Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
tetracycline efflux ABC transporter TetAB subunit B
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| H121R | - | - | E. coli, Salmonella spp, Shigella spp | tetracycline | Reslit | Candidate |
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| tetB | Reference Gene CatalogReslit | 249 | TETRACYCLINE, tetracycline +4 | Corynebacterium striatum +128 | Japan, India|Mexico|Egypt|Morocco|Peru|Kenya|Senegal|Mali|South Africa|Vietnam|Nepal|Indonesia|Bolivia|Equatorial Guinea|Uganda|Cameroon|Guatemala|Philippines|Burkina-Faso, Jamaica, United States, Canada, Mozambique, California, Lake Michigan, Germany, United States|Switzerland|Czech Republic|New Zealand, Spain, Iran, India, Poland, Gabon, Okinawa Prefecture, Japan, Nepal, Tunisia, Ecuador, poultry, Eastern Cape, South Africa, Malaysia, Taiwan, UK|Cyprus, Nigeria, Europe|Portugal, San Francisco|Seattle|Minnesota|Minneapolis|Sacramento|Dallas|Jackson, South Korea, West Bengal, Southern Alberta, Canada, China, Rio de Janeiro, Brazil, Chile, Tanzania|Thailand|human|swine, Jordan, UK, Southeastern Brazil, Northern Thailand, South Africa, Alberta, Canada, USA, Southern China, Maputo, Mozambique, Netherlands, United Kingdom, Tai'an, China, Italy|Far East countries, Europe|Southern and Western Ireland, Lake Victoria, Tanzania, Bangladesh, northern Xinjiang, China|China, Brazil, Black Sea, United States|Tanzania, Thailand, Eastern Cape Province, South Africa, West Cameroon, Brazilian Amazon, Korea, Eastern Cape Province, Republic of South Africa|South Africa, Europe, Balochistan, Kenya, North America|Asia|Europe|Australia|South America, Portugal|Porto, Sweden, Slovakia, sub-Saharan Africa|Burkina Faso|Ghana|Guinea-Bissau|Kenya|Senegal, Europe|China|Egypt|Vietnam|Colombia, Turkey, Egypt, Northeastern Ohio, the United States|Northeastern Ohio, Northeast Tunisia, Europe|Asia, Europe|Italy, Tanzania, Senegal, Romania|France, Europe|North America|Netherlands|Denmark|Pennsylvania|United States|France, Kuwait, Mexico, Vietnam, Georgia, USA|Georgia, Guizhou Province, China, Indonesia, North America|Asia|Europe|Middle East|Africa, Southern Brazil, Europe|USA|Portugal|Germany|Australia|China|India|Pakistan|Sweden|Colorado, Nepal|Kathmandu, Nepal, South Africa|Europe, Abuja, Nigeria, Democratic Republic of Congo|Democratic Republic of the Congo, Romania|Cluj County, North Western Romania, Jaén, Spain|Jaén, Iraq, Algeria, Italy, Zagreb, Croatia|Zagreb|Croatia, Pakistan, Uruguay, Anhui, China, Northern Kazakhstan, Western Africa|Mali, Taiyuan City, Shanxi Province, China, Sicily, South America, Australia, North Carolina, Peruvian Amazon, Brazil|Europe|United Kingdom|United States, Bangkok, Thailand, Hebei Province|China|Hebei Province, China, Fiji, Ghana, Anhui province, China, Europe|Russia, Portugal|various regions, Fujian Province, Southeast China|China, Somali region, Ethiopia|Somali Region, Ethiopia, East China, Europe|Africa|North America|South America|Asia|Oceania, Kentucky|USA, Abakaliki, Nigeria, Qatar, Northern Italy, Kano, Nigeria|Nigeria, Western Balkans|Hungary, Paraguay, Inner Mongolia|Inner Mongolia, China, Wuhan, South China | 1999, 2003, 2004, 2006, 2008, 2009, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025, 2026 | U21300.1 | AAC95480.1 |
| tet B | Reslit | 22 | tetracycline, doxycycline | Salmonella enterica +17 | South Africa|Brazil, Yangzhou City, India, northern Xinjiang, China|China, South Africa, Western Cape, South Africa, Egypt, West Bengal, India, Edo State, Nigeria, Bangladesh, north-central Nigeria, Italy, Upper Oconee Watershed, Athens, GA, USA|Upper Oconee Watershed, Georgia, USA, Portugal|various regions, Europe, Iran, Shandong, China, India|Delhi NCR, India|China|Brazil | 2016, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025 | KX981212|KX981438|KY048431|KY048441 | - |
The tetAB genes of the Corynebacterium striatum R-plasmid pTP10 encode an ABC transporter and confer tetracycline, oxytetracycline and oxacillin resistance in Corynebacterium glutamicum.
