnrS genes contributing to tetracycline and fluoroquinolone resistance in ESBL-producing E. coli isolates from both community and clinical settings in Malaysia.
Frequently used therapeutic antimicrobials and their resistance patterns on Staphylococcus aureus and Escherichia coli in mastitis affected lactating cows.
The study identified several antimicrobial resistance genes in Staphylococcus aureus and Escherichia coli isolated from mastitis-affected cows, including mecA, tetK, tetL, tetA, tetB, sul1, and sul2. These genes confer resistance to various antibiotics such as tetracycline, sulfamethoxazole-trimethoprim, and methicillin.
Virulence determinant and antimicrobial resistance traits of Emerging MDR Shiga toxigenic E. coli in diarrheic dogs.
The study identified several AMR genes in MDR Shiga toxigenic E. coli (STEC) isolated from diarrheic dogs in Egypt, including bla TEM, bla CTX-M, bla KPC, bla NDM-1, tet A, tet B, sul 1, and qnr A. These genes confer resistance to various antibiotics such as penicillins, cephalosporins, carbapenems, tetracyclines, sulfonamides, and quinolones.
Gut Commensal Escherichia coli, a High-Risk Reservoir of Transferable Plasmid-Mediated Antimicrobial Resistance Traits.
The study identified multiple plasmid-mediated antimicrobial resistance genes in gut commensal Escherichia coli isolates from healthy individuals, highlighting the potential risk of these bacteria as reservoirs of resistance traits.
Genomics of human and chicken Salmonella isolates in Senegal: Broilers as a source of antimicrobial resistance and potentially invasive nontyphoidal salmonellosis infections.
The study identified multiple antimicrobial resistance genes and mutations in Salmonella isolates from Senegal, highlighting the prevalence of resistance to fluoroquinolones, sulfamethoxazole-trimethoprim, tetracycline, and erythromycin. Key genes included aac(3)-Id, aadA7, blaTEM-1b, blaDHA-1, blaOXA-10, blaCMY-2, dfrA1, dfrA14, floR, fosA, qnrB19, qnrB7, sul2, tetA, tetB, aph(3')-Ib, aph(3")-Ib, and aph(6)-Id. Mutations in parC and gyrA were also associated with fluoroquinolone resistance.
Establishment of Epidemiological Cut-Off Values and the Distribution of Resistance Genes in Aeromonas hydrophila and Aeromonas veronii Isolated from Aquatic Animals.
The study identified several tetracycline resistance genes (tetA, tetB, tetD, tetE), florfenicol resistance gene (floR), chloramphenicol resistance gene (cat), quinolone resistance gene (qnrS), and aminoglycoside resistance genes (aac(6')-1b, strA-strB) in Aeromonas hydrophila and Aeromonas veronii isolates from aquatic animals.
Pathogenic E. coli from Cattle as a Reservoir of Resistance Genes to Various Groups of Antibiotics.
The study identified various AMR genes in pathogenic E. coli strains from cattle in Romania and France, highlighting the presence of multidrug-resistant (MDR) strains and the diversity of resistance mechanisms.
Invited Review: Antimicrobial Use and Antimicrobial Resistance in Pathogens Associated with Diarrhea and Pneumonia in Dairy Calves.
The review identified several AMR genes in pathogens associated with calf diarrhea and pneumonia, including beta-lactamases (blaCMY, blaCTX-M, blaTEM), tetracycline resistance genes (tetA, tetB, tetM, tetO), aminoglycoside resistance genes (strA, strB, aadA), sulfonamide resistance genes (sul1, sul2), phenicol resistance genes (cat, floR), and macrolide/lincosamide resistance genes (cfr, ermB).
Whole Genome Sequence Analysis of Multidrug Resistant Escherichia coli and Klebsiella pneumoniae Strains in Kuwait.
The study identified multiple AMR genes in multidrug-resistant E. coli and K. pneumoniae isolates from Kuwait, including beta-lactamases (blaKPC-2, blaCTX-M-15, blaOXA-1, blaCMY-4, blaTEM), aminoglycoside-modifying enzymes (aac(3)-IIa, aph(6)-Id, aadA5), sulfonamide resistance genes (sul1, sul2), quinolone resistance genes (gyrA_D87N, qnrB1), and others. Colistin resistance was linked to the pmrB_R256G mutation.
Use of genomics to explore AMR persistence in an outdoor pig farm with low antimicrobial usage.
The study identified various AMR genes in E. coli isolates from a low antimicrobial usage pig farm, highlighting the persistence of multidrug-resistant strains despite minimal selective pressure.
IncFIB-4.1 and IncFIB-4.2 Single-Replicon Plasmids: Small Backbones with Large Accessory Regions.
The study characterizes several AMR genes and mutations in IncFIB-4.1 and IncFIB-4.2 plasmids, highlighting their role in conferring resistance to various antibiotics.
Molecular Epidemiology and Antimicrobial Resistance of Clostridioides difficile in Hospitalized Patients From Mexico.
The study identified several AMR genes and mutations in C. difficile isolates from Mexico, including cfrE, ermB, aadE, aadA27, aac(6')-Ie-aph(2'')-Ia, catP, blaCDD2, blaCCD1, tetM, tetO, tetB, tetA, and cdeA, along with mutations in rpoB, rpoC, fusA, and pbp2 associated with resistance to various antibiotics.
Genetic Diversity, Distribution, and Genomic Characterization of Antibiotic Resistance and Virulence of Clinical Pseudomonas aeruginosa Strains in Kenya.
The study identified multiple AMR genes and mutations in P. aeruginosa isolates from Kenya, including carbapenemases (blaNDM-1, blaVIM-6), fluoroquinolone resistance genes (qnrVC1, crpP), aminoglycoside resistance genes (aac(3)-IId, aph(3')-Ib, ant(3'')-Ia), tetracycline resistance genes (tetA, tetG), phenicol resistance genes (floR, cmlA), sulfonamide resistance gene (sul), trimethoprim resistance gene (dfrB), glycopeptide resistance gene (ble), and macrolide resistance gene (EreA). Additionally, mutations in gyrA and parC were associated with fluoroquinolone resistance.
Escherichia marmotae-a Human Pathogen Easily Misidentified as Escherichia coli.
The study identified antimicrobial resistance genes in Escherichia marmotae, including bla KPC, bla CTX-M, bla TEM-1b, and tetA, which confer resistance to carbapenems, beta-lactams, and tetracyclines.
Development of multidrug-resistant Escherichia coli in some Egyptian veterinary farms.
The study identified bla TEM and tetA genes in amoxicillin and oxytetracycline-resistant Escherichia coli isolates from Egyptian veterinary farms, indicating the presence of multidrug-resistant E. coli.
Litter Commensal Bacteria Can Limit the Horizontal Gene Transfer of Antimicrobial Resistance to Salmonella in Chickens.
The study identifies several AMR genes, including blaTEM-1B, tetA, aadA1, mer operon, sul2, silABCFRS, pcoABCDRS, iroBCDEN, and intI1, which are associated with Salmonella enterica serovar Heidelberg isolates from both fresh and reused litter. These genes contribute to resistance against various antibiotics such as ampicillin, tetracycline, gentamicin, sulfonamide, silver, copper, and mercury.
Analysis of Antimicrobial Resistance in Non-typhoidal Salmonella Collected From Pork Retail Outlets and Slaughterhouses in Vietnam Using Whole Genome Sequencing.
The study identified several AMR genes in non-typhoidal Salmonella isolates from pork retail outlets and slaughterhouses in Vietnam, including blaTEM-1, blaTEM-150, blaLAP-2, blaCTX-M-55, dfrA12, dfrA14, floR, cmlA1, tetA, tetB, tetM, mcr-1, mcr-3, qnrS1, mphA, aadA1, aadA2, aac(6')-laa, aac(6')-ly, sul1, sul2, sul3, aph(3")-lb, and aph6-ld. These genes conferred resistance to various antibiotics such as ampicillin, penicillins, first-generation cephalosporins, quinolones, trimethoprim, chloramphenicol, tetracycline, colistin, macrolides, gentamicin, sulfonamides, and others.
Antimicrobial resistance and genetic background of non-typhoidal Salmonella enterica strains isolated from human infections in São Paulo, Brazil (2000-2019).
The study identifies several AMR genes, including blaTEM-1, dfrA1, tetA, sul1, floR, aac(6')-laa, qnrE1, aadA1, and aac(6')-ly, in non-typhoidal Salmonella enterica strains. It also reports mutations in mgrB, pmrB, and pmrC associated with colistin resistance.
Antimicrobial Resistance and Transconjugants Characteristics of sul3 Positive Escherichia coli Isolated from Animals in Nanning, Guangxi Province.
The study identified sul3-positive E. coli strains with multiple antibiotic resistance genes, including sul3, sul2, tetA, floR, oqxA, and mcr-1, highlighting the potential for horizontal gene transfer and the need for long-term monitoring of antimicrobial resistance in Nanning.
Comparison of Two Distinct Subpopulations of Klebsiella pneumoniae ST16 Co-Occurring in a Single Patient.
The study identifies multiple AMR genes and mutations in Klebsiella pneumoniae ST16 isolates, including bla NDM-4, bla OXA-181, and a frameshift mutation in acrR, contributing to carbapenem and fluoroquinolone resistance.
Synthetic ionophores as non-resistant antibiotic adjuvants.
The study identifies the tetA gene as a tetracycline efflux pump in E. coli and K. pneumoniae, demonstrating its role in mediating tetracycline resistance.
Analysis of Salmonella enterica Isolated from a Mixed-Use Watershed in Georgia, USA: Antimicrobial Resistance, Serotype Diversity, and Genetic Relatedness to Human Isolates.
The study identified multiple antimicrobial resistance genes in Salmonella enterica isolates from a mixed-use watershed in Georgia, USA, including bla CMY-2, aadA2, strA, strB, sul1, sul2, tetA, tetC, floR, and dfrA12, which conferred resistance to various antibiotics such as ceftiofur, ceftriaxone, streptomycin, sulfisoxazole, tetracycline, chloramphenicol, and trimethoprim.
Characterisation of Salmonella Enteritidis ST11 and ST1925 Associated with Human Intestinal and Extra-Intestinal Infections in Singapore.
The study identified several AMR genes and mutations in Salmonella Enteritidis isolates, including TEM1D_bla, tetA, and mcr1, along with mutations in gyrA associated with fluoroquinolone resistance.
Nutrient Gradients Mediate Complex Colony-Level Antibiotic Responses in Structured Microbial Populations.
The study characterizes the tetracycline resistance mechanism involving the tet operon in E. coli, highlighting the role of TetA efflux pump and TetR repressor in regulating resistance. It reveals how transient growth in the colony interior enhances resistance gene expression, contributing to population-level resistance.
Nutrient Gradients Mediate Complex Colony-Level Antibiotic Responses in Structured Microbial Populations.
The study characterizes the tetracycline resistance mechanism involving the tet operon in E. coli, highlighting the role of TetA efflux pump and TetR repressor in regulating resistance. It reveals how transient growth in the colony interior enhances resistance gene expression, contributing to population-level resistance.
Prevalence, Characteristics, and Clonal Distribution of Escherichia coli Carrying Mobilized Colistin Resistance Gene mcr-1.1 in Swine Farms and Their Differences According to Swine Production Stages.
The study identified the mobilized colistin resistance gene mcr-1.1 in Escherichia coli isolates from swine farms, highlighting its prevalence and association with multidrug resistance.
Genomic epidemiology and temperature dependency of hypermucoviscous Klebsiella pneumoniae in Japan.
The study identifies multiple AMR genes and mutations in hypermucoviscous Klebsiella pneumoniae isolates from Japan, highlighting the presence of ESBLs, carbapenemases, and other resistance determinants. It also reveals temperature-dependent variations in the HMV phenotype and the genetic diversity of the isolates.
Antibiotic Resistance in Non-Typhoidal Salmonella enterica Strains Isolated from Chicken Meat in Indonesia.
The study identified several AMR genes, including blaTEM, aadA, tetA, and tetB, in NTS strains from chicken meat in Indonesia. Additionally, mutations in gyrA were linked to resistance to nalidixic acid and ciprofloxacin.
Clinical and Genomic Investigation of an International Ceftriaxone- and Azithromycin-Resistant Shigella sonnei Cluster among Men Who Have Sex with Men, Montréal, Canada 2017-2019.
RETRACTED: Isolation and molecular characterization of extended spectrum beta lactamase producing Escherichia coli from chicken meat in Pakistan.
The study identified several AMR genes including blaOXA-1, blaTEM-1, blaCTX-M15, QnrS, TetA, AAC, AAD, Sul1, and Sul2 in E. coli isolates from chicken meat in Pakistan. Mutations in blaOXA-1 (H81Q), blaTEM-1 (C108Y, T214A, K284E, P301S), QnrS (H95R), and Sul2 (E66A) were also detected.
Escherichia coli ST1193: Following in the Footsteps of E. coli ST131
The paper characterizes Escherichia coli ST1193 as an emerging multidrug-resistant clone with various AMR determinants, including beta-lactamases (bla CTX-M-15, bla CTX-M-14, bla CTX-M-27, bla CTX-M-55, bla OXA-1, bla TEM-1, bla CMY-42, bla CMY-2), aminoglycoside-modifying enzymes (aac(3)-IIa, aac(3)-IId, aac(6′)-Ib-cr, aadA1, aadA2, aadA5, aph(3′′)-Ib, aph(6)-Id), and other resistance genes (mcr-1, mph(A), erm(B), dfrA8, dfrA12, dfrA17, sul1, sul2, tetA, tetB).
Molecular Analysis With 16S rRNA PCR/Sanger Sequencing and Molecular Antibiogram Performed on DNA Extracted From Valve Improve Diagnosis and Targeted Therapy of Infective Endocarditis: A Prospective Study.
The study highlights the effectiveness of molecular analysis (MA) combined with molecular antibiogram in improving the diagnosis and targeted therapy of infective endocarditis (IE), particularly in blood culture-negative cases. It shows that molecular antibiogram has high concordance with traditional antimicrobial susceptibility testing (AST) and can identify resistance genes such as aadA1, aacC1, AAC(6)-Ib-cr, QnrS, CTX-M-1 Group, SHV, KPC, and tetA.
Epidemiological investigation on drug resistance of Salmonella isolates from duck breeding farms in Shandong Province and surrounding areas, China.
The study identified 12 types of antibiotic resistance genes in 110 Salmonella isolates from duck farms in Shandong Province, China, including beta-lactam, aminoglycoside, tetracycline, macrolide, and quinolone resistance genes. The most prevalent resistance genes were blaTEM, aac(6')-Ib-cr, and tetA. The study also found that class I integrons and plasmids play a significant role in the dissemination of these resistance genes.
Characterization of metal(loid)s and antibiotic resistance in bacteria of human gut microbiota from chronic kidney disease subjects.
The study identified several antibiotic and metal(loid) resistance genes in gut microbiota from chronic kidney disease (CKD) subjects, including genes encoding beta-lactamases, quinolone resistance proteins, macrolide phosphotransferases, and efflux pumps. Additionally, genes conferring resistance to arsenicals and heavy metals were detected.
Genomic Analysis of a Highly Virulent NDM-1-Producing Escherichia coli ST162 Infecting a Pygmy Sperm Whale (Kogia breviceps) in South America.
The study identifies a multidrug-resistant NDM-1-producing E. coli ST162 strain isolated from a pygmy sperm whale, highlighting the presence of various AMR genes including blaNDM-1, blaTEM-1C, blaOXA-1, and others, as well as mutations in gyrA and parC contributing to fluoroquinolone resistance.
Occurrence of antibiotics and bacterial resistance genes in wastewater: resistance mechanisms and antimicrobial resistance control approaches.
The study identifies several AMR genes and mutations associated with resistance to various antibiotics in wastewater environments, highlighting the role of these genes in the spread of antimicrobial resistance.
Assessment of multidrug-resistant Listeria monocytogenes in milk and milk product and One Health perspective.
The study identified multiple antimicrobial resistance genes in Listeria monocytogenes isolates from milk and milk products, including beta-lactamase genes (bla TEM, bla SHV, bla Z), tetracycline resistance genes (tet A, tet D, tet G, tet K, tet M), sulfonamide resistance genes (sul 1, sul 2), and an aminoglycoside resistance gene (aph (3)-IIa (aphA2)).
Calves as Main Reservoir of Antibiotic Resistance Genes in Dairy Farms.
The study identifies calves as the main reservoir of antibiotic resistance genes (ARGs) in dairy farms, highlighting the presence of bla TEM, erm B, sul 2, and tet A, which confer resistance to penicillins, MLS, sulfonamides, and tetracyclines, respectively.
Biogeographical variation in antimicrobial resistance in rivers is influenced by agriculture and is spread through bacteriophages.
The study identifies the prevalence of tetracycline resistance genes (tetA and tetM) in both bacterial and phage populations in river water, highlighting the role of agricultural areas in promoting phage-induced resistance.
Distribution of ESBL/AmpC-Escherichia coli on a Dairy Farm.