Similarity of tetracycline resistance genes isolated from fish farm bacteria to those from clinical isolates.
The study identified tetracycline resistance genes (tetB, tetC, tetD, tetY, and tetG) in fish farm bacteria that are similar to those found in clinical isolates, indicating a shared origin of these resistance genes.
Mechanism of resistance to several antimicrobial agents in Salmonella Clinical isolates causing traveler's diarrhea.
The study identified several AMR genes and mutations in Salmonella isolates causing traveler's diarrhea, including blaTEM, blaOXA-1, tetA, tetB, tetG, dfrA1, dfrA12, dfrA14, dfrA17, floR, cmlA, and a mutation in the gyrA gene. These genes and mutations contribute to resistance against ampicillin, tetracycline, trimethoprim, chloramphenicol, and quinolones.
Mechanisms of resistance in multiple-antibiotic-resistant Escherichia coli strains of human, animal, and food origins.
Antimicrobial resistance of Escherichia coli isolates from broiler chickens and humans.
The study identified tetracycline resistance in E. coli isolates from broiler chickens and humans, primarily mediated by the efflux genes tetB and tetD.
Biochemical and molecular characterization of tetracycline-resistant Aeromonas veronii isolates from catfish.
The study identified tetE as the predominant tetracycline resistance gene in Aeromonas veronii isolates from catfish, followed by tetB, tetA, tetC, and tetD.
Genetic characterization of clinical and agri-food isolates of multi drug resistant Salmonella enterica serovar Heidelberg from Canada.
The study identified the bla_cmy-2 gene as a major contributor to extended-spectrum cephalosporin resistance in Salmonella enterica serovar Heidelberg isolates, with the gene also found in E. coli isolates. The gene was located on high-molecular-weight plasmids and contributed to multidrug resistance.
Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique.
The study identified multiple AMR genes in Shigella and Salmonella isolates, including bla-oxa-1-like, bla-tem-like, dfrA1, dfrA14-like, tetB, tetA, floR, cmlA, and cat, which confer resistance to ampicillin, trimethoprim-sulfamethoxazole, tetracycline, and chloramphenicol.
Antimicrobial resistance genes in Escherichia coli isolates recovered from a commercial beef processing plant
The study identified various antimicrobial resistance genes in E. coli isolates from a commercial beef processing plant, including beta-lactamase genes (blaCMY, blaSHV, blaTEM), tetracycline resistance genes (tetA, tetB, tetC), sulfonamide resistance genes (sul1, sul2), and aminoglycoside resistance genes (strA, strB).
Longitudinal characterization of resistant Escherichia coli in fecal deposits from cattle fed subtherapeutic levels of antimicrobials.
The study identified several AMR genes, including blaTEM1, tetA, tetB, tetC, sul1, and sul2, in Escherichia coli from cattle fecal deposits. These genes conferred resistance to ampicillin, tetracycline, and sulfonamides.
A unified approach to molecular epidemiology investigations: tools and patterns in California as a case study for endemic shigellosis.
The study identified the presence of tetB, catA, and blaTEM genes in Shigella isolates, which confer resistance to tetracycline, chloramphenicol, and ampicillin, respectively. These genes were detected through PCR analysis in a significant proportion of the isolates.
Efflux-mediated antibiotic resistance in Acinetobacter spp.
The study characterizes several efflux pumps in Acinetobacter spp., including AdeABC, AdeIJK, AdeFGH, CraA, AmvA, AbeM, AbeS, AdeXYZ, AdeDE, TetA, TetB, CmlA, FloR, and QacE, which contribute to multidrug resistance by expelling antibiotics and other compounds.