The study identified ESBL/AmpC-producing E. coli on a dairy farm, with a high prevalence in calves. Key resistance genes included blaCTX-M-1, blaCTX-M-15, floR, strA, strB, catA, aadA, dfrA, tetA, tetR, tetY, mph(A), and TEM-105.
A tale of two plasmids: contributions of plasmid associated phenotypes to epidemiological success among Shigella.
The study identifies that the plasmid pKSR100 confers a broader range of antimicrobial resistance compared to pAPR100, contributing to its greater epidemiological success. pKSR100 carries more AMR genes, including those for macrolides, sulfonamides, trimethoprim, beta-lactams, aminoglycosides, and tetracyclines, while pAPR100 has fewer AMR genes, primarily for macrolides, beta-lactams, and tetracyclines.
Antibiotic resistance genes of public health importance in livestock and humans in an informal urban community in Nepal.
The study identified several antibiotic resistance genes, including bla SHV-1, QnrS, ermC, tetA, tetB, aacC2, and aadA1, in various sources such as humans, animals, and water in an urban informal settlement in Nepal.
Genomic characterization of invasive typhoidal and non-typhoidal Salmonella in southwestern Nigeria.
The study identified multiple antibiotic resistance genes and mutations in invasive Salmonella isolates from Nigeria, highlighting the prevalence of multidrug-resistant S. Typhi 3.1.1 and other serovars carrying resistance determinants such as blaTEM-1, aph(3')-Ib, catA1, dfrA14, sul2, tetA, and qnrB19.
Dynamics of Genotypic and Phenotypic Antibiotic Resistance in a Conventional Wastewater Treatment Plant in 2 Years.
The study identified several AMR genes, including beta-lactamases (bla TEM, bla CTX-M-1, bla OXA-1), aminoglycoside resistance genes (strA, strB), sulfonamide resistance genes (sul1, sul2), and tetracycline resistance gene (tetA), in multidrug-resistant bacteria within a wastewater treatment plant over two years.
Antimicrobial Resistance: Mechanisms, Spread, and Control
The paper discusses the prevalence and mechanisms of antimicrobial resistance, focusing on tetracycline resistance genes such as tetA, tetB, tetC, tetD, tetE, tetI, and tetY in Escherichia coli. These genes are associated with efflux mechanisms that contribute to resistance against tetracycline.
Molecular characterization of multi drug resistant Escherichia coli isolates at a tertiary hospital in Abuja, Nigeria.
The study identified several AMR genes in multi-drug resistant E. coli isolates, including bla CTX-M-15, bla CTX-M-14, bla CTX-M-27, bla CTX-M-65, bla OXA-1, bla OXA-2, bla CMY-2, bla NDM-1, bla NDM-5, aac(3)-IId, aac(3)-IIe, aac(6')-Ib-cr, aad A5, ant(2′′)-Ia, aph(3′′)-Ib, aph(3′′)-VI, aph(6)-Id, ermB, ermD, fosA3, fosA7, mdtM, emrD, sul1, sul2, sul3, tetA, tetB, tetM, dfrA1, dfrA7, dfrA8, dfrA12, dfrA14, dfrA17, dfrA82, dfrB4, qepA, qepA1, qepA2, qepA4, qnrB19, qnrS1, qacE, catA1, catA2, catB3, cmlA1, mphA.
Urban rats as carriers of invasive Salmonella Typhimurium sequence type 313, Kisangani, Democratic Republic of Congo.
The study identified multidrug-resistant Salmonella Typhimurium ST313 in urban rats in Kisangani, Democratic Republic of Congo, highlighting their potential role as reservoirs of invasive Salmonella. The resistant isolates carried genes such as blaTEM-1, strA, strB, ant(3')-Ia, aac(3')-IId, sul1, sul2, dfrA1, tetB, and catA10, conferring resistance to multiple antibiotics.
Hitherto-Unnoticed Self-Transmissible Plasmids Widely Distributed among Different Environments in Japan.
The study identified new subgroups of IncP/P-1 and PromA plasmids, including antibiotic resistance genes such as blaIMP-1, blaKPC-2, mcr-1, and various tetracycline and aminoglycoside resistance genes.
Resistance Phenotype and Molecular Epidemiology of Carbapenem-Resistant Klebsiella pneumoniae Isolated from Nanjing Children's Hospital in Jiangsu Province, China.
The study identified several carbapenemase genes, including blaKPC-2, blaNDM-1, blaNDM-5, blaIMP-8, and blaOXA-181, as well as other resistance genes such as blaCTX-M, blaSHV-2, APH(3)-IB, APH(6)-ID, FosA5, tetC, qnrB1, and tetA, contributing to multidrug resistance in CRKP strains isolated from children in Nanjing, China.
WGS-Based Lineage and Antimicrobial Resistance Pattern of Salmonella Typhimurium Isolated during 2000-2017 in Peru.
The study identifies 63 different AMR genes in 90 S. Typhimurium isolates from Peru, including beta-lactamases (blaTEM-181, blaSHV-12, blaSHV-134, blaCTX-M-15), quinolone resistance genes (qnrB5, qnrB19, qnrE2), tetracycline resistance genes (tetA, tetD, tetR), sulfonamide resistance genes (sul3), dihydrofolate reductase (dfrA1, dfrA12), florfenicol resistance gene (floR), lincomycin resistance gene (linG), aminoglycoside resistance genes (aph(3″)-Ib, aph(6)-Id, aadA2), colistin resistance gene (mcr-1), and fosfomycin resistance gene (fosA3).
Identification of a Novel IncHI1B Plasmid in MDR Klebsiella pneumoniae 200 from Swine in China.
The study identifies a novel IncHI1B plasmid, pYhe2001, in MDR Klebsiella pneumoniae 200 from swine, along with several resistance genes including blaCTX-M-27, aadA16, dfrA27, arr-6, aac(6')-Ib-cr, sul1, qnrB2, tetA, and floR. These genes contribute to resistance against multiple antibiotics.
Exposure to Veterinary Antibiotics via Food Chain Disrupts Gut Microbiota and Drives Increased Escherichia coli Virulence and Drug Resistance in Young Adults.
The study found that exposure to veterinary antibiotics via the food chain leads to increased drug resistance and virulence in Escherichia coli, with the identification of multiple resistance genes such as cmlA, tetA, ctx-M1, and various multidrug efflux pump genes.
Hospital Acquired Pathogenic Escherichia coli from Clinical and Hospital Water Samples of Quetta Balochistan.
The study identified ESBL blaCTX-M-15, tetracycline resistance gene tetA, and TMP-SMX resistance gene dfrA1 in E. coli isolates from clinical and hospital water samples, highlighting the presence of multidrug-resistant strains.
Prevalence, antibiotic profile, virulence determinants, ESBLs, and non-β-lactam encoding genes of MDR Proteus spp. isolated from infected dogs.
The study identified multiple AMR genes in MDR Proteus spp. isolated from dogs, including bla TEM, bla SHV, bla CTX-M, bla OXA-1, sul1, tetA, aadA1, qnrA, intI1, ure C, zap A, and rsb A. These genes conferred resistance to various antibiotics such as penicillins, cephalosporins, sulfonamides, tetracyclines, quinolones, and aminoglycosides.
Human pandemic K27-ST392 CTX-M-15 extended-spectrum β-lactamase-positive Klebsiella pneumoniae: A one health clone threatening companion animals.
The study identifies a multidrug-resistant K. pneumoniae strain (LCKp01) carrying the bla CTX-M-15 gene and other clinically important AMR genes, highlighting the global spread of this clone in both human and animal populations.
Salmonella Derby from pig production chain over a 10-year period: antimicrobial resistance, biofilm formation, and genetic relatedness.
The study identified resistance genes blaTEM, aadA, tetA, and floR in Salmonella Derby isolates, which conferred resistance to ampicillin, streptomycin/spectinomycin, tetracycline, and florfenicol, respectively.
Multiplexed Target Enrichment Enables Efficient and In-Depth Analysis of Antimicrobial Resistome in Metagenomes.
The study developed a multiplex PCR-based amplicon sequencing method for efficient and in-depth analysis of the antimicrobial resistome in metagenomes, demonstrating improved recovery of low-abundance antibiotic resistance genes (ARGs) compared to traditional metagenomic shotgun sequencing.
Antimicrobial Resistance Pattern, Clustering Mechanisms and Correlation Matrix of Drug-Resistant Escherichia coli in Black Bengal Goats in West Bengal, India.
The study identified several AMR genes in multidrug-resistant E. coli isolates from goats, including bla CTXM-1, bla AmpC, bla SHV, bla TEM, bla CMY-6, bla CITM, bla NDM-5, qnr B, qnr S, aac(6')-Ib-cr, tet A, tet B, sul 1, and the acrAB efflux pump system.
Occurrence and Molecular Characterization of Multidrug-Resistant Vegetable-Borne Listeria monocytogenes Isolates.
The study identified multiple antibiotic resistance genes in vegetable-borne L. monocytogenes isolates, including SulI, tetA, tetM, and blaTEM, indicating a high prevalence of multidrug-resistant strains.
Antibiotic Susceptibility Profiles and Resistance Mechanisms to β-Lactams and Polymyxins of Escherichia coli from Broilers Raised under Intensive and Extensive Production Systems.
The study identifies several β-lactamase genes, including SHV-12, CTX-M group variants, TEM, OXA, and PMAβ, as well as the mcr-1 gene responsible for polymyxin resistance in E. coli isolates from broilers raised in intensive and extensive systems. The prevalence of reduced susceptibility to antibiotics is higher in isolates from the intensive system.
Epidemiological links and antimicrobial resistance of clinical Salmonella enterica ST198 isolates: a nationwide microbial population genomic study in Switzerland.
The study identifies several AMR genes and mutations associated with ciprofloxacin resistance in Salmonella enterica ST198 isolates, including aac(3)-Id, aadA7, bla TEM-1b, sul1, tetA, qnrB1, qnrS1, bla CTX-M-14b, bla VEB-8, and bla OXA-48. Additionally, inactivating mutations in ramR and acrB were found to contribute to high-level ciprofloxacin resistance.
Whole genome sequencing and characteristics of extended-spectrum beta-lactamase producing Escherichia coli isolated from poultry farms in Banaskantha, India.
The study identified multiple extended-spectrum beta-lactamase (ESBL) genes, including bla TEM, bla SHV, bla OXA, and bla CTX-M subtypes, along with plasmid-mediated AMR genes such as qnrS1, tetA, dfrA14, sul2, aph(3")-lb, aph(6)-ld, and Aph(3')-la in ESBL-producing E. coli isolates from poultry farms in India.
Serious Risk of Tigecycline Resistance in Escherichia coli Isolated from Swine Manure.
The study identifies the presence of various tetracycline resistance genes (TRGs) in doxycycline-resistant E. coli (DRE) strains isolated from swine manure, highlighting the significant risk of tigecycline resistance. The tetX and tet(X4) genes were found to be strongly associated with tigecycline resistance.
Incidence of antibiotic resistance genotypes of Vibrio species recovered from selected freshwaters in Southwest Nigeria.
The study identified multiple antibiotic resistance genes in Vibrio species from freshwater samples in Southwest Nigeria, including sulI, sulII, ampC, blaOXA, blaPSE, tetA, tetE, strA, aacC2, and aphA1, highlighting the environmental spread of resistance genes.
Whole-Genome Sequencing-Based Species Classification, Multilocus Sequence Typing, and Antimicrobial Resistance Mechanism Analysis of the Enterobacter cloacae Complex in Southern China.
The study identified 80 antibiotic resistance genes in 172 Enterobacter cloacae complex isolates, with a focus on beta-lactamases, aminoglycosides, and fluoroquinolones. Key genes included blaACT-2, blaACT-3, blaACT-6, blaACT-9, blaACT-12, blaTEM-1D, blaCTX-M-3, blaSHV-12, blaNDM-1, blaNDM-5, blaIMP-1, blaIMP-4, blaIMP-26, blaKPC-2, qnrS2, qnrE1, aac(6')-Ib, aac(6')-IIc, aph(3')-Ib, aph(6)-Id, aadA, sul2, dfrA12, tetA, ereA, floR, catA2, mcr-10, arr-6, and fosA3.
A First Report of Molecular Typing, Virulence Traits, and Phenotypic and Genotypic Resistance Patterns of Newly Emerging XDR and MDR Aeromonas veronii in Mugil seheli.
The study identified XDR and MDR Aeromonas veronii strains in Mugil seheli carrying resistance genes bla TEM, bla CTX-M, bla SHV, tet A, aad A1, and sul 1.
Comparative genomics analysis of the multidrug-resistant Aeromonas hydrophila MX16A providing insights into antibiotic resistance genes.
The study identified multiple antibiotic resistance genes in Aeromonas hydrophila MX16A, including beta-lactamases, aminoglycoside-modifying enzymes, tetracycline efflux pumps, and quinolone resistance determinants, contributing to its multidrug-resistant phenotype.
Antimicrobial resistance and genomic characterization of Salmonella enterica serovar Senftenberg isolates in production animals from the United States.
The study characterized antimicrobial resistance genes and mutations in Salmonella enterica serovar Senftenberg isolates from production animals in the United States, identifying genes such as aac(6')-Iaa, aph(3")-Ib, aph(6)-Id, blaTEM-1B, blaCMY-2, blaSHV-12, floR, catA2, qnrB2, aac(6')-Ib-cr, aadA1, aadA2, sul1, sul2, tetA, and mcr-9.1, along with mutations in gyrA and parC genes contributing to resistance against various antibiotics.
Occurrence of virulence factors and carbapenemase genes in Salmonella enterica serovar Enteritidis isolated from chicken meat and egg samples in Iraq.
The study identified carbapenemase genes blaIMP, blaOXA-48-like, and blaNDM, along with tetracycline resistance genes tetA and tetB, and trimethoprim-sulfamethoxazole resistance genes dfrA1 and sul1 in Salmonella enterica serovar Enteritidis isolates from chicken meat and eggs in Iraq.
Virulence Determinants and Methicillin Resistance in Biofilm-Forming Staphylococcus aureus from Various Food Sources in Bangladesh.
The study identified the methicillin resistance gene mecA, beta-lactam resistance gene blaZ, and tetracycline resistance genes tetA and tetC in biofilm-forming Staphylococcus aureus isolates from food sources in Bangladesh.
Enrichment of antibiotic resistance genes within bacteriophage populations in saliva samples from individuals undergoing oral antibiotic treatments.
The study found that bla CTX-M1 and tetA resistance genes were enriched in bacteriophage populations in saliva samples from individuals undergoing oral antibiotic treatments, highlighting the role of bacteriophages in the spread of antibiotic resistance.
Occurrence of Antibiotic Resistant Bacteria in Flours and Different Plant Powders Used in Cuisine.
The study identified the presence of antibiotic-resistant coliform bacteria and enterococci in flour, plant powders, and dough samples. The blaSHV, tetA, and tetE genes were detected in isolates, indicating resistance to ampicillin and tetracycline. Enterococci were less prevalent compared to coliform bacteria and were found only in non-cereal flours.
Impact of international travel and diarrhea on gut microbiome and resistome dynamics.
The study identifies several antimicrobial resistance genes, including blaTEM-148, sul2, aph6, and tetA, in diarrheagenic Escherichia coli isolates from international travelers, highlighting the increased resistance gene diversity associated with diarrhea.
The pan-genome of the emerging multidrug-resistant pathogen Corynebacterium striatum.
The study identifies 15 antimicrobial resistance genes in Corynebacterium striatum, including genes conferring resistance to aminoglycosides, tetracyclines, chloramphenicol, macrolides, lincosamides, streptogramins, sulfonamides, and cationic antiseptics. These genes are often located in genomic islands and mobile genetic elements, highlighting the role of horizontal gene transfer in the spread of multidrug resistance.
Molecular Epidemiology of Antimicrobial Resistance and Virulence Profiles of Escherichia coli, Salmonella spp., and Vibrio spp. Isolated from Coastal Seawater for Aquaculture.
The study identified several AMR genes, including blaTEM, tetA, qnrS, strA, and floR, in Escherichia coli, Salmonella spp., and Vibrio spp. isolates from coastal seawater in Thailand. These genes conferred resistance to various antibiotics such as ampicillin, tetracycline, fluoroquinolones, streptomycin, and chloramphenicol.
Extended Spectrum β-Lactamase-Producing Escherichia coli from Poultry and Wild Birds (Sparrow) in Djelfa (Algeria), with Frequent Detection of CTX-M-14 in Sparrow.
The study identifies the bla CTX-M-14 gene in Escherichia coli isolates from sparrows, along with bla CTX-M-15 and bla CTX-M-1 in turkey and chicken isolates, highlighting the role of wild birds in the dissemination of antibiotic resistance.
In Vitro Assessment of Antimicrobial Activity of Phytobiotics Composition towards of Avian Pathogenic Escherichia coli (APEC) and Other E. coli Strains Isolated from Broiler Chickens.
The study identifies several AMR genes in E. coli strains, including aadA, strA/strB, aphA1, aphA2, tetA, tetB, sul1, sul2, sul3, dfrA1, dfrA10, dfrA12, floR, and blaSHV, which confer resistance to various antibiotics such as streptomycin, neomycin, tetracycline, sulfonamides, trimethoprim, chloramphenicol, and cephalosporins.
Antimicrobial resistance profile of Escherichia coli isolated from poultry litter.
The study identified various antimicrobial resistance genes in E. coli isolates from poultry litter, including groEL, tetA, aadA, aph(3)IA, silP, pcoD, sull, qacEdelta1, iroN, ompTp, and hlyF, which were associated with resistance to multiple antibiotics such as cephalothin, tetracycline, ampicillin, streptomycin, and sulphonamides.
Hydrothermal pre-treatment followed by anaerobic digestion for the removal of tylosin and antibiotic resistance agents from poultry litter.
The study characterizes the removal of tylosin and antibiotic resistance genes (ARGs) from poultry litter using hydrothermal pre-treatment followed by anaerobic digestion. It identifies the reduction of ermB, intI1, sul1, and tetA genes, indicating effective mitigation of antibiotic resistance.
A Cross-Validated Feature Selection (CVFS) approach for extracting the most parsimonious feature sets and discovering potential antimicrobial resistance (AMR) biomarkers.
The study presents a Cross-Validated Feature Selection (CVFS) approach for identifying the most parsimonious gene sets for predicting antimicrobial resistance (AMR) from bacterial pan-genomes. The CVFS approach was able to extract both known and novel AMR genes, demonstrating its effectiveness in selecting relevant features for AMR prediction.
Phylogenetic analysis and antibiotic resistance of Escherichia coli isolated from wild and domestic animals at an agricultural land interface area of Salaphra wildlife sanctuary, Thailand.
The study identified several AMR genes in E. coli isolates from wild and domestic animals in Thailand, including blaTEM, blaSHV, blaCMY-2, aac(3)-IV, aadA, tetA, tetB, qnrA, sul3, dfrA1, dfrA5, and dfrA7, which conferred resistance to various antibiotics such as ampicillin, gentamicin, tetracycline, ciprofloxacin, and trimethoprim-sulfamethoxazole.
Isolation of multidrug-resistant Escherichia coli and Salmonella spp. from sulfonamide-treated diarrheic calves.
The study identified multidrug-resistant (MDR) Escherichia coli and Salmonella spp. from sulfonamide-treated diarrheic calves, with the presence of tetA and blaTEM genes contributing to resistance against tetracycline and beta-lactam antibiotics, respectively.
Enhance antibiotic resistance and human health risks in aerosols during the COVID-19 pandemic.
The study identified increased abundances of antibiotic resistance genes (ARGs) in aerosols during the COVID-19 pandemic, particularly sulfonamide (sul1, sul2), tetracycline (tetA, tetC), and beta-lactam (ampC) resistance genes. These genes were associated with heightened antibiotic resistance in airborne bacteria, contributing to elevated human health risks.
Prevalence and abundance of antibiotic-resistant genes in culturable bacteria inhabiting a non-polar passu glacier, karakorum mountains range, Pakistan.
The study identified multiple antibiotic-resistant genes (ARGs) in culturable bacteria from a non-polar glacier in Pakistan, highlighting the presence of resistance mechanisms against various antibiotics.
Molecular characterization of Arcobacter butzleri isolates from poultry in rural Ghana.
The study identified several antimicrobial resistance genes in Arcobacter butzleri isolates from poultry in Ghana, including blaOXA-464, tetM, ermB, and others, highlighting the presence of multidrug-resistant strains and the potential for horizontal and vertical transmission of resistance genes.
Aeromonas hydrophila ST251 and Aeromonas dhakensis are major emerging pathogens of striped catfish in Vietnam.
The study identifies antibiotic resistance genes such as sul1, dfrA1, tetA, qnrS2, aac(6')-Ib4, arr-2, blaAQU, blaOXA-726, cphA3, and cepH in Aeromonas dhakensis and Aeromonas hydrophila isolates from striped catfish in Vietnam, highlighting the emergence of multidrug-resistant strains.
oprL Gene Sequencing, Resistance Patterns, Virulence Genes, Quorum Sensing and Antibiotic Resistance Genes of XDR Pseudomonas aeruginosa Isolated from Broiler Chickens.
The study identified XDR P. aeruginosa strains from broiler chickens in Egypt, which harbor multiple antibiotic resistance genes including bla TEM, bla CTX-M, bla OXA-1, aad A1, tet A, and sul 1. These strains showed resistance to multiple antimicrobial classes.
An optogenetic toolkit for light-inducible antibiotic resistance.
The study presents an optogenetic toolkit enabling light-inducible antibiotic resistance in Escherichia coli, utilizing genes such as bla, knt, cat, and tetA, which confer resistance to carbenicillin, kanamycin, chloramphenicol, and tetracycline, respectively.
Molecular and Antimicrobial Susceptibility Characterization of Escherichia coli Isolates from Bovine Slaughterhouse Process.
The study identified several AMR genes including tetA, strB, aadA, tetB, aac(3)IV, and strA in E. coli isolates from bovine slaughterhouse samples, highlighting the prevalence of tetracycline and streptomycin resistance.
Emergence of colistin resistance and characterization of antimicrobial resistance and virulence factors of Aeromonas hydrophila, Salmonella spp., and Vibrio cholerae isolated from hybrid red tilapia cage culture.
The study identified several AMR genes in Aeromonas hydrophila, Salmonella spp., and Vibrio cholerae isolated from hybrid red tilapia. Notably, mcr-3 was found in A. hydrophila, and qnrS, tetA, blaTEM, and floR were prevalent in Salmonella spp. No colistin resistance genes were detected in V. cholerae.
Multidrug-resistant extended spectrum β-lactamase (ESBL)-producing Escherichia coli from farm produce and agricultural environments in Edo State, Nigeria.
The study identified various AMR genes in ESBL-producing E. coli isolates from agricultural farms and open markets in Edo State, Nigeria, including blaTEM, blaCTX-M-1, blaCTX-M-15, tetM, tetA, tetB, sul1, sul2, sul3, ant(4')-Ia, aacC(3)-1, qnrA, qnrB, qnrC, qnrS, cat::pC194, cat::pC221, intI1, and intI2. These genes conferred resistance to multiple antibiotics, indicating the presence of multidrug-resistant E. coli in the studied environments.
Detection of antimicrobial resistance genes in Lactobacillus spp. from poultry probiotic products and their horizontal transfer among Escherichia coli.
The study identified antimicrobial resistance genes (ARGs) in Lactobacillus spp. from poultry probiotic products, including bla TEM, bla CTX-M-1, bla CTX-M-2, qnr S, tet A, and tet B. These genes were horizontally transferred to E. coli during co-culture, highlighting the potential risk of AMR spread in poultry populations.
Multidrug-resistant Aeromonas bacteria prevalence in Nile tilapia broodstock.
The study identified multidrug-resistant Aeromonas hydrophila strains in Nile tilapia broodstock, with resistance genes sul1, tetA, qnrs, and ermB detected in the isolates.
Phenotypic and genotypic survey of antibiotic resistance in Salmonella enterica isolates from dairy farms in Uruguay.
The study identified 21 AMR genes in Salmonella enterica isolates from dairy farms in Uruguay, including genes conferring resistance to aminoglycosides, tetracyclines, sulfonamides, beta-lactams, and quinolones. Two chromosomal mutations, parC_T57S and acrB_R717Q, were also detected, contributing to resistance against quinolones and azithromycin, respectively.
Genomic Characterization of Carbapenem-Resistant Acinetobacter baumannii (CRAB) in Mechanically Ventilated COVID-19 Patients and Impact of Infection Control Measures on Reducing CRAB Circulation during the Second Wave of the SARS-CoV-2 Pandemic in Milan, Italy.
The study identified various AMR genes in CRAB isolates, including blaOXA-23, aph(3''-Ib, aph(6)-Id, abeM, mexT, abeS, tetA, adeABC, adeJKL, OXA-66, ADC-73, OXA-127, and ADC-30, which contribute to resistance against carbapenems, aminoglycosides, fluoroquinolones, macrolides, tetracyclines, and multiple antibiotics.
Evolution of Antibiotic Resistance in Escherichia coli and Klebsiella pneumoniae Clinical Isolates in a Multi-Profile Hospital over 5 Years (2017-2021).
The study identified various beta-lactamase genes including blaCTX-M, blaTEM, blaOXA, blaKPC, blaNDM, and blaVIM, as well as qnr, aac(6')-Ib, aadA, ermB, mefA, tetA, and oqxAB, which contribute to resistance against multiple antibiotics in E. coli and K. pneumoniae isolates from a hospital over five years.
Prevalence and Characterization of Salmonella Isolated from Chickens in Anhui, China.
The study identified several AMR genes in Salmonella isolates from chickens in Anhui, China, including blaTEM, blaCMY-2, aadA, strA, aph(3')-IIa, aac(6')-Ib-cr, qnrB, qnrS, sul1, sul2, tetA, tetB, cat1, and floR. These genes were associated with resistance to various antibiotics such as ampicillin, cephalosporins, streptomycin, gentamicin, amikacin, fluoroquinolones, sulfamethoxazole, tetracycline, chloramphenicol, and florfenicol.
Exploiting a targeted resistome sequencing approach in assessing antimicrobial resistance in retail foods.
The study identifies a wide array of antimicrobial resistance genes in retail food samples, highlighting the significant role of Enterobacteriaceae in carrying these resistance determinants. The targeted resistome sequencing approach effectively detects and characterizes these genes, demonstrating its superiority over traditional shotgun metagenomics.
Detection of antibiotic-resistant canine origin Escherichia coli and the synergistic effect of magnolol in reducing the resistance of multidrug-resistant Escherichia coli.
The study identified multiple antibiotic resistance genes in canine-derived E. coli, including blaTEM-1, aac(6')-Ib-cr, TetA, Sul, blaCTX-M-1, QnrS, and TetM. It also demonstrated that magnolol enhances the susceptibility of multidrug-resistant E. coli to cefquinome.
High frequency of NDM-1 and OXA-48 carbapenemase genes among Klebsiella pneumoniae isolates in central Iran.
The study identified high frequencies of bla TEM, bla CTX-M1, bla SHV, bla CTX-M15, bla CIT, bla CMY-2, bla NDM, bla OXA-48, qnrB, qnrS, qnrA, tetA, tetB, sul1, sul2, int1, and int2 genes in Klebsiella pneumoniae isolates from central Iran, highlighting the prevalence of multidrug-resistant and carbapenem-resistant strains.
Distribution analysis of tetracycline resistance genes in Escherichia coli isolated from floor surface and effluent of pig slaughterhouses in Banten Province, Indonesia.
The study identified the distribution of tetracycline resistance genes (tetA, tetB, tetC, tetE, tetM, tetO, and tetX) in Escherichia coli isolates from pig slaughterhouses in Banten Province, Indonesia. The tetO gene was the most dominant in floor surface samples, while tetA was dominant in effluent samples.
Prevalence and resistance to antibacterial agents in Salmonella enterica strains isolated from poultry products in Northern Kazakhstan.
The study identified several AMR genes in Salmonella enterica strains from poultry products in Northern Kazakhstan, including tetA, tetB, blaTEM, aadA, sul3, catII, and cmlA, which confer resistance to various antibiotics such as tetracycline, beta-lactams, aminoglycosides, sulfonamides, and chloramphenicol.
Potential Use of a Combined Bacteriophage-Probiotic Sanitation System to Control Microbial Contamination and AMR in Healthcare Settings: A Pre-Post Intervention Study.
The study evaluated the effectiveness of a combined probiotic-phage sanitation system (PCHSφ) in reducing microbial contamination and antimicrobial resistance (AMR) in hospital environments. PCHSφ significantly reduced staphylococcal contamination and AMR gene prevalence compared to conventional chemical disinfection and PCHS alone.
Antimicrobial resistance and genomic characterization of Salmonella enterica isolates from chicken meat.
The study identified multiple antimicrobial resistance genes in Salmonella enterica isolates from chicken meat, including aminoglycoside, beta-lactam, quinolone, tetracycline, sulfonamide, and phenicol resistance genes. These genes were detected using whole genome sequencing and correlated with phenotypic resistance profiles.
Genomic and functional characterization of carbapenem-resistant Klebsiella pneumoniae from hospital wastewater.
The study identified the bla KPC-2 gene as a major contributor to carbapenem resistance in Klebsiella pneumoniae isolates from hospital wastewater, demonstrating its successful in vitro transfer through conjugation.
Antibiotic Resistance among Gastrointestinal Bacteria in Broilers: A Review Focused on Enterococcus spp. and Escherichia coli.
The paper reviews the antibiotic resistance profiles of Enterococcus spp. and Escherichia coli in broilers, highlighting the presence of various resistance genes such as pbp5, aac(6')-Ib, cat pIP501, ermB, tetL, vanA, vanC, blaTEM, blaSHV, blaOXA, blaCMY, blaCTX-M, qnrA, qnrS, sul1, sul2, dfrA1, dfrA12, dfrA14, and dfrA17.
Phenotypic and Genotypic Characteristics of Antimicrobial Resistance in Citrobacter freundii Isolated from Domestic Ducks (Anas platyrhynchos domesticus) in Bangladesh.
The study identified multiple AMR genes in Citrobacter freundii isolates from domestic ducks in Bangladesh, including beta-lactamases (bla TEM-1, bla CMY-2, bla CMY-9, bla CTX-M-14), sulfonamide resistance genes (sul1, sul2), tetracycline resistance genes (tetA, tetB), fluoroquinolone resistance genes (qnrA, qnrB, qnrS), and an aminoglycoside resistance gene (aacC4).
Occurrence of High-Risk Clonal Lineages ST58, ST69, ST224, and ST410 among Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolated from Healthy Free-Range Chickens (Gallus gallus domesticus) in a Rural Region in Tunisia.
The study identified high-risk clonal lineages ST58, ST69, ST224, and ST410 among ESBL-producing E. coli isolates from free-range chickens in Tunisia. Key AMR genes included bla CTX-M-1, bla CTX-M-15, bla CTX-M-55, aac(6')-Ib-cr, qnrS, qnrB, tetB, tetA, sul1, sul2, and mcr-2.
Antimicrobial resistance, Extended-Spectrum β-Lactamase production and virulence genes in Salmonella enterica and Escherichia coli isolates from estuarine environment.
The study identified several AMR genes in Salmonella and E. coli isolates from estuarine environments, including bla TEM, cmlA, sul3, tetA, dfrA12, and bla CTX-M-55, highlighting the presence of multidrug-resistant and ESBL-producing bacteria in these environments.
Antimicrobial resistance and molecular characterization of Klebsiella species causing bovine mastitis in Nghe An province, Vietnam.
The study identified multidrug-resistant Klebsiella spp. isolates from bovine mastitis cases in Vietnam, carrying genes such as acrA Kp, blaSHV, and tetA, which confer resistance to various antibiotics.
A suite of modular, all-synthetic suicide vectors for allelic exchange mutagenesis in multidrug resistant Acinetobacter strains.
The study presents a series of synthetic suicide vectors (pALFI1, pALFI2, pALFI3) for allelic exchange mutagenesis in multidrug-resistant Acinetobacter baumannii strains, utilizing resistance markers such as hygR, tetA, and tpm for effective genetic manipulation.
Molecular epidemiology of enterically colonizing Escherichia coli with resistance against third-generation cephalosporins isolated from stool samples of European soldiers with concomitant diarrhea on deployment in Western African Mali.
The study identified bla CTX-M-15 and bla TEM-1b as the primary genes responsible for third-generation cephalosporin resistance in E. coli isolates from European soldiers in Mali. Additionally, several quinolone resistance genes including qnrS1, gyrA S83L, gyrA D87N, parE S458T, parE S458A, and parC S80I were found. Trimethoprim-sulfamethoxazole resistance was mediated by sul1, sul2, dfrA1, dfrA5, dfrA14, and dfrA17. Gentamicin resistance was associated with aph6-Id, aph3-Ib, aac3-IId, aadA5, and aac6-Ib-cr5. Tetracycline resistance was conferred by tetA, tetB, and tetD.
Antimicrobial resistance and virulence genes of invasive Salmonella enterica from children with bacteremia in north-central Nigeria.
The study identified multiple antimicrobial resistance genes in invasive Salmonella enterica isolates from children with bacteremia in north-central Nigeria, including bla TEM, flo R, qnr A, tet A, tet B, and tet G. These genes conferred resistance to various antibiotics such as ampicillin, trimethoprim-sulfamethoxazole, chloramphenicol, tetracycline, and ciprofloxacin.
Resistance mechanisms of tigecycline in Acinetobacter baumannii.
The study identifies several efflux pumps, outer membrane permeability alterations, and antibiotic target modifications as key mechanisms of tigecycline resistance in Acinetobacter baumannii.
Antimicrobial resistance and molecular characterization of Escherichia coli isolated from bovine mastitis samples in Nghe An province, Vietnam.