Influence of tetracycline resistance on the transport of manure-derived Escherichia coli in saturated porous media.
The study identified the presence of the tetB gene in tetracycline-resistant E. coli strains, which is associated with tetracycline efflux and contributes to increased mobility of these strains in saturated porous media.
Comparison of the Transport of Tetracycline-Resistant and Tetracycline-Susceptible Escherichia coli Isolated from Lake Michigan.
The study identified the tetB gene as responsible for tetracycline resistance in E. coli strains isolated from Lake Michigan, demonstrating that tetracycline-resistant strains exhibit higher mobility in saturated porous media compared to susceptible strains.
Detection and sequencing of plasmid encoded tetracycline resistance determinants (tetA and tetB) from food-borne Bacillus cereus isolates.
The study identified the presence of tetA and tetB genes in food-borne Bacillus cereus isolates, indicating plasmid-mediated tetracycline resistance and potential horizontal gene transfer.
Development and Evaluation of a Microarray-Based Serogenotyping Assay for Salmonella
The study presents a microarray-based serogenotyping assay for Salmonella, demonstrating high correlation between genotypic and phenotypic characteristics. Several AMR genes were identified and validated, showing strong association with AMR phenotypes.
Long-term exposure to antibiotics has caused accumulation of resistance determinants in the gut microbiota of honeybees.
The study identifies eight tetracycline resistance genes (tetB, tetC, tetD, tetH, tetL, tetY, tetM, and tetW) in the gut microbiota of honeybees, highlighting the accumulation of resistance determinants due to long-term antibiotic exposure in beekeeping practices.
DNA microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii clinical isolates.
The study developed a DNA microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii clinical isolates, identifying numerous resistance genes and mutations associated with carbapenem, aminoglycoside, fluoroquinolone, and other antibiotic resistances.
Contribution of efflux pumps, porins, and β-lactamases to multidrug resistance in clinical isolates of Acinetobacter baumannii.
The study identifies multiple efflux pumps, porins, and β-lactamases contributing to multidrug resistance in Acinetobacter baumannii, including adeB, adeJ, tetB, tetA(39), and aacC1, aphA1, aadB genes, along with mutations in gyrA and parC.
Characterization of multi-antibiotic-resistant Escherichia coli Isolated from beef cattle in Japan.
The study identified multiple AMR genes in E. coli isolates from beef cattle in Japan, highlighting the diversity of resistance mechanisms and the potential for horizontal gene transfer.
Characterization of Escherichia coli virulence genes, pathotypes and antibiotic resistance properties in diarrheic calves in Iran.
The study identified several antibiotic resistance genes in E. coli isolates from diarrheic calves in Iran, including aadA1, sul1, aac[3]-IV, dfrA1, tetA, and tetB, which confer resistance to streptomycin, sulfonamide, gentamicin, trimethoprim, and tetracycline.
Evaluation of Ciprofloxacin (gyrA, parC Genes) and Tetracycline (tetB Gene) Resistance in Nosocomial Acinetobacter baumannii Infections.
The study identified gyrA and parC gene mutations contributing to ciprofloxacin resistance and tetB gene presence linked to tetracycline resistance in A. baumannii isolates.
Phylogenetic distribution and prevalence of genes encoding class I Integrons and CTX-M-15 extended-spectrum β-lactamases in Escherichia coli isolates from healthy humans in Chandigarh, India.
The study identifies the presence of class 1 integrons and bla CTX-M-15 genes in commensal E. coli isolates from healthy individuals in Chandigarh, India. It also detects several gene cassettes conferring resistance to trimethoprim, streptomycin, spectinomycin, streptothricin, chloramphenicol, tetracycline, and sulfonamides.
Diversity, distribution and quantification of antibiotic resistance genes in goat and lamb slaughterhouse surfaces and meat products.
The study identified various tetracycline, sulfonamide, and beta-lactam resistance genes in goat and lamb slaughterhouse surfaces and meat products, highlighting the prevalence of tet genes and their potential role in the spread of antibiotic resistance.
Prevalence of virulence determinants and antimicrobial resistance among commensal Escherichia coli derived from dairy and beef cattle.