The study identified tetracycline resistance genes tetA and tetB, sulfonamide resistance genes sul1 and sul2, and no extended-spectrum beta-lactamase (ESBL) genes in E. coli isolates from bovine mastitis in Vietnam.
Concordance between Genotypic and Phenotypic Drug-Resistant Profiles of Shigella Isolates from Taiyuan City, Shanxi Province, China, 2005 to 2016.
The study identified various AMR genes and mutations in Shigella isolates from Taiyuan City, including beta-lactamases (blaTEM-1, blaOXA-1, blaCTX-M-14, blaCTX-M-55), quinolone resistance genes (qnrS1), aminoglycoside resistance genes (aac(3)-IId), tetracycline resistance genes (tetA, tetB), macrolide resistance genes (mphA, ermB), and chloramphenicol resistance gene (catI). Mutations in gyrA and parC were associated with fluoroquinolone resistance.
Whole-genome sequencing and phylogenetic analysis capture the emergence of a multi-drug resistant Salmonella enterica serovar Infantis clone from diagnostic animal samples in the United States.
The study identifies a multidrug-resistant Salmonella infantis clone harboring a pESI-like megaplasmid with the blaCTX-M-65 gene, which confers resistance to ceftriaxone and ampicillin. Several other AMR genes, including aac(3)-IVa, aadA1, aph(4)-Ia, sul1, tetA, floR, dfrA14, and fosA, were also characterized.
A nosocomial Pseudomonas aeruginosa ST3495 isolated from a wild Burmese python (Python bivittatus) with suppurative pneumonia and bacteremia in Hainan, China.
The study identified Pseudomonas aeruginosa ST3495 isolated from a wild Burmese python with suppurative pneumonia and bacteremia, highlighting its resistance genes catB, blaTEM, ant(3'')-I, and tetA, along with virulence factors.
Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolated from Food-Producing Animals in Tamaulipas, Mexico.
The study identified ESBL-producing E. coli strains in food-producing animals in Tamaulipas, Mexico, with resistance genes including aadA1, blaCTX-M, sul2, and tetA.
Bacterial Communities Associated with Houseflies (Musca domestica L.) Inhabiting Hospices in South Africa.
The study identified antibiotic resistance genes ermB, tetA, blaSHV, and blaTEM in houseflies from hospices in South Africa, indicating potential health risks due to the presence of resistant bacteria.
Characterization of microbial community and antibiotic resistome in intra urban water, Wenzhou China.
The study identified several antimicrobial resistance genes (ARGs) in urban water samples from Wenzhou, China, including intI1, tetA, ermA, ermB, qnrB, sul1, sul2, blaSHV, and blaCTX-M. These genes were found to be associated with different bacterial species and were linked to resistance against various antibiotics such as tetracyclines, erythromycin, fluoroquinolones, sulfonamides, and beta-lactams.
Food risk associated with vegetable consumption, exposure to antimicrobial-resistant strains and pesticide residues.
The study identified several antimicrobial resistance genes in AMR strains isolated from vegetables, including blaTEM, tetA, tetW, tetC, tetD, tetB, qnrS, and sulI. These genes conferred resistance to various antibiotics such as ampicillin, amoxicillin/clavulanic acid, tetracycline, ciprofloxacin, nalidixic acid, and trimethoprim/sulfamethoxazole.
From Farm to Fork: Persistence of Clinically Relevant Multidrug-Resistant and Copper-Tolerant Klebsiella pneumoniae Long after Colistin Withdrawal in Poultry Production.
The study identified silA and pcoD genes associated with copper tolerance in Klebsiella pneumoniae isolates from poultry, and numerous chromosomal mutations linked to colistin resistance.
Single cobalt atoms anchored on Ti(3)C(2)T(x) with dual reaction sites for efficient adsorption-degradation of antibiotic resistance genes.
The study reports a Co-SA/Ti3C2Tx catalyst with dual reaction sites for efficient adsorption and degradation of antibiotic resistance genes, particularly tetA, showing high removal efficiency and potential for practical wastewater treatment applications.
Investigation of multidrug-resistant plasmids from carbapenemase-producing Klebsiella pneumoniae clinical isolates from Pakistan.
The study identified 34 antimicrobial resistance genes (ARGs) in multidrug-resistant (MDR) plasmids from carbapenemase-producing Klebsiella pneumoniae clinical isolates in Pakistan, including bla NDM-1, bla OXA-48, and various beta-lactamases, aminoglycoside resistance genes, and others.
Dominance of Escherichia coli sequence types ST73, ST95, ST127 and ST131 in Australian urine isolates: a genomic analysis of antimicrobial resistance and virulence linked to F plasmids.
The study identified various antimicrobial resistance genes in E. coli isolates from Australian urine samples, including blaCTX-M-15, blaCTX-M-14, blaTEM-28, sul1, sul2, sul3, dfrA17, dfrA5, dfrA1, dfrB4, tetA, tetB, mphA, cmlA1, cmlA5, catB3, sat2, qnrD1, fosA7, aac(3)-IId, aac(3)-IIe, aph(3')-IIa, aph(6)-Id, ant(3'')-IIa, intI1, and intI2. These genes were associated with resistance to various antibiotics such as beta-lactams, sulfonamides, trimethoprim, tetracycline, macrolides, chloramphenicol, streptothricin, quinolones, fosfomycin, and aminoglycosides.
Role of a typical swine liquid manure treatment plant in reducing elements of antibiotic resistance.
The study identified and characterized several antibiotic resistance genes (ARGs) in swine wastewater treatment plants, including blaTEM, ermB, qnrB, sul1, and tetA, which were found to be present in the raw wastewater and showed significant reductions after anaerobic digestion.
Pathogenicity and Antibiotic Resistance Diversity in Clostridium perfringens Isolates from Poultry Affected by Necrotic Enteritis in Canada.
The study identified several antimicrobial resistance genes in Clostridium perfringens isolates from poultry with necrotic enteritis, including tetA, tetB, tet44, InuP, erm(T), and ant(6)-Ib. The erm(T) gene was reported for the first time in C. perfringens and conferred resistance to erythromycin.
Prevalence of Antimicrobial Resistance Among the Hydrogen Sulfide Producing Bacteria Isolated on XLD Agar from the Poultry Fecal Samples.
The study identified the presence of tetracycline resistance gene tetA and beta-lactamase gene blaTEM in hydrogen sulfide-producing bacteria isolated from poultry fecal samples, indicating the prevalence of multidrug-resistant bacteria in poultry environments.
Implications of different waterfowl farming on cephalosporin resistance: Investigating the role of bla(CTX-M-55).
The study identifies bla CTX-M-55 as a prevalent gene encoding a beta-lactamase responsible for cephalosporin resistance in E. coli isolated from waterfowl in different farming environments.
High rate of multidrug resistance and integrons in Escherichia coli isolates from diseased ducks in select regions of China.
The study identified a high rate of multidrug resistance in E. coli isolates from diseased ducks in China, with several AMR genes such as bla TEM, bla CTX-M, qnrS, aadA1, sul1, sul2, tet A, floR, mcr-1, intI1, and intI2 being characterized.
Precision Genome Engineering in Streptococcus suis Based on a Broad-Host-Range Vector and CRISPR-Cas9 Technology.
The study presents a CRISPR-Cas9 system for precise genome editing in Streptococcus suis, enabling the creation of gene deletions and single amino acid substitutions. It also identifies 'CRISPR-escape' mutations in the sly gene that allow resistance to Cas9-mediated DNA cleavage.
The effects of antibiotic use on the dynamics of the microbiome and resistome in pigs.
The study identified several antibiotic resistance genes (ARGs) in porcine fecal microbiota, including aacA-aphD, ermT, lnuB, strB, sul2, tetA, tetM, and blaTEM, which showed increased abundance in antibiotic-treated pigs compared to untreated pigs.
First Report of Aeromonas veronii as an Emerging Bacterial Pathogen of Farmed Nile Tilapia (Oreochromis niloticus) in Brazil.
The study reports the first case of multidrug-resistant Aeromonas veronii causing high mortality in farmed Nile tilapia in Brazil, with resistance to oxytetracycline, enrofloxacin, and amoxicillin, and susceptibility to florfenicol. The resistance mechanisms were confirmed by the presence of qnrS2 and tetA genes.
Genetic Diversity and Antimicrobial Resistance of Extraintestinal E. coli Populations Pre- and Post-Antimicrobial Therapy on Broilers Affected by Colisepticemia.
The study identified several AMR genes and mutations in extraintestinal E. coli populations from broilers treated with enrofloxacin. Key findings include the presence of qnrB19 and qnrS1 genes, which confer fluoroquinolone resistance, and mutations in gyrA, parC, and parE genes associated with fluoroquinolone resistance. Additionally, multiple other AMR genes were detected, indicating multidrug resistance.
Multidrug resistance pattern and molecular epidemiology of pathogens among children with diarrhea in Bangladesh, 2019-2021.
The study identified various AMR genes including blaTEM, qnrB, mcr-1, sxt, and tetA in E. coli, V. cholerae, Salmonella spp., and Shigella spp. These genes conferred resistance to cephalosporins, quinolones, colistin, cotrimoxazole, and tetracycline, highlighting the emergence of multidrug-resistant pathogens among children with diarrhea in Bangladesh.
Regulation Transcriptional of Antibiotic Resistance Genes (ARGs) in Bacteria Isolated from WWTP.
The study identifies several antibiotic resistance genes (ARGs) in bacteria isolated from wastewater treatment plants, including sul, qnr, cat1, aadA1, sat-1, tetA, ermB, and act, which confer resistance to sulfonamides, quinolones, chloramphenicol, streptomycin/spectinomycin, kanamycin, tetracycline, macrolides, and beta-lactams, respectively.
Genomic characterization of colistin-resistant Klebsiella pneumoniae isolated from intensive care unit patients in Egypt.
The study identifies mcr-1.1 as a plasmid-mediated colistin resistance gene and characterizes several chromosomal mutations in mgrB, arnT, pmrA, pmrB, pmrC, phoQ, and arnB that contribute to colistin resistance in K. pneumoniae isolates from Egypt.
Oxytetracycline and heavy metals promote the migration of resistance genes in the intestinal microbiome by plasmid transfer.
The study identifies the tetA gene as a tetracycline resistance gene that is transferred via plasmid RP4 in the intestinal microbiome under the influence of oxytetracycline and heavy metals.
Phenotypic and genotypic antimicrobial resistance correlation and plasmid characterization in Salmonella spp. isolates from Italy reveal high heterogeneity among serovars.
The study identified several antimicrobial resistance genes including blaTEM-1B, sul1, sul2, tetA, tetB, and others in Salmonella isolates from Italy, highlighting the diversity of resistance mechanisms among different serovars.
Antibiotic Resistance Mediated by Escherichia coli in Kuwait Marine Environment as Revealed through Genomic Analysis.
The study identified various antibiotic resistance genes in Escherichia coli isolates from Kuwait's marine environment, including beta-lactamases, aminoglycoside-modifying enzymes, fluoroquinolone resistance genes, sulfonamide resistance genes, tetracycline resistance genes, and macrolide resistance genes. Additionally, the MFS-type drug efflux gene mdfA was commonly found in E. coli isolates.
Isolation and Characterization of the Acadevirus Members BigMira and MidiMira Infecting a Highly Pathogenic Proteus mirabilis Strain.
The study identifies multiple antibiotic resistance genes in the highly pathogenic Proteus mirabilis strain MCS, highlighting its multidrug-resistant profile. Key genes include tetA, aac(6')-Iq, aac(6')-Ib', aadA, dfrA1, blaOXA-9, blaCTX-M-2, vat, catA2, sul1, qacEdeltal, tetQ, blaTEM-135, aadA2, aph(3')-Ia, aph(6)-Id, aph(3'')-lb, and sulI.
Resistance profiles, virulence and antimicrobial resistance genes of XDR S. Enteritidis and S. Typhimurium.
The study identified multiple antimicrobial resistance genes including blaTEM, blaCTX-M, blaNDM, sul1, tetA, aadA1, and ereA in XDR S. Enteritidis and S. Typhimurium isolates from diseased broilers. These genes conferred resistance to various antibiotics such as beta-lactams, sulfonamides, tetracyclines, and aminoglycosides.
Facile synthesis of CuONPs using Citrus limon juice for enhancing antibacterial activity against methicillin-resistant Staphylococcus aureus, beta-lactamase and tetracycline-resistant Escherichia coli.
The study identifies the presence of methicillin-resistant Staphylococcus aureus, beta-lactamase-resistant Escherichia coli, and tetracycline-resistant Escherichia coli using PCR amplification of specific genes (mecA, blaTEM-1, and tetA).
The Resistance and Virulence Characteristics of Salmonella Enteritidis Strain Isolated from Patients with Food Poisoning Based on the Whole-Genome Sequencing and Quantitative Proteomic Analysis.
The study identified multiple antimicrobial resistance genes in the multidrug-resistant Salmonella Enteritidis strain 27A, including beta-lactamase blaTEM-194, aminoglycoside resistance genes aac(6)-Ib, aac(6)-If, aph(3”)-Ib, and aph(6)-Id, tetracycline resistance genes tetA, tetR, and tet34, and efflux pump genes acrA, acrB, tolC, oprM, mexE, mexF, macB, mdtG, mdtH, mdtL, mdtM, mdtK, rosA, emrA, emrR, ykkc, and vanRA.
Extensive Expression of the Virulome Related to Antibiotic Genotyping in Nosocomial Strains of Klebsiella pneumoniae.
The study identified several antibiotic resistance genes in multidrug-resistant Klebsiella pneumoniae strains, including beta-lactamases (bla TEM, bla SHV, bla CITM, bla CTXM-1), tetracycline resistance (tetA), sulfonamide resistance (sul1), aminoglycoside resistance (aac(3)-IV, aadA1), and others.
Colibacillosis in lambs and kids in Egypt: Prevalence, serogroups, antibiogram profile, virulence genes distribution and antimicrobial resistance genes.
The study identified blaSHV, blaCTX-M, and tetA as the primary antimicrobial resistance genes in E. coli isolates from diarrheic lambs and kids in Egypt, contributing to high resistance rates against several antibiotics.
Detection of tetracycline resistance genes and their diversity in Escherichia coli isolated from pig farm waste in Banten province, Indonesia.
The study identified several tetracycline resistance genes, including tetA, tetB, tetC, tetM, tetO, and tetX, in Escherichia coli isolated from pig farm waste in Banten province, Indonesia. tetX and tetO were the most prevalent genes, with high frequencies detected in both solid waste and wastewater samples.
Prevalence of Escherichia coli isolated from oropharynx and trachea of clinically sick poultry and antimicrobial resistance pattern of the strains isolated.
The study identified the presence of tetA, tetB, and tetC genes in tetracycline-resistant E. coli isolates from poultry, highlighting the role of these genes in oxytetracycline resistance.
Comparative Genomic Analysis Reveals the Emergence of ST-231 and ST-395 Klebsiella pneumoniae Strains Associated with the High Transmissibility of bla(KPC) Plasmids.
The study identifies multiple AMR genes, including blaOXA-232, blaCTX-M-15, dfrA14, aac(6')-Ib-cr, and others, in K. pneumoniae isolates, highlighting the role of integrons and plasmids in the dissemination of resistance.
Pyogenic liver abscess caused by extended-spectrum β-lactamase-producing hypervirulent Klebsiella pneumoniae diagnosed by third-generation sequencing: a case report and literature review.
The study identifies the presence of extended-spectrum β-lactamase-producing hypervirulent Klebsiella pneumoniae in a case of pyogenic liver abscess, highlighting the detection of drug resistance genes including CTX-M, tetA, and qnrS using nanopore-based metagenomic third-generation sequencing.
Virulence genotype and phenotype of two clinical isolates of Arcobacter butzleri obtained from patients with different pathologies.
The study identified tetracycline resistance genes tetO and tetA, as well as the beta-lactamase gene bla3, in the clinical isolates of Arcobacter butzleri. These genes conferred resistance to tetracycline, ampicillin, and amoxicillin-clavulanic acid.
Characterization of Salmonella enterica serovar Isangi from South Africa, 2020-2021.
The study identified multiple AMR genes in Salmonella Isangi isolates, including ESBL genes like bla CTX-M-15, bla CTX-M-22, bla CTX-M-3, and others, as well as plasmid-mediated AmpC genes like bla DHA-1 and bla NDM-1. Resistance to multiple antibiotics was observed, highlighting the need for continued monitoring of AMR in this serovar.
Occurrence of Antibiotic-Resistant Bacteria in Fish and Seafood from Slovak Market.
The study identified the tetA resistance gene in tetracycline-resistant Kluyvera cryocrescens isolates from fish and seafood samples.
A One Health approach based on genomics for enhancing the Salmonella enterica surveillance in Colombia.
The study identified various AMR genes in Salmonella enterica serovars, including qnrB81, aph_6, sul2, tetA, blaCMY_2, qnrB19, aac_3_IV, blaLEN_15, aph4_la, aadA1, blaTEM_95, qnrB82, and mcr-5.1, which confer resistance to quinolones, aminoglycosides, sulfonamides, tetracyclines, beta-lactams, and colistin.
Dynamics of antimicrobial resistance and virulence of staphylococcal species isolated from foods traded in the Cape Coast metropolitan and Elmina municipality of Ghana.
The study identified multiple antimicrobial resistance genes in staphylococcal isolates from food samples, including genes conferring resistance to tetracycline, gentamicin, methicillin, erythromycin, and vancomycin. High prevalence of multidrug resistance was observed, highlighting the potential health risks associated with food-borne staphylococci.
The secrets of environmental Pseudomonas aeruginosa in slaughterhouses: Antibiogram profile, virulence, and antibiotic resistance genes.
The study identified multiple antibiotic resistance genes in Pseudomonas aeruginosa isolates from slaughterhouses, including blaCTX-M, blaAmpC, blaSHV, blaNDM, IMP-1, aac(6')-Ib, ant(4')IIb, qnrB, tetA, mexY, TEM, and rmtC. These genes confer resistance to various antibiotics such as beta-lactams, aminoglycosides, fluoroquinolones, and tetracyclines.
Antimicrobial Resistance Profiles of Multidrug-Resistant Enterobacteria Isolated from Feces of Weaned Piglets.
The study identified the presence of various AMR genes, including bla TEM, bla SHV, bla CTX-M, tetA, and mcr-1, in multidrug-resistant enterobacteria isolated from weaned piglets. These genes were associated with resistance to beta-lactams, tetracycline, and colistin.
The fate of antibiotic resistance genes during anaerobic digestion of sewage sludge with ultrasonic pretreatment.
The study investigated the effect of ultrasonic pretreatment on the fate of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) during anaerobic digestion of sewage sludge. It found that ultrasonic pretreatment significantly reduced the relative abundance of ARGs and MGEs, with 60 minutes of pretreatment achieving the highest removal rate of 41.70% for total ARGs.
Serovars, Virulence and Antimicrobial Resistance Genes of Non-Typhoidal Salmonella Strains from Dairy Systems in Mexico.
Characteristics of antimicrobial resistance in Escherichia coli isolated from retail meat products in North Carolina.
The study identified several AMR genes in E. coli isolates from retail meat products in North Carolina, including aac(3)-IV, aadA1, aph(3'')-lb, blaTEM-1, tetB, and others, highlighting the prevalence of multidrug-resistant E. coli in ground turkey.
Metagenomic assembly is the main bottleneck in the identification of mobile genetic elements.
The study evaluated the performance of tools for identifying mobile genetic elements (MGEs) and antimicrobial resistance genes (ARGs) in metagenomic data. It found that metagenomic assembly is the main bottleneck in accurately identifying MGEs and ARGs, with moderate precision and sensitivity for plasmids, phages, IS elements, and ARGs.
Low temperatures do not impair the bacterial plasmid conjugation on poultry meat.
The study demonstrates that non-pathogenic E. coli can acquire an IncB/O-plasmid carrying multiple antimicrobial resistance genes through conjugation on poultry meat, even at low temperatures. This highlights the potential risk of antimicrobial resistance spread through food products.
Antimicrobial resistance, virulence profile, and genetic analysis of ESBL-producing Escherichia coli isolated from Nile tilapia in fresh markets and supermarkets in Thailand.
The study identified the presence of ESBL-producing E. coli in Nile tilapia, with the most prevalent AMR genes being bla TEM, tetA, and qnrS. These genes conferred resistance to ampicillin, tetracycline, and fluoroquinolones, respectively.
Salmonella enterica serovars linked with poultry in India: antibiotic resistance profiles and carriage of virulence genes.
The study identified the tetA gene as a significant contributor to tetracycline resistance in various Salmonella serovars isolated from poultry in India.
Genomic Features of an MDR Escherichia coli ST5506 Harboring an IncHI2/In229/bla(CTX-M-2) Array Isolated from a Migratory Black Skimmer.
An MDR E. coli ST5506 strain was isolated from a migratory black skimmer, harboring a complex array including bla(CTX-M-2), bla(TEM-1C), aac(3)-VIa, aadA1, aph(3′)-Ia, sul1, dfrA27, and tetA, indicating resistance to various antimicrobials.
Rare serovars of non-typhoidal Salmonella enterica isolated from humans, beef cattle and abattoir environments in Nigeria.
Genomic insights into ESBL-producing Escherichia coli isolated from non-human primates in the Peruvian Amazon.
The study identified three bla CTX-M variants (bla CTX-M-15, bla CTX-M-55, and bla CTX-M-65) and a broad resistome in ESBL-producing E. coli strains isolated from non-human primates in the Peruvian Amazon.
Clonal and plasmidic dissemination of critical antimicrobial resistance genes through clinically relevant ExPEC and APEC-like lineages (ST) in the dairy cattle population of Québec, Canada.
The study identifies the dissemination of critical AMR genes, including bla CTX-M-15, qnrS1, and bla TEM-1, in E. coli isolates from dairy cattle in Quebec, highlighting the persistence of these genes through plasmids and clones despite reduced antimicrobial use.
Meat and meat products as potential sources of emerging MDR Bacillus cereus: groEL gene sequencing, toxigenic and antimicrobial resistance.
The study identified multiple antimicrobial resistance genes, including bla1, bla2, ermA, tetA, and tetB, in multidrug-resistant Bacillus cereus isolates from meat and meat products.
Antimicrobial resistance in aeromonads and new therapies targeting quorum sensing.
The paper discusses the prevalence of antimicrobial resistance in Aeromonas species, highlighting the presence of various beta-lactamase genes such as blaTEM-24, blaIMP-19, blaVIM-4, blaKPC-2, blaNDM-1, blaVIM-2, blaOXA-48, blaIMP-13, blaGES-5, blaTEM-1, blaSHV-12, blaVEB-9, blaMOX, blaFOX, blaACC, and others. It also identifies genes like cphA, vat, mcr-3.41, mcr-7.1, sul, dfr, tetA, rsmA, and adeF associated with resistance to sulfonamides, trimethoprim, tetracycline, polymyxin, and other antibiotics. The study emphasizes the role of horizontal gene transfer and mobile genetic elements in the dissemination of these resistance genes.
Phage vB_Ec_ZCEC14 to treat antibiotic-resistant Escherichia coli isolated from urinary tract infections.
The study identifies several antibiotic resistance genes in multidrug-resistant E. coli isolates, including blaTEM, blaSHV, blaCTX, and tetA, which confer resistance to amoxicillin, ceftriaxone, and tetracycline. These findings highlight the genetic basis of resistance in the isolates.
Duplicated antibiotic resistance genes reveal ongoing selection and horizontal gene transfer in bacteria.
The study demonstrates that antibiotic selection drives the evolution of duplicated antibiotic resistance genes (ARGs) through intragenomic transposition, with a significant enrichment of duplicated ARGs in isolates from humans and livestock.
Emergence of multidrug-resistant Bacillus spp. derived from animal feed, food and human diarrhea in South-Eastern Bangladesh.
The study identifies multiple AMR genes in Bacillus spp. isolated from animal feed, food, and human diarrhea in Bangladesh, highlighting the prevalence of multidrug resistance and the need for monitoring in the agricultural and food sectors.
Genomic Features and Phylogenetic Analysis of Antimicrobial-Resistant Salmonella Mbandaka ST413 Strains.
The study identified nine resistance genes, including aac(6')-Iaa, sul1, qacE, blaOXA-129, tet(B), and aadA1, as well as a point mutation in ParC (T57S) associated with quinolone resistance in Salmonella Mbandaka ST413 strains.
Dynamical model of antibiotic responses linking expression of resistance genes to metabolism explains emergence of heterogeneity during drug exposures.
The study presents a mathematical model explaining how the expression of tetracycline resistance genes (tetA and tetR) interacts with cellular metabolism to influence heterogeneity in bacterial responses to antibiotics.
Unveiling distinct genetic features in multidrug-resistant Escherichia coli isolated from mammary tissue and gut of mastitis induced mice.
The study identified multiple antimicrobial resistance genes in multidrug-resistant E. coli strains isolated from mastitis-induced mice, highlighting the complex resistome and potential for horizontal gene transfer.
Isolation, Identification, Antimicrobial Resistance, Genotyping, and Whole-Genome Sequencing Analysis of Salmonella Enteritidis Isolated from a Food-Poisoning Incident.
The study identified multiple antimicrobial resistance genes in Salmonella Enteritidis strain 21A, including aac(6')-Iaa, blaTEM-1, qnrB, floR, tetA, sul1, and sul2, which conferred resistance to various antibiotics such as aminoglycosides, beta-lactams, quinolones, tetracyclines, and sulfonamides.
Occurrence and molecular characteristics of antimicrobial resistance, virulence factors, and extended-spectrum β-lactamase (ESBL) producing Salmonella enterica and Escherichia coli isolated from the retail produce commodities in Bangkok, Thailand.
The study identified several AMR genes and mutations in Salmonella enterica and Escherichia coli isolated from retail produce in Bangkok, Thailand. Key findings include the presence of bla TEM, qnrS, tetA, tetB, strA, and strB genes, as well as gyrA and parC mutations associated with ciprofloxacin resistance.
Phenotypic, molecular detection, and Antibiotic Resistance Profile (MDR and XDR) of Aeromonas hydrophila isolated from Farmed Tilapia zillii and Mugil cephalus.
The study identified several AMR genes in Aeromonas hydrophila isolates from farmed fish, including bla_pse1, bla_SHV, tetA, and sul1, which confer resistance to beta-lactams, tetracyclines, and sulfonamides.
Isolation and molecular characterization of multidrug‑resistant Escherichia coli from chicken meat.
The study identified multidrug-resistant Escherichia coli from chicken meat, highlighting the presence of resistance genes such as blaTEM, tetA, ereA, CITM, and cmlA.
Antimicrobial Resistance and Molecular Characterization of Salmonella Rissen Isolated in China During 2008-2019.
The study identified multiple AMR genes in Salmonella Rissen isolates from China, including blaTEM, sul2, sul3, tetA, strA, strB, aadA, intl1VR(cx), and qacED1, which contribute to resistance against various antibiotics such as ampicillin, trimethoprim-sulfamethoxazole, tetracycline, and streptomycin.
Multilocus sequence typing and antibiotic resistance of Aeromonas isolated from freshwater fish in Hebei Province.
The study identified several AMR genes in Aeromonas isolates from freshwater fish in Hebei Province, including TEM, tetA, floR, sul2, Ant(3")-I, and qacEΔ1, which confer resistance to various antibiotics such as penicillin, tetracycline, chloramphenicol, sulfonamide, aminoglycoside, and quinolone.
Horizontal transfer characterization of ColV plasmids in bla(CTX-M)-bearing avian Escherichia coli.
The study characterizes the horizontal transfer of ColV plasmids in bla(CTX-M)-bearing avian E. coli, identifying multiple resistance genes and virulence factors associated with these plasmids.
Activity of Epsilon-poly-L-lysine against Multidrug-Resistant Pseudomonas aeruginosa and Klebsiella pneumoniae Isolates of Urinary Tract Infections.
The study identified various beta-lactamase genes, including blaSPM, blaKPC, blaSHV, blaCTX-M, blaOXA, blaTEM, blaPER, blaVIM, and blaVIM-2 in Pseudomonas aeruginosa, and blaCTX-M, blaTEM, blaKPC, blaNDM, and blaOXA in Klebsiella pneumoniae. Additionally, aac(3)-IV, aadA1, aac(3)-II, sul2, sul1, sul3, dfrA, cmlA, and tetA were found to confer resistance to aminoglycosides, sulfonamides, trimethoprim, chloramphenicol, and tetracyclines.
Unseen Weapons: Bacterial Extracellular Vesicles and the Spread of Antibiotic Resistance in Aquatic Environments.
The paper discusses the role of bacterial extracellular vesicles (BEVs) in the spread of antibiotic resistance in aquatic environments, highlighting specific genes such as blaCTX-M, tetA, floR, and sul/I that confer resistance to beta-lactam, tetracycline, florfenicol, and sulfonamide antibiotics, respectively.
Molecular characterization of Aeromonas hydrophila detected in Channa marulius and Sperata sarwari sampled from rivers of Punjab in Pakistan.
The study identified several AMR genes in Aeromonas hydrophila isolates from fish samples, including tetA, blaTEM, qnrA, qnrB, sul1, and sul3, indicating multidrug resistance.
Antibiotic susceptibility and resistance genes profiles of Vagococcus salmoninarum in a rainbow trout (Oncorhyncus mykiss, Walbaum) farm.
The study identified several antibiotic resistance genes in Vagococcus salmoninarum isolates from a rainbow trout farm, including tetA, sul1, sul2, sul3, dhfr1, ereB, and floR, which confer resistance to tetracycline, sulfonamides, trimethoprim/sulfamethoxazole, erythromycin, lincomycin, pristinamycin, tylosin, and florfenicol.
Comparison of genotypic and phenotypic antimicrobial resistance profiles of Salmonella enterica isolates from poultry diagnostic specimens.
The study identified 31 AMR genes in 97 Salmonella enterica isolates from poultry, including aac(3)-IId, aac(3)-IVa, aac(3)-VIa, aac(6′)-Ib4, ant(2′′)-Ia, grdA, aph(3′)-Ia, aph(3′)-IIa, aadA1, aadA2, aadA7, aadA13, aph(3′)-Ib, aph(6)-Ic, aph(6)-Id, aph(4)-Ia, blaCMY-2, blaCTX-M-1, blaHER-3, blaTEM-1, floR, tetA, tetB, tetC, dfrA12, sul1, sul2, fosA7, qnrB19, ble, and mcr-9.
Exploring the resistome, virulome, and mobilome of multidrug-resistant Klebsiella pneumoniae isolates: deciphering the molecular basis of carbapenem resistance.
The study identifies multiple antibiotic resistance genes, including bla CTX-M-15, bla TEM, bla SHV, bla NDM, bla OXA, and others, contributing to carbapenem resistance in Klebsiella pneumoniae isolates. Mutations in porin genes ompK35 and ompK36, as well as in gyrA and parC, are associated with reduced susceptibility to carbapenems and fluoroquinolones.
Environmentally Relevant Concentrations of Tetracycline Promote Horizontal Transfer of Antimicrobial Resistance Genes via Plasmid-Mediated Conjugation.
Tetracycline at environmentally relevant concentrations enhances the conjugative transfer of antimicrobial resistance genes via plasmid pVP52-1 from Vibrio parahaemolyticus to Escherichia coli. The study identifies tetA and tetR(A) as key tetracycline resistance genes involved in this process.
Prevalence of multidrug-resistant Escherichia coli isolates and virulence gene expression in poultry farms in Jos, Nigeria.
The study identified multidrug-resistant Escherichia coli isolates in poultry farms in Jos, Nigeria, with resistance genes including tetA, gyrA, sul1, and ampC.
Genomic characterization of multi drug resistant ESBL-producing Escherichia coli isolates from patients and patient environments in a teaching hospital in Ghana.
The study identified multiple AMR genes in ESBL-producing E. coli isolates from patients and the hospital environment, including bla CTX-M-15, bla TEM-1B, bla OXA-1, and various aminoglycoside, macrolide, tetracycline, sulfonamide, and trimethoprim resistance genes. Additionally, PMQR genes like qnrS1, qnrB19, qnrB4, and qepA4 were detected, contributing to quinolone resistance.
Pathogenomics analysis of high-risk clone ST147 multidrug-resistant Klebsiella pneumoniae isolated from a patient in Egypt.
The study identifies multiple AMR genes in the MDR-KP isolate WSF99, including various beta-lactamases, carbapenemase, aminoglycoside modifying enzymes, fluoroquinolone resistance genes, and others, highlighting the complex resistance profile of this high-risk clone.
Multi-drug resistant (MDR) Gram-negative pathogenic bacteria isolated from poultry in the Noakhali region of Bangladesh.
The study identified multiple AMR genes, including blaTEM, blaSHV, tetA, tetB, sul1, sul2, and mcr-1, in various multidrug-resistant Gram-negative bacteria isolated from poultry in Bangladesh. These genes conferred resistance to a wide range of antibiotics, highlighting the significant public health concerns associated with AMR in poultry.
The synergy effect of matrine and berberine hydrochloride on treating colibacillosis caused by an avian highly pathogenic multidrug-resistant Escherichia coli.
The study identified multiple antibiotic resistance genes in a multidrug-resistant Escherichia coli strain, including blaTEM, ermA, ermB, aadA1, qnrS, qepA, oqxA, tetA, tetB, and tetC, which conferred resistance to various antibiotics such as beta-lactams, macrolides, aminoglycosides, quinolones, and tetracyclines. The combination of matrine and berberine hydrochloride showed synergistic antibacterial effects against this strain.
Resolved genomes of wastewater ESBL-producing Escherichia coli and metagenomic analysis of source wastewater samples.