The study identified several antimicrobial resistance genes in commensal E. coli from dairy and beef cattle, including blaTEM, blaSHV, aadA1, tetA, tetB, and tetC. These genes conferred resistance to ampicillin, streptomycin, and tetracycline. Dairy cattle isolates showed higher resistance rates compared to beef cattle.
Isolation of multiple drug-resistant enteric bacteria from feces of wild Western Lowland Gorilla (Gorilla gorilla gorilla) in Gabon.
The study identified two multiple drug-resistant strains, GG6-2 and GG6-1-1, from feces of wild Western Lowland Gorillas in Gabon. Strain GG6-1-1 was found to carry the tetB gene, which confers resistance to tetracycline.
Resistance phenotypes and genotypes among multiple-antimicrobial-resistant Salmonella enterica subspecies enterica serovar Choleraesuis strains isolated between 2008 and 2012 from slaughter pigs in Okinawa Prefecture, Japan.
The study identified multiple antimicrobial resistance genes in Salmonella enterica subspecies enterica serovar Choleraesuis strains, including blaTEM, strA, strB, aadA1, aadA2, aphA1, aacC2, tetB, sul1, sul2, dhfrXII, and dhfrXIII. Additionally, mutations in the QRDRs of gyrA and parC were associated with quinolone resistance.
Clinical epidemiology and molecular analysis of extended-spectrum-β-lactamase-producing Escherichia coli in Nepal: characteristics of sequence types 131 and 648.
The study identified bla CTX-M-15, aac (3)-IIa, aadA1, aadA2, aadA5, qnrB4, qnrS1, aac (6')-Ib-cr, bla OXA-1, bla TEM-1B, bla SHV-12, bla CMY-42, bla DHA-1, mphA, ermB, catA1, catB3, sul1, sul2, dfrA12, dfrA17, dfrA1, dfrA5, tetA, tetB, and tetD as key AMR genes in ESBL-producing E. coli isolates in Nepal, highlighting the prevalence of multidrug resistance.
Occurrence of bla CTX-M-1, qnrB1 and virulence genes in avian ESBL-producing Escherichia coli isolates from Tunisia.
The study identified blaCTX-M-1, qnrB1, tetA, tetB, sul1, sul2, and sul3 genes in avian ESBL-producing E. coli isolates from Tunisia, highlighting their role in resistance to beta-lactams, quinolones, and sulfonamides.
Effects of selection pressure and genetic association on the relationship between antibiotic resistance and virulence in Escherichia coli.
The study identifies tetA, tetB, intl1, and qnrB as genes associated with antibiotic resistance in Escherichia coli, highlighting their roles in tetracycline, sulfamethoxazole-trimethoprim, and quinolone resistance.
Draft Genome Sequence of a Pathogenic O86:H25 Sequence Type 57 Escherichia coli Strain Isolated from Poultry and Carrying 12 Acquired Antibiotic Resistance Genes.
The study reports the draft genome sequence of an E. coli strain carrying 12 acquired antibiotic resistance genes, including beta-lactamases, aminoglycoside modifying enzymes, sulfonamide resistance, trimethoprim resistance, tetracycline resistance, and streptothricin resistance.
Identification and antimicrobial resistance prevalence of pathogenic Escherichia coli strains from treated wastewater effluents in Eastern Cape, South Africa.
The study identified several AMR genes in E. coli isolates from wastewater effluents, including strA, aadA, catI, cmlA1, blaTEM, and various tetracycline resistance genes (tetA, tetB, tetC, tetD, tetK, tetM). These genes conferred resistance to multiple antibiotics such as streptomycin, gentamicin, chloramphenicol, ampicillin, and tetracycline.
Comparative Genomics of Two ST 195 Carbapenem-Resistant Acinetobacter baumannii with Different Susceptibility to Polymyxin Revealed Underlying Resistance Mechanism.
The study identified blaOXA-23 and blaAmpC genes contributing to carbapenem and extended-spectrum cephalosporin resistance, and mutations in pmrA, pmrB, lpxD, lpxC, and lpsB genes linked to polymyxin resistance in A. baumannii AC30.