The study identified several beta-lactam resistance genes, including bla CTX-M-55, bla TEM-1, and bla SHV-2A, along with aminoglycoside, tetracycline, and sulfonamide resistance genes in ESBL-producing E. coli isolates from wastewater samples.
Phylogenetics and Mobilization of Genomic Traits of Cephalosporin-Resistant Escherichia coli Originated from Retail Meat.
The study identified multiple AMR genes in cephalosporin-resistant E. coli from retail meat, including bla CTX-M-1, bla SHV-12, bla CMY-2, and others, highlighting the role of mobile genetic elements in the spread of resistance.
Unde venis? Bacterial resistance from environmental reservoirs to lettuce: tracking microbiome and resistome over a growth period.
The study identified multidrug and β-lactam antibiotic resistance genes (ARGs) in lettuce and water, while lettuce and soil uniquely shared mainly glycopeptide and tetracycline ARGs. Manure was found to be the main source of resistance markers on young lettuce plants.
High Carriage of tetA, sul1, sul2 and bla (TEM) Resistance Genes among the Multidrug-resistant Uropathogenic Escherichia coli (UPEC) Strains from Malaysian Patients.
The study identified the high prevalence of tetA, sul1, sul2, and bla TEM resistance genes among multidrug-resistant Uropathogenic Escherichia coli (UPEC) strains in Malaysia.
Biofilm enhanced the mitigations of antibiotics and resistome in sulfadiazine and trimethoprim co-contaminated soils.
The study identifies several AMR genes, including aadA7, aac(6')-II, aac(3)-iid, aadD, tetA, tetM, tetX, and sul2, in Arthrobacter sp. D2, which are involved in resistance to aminoglycosides, tetracyclines, and sulfonamides. These genes were experimentally validated using high-throughput qPCR analysis.
Assessment of the presence of multidrug-resistant Escherichia coli, Salmonella and Staphylococcus in chicken meat, eggs and faeces in Mymensingh division of Bangladesh.
The study identified multiple AMR genes in E. coli, Salmonella spp., and Staphylococcus aureus isolated from chicken meat, eggs, and faeces in Bangladesh, highlighting the presence of multidrug-resistant pathogens.
Genomic analysis of Enterobacteriaceae from colorectal cancer patients at a tertiary hospital in Ghana: a case-control study.
The study identified various antimicrobial resistance genes in Enterobacteriaceae isolated from colorectal cancer patients and healthy controls, including ampC2, ampH, strA, strB, mphA, sul1, sul2, tetA, tetR, and dfrA14.
Genomics unveils country-to-country transmission between animal hospitals of a multidrug-resistant and sequence type 2 Acinetobacter baumannii clone.
The study identifies several AMR genes and mutations in a multidrug-resistant Acinetobacter baumannii clone, including blaCARB-16, tetA, gyrA, parC, IS26, ABGRI1, ABGRI2, aphA1, strA, and strB, which contribute to resistance against various antibiotics.
Surveillance of travel-associated isolates elucidates the diversity of non-pandemic Vibrio cholerae.
The study identified various AMR genes in travel-associated V. cholerae isolates, including catB9, floR, sul2, and tetA, which confer resistance to chloramphenicol, sulfonamide, and tetracycline. These genes were detected in both 7PET and non-7PET lineages.
Determinants of Antibiotic Resistance and Virulence Factors in the Genome of Escherichia coli APEC 36 Strain Isolated from a Broiler Chicken with Generalized Colibacillosis.
The study identifies multiple antibiotic resistance genes in the E. coli APEC 36 strain, including beta-lactamases, aminoglycoside modifying enzymes, fluoroquinolone resistance genes, and efflux pumps, indicating a high level of multidrug resistance.
Guanethidine Restores Tetracycline Sensitivity in Multidrug-Resistant Escherichia coli Carrying tetA Gene.
Guanethidine restores tetracycline sensitivity in multidrug-resistant E. coli carrying the tetA gene by inhibiting the TetA efflux pump, leading to increased intracellular tetracycline concentration and reduced MIC.
Molecular Characterization of Multidrug-Resistant Escherichia coli from Fecal Samples of Wild Animals.
The study identified multiple AMR genes in E. coli isolates from wild animals, including beta-lactamases (bla TEM-1B, bla CTX-M-65, bla CTX-M-55, bla EC-1982), aminoglycoside resistance genes (aac(3)-IIa, aadA2, aadA5, ant(3")-Ia, aph(3")-Ib, aph(3′)-Ia, aph(6)-Id), tetracycline resistance genes (tetB, tetA), trimethoprim resistance genes (dfrA17, dfrA1, dfrA5, dfrA12), sulfonamide resistance genes (sul1, sul2, sul3), macrolide/lincosamide/streptogramin resistance genes (mphB, lnuF, ermC, mefC), quinolone resistance genes (qnrB19, qnrB5, qnrS1, qnrS2), and others. Additionally, point mutations in gyrA, parC, and parE were associated with fluoroquinolone resistance.
Molecular Characterization of Multidrug-Resistant Escherichia coli from Fecal Samples of Wild Animals.
The study identified multiple AMR genes in E. coli isolates from wild animals, including beta-lactamases (bla TEM-1B, bla CTX-M-65, bla CTX-M-55, bla EC-1982), aminoglycoside resistance genes (aac(3)-IIa, aadA2, aadA5, ant(3")-Ia, aph(3")-Ib, aph(3′)-Ia, aph(6)-Id), tetracycline resistance genes (tetB, tetA), trimethoprim resistance genes (dfrA17, dfrA1, dfrA5, dfrA12), sulfonamide resistance genes (sul1, sul2, sul3), macrolide/lincosamide/streptogramin resistance genes (mphB, lnuF, ermC, mefC), quinolone resistance genes (qnrB19, qnrB5, qnrS1, qnrS2), and others. Additionally, point mutations in gyrA, parC, and parE were associated with fluoroquinolone resistance.
Extended-spectrum beta-lactamase-producing Enterobacterales in human health: Experience from the tricycle project, Ghana.
The study identified a high prevalence of ESBL-E carriage among pregnant women in Ghana, with blaCTX-M-15 being the most prevalent ESBL gene. The study also found that 50% of ESBL-E isolates were multidrug resistant, highlighting the urgent need for public health interventions to control the spread of AMR.
Genome and antibiotic resistance characteristics of Shigella clinical isolates in Fujian Province, Southeast China, 2005-2019.
The study identified various AMR genes in Shigella isolates from Fujian Province, including beta-lactamases (bla TEM-1, bla OXA-1, bla CTX-M-14, bla CTX-M-15, bla CTX-M-55, bla CTX-M-64), macrolide resistance genes (mphA, ermB), tetracycline resistance genes (tetA, tetB), aminoglycoside resistance genes (aadA, aph(3')-Ib, aac(3)-IId), chloramphenicol resistance gene (catA1), and sulfonamide/trimethoprim resistance genes (sul1, sul2, dfrA1, dfrA12, dfrA14, dfrA17).
The role of New World vultures as carriers of environmental antimicrobial resistance.
The study identified several antimicrobial resistance genes (ARGs) in environmental samples collected from New World vultures, including blaTEM, sul1, ermA, ermF, tetA, and tetB, which confer resistance to beta-lactams, sulfonamides, macrolides, and tetracyclines. These genes were detected in Escherichia coli, enterococci, and Salmonella spp. across different sampling sites and seasons.
Escherichia coli from six European countries reveals differences in profile and distribution of critical antimicrobial resistance determinants within One Health compartments, 2013 to 2020.
The study identified various AMR genes in E. coli isolates from different sources in six European countries, highlighting differences in resistance profiles and the prevalence of specific resistance mechanisms such as beta-lactamases, quinolone resistance genes, and tetracycline resistance genes.
Genomic perspective on the bacillus causing paratyphoid B fever.
The study identified mutations in the gyrA gene associated with reduced susceptibility to fluoroquinolones in Salmonella enterica serotype paratyphi B strains.
Fecal carriage of ESBL-producing E. coli and genetic characterization in rural children and livestock in the Somali region, Ethiopia: a one health approach.
The study identified bla CTX-M-15 as the most prevalent ESBL gene in both human and animal E. coli isolates, along with other resistance genes such as bla TEM-1B, bla OXA-1, and various aminoglycoside, sulfonamide, and trimethoprim resistance genes. Mutations in gyrA, parC, and parE were also associated with fluoroquinolone resistance.
Epidemiology and Molecular Characterisation of Multidrug-Resistant Escherichia coli Isolated from Cow Milk.
The study identified several AMR genes in multidrug-resistant E. coli isolates from cow milk, including bla TEM, bla CTX-M, bla OXA-1, bla OXA-2, bla CMY-1, tet A, tet B, tet D, sul -1, and sul -2, which confer resistance to various antibiotics.
Harnessing CRISPR interference to resensitize laboratory strains and clinical isolates to last resort antibiotics.
The study demonstrates that CRISPR interference (CRISPRi) can re-sensitize laboratory strains and clinical isolates to last-resort antibiotics by repressing the expression of specific antibiotic resistance genes (ARGs).
Genomic insights into the dynamic antibiotic resistance landscape of Vibrio cholerae during the Cholera outbreak 2022 in Odisha, India.
Antibiotic Resistance in Mammalian Wild Game: A Meta-Analysis
The study presents a comprehensive meta-analysis of antibiotic resistance in bacteria isolated from mammalian wild game, highlighting the prevalence of various AMR genes and mutations across different bacterial species.
The presence of antibiotic-resistant bacteria at four Norwegian wastewater treatment plants: seasonal and wastewater-source effects.
The study identified the presence of resistance genes ermB, tetA, and tetM in wastewater treatment plants in Norway, highlighting their persistence in effluent and the need for advanced treatment processes to mitigate their environmental spread.
Prevalence and Zoonotic Risk of Multidrug-Resistant Escherichia coli in Bovine Subclinical Mastitis Milk: Insights Into the Virulence and Antimicrobial Resistance.
The study identified multidrug-resistant Escherichia coli in bovine subclinical mastitis milk, harboring genes blaSHV, CITM, tetA, and aac(3)-IV, which confer resistance to ampicillin, amoxicillin, tetracycline, and gentamycin, respectively. These isolates showed multidrug resistance and were closely related to disease-causing strains from various sources.
Whole-genome sequencing-based characterization of Salmonella enterica Serovar Enteritidis and Kentucky isolated from laying hens in northwest of Iran, 2022-2023.
The study identified the presence of a multidrug-resistant (MDR) Salmonella enterica serovar Kentucky ST198 clone with high-level ciprofloxacin resistance due to double mutations in gyrA (S83F, D87N) and parC (T57S, S80I) genes. The aminoglycoside resistance gene aac(6′)-Iaa was the most frequently detected gene, but it did not confer resistance to aminoglycosides. Other resistance genes included tetA, floR, sul1, dfrA1, and aph(3′)-Ia.
Pandemic one health clones of Escherichia coli and Klebsiella pneumoniae producing CTX-M-14, CTX-M-27, CTX-M-55 and CTX-M-65 ESβLs among companion animals in northern Ecuador.
The study identifies CTX-M-55, CTX-M-65, CTX-M-27, and CTX-M-14 ESβL-producing E. coli and K. pneumoniae in companion animals in Ecuador, highlighting their global One Health significance and the need for surveillance programs.
Highly drug resistant clone of Salmonella Kentucky ST198 in clinical infections and poultry in Zimbabwe.
The study identifies multiple AMR genes and mutations in Salmonella Kentucky ST198 strains from Zimbabwe, highlighting their multidrug resistance and the presence of specific resistance mechanisms such as blaCTX-M-14.1 and mutations in gyrA and parC.
Emerging Resistance and Virulence Patterns in Salmonella enterica: Insights into Silver Nanoparticles as an Antimicrobial Strategy.
The study identified various AMR genes in Salmonella enterica isolates, including blaTEM-1, aadA1, aadA2, aadA5, ant(2")-Ia, aph(3")-Ib, aph(6)-Id, mph(A), tet(A), tet(B), sul1, sul2, sul3, qnrA1, qnrB19, dfrA5, dfrA12, dfrA17, cmlA1, and cmlA5, which confer resistance to β-lactams, aminoglycosides, tetracyclines, sulfonamides, fluoroquinolones, trimethoprim, and chloramphenicol.
The Difference a Year Can Make: How Antibiotic Resistance Mechanisms in Pseudomonas aeruginosa Have Changed in Northwestern Transylvania.
The study identified an increase in multidrug-resistant (MDR) and extensively drug-resistant (XDR) Pseudomonas aeruginosa isolates in Northwestern Transylvania, Romania, between 2022 and 2023. Key AMR genes included bla OXA-50, sul1, ermB, mexA, mexB, bla VIM-1, aac(6′)-II, ant(4′)-Ia, aac(3)-I, aac(6′)-Im, aph(2″)-Ib, tetA, tetC, tetK, qnrB, ermC, mphC, fosA, nfsA, nfsB, ampC, and TEM-1.
Assessment of Antibiotic Resistance Among Isolates of Klebsiella spp. and Raoultella spp. in Wildlife and Their Environment from Portugal: A Positive Epidemiologic Outcome.
The study identified a single multidrug-resistant (MDR) and extended-spectrum beta-lactamase (ESBL)-producing K. pneumoniae isolate from soil samples carrying multiple resistance genes, including bla CTX-M-15, bla TEM-1, bla SHV-28, bla OXA-1, qnr B1, oqx A, oqx B19, aac (6′)-Ibcr, sul 2, dfr A14, tet A, aph (6)-Id, aph (3″)-Ib, acr D, cat B3, and Int I1.
Protozoa-enhanced conjugation frequency alters the dissemination of soil antibiotic resistance.
Protozoa enhance the conjugation frequency of antibiotic resistance genes (ARGs) in soil microbial communities, increasing the transfer of ARGs such as blaTEM and tetA. This process is linked to increased reactive oxygen species (ROS) production and membrane permeability.
Cockroaches as Reservoirs, Vectors, and Potential Sentinels of Multidrug-Resistant Bacteria in Ugandan Communities: A Retrospective Analysis.
The study identified tetracycline and sulfonamide resistance genes (tetA, sul1, sul2) in Escherichia coli and tetracycline resistance genes (tetM, tetL) in Enterococcus spp. from cockroaches in Ugandan communities.
Prevalence and antibiotic resistance of Escherichia coli in urban and peri-urban garden ecosystems in Bangladesh.
The study identified the presence of blaTEM and tetA genes in E. coli isolates from urban and peri-urban gardens in Bangladesh, contributing to their resistance to ampicillin and tetracycline, respectively.
Phenotypic and genotypic characterization of Aeromonas hydrophila isolated from freshwater fishes at Middle Upper Egypt.
The study identified the presence of blaTEM, qnrA, sul1, and tetA genes in multidrug-resistant Aeromonas hydrophila isolates from freshwater fishes in Middle Upper Egypt, highlighting the significance of these genes in antimicrobial resistance.
Circulation of a Unique Klebsiella pneumoniae Clone, ST147 NDM-1/OXA-48, in Two Diverse Hospitals in Calabria (Italy).
The study identifies multiple AMR genes, including bla OXA-48, bla NDM-1, bla CTX-M-15, and bla SHV, in K. pneumoniae strains from two hospitals in Calabria, Italy, highlighting the presence of multidrug-resistant clones.
Molecular characterization of resistance and biofilm genes of ESKAPE pathogens isolated from clinical samples: examination of the effect of boric acid on biofilm ability by cell culture method.
The study identified various AMR genes in ESKAPE pathogens, including vanA and vanC for vancomycin resistance, blaKPC and blaOXA-48 for carbapenem resistance, and others related to tetracycline, sulfonamide, quinolone, and aminoglycoside resistance. Additionally, biofilm-related genes such as icaA, icaD, gelE, asa1, and esp were detected in Staphylococcus and Enterococcus spp. Quorum sensing genes LasI and LasR were found in Pseudomonas aeruginosa, and biofilm production genes like mrkA, wbbM, wzm, and luxS were identified in Klebsiella pneumoniae.
Drug resistance and genotyping studies of Salmonella Enteritidis isolated from broiler chickens in Iran.
The study identified several AMR genes in Salmonella Enteritidis isolates from broiler chickens in Iran, including bla TEM, tet A, tet B, sul 1, and str A/B, which conferred resistance to various antibiotics.
Fecal carriage and molecular characterization of carbapenem-resistant Enterobacteriaceae from hospitalized children in a tertiary hospital of Shandong, China.
The study identified bla NDM-1, bla NDM-5, and bla OXA-1 as the most prevalent carbapenemase genes in CRE isolates from hospitalized children in Shandong, China. Additional resistance genes such as bla CTX-M-55, bla CTX-M-15, sul 1, tet A, and mcr-1.26 were also characterized.
Whole-genome sequencing-based species classification, multilocus sequence typing, and antibiotic resistance mechanisms of the clinical Aeromonas complex.
The study identified multiple beta-lactamase genes, including bla NDM-1, bla PER-3, and bla OXA-1, along with other resistance genes such as aac(6′)-Ib-cr6, aph(3″)-Ib, and floR, which contribute to resistance against various antibiotics in Aeromonas isolates.
Broiler litter moisture and trace metals contribute to the persistence of Salmonella strains that harbor large plasmids carrying siderophores.
The study identified several antimicrobial resistance genes in Salmonella strains isolated from broiler litter, including aadA1, aac(3)-IV, aph(3′)-Ia, aph(4)-Ia, dfrA14, floR, sul1, tetA, sul2, merRTPCA, qacE, aph(3″)-Ib, aph(6)-Id, pcoABCDRE, silP, and silE. These genes were found on various plasmids and contributed to resistance against multiple antibiotics such as streptomycin, chloramphenicol, sulfamethoxazole, tetracycline, mercury, quaternary ammonium compounds, copper, and silver.
Molecular identification of tetracycline resistance genes in Escherichia coli isolates from internal organs of swine sold on Abakaliki, Nigeria.
The study identified the presence of tetracycline resistance genes tetA and tetB in E. coli isolates from swine internal organs in Abakaliki, Nigeria. These genes were found in 75% and 62.5% of the tetracycline-resistant isolates, respectively.
Zoonotic potential of uropathogenic Escherichia coli lineages from companion animals.
The study identified several antimicrobial resistance genes in uropathogenic E. coli strains from companion animals, including blaTEM-1b, sul1, sul2, dfrA1_10, dfrA17_1, dfrA1_8, dfrA7_5, gyrA_S83L, tetA, tetB, aph(6)-Id, aph(3'')-Ib, ant(3'')-Ia, blaCTX-M-15, blaTEM-106, blaSHV-102, and blaCMY-2. These genes confer resistance to various antibiotics such as penicillins, sulfonamides, trimethoprim, quinolones, tetracyclines, streptomycin, and cephalosporins.
A Snapshot of Antimicrobial Resistance in Semi-Wild Oryx: Baseline Data from Qatar.
The study identified tetracycline resistance genes tetA and tetB, as well as bla CTX-M and bla TEM-1 for beta-lactam resistance in E. coli isolates from semi-wild oryx in Qatar. Whole genome sequencing revealed additional resistance mechanisms, including mutations in soxR associated with tetracycline resistance.
Prevalence, antibiotic resistance, virulence and antimicrobial resistance gene profiles of Salmonella species recovered from retail beef and poultry processing environments.
The study identified the presence of resistance genes bla TEM, tetA, and sul1 in Salmonella isolates from retail beef and poultry processing environments, indicating high levels of antimicrobial resistance.
Strict relationship between phenotypic and plasmid-associated genotypic of multidrug-resistant Escherichia coli isolated from Taihe Black-Boned Silky Fowl farms.
The study identified multiple AMR genes in multidrug-resistant E. coli isolates from Taihe Black-Boned Silky Fowl farms, including blaTEM, blaOXA-10, tetA, tetR, floR, cmlA, qnrS, strA, strB, aadA, aac(3)-IId, sul, and dfrA. These genes were associated with resistance to beta-lactams, tetracyclines, chloramphenicol, fluoroquinolones, aminoglycosides, and sulfonamides.
High prevalence of plasmid-mediated Fosfomycin resistance in waterfowl-derived Escherichia coli strains: insights into genetic context and transmission dynamics in China.
The study identifies fosA3 as a prevalent plasmid-mediated fosfomycin resistance gene in waterfowl-derived E. coli strains, along with other resistance genes such as blaCTX-M-55, blaNDM-5, mcr-1.1, tetA, floR, qnrS, sul2, and aphA1. These genes contribute to multidrug resistance and highlight the importance of monitoring their spread.
Whole-genome-based characterization of Escherichia albertii strains isolated from paediatric diarrhoeal cases in Kolkata, India.
The study identified several antimicrobial resistance genes in Escherichia albertii isolates, including beta-lactamases (bla CTX-M-55, bla TEM-105), quinolone resistance genes (qnrS1, qnrB32), sulfonamide resistance gene (sul2), tetracycline resistance genes (tetA, tetR), and trimethoprim resistance gene (dfrA1).
Antimicrobial Resistance in Livestock and Its Impact on Public Health
The study highlights the role of livestock environments as reservoirs for antimicrobial resistance genes, identifying blaCTX-M-1, tetA, qnrS, and sul2 as key contributors to resistance in Escherichia coli, Salmonella spp., and Staphylococcus spp.
Genomic analyses reveal presence of extensively drug-resistant Salmonella enterica serovars isolated from clinical samples in Guizhou province, China, 2019-2023.
The study identified multiple antimicrobial resistance genes and mutations in XDR Salmonella isolates from Guizhou, China, including bla TEM-1, bla CTX-M-55, qnrS1, oqxA, aac(6')-Ib-cr, tetA, mcr-1.1, and bla NDM-1, as well as mutations in gyrA and parC associated with fluoroquinolone resistance.
Ecological prevalence and genomic characterization of Salmonella isolated from selected poultry farms in Jiangxi province, China.
The study identified 61 antimicrobial resistance genes (ARGs) in Salmonella isolates from poultry farms in Jiangxi, China, including aph(3')-Ia, qnrS1, aph(3'')-Ib, tetA, bla TEM, bla SHV, and bla CTX-M, which conferred resistance to aminoglycosides, quinolones, tetracyclines, and beta-lactams.
An experimental study of levamisole incorporated diet on fish health and resistance against Pseudomonas aeruginosa isolated from Oreochromas niloticus.
The study identified the presence of antibiotic resistance genes blaTEM, tetA, and sul1 in Pseudomonas aeruginosa isolates from Nile tilapia, indicating resistance to tetracycline and sulfonamides.
Intestinal and Extraintestinal Pathotypes of Escherichia coli Are Prevalent in Food Prepared and Marketed on the Streets from the Central Zone of Mexico and Exhibit a Differential Phenotype of Resistance Against Antibiotics.
The study identifies multiple antibiotic resistance genes in E. coli isolates from street-prepared food in Mexico, including strA, sul1, catA1, floR, qnrS, and tetA, which confer resistance to streptomycin, sulfonamides, chloramphenicol, quinolones, and tetracycline.
Wild Birds as Drivers of Salmonella Braenderup and Multidrug Resistant Bacteria in Wetlands of Northern Italy.
The study identifies several AMR genes in bacterial isolates from wild aquatic birds in Northern Italy, including beta-lactamases (blaTEM, blaCMY-1, blaCMY-2, blaNDM, blaKPC), colistin resistance genes (mcr-2, mcr-3, mcr-4), tetracycline resistance genes (tetA, tetB, tetC, tetL, tetM, tetK), macrolide resistance genes (ermB, vatD, vgA, msrC), vancomycin resistance genes (vanC1, vanC2, vanM, vanG), sulfonamide resistance genes (sul1, sul2, sul3), aminoglycoside resistance genes (aac(3), aac(6')-Ib, aph(3')-Ia, armA, rmtB, rmtC, rmtF), and nitrofurantoin resistance genes (nfsA, nfsB).
Antimicrobial Resistance in Nigeria: A Comprehensive Review of Environmental, Food, and Clinical Impacts
The study identifies several AMR genes, including bla CTX-M-15, floR, and various tetracycline and sulfonamide resistance genes, highlighting the spread of multidrug-resistant bacteria in Nigeria's environment, food supply chain, and clinical settings.
Comparative genomic analysis of Flavobacterium species causing columnaris disease of freshwater fish in Thailand: insights into virulence and resistance mechanisms.
The study identified a tetracycline resistance gene (tetA_2) in a F. covae isolate and mutations in the quinolone resistance-determining regions of gyrA associated with decreased susceptibility to quinolones and fluoroquinolones in Flavobacterium species causing columnaris disease in Thailand.
Whole genome sequencing reveals virulence-mobile element linkages and phylogenetic diversity in multidrug-resistant Escherichia coli from Nigeria.
The study identified multidrug-resistant Escherichia coli isolates from Nigeria, highlighting the presence of virulence genes and mobile genetic elements, along with specific mutations in gyrA and parC that confer resistance to fluoroquinolones.
Transmissible antimicrobial resistance in Escherichia coli isolated from household drinking water in Ibadan, Nigeria.
The study identified several AMR genes in E. coli isolates from household water in Ibadan, Nigeria, including blaTEM-1B, dfrA14, tetA, qnrS1, and mcr-1, highlighting the potential for horizontal gene transfer and the risk of AMR spread in the environment.
Molecular characterization of multidrug-resistant Escherichia coli in the Greater Accra Region, Ghana: a 'One Health' approach.
The study identified multidrug-resistant Escherichia coli isolates carrying various AMR genes, including blaTEM-1B, tetA, sul2, aph(3'')-Id, dfrA14, qnrS1, and blaCTX-M-15, highlighting the spread of resistance mechanisms in the Greater Accra Region.
Genomic Insights of Antibiotic-Resistant Escherichia coli Isolated from Intensive Pig Farming in South Africa Using 'Farm-to-Fork' Approach.
The study identified multiple antibiotic resistance genes and mutations in E. coli isolates from intensive pig farming in South Africa, highlighting the spread of resistance across the pork production continuum.
Emergence and characteristics of multidrug-resistant Salmonella enterica subspecies enterica serovar Infantis harboring the pESI plasmid in chicken slaughterhouses in South Korea.
The study identifies multidrug-resistant Salmonella enterica subsp. enterica serovar Infantis isolates harboring the pESI plasmid, which carries genes such as bla CTX-M-65, aadA1, dfrA14, sul1, tetA, and floR, leading to resistance against multiple antibiotics including third-generation cephalosporins.
Integrated genomic-epigenomic-transcriptomic analyses reveal adaptive mechanisms of colistin and carbapenem resistance in Klebsiella pneumoniae and Enterobacter isolates
The study identifies multiple AMR genes and mutations associated with colistin and carbapenem resistance in Klebsiella pneumoniae and Enterobacter isolates, including beta-lactamases, fosfomycin resistance genes, and efflux pumps. Mutations in ompK35 were found to contribute to carbapenem resistance.
Retrospective analysis of antimicrobial resistance of Salmonella spp. isolated from livestock and its environment in Thailand.
The study identified several AMR genes in Salmonella isolates from livestock and their environment in Thailand, including aadA1, aadA2, aadB, aac(6')-Ia, blaTEM, tetA, tetB, catA, catB, cmlA, sulI, and dfrA1, which confer resistance to various antibiotics such as aminoglycosides, beta-lactams, tetracyclines, chloramphenicol, sulfamethoxazole, and trimethoprim.
Molecular Identification and Antimicrobial Resistance Characteristics of Extended-Spectrum Beta-Lactamase Producing Klebsiella pneumoniae Isolated from Captive Wild and Migratory Birds.
The study identified extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae in captive wild and migratory birds in Bangladesh, highlighting the presence of resistance genes such as bla TEM-1&2, bla SHV-1, bla OXA-1,4&30, strA, tetA, and sul1, which contribute to multidrug resistance.
Occurrence and Drivers of Antibiotic Resistance Genes Carried by Bacteriophages in Soils Following Different Fertilization Treatments.
The study identified 19 pARG subtypes in soils with different fertilization treatments, highlighting the impact of organic fertilizers on the diversity and abundance of antibiotic resistance genes carried by bacteriophages.
Characterizing antimicrobial resistance and plasmidome diversity in Escherichia coli from imported frozen broiler chicken in the United Arab Emirates.
The study identified several AMR genes in E. coli isolates from imported frozen broiler chicken in the UAE, including bla CTX-M-55, bla CTX-M-8, bla TEM-1B, aadA1, qnrS1, tetA, sul1, sul2, and sul3. These genes conferred resistance to various antibiotics such as beta-lactams, aminoglycosides, fluoroquinolones, and sulfonamides.
Multidrug-resistant Klebsiella pneumoniae ST70 harboring bla(NDM) in a migratory Penguin.
The study identifies multiple antimicrobial resistance genes in a multidrug-resistant Klebsiella pneumoniae ST70 isolate from a Magellanic Penguin, highlighting the potential of migratory penguins as vectors of antimicrobial-resistant microorganisms.
Variants of β-lactamase-encoding genes are disseminated by multiple genetically distinct lineages of bloodstream Escherichia coli.
The study identified multiple β-lactamase genes, including bla TEM-1, bla CTX-M-15, and bla OXA-1, along with other AMR genes such as aadA5, aph(3")-Ib, aph(6)-Id, mphA, sul1, sul2, tetA, dfrA17, and aac(6')-Ib-cr5, which confer resistance to various antimicrobial classes in bloodstream E. coli isolates.
Emergence of highly virulent Aeromonas dhakensis in channel catfish aquaculture: Genomic insights into pathogenicity and antimicrobial resistance.
The study identified 60 antibiotic resistance genes in the highly virulent Aeromonas dhakensis strain CWH5, including genes conferring resistance to multiple drug classes such as beta-lactams, tetracyclines, sulfonamides, and macrolides.
Whole-Genome Sequencing and Bioinformatics Analysis of ESBL-producing Klebsiella pneumoniae in a Ghanaian teaching hospital.
The study identified multiple beta-lactamase genes, including bla SHV, bla CTX-M-15, bla TEM-1B, and bla OXA-1, as well as a variety of other resistance genes such as aac(3)-IIa, aac(6')-Ib-cr, aph(3'')-Ib, aph(6)-Id, aadA1, qnrB1, qnrB4, qnrB2, qnrB19, sul2, sul1, dfrA14, dfrA15, OqxA, OqxB, fosA, qacE, tetA, and tetD. Mutations in ompK36 and ompK37 were also found to contribute to reduced susceptibility to cephalosporins and carbapenems.
Pan-drug, colistin, streptomycin, erythromycin, clindamycin resistant Salmonella enterica serovars isolated from slaughtered cattle and human in mansoura, Egypt.
The study identified multiple AMR genes in Salmonella isolates, including aadA1, tetA, sul1, and aac(3)-IV, which conferred resistance to streptomycin, tetracycline, sulfamethoxazole/trimethoprim, and gentamicin, respectively.
Genomic features of three major diarrhoeagenic Escherichia coli pathotypes in India.
The study identifies a variety of acquired antimicrobial resistance (AMR) genes in diarrhoeagenic Escherichia coli (DEC) strains from India, highlighting the prevalence of resistance to multiple antibiotic classes, including aminoglycosides, beta-lactams, sulfonamides, and tetracyclines. Key AMR genes include blaTEM-105, strB, strA, mphA, sul1, sul2, addA1-pm, tetA, tetB, blaCTX-M15, blaCTX-M27, and blaDHA-1. Additionally, mutations in the quinolone resistance-determining regions (QRDRs) of gyrA and parC were found to contribute to fluoroquinolone resistance.
Overlooked Enterobacterales as hosts of antimicrobial resistance in aquatic environments.
The study identified several AMR genes in environmental Enterobacterales isolates, including blaTEM-1, blaCTX-M, tetA, tetB, tetC, tetL, tetM, sul1, sul2, qnrS, ermB, and mefA, which conferred resistance to various antibiotics such as ampicillin, ceftazidime, cefepime, tetracycline, trimethoprim-sulfamethoxazole, ciprofloxacin, and erythromycin.
Biofilm Formation and Antibiotic Resistance Genes of Escherichia coli From Poultry Farms and Clinical Samples.
The study identified several AMR genes in E. coli isolates from poultry and clinical samples, including blaTEM, gyrA, gyrB, qnrB, qnrB4, qnrS, blaCTX-M, sul1, sul2, tetA, and tetB. These genes conferred resistance to various antibiotics such as beta-lactams, fluoroquinolones, sulfonamides, and tetracyclines. High levels of resistance were observed against tylosin, neomycin, tetracycline, ampicillin, doxycycline, ciprofloxacin, and trimethoprim/sulfamethoxazole.
Isolation and Molecular Characterization of Antimicrobial-Resistant Bacteria from Vegetable Foods.
The study identified several antimicrobial resistance genes in Enterobacteriaceae isolated from vegetables, including TEM, CTX-M IV, SHV, OXA, CMY II, DHA, tetA, tetW, sul-I, and qnrD, which confer resistance to beta-lactams, tetracyclines, sulfonamides, and quinolones.
Decoding past microbial life and antibiotic resistance in İnonü Cave's archaeological soil.
The study identified the presence of the tetracycline resistance gene tetA in Chalcolithic samples, the class 1 integron intl1 in Early Bronze Age samples, and the oxacillinase gene OXA58 in Late Bronze Age samples.
Epidemiological and biological characteristics of IncR plasmids as multihost antibiotic resistance carriers.
The study characterizes various AMR genes carried by IncR plasmids, highlighting their role in the dissemination of resistance to carbapenems, cephalosporins, fluoroquinolones, aminoglycosides, and tetracyclines.
Monitoring, surveillance, antimicrobial resistance and genetic diversity analysis of non-typhoidal Salmonella in South Africa from 1960-2023 from animal and animal products.