In Vivo and In Vitro Efficacy of Minocycline-Based Combination Therapy for Minocycline-Resistant Acinetobacter baumannii.
The study identified the tetB gene as a key determinant of minocycline resistance in Acinetobacter baumannii isolates, and demonstrated that combination therapy with colistin was more effective against minocycline-resistant isolates compared to other combinations.
Prevalence of virulence and antimicrobial resistance genes in Salmonella spp. isolated from commercial chickens and human clinical isolates from South Africa and Brazil.
The study identified the presence of virulence and antimicrobial resistance genes in Salmonella isolates from commercial chickens and human clinical samples in South Africa and Brazil. Key resistance genes included pse-1 (ampicillin), ant (3")-la (gentamicin), tet A and tet B (tetracycline), and sul 1 and sul 2 (sulfamethoxazole).
ICEApl1, an Integrative Conjugative Element Related to ICEHin1056, Identified in the Pig Pathogen Actinobacillus pleuropneumoniae.
The study identifies ICEApl1, an integrative conjugative element in Actinobacillus pleuropneumoniae, which contains tetracycline resistance genes tetB, tetC, tetD, and tetR. This element confers tetracycline resistance and was found in serovar 8 isolates.
Whole-Genome Sequencing for Detecting Antimicrobial Resistance in Nontyphoidal Salmonella.
The study identified 65 unique resistance genes in nontyphoidal Salmonella, including bla CTX-M1 and bla SHV2a, which were first reported in retail meat isolates in the United States. The research highlights the effectiveness of whole-genome sequencing in detecting antimicrobial resistance genes and correlating them with phenotypic resistance.
Carbapenem Resistance in Clonally Distinct Clinical Strains of Vibrio fluvialis Isolated from Diarrheal Samples.
The study identifies the bla NDM-1 gene as a major cause of carbapenem resistance in Vibrio fluvialis isolates from Kolkata, India. Several additional resistance genes, including aadA1, aadB, aac(6')-Ib-cr, sul1, sul3, floR, bla OXA-1, bla OXA-7, bla OXA-9, bla TEM-9, bla CTX-M-3, strA, and tetB, were also characterized.
Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa.
The study identified multiple S. Typhi genotypes in Nigeria, with a focus on antimicrobial resistance genes and plasmids. Key resistance genes included blaTEM-1, catA1, tetB, dfrA15, sul1, sul2, strAB, aad, and qnrS, primarily associated with the IncHI1 plasmid. Quinolone resistance was linked to gyrA mutations S83Y and S83F.
Architecture of Class 1, 2, and 3 Integrons from Gram Negative Bacteria Recovered among Fruits and Vegetables.
The study identified several AMR genes in Gram-negative bacteria from fresh produce, including mcr-1, qnrA1, blaGES-11, mphA, and oqxAB, highlighting the presence of mobile genetic elements and clinically relevant resistance genes.
Effects of Menthol Supplementation in Feedlot Cattle Diets on the Fecal Prevalence of Antimicrobial-Resistant Escherichia coli.
The study found that menthol supplementation in feedlot cattle diets increased the prevalence of tetracycline-resistant E. coli isolates. Specifically, 56.9% of isolates from the menthol group were resistant to tetracycline compared to 32.7% in the control group. The study also identified the presence of tetA and tetB genes in the resistant isolates.
Determination of antibiotic resistance genes in relation to phylogenetic background in Escherichia coli isolates from fecal samples of healthy pet cats in Kerman city.
The study identified several antibiotic resistance genes in E. coli isolates from healthy pet cats, including tetB, tetA, aadA, sulI, qnrS, and dhfrV, with varying prevalence rates. These genes were associated with resistance to tetracycline, aminoglycosides, sulfonamides, fluoroquinolones, and trimethoprim.
Genomic Analysis of Factors Associated with Low Prevalence of Antibiotic Resistance in Extraintestinal Pathogenic Escherichia coli Sequence Type 95 Strains.
The study identifies several AMR genes in ST95 E. coli strains, including blaTEM-1, blaCTX-M14, aadA1, aadA2, aadA5, aac3, strA, strB, tetA, tetB, tetD, sul1, sul2, dfrA5, dfrA12, dfrA17, mphA, and catA1, which confer resistance to various antibiotics such as ampicillin, cephalothin, streptomycin, tetracycline, sulfamethoxazole, trimethoprim, azithromycin, and chloramphenicol.
Prevalence, virulence potential, and pulsed-field gel electrophoresis profiling of Shiga toxin-producing Escherichia coli strains from cattle.
The study identified various antimicrobial resistance genes in STEC isolates from cattle, including ampC, blaTEM, tetE, tetB, and tetC, which confer resistance to beta-lactams and tetracyclines. These findings highlight the importance of monitoring antimicrobial resistance in STEC strains.
Detection of emerging antibiotic resistance in bacteria isolated from subclinical mastitis in cattle in West Bengal.
The study identified blaCTX-M, blaTEM, tetA, and tetB genes in Gram-negative bacteria isolated from subclinical mastitis in cattle in West Bengal, indicating the presence of antibiotic resistance mechanisms.
Subtype-Specific Selection for Resistance to Fluoroquinolones but Not to Tetracyclines Is Evident in Campylobacter jejuni Isolates from Beef Cattle in Confined Feeding Operations in Southern Alberta, Canada.
The study identifies tetO as the primary tetracycline resistance gene in Campylobacter jejuni isolates from beef cattle and highlights gyrA mutations, particularly Thr86Ile, as a major cause of fluoroquinolone resistance.
High diversity and abundance of cultivable tetracycline-resistant bacteria in soil following pig manure application.
The study identifies several tetracycline resistance genes (tet B, tet L, tet Z, tet M, tet O, and tet X) in cultivable tetracycline-resistant bacteria from pig manure and soil, highlighting the diversity and abundance of these genes following pig manure application.
Characterization of antimicrobial resistance genes in Haemophilus parasuis isolated from pigs in China.
The study identified multiple antimicrobial resistance genes in Haemophilus parasuis isolates from pigs in China, including blaTEM-1, blaROB-1, ermB, ermA, flor, catl, tetB, tetC, rmtB, rmtD, aadA1, aac(3′)-IIc, sul1, and sul2. Additionally, mutations in the gyrA and parC genes were associated with fluoroquinolone resistance.
Investigation of Efflux-Mediated Tetracycline Resistance in Shigella Isolates Using the Inhibitor and Real Time Polymerase Chain Reaction Method.
The study identified tetA and tetB genes as contributors to tetracycline resistance in Shigella isolates, with tetA being prevalent in S. sonnei and tetB in S. flexneri. Efflux pump inhibitors like CCCP reduced MIC values, indicating the involvement of efflux mechanisms in resistance.
Genome sequence of a multidrug-resistant Corynebacterium striatum isolated from bloodstream infection from a nosocomial outbreak in Rio de Janeiro, Brazil.
The study reports the draft genome of a multidrug-resistant Corynebacterium striatum isolate, identifying several resistance genes including tetA, tetB, vanW, ermX, aph(3')-Ia, strA-strB, bla, and cmx, along with a mutation in the gyrA gene contributing to quinolone resistance.
Antibiotic resistance gene dynamics in the gut microbiota following amoxicillin-clavulanic acid treatment
The study identified several AMR genes, including aminoglycoside resistance genes (ksgA, strA, strB), beta-lactam resistance genes (blaCARB-4, blaCMY-1, blaCMY-2, blaCTX-M-1, blaCTX-M-12, blaDHA-1, blaOXA-1, blaSHV-1, blaSHV-37, blaSHV-3, blaTEM-1A, blaTEM-1B), and tetracycline resistance genes (tetA, tetB, tetC, tetK, tetL), that were enriched in the gut microbiota of healthy adults following amoxicillin-clavulanic acid treatment.
Extended antibiotic treatment in salmon farms select multiresistant gut bacteria with a high prevalence of antibiotic resistance genes.
The study identifies several AMR genes, including floR, fexA, and various tetracycline resistance genes (tetA, tetB, tetE, tetH, tetL, tetM, tet34, tet35), associated with resistance to florfenicol and oxytetracycline in gut bacteria from salmon farms. These genes were found in multiple bacterial species, highlighting the widespread nature of AMR in aquatic environments.
Characterisation of antibiotic resistance of Salmonella isolated