The study identified several AMR genes in Salmonella isolates from South Africa, including blaPSE, blaSHV, qnrS, tetA, qnrA, cat1, blaCMY-2, and qnrB, which were associated with resistance to various antibiotics such as ceftriaxone, chloramphenicol, tetracycline, and others.
Fecal carriage of resistant Escherichia coli in livestock in Algeria: emergence of NDM and OXA-181.
The study identified the presence of 3GC-resistant E. coli in livestock in Algeria, with the detection of various resistance genes including bla CTX-M, bla NDM-1, bla OXA-181, bla CMY, tet A, aac(6')-Ib, and intI1. These genes contribute to resistance against multiple antibiotics, highlighting the need for monitoring and control strategies.
Epidemiology of potential source, risk attribution of Clostridium perfringens from Egyptian broiler farms and genetic diversity of multidrug resistance strains.
The study identified multiple AMR genes in Clostridium perfringens isolates from Egyptian broiler farms, including aminoglycoside, beta-lactam, macrolide, quinolone, sulfonamide, tetracycline, and trimethoprim resistance genes. High prevalence of multidrug-resistant strains was observed.
Epidemiology of potential source, risk attribution of Clostridium perfringens from Egyptian broiler farms and genetic diversity of multidrug resistance strains.
The study identified multiple AMR genes in Clostridium perfringens isolates from Egyptian broiler farms, including aminoglycoside, beta-lactam, macrolide, quinolone, sulfonamide, tetracycline, and trimethoprim resistance genes. High prevalence of multidrug-resistant strains was observed.
Ecology-based approach to predict no-effect antibiotic concentrations for minimizing environmental selection of resistance.
The study presents a framework to predict no-effect concentrations for antibiotic resistance selection in the environment by integrating minimum inhibitory concentration (MIC) data with resistance-related fitness costs. It identifies various AMR genes and their resistance profiles through competition experiments.
Identification and preclinical efficacy evaluation of two lytic bacteriophages targeting highly virulent and multidrug-resistant Klebsiella pneumoniae.
The study identifies two lytic bacteriophages, vB_KpnP_XY3 and vB_KpnP_XY4, effective against multidrug-resistant Klebsiella pneumoniae. These phages demonstrate broad temperature and pH tolerance, chloroform resistance, and potent lytic activity against MDR K. pneumoniae strains, significantly reducing bacterial load and inflammation in a murine pneumonia model.
Clonal Dissemination of Pandrug-Resistant Klebsiella pneumoniae ST392KL27 in a Tertiary Care Hospital in Mexico.
The investigation of bacteria in the oral of Trichomonas gallinae infected pigeons and the antibiotic resistance analysis of Klebsiella pneumoniae clinical isolates from farm pigeons in Shandong Province of China.
The study identified multiple antibiotic resistance genes in Klebsiella pneumoniae isolates from farm pigeons in Shandong Province, including bla-SHV, bla-TEM, bla-CTX-M-9, qnrB, tetA, and aac(6')-Ib, highlighting the presence of multidrug-resistant strains.
Antibiotic resistance and novel Sequence Types of Klebsiella spp. in human, animal, and food sources: a One Health perspective from Northern Nigeria.
The study identified various AMR genes in Klebsiella spp. isolates from human, animal, and food sources, including strB, qnrS1, sul2, tetA, dfrA14, blaTEM-1, and blaSHV-11, which conferred resistance to multiple antibiotics.
Dissemination dynamics of colistin resistance genes mcr-9 and mcr-10 across diverse Inc plasmid backbones.
The study characterizes the dissemination of colistin resistance genes mcr-9 and mcr-10 across diverse Inc plasmid backbones in Enterobacter species, highlighting their co-occurrence with other resistance genes and their global distribution.
Multidrug-Resistant Escherichia coli Associated with Respiratory and Systemic Infection in a Domestic Rabbit in Romania: First Confirmed Case.
The study reports the first confirmed case of multidrug-resistant Escherichia coli in a domestic rabbit in Romania, highlighting its pathogenic potential and the need for improved antimicrobial stewardship.
Multidrug-Resistant pESI-Harboring Salmonella enterica Serovar Muenchen Sequence Type 82 in Poultry and Humans, Israel, 2020-2023.
In-depth characterization of virulence traits, pathogenicity, antibiogram, and antibiotic resistance genes of MDR Vibrio parahaemolyticus retrieved from shrimp.
The study identified multiple antibiotic resistance genes in MDR Vibrio parahaemolyticus strains isolated from shrimp, including bla TEM, bla OXA, tet A, aad A, erm B, and sul 1, which confer resistance to various antibiotics.
Genetic diversity, virulence genes, antimicrobial resistance, and biofilm formation of Klebsiella pneumoniae isolated from bovine mastitis milk in South Korea.
The study identified several AMR genes in K. pneumoniae isolates from bovine mastitis milk in South Korea, including blaSHV, strA, strB, sulI, sulII, tetA, tetB, tetC, floR, dfrXII, blaTEM, blaCTX-M, and blaOXA, which confer resistance to various antibiotics such as ampicillin, gentamicin, trimethoprim/sulfamethoxazole, tetracycline, chloramphenicol, and others.
Antimicrobial resistance profiles and genomic insights of phenotypically extended spectrum β-lactamase-positive Klebsiella pneumoniae from cattle farms.
The study identifies multiple AMR genes, including bla TEM, bla SHV, bla AmpC, qnrS, and tetA, in phenotypically ESBL-positive K. pneumoniae isolates from cattle farms in Punjab, India. These genes confer resistance to various antibiotics, highlighting the potential for AMR spread in livestock environments.
Resistance, virulence and genetic diversity of Salmonella Typhimurium in South Africa (1999-2021).
The study identified several AMR genes in Salmonella Typhimurium isolates from South Africa, including beta-lactamases (bla PSE, bla CMY-2, bla TEM, bla SHV), sulfonamide resistance genes (sul1, sul2, sul3), fluoroquinolone resistance genes (qnrA, qnrB, qnrS), tetracycline resistance genes (tetA, tetB), and trimethoprim resistance genes (dfrXI, dfrXII).
Molecular identification of antibiotic-resistant and virulent Escherichia coli and Staphylococcus aureus isolated from dogs in Southern Benin.
The study identified several antibiotic resistance genes in Escherichia coli and Staphylococcus aureus isolated from dogs in Southern Benin, including blaTEM, tetA, strA-strB, tetK, tetM, and blaZ, which confer resistance to penicillin, tetracycline, and streptomycin.
Antibiotic resistance and pathogenicity of Shiga-toxin-producing Escherichia coli (STEC) and non-STEC isolated from goats in the Mekong Delta, Vietnam.
The study identified several antibiotic resistance genes, including blaampC, tetA, sulII, qnrA, aadA1, and czcD, in E. coli isolates from goats in the Mekong Delta, Vietnam. It also detected virulent genes such as stx1, stx2, eae, and hlyA.
Zoonotic potential of methicillin-resistant Staphylococcus aureus isolated from pets and their owners in Bangladesh.
The study identified methicillin-resistant Staphylococcus aureus (MRSA) in pets and their owners in Bangladesh, highlighting the zoonotic potential of MRSA. Key AMR genes included mecA, tetA, tetK, tet(38), and blaZ, which conferred resistance to methicillin, tetracycline, and penicillin.
Azithromycin resistance in nontyphoidal Salmonella in an urban informal settlement in Nairobi, Kenya.
The study identified several AMR genes in nontyphoidal Salmonella isolates, including aac(6')-Iaa, aph(3")-Ib, aph(6)-Id, ant(3")-Ia, sul1, sul2, dfrA1, dfrA8, tetA, mph(A), bla CTX-M-3, bla TEM-135, bla TEM-1B, and bla TEM-1C. These genes conferred resistance to various antibiotics such as aminoglycosides, sulfonamides, tetracycline, macrolides, and beta-lactams.
Multidrug-resistant Pseudomonas aeruginosa: Pathogenesis, resistance mechanisms, and novel therapeutic strategies.
The paper discusses the multidrug resistance mechanisms of Pseudomonas aeruginosa, including beta-lactamases, aminoglycoside modifying enzymes, efflux pumps, and mutations in porin genes. It highlights the role of these mechanisms in antibiotic resistance and the challenges they pose in treating infections.
Acquisition of novel antibiotic resistance genes by the bacterial predator Bacteriovorax sp. As-1.
Bacteriovorax sp. As-1 exhibits resistance to multiple antibiotics, primarily due to mutations in the gyrA gene, specifically S90Y and G94R, which are associated with reduced fluoroquinolone susceptibility.
Pathogenic potential of amoxicillin-clavulanic acid resistant Klebsiella pneumoniae isolated from aquatic environment: a study of multidrug resistance and virulence.
The study identified several AMR genes in AMC-resistant K. pneumoniae isolates from aquatic environments, including bla TEM, bla SHV, bla CTX-M, bla NDM, bla OXA-48, bla CMY, qnr S, qnr B, tet A, tet B, sul 1, dfr A12, intl 1, intl 2, mrk D, ecp A, and iuc C. These genes were associated with resistance to multiple antibiotics, highlighting the complex resistance profiles of these isolates.
Genetic diversity and antimicrobial resistance profiles of Salmonella enterica in the broiler supply chain in Harare, Zimbabwe: tracking transmission from farm to table.
The study identified several AMR genes and mutations in Salmonella enterica isolates from the broiler supply chain in Zimbabwe, including fosA7.2, qnrB19, aadA1, aph(3'')-Ib, aph(6)-Id, aac(3)-Id, fosA3, sul1, sul3, tetA, cmlA1, blaCMY-2, blaTEM-1B, blaCTX-M-14, and mutations in gyrA and parC. These genes and mutations confer resistance to various antibiotics, including fosfomycin, fluoroquinolones, aminoglycosides, sulfonamides, tetracyclines, chloramphenicol, and beta-lactams.
Prevalence and Genetic Characterization of Antimicrobial-resistant Escherichia coli from Wild Boar Meat in Japan.
The study identified antimicrobial-resistant Escherichia coli in wild boar meat in Japan, with resistance genes including blaTEM, strA, strB, aacC2, aphA1, tetA, and tetB.
Escherichia coli O157:H7 prevalence in Upper Egypt: impacts on food safety and human Health, with a protection trial using natural antibacterial Piper cubeba.
The study identified blaTEM, tetA, and Aada1 as the most common resistance genes in multidrug-resistant E. coli O157:H7 isolates in Upper Egypt. These genes confer resistance to beta-lactams, tetracyclines, and aminoglycosides, respectively.
Emerging threat of antimicrobial resistance determinants and plasmid replicon types acquisition by Escherichia coli of poultry and other food-producing animal origin in China: local findings with global implications.
The study identifies multiple antimicrobial resistance genes in Escherichia coli from poultry and other food-producing animals in China, highlighting the prevalence of beta-lactamases, tetracycline resistance genes, aminoglycoside modifying enzymes, quinolone resistance genes, and sulfonamide resistance genes.
Genomic epidemiology reveals statewide dispersal of clinical Shiga toxin-producing Escherichia coli and their antimicrobial resistome.
The study identifies 93 unique antimicrobial resistance (AMR) determinants in 1,655 clinical Shiga toxin-producing Escherichia coli (STEC) isolates from New York State, revealing extensive diversity in AMR genes and plasmid replicon types. Key AMR genes include blaEC, mdtM, acrF, ermD, sul2, sul1, aph(3")-Ib, aph(6)-Id, tet(A), tet(B), aadA1, aph(3′)-Ia, blaTEM-1, floR, dfrA1, dfrA8, aac(3)-IId, aadA2, aadA22, blaCARB-2, blaCMY-2, blaCTX-M-1/15/27/55, blaHER-3, blaLAP-2, ampC C11T, fosA7.5, lnu(F), catA1, gyrA S83L, qnrA1/S1, sul3, dfrA7/8/12/14/51, arr-2, erm(B), aph(3′)-IIa, aph (6)-Ic, blaCMY-2, blaCTX-M-14/27, blaHER-3, ble, mef(C), mph(ABG), gyrA D87Y/S83L, qnrB19/S1, dfrA51, and erm(F).
Antibiotic susceptibility pattern and resistance genes in Salmonella strains isolated from cattle.
The study identified tetracycline resistance genes tetA and tetC, and the beta-lactamase gene blaTEM-1 in Salmonella isolates from cattle, highlighting the prevalence of multidrug resistance.
Multidrug-resistant Klebsiella pneumoniae and Klebsiella oxytoca isolated from backyard broiler chickens and their contacts with antimicrobial resistance genes of Klebsiella pneumoniae.
The study identified multiple antimicrobial resistance genes in Klebsiella pneumoniae and Klebsiella oxytoca isolates from backyard broiler chickens and human contacts, including ermB, blaTEM, blaCTX-M1, sul1, tetA, gyrA, blaOXA-48, and mcr-1, indicating widespread multidrug resistance.
Susceptibility of a peri-urban water supply and sanitation system to selected emerging micropollutants.
The study identified the presence of antibiotic resistance genes (ARGs) in most samples, including tetA, blaTEM, and intl1, which were detected in raw and treated sewage, as well as in river water after sewage discharge. These genes were found to confer resistance to tetracycline, beta-lactam, and multidrug, respectively.
City or Suburb, Resistance Flows: Wastewater-Borne ESKAPE and AMR Genes in Malaysian Hospitals.
The study identified several AMR genes, including ermB, VanA, BlaTEM, tetA, Sul1, and BlaNDM-1, in ESKAPE pathogens from hospital wastewater in Klang Valley and suburban areas of Malaysia. These genes were associated with resistance to various antibiotics, highlighting the significance of hospital wastewater as a reservoir for AMR genes.
Characterisation of Plasmid-Associated Antimicrobial Resistance Genes in Coastal Marine Enterobacterales from the Central Adriatic Sea: De Novo Assembly and Bioinformatic Profiling.
The study identified nine clinically relevant antimicrobial resistance genes (ARGs) in plasmid-like assemblies from marine Enterobacterales, including blaKPC, blaTEM, aacA4, folP, and tetA, highlighting the potential for horizontal gene transfer in coastal environments.
Comprehensive analysis of Escherichia coli in bovine urinary tract infections: serotypes, antibiotic resistance, and virulence gene profiles.
The study identified multiple antimicrobial resistance genes in E. coli isolates from bovine urinary tract infections, including tetA, gyrA, blaSHV, floR, and aac(3)-IV, highlighting the prevalence of multidrug resistance.
Antibiotic susceptibility patterns of clinical isolates of salmonella species producing extended spectrum beta lactamases as predictor of multidrug resistance in a tertiary hospital, Southeastern Nigeria.
The study identified blaTEM, tetA, and sul1 as the most prevalent resistance genes in Salmonella isolates, which are associated with multidrug resistance and extended-spectrum beta-lactamase production.
Genomic analysis of multidrug-resistant Salmonellaenterica Serovar Montevideo isolates in China.
The study identified multiple AMR genes in Chinese S. Montevideo isolates, including beta-lactamases (bla TEM−1B, bla OXA−1, bla LAP−2, bla CTX−M−55, bla CTX−M−65, bla DHA−1), quinolone resistance genes (qnrS2, qnrS1, qnrA1, qnrB6, qnrB4, qepA1), macrolide resistance genes (mphA, mphE, msrE, mphB), tetracycline resistance genes (tetA, tetD, tetB), sulfonamide resistance genes (sul1, sul2, dfrA14, dfrA12, dfrA27, sul3), and chloramphenicol resistance genes (floR, catA2, catB3).
Roles of micro/nanoplastics in the spread of antimicrobial resistance through conjugative gene transfer.
The study shows that micro/nanoplastics (M/NPs) enhance the conjugative transfer of antibiotic resistance genes (ARGs) between bacteria, particularly in systems involving Escherichia coli and Enterococcus faecalis. The 20-nm and 1-μm PS M/NPs significantly facilitated ARG transfer, with the latter showing a stronger effect on E. coli recipients. The mechanism involves increased reactive oxygen species (ROS) production, altered cell membrane permeability, and changes in gene expression related to conjugation.
Slaughterhouse Wastewater as a Reservoir of Thermotolerant E. coli With Antimicrobial Resistance and Virulence Potential in Dhaka, Bangladesh.
The study identified several AMR genes in E. coli isolates from slaughterhouse wastewater, including blaTEM, blaCTX-M-15, blaIMP-1, blaIMP-4, blaOXA-48, dfrA17, tetA, sul2, and qnrS, highlighting the presence of multidrug-resistant strains.
Genetic Basis of Multiple Antibiotic Resistance of Pathogenic Escherichia coli Strains Isolated from Livestock Complexes in Krasnodar Krai, Russia.
The study identified multiple antibiotic resistance genes in E. coli strains isolated from livestock in Russia, including β-lactamases, efflux pumps, and tetracycline resistance genes, contributing to multidrug resistance.
Cloning and characterization of a tetracycline resistance determinant present in Agrobacterium tumefaciens C58.
The study identifies and characterizes the tetracycline resistance genes tetA and tetR from Agrobacterium tumefaciens C58, which confer resistance to tetracycline through an efflux mechanism.
No comments yet. Be the first to comment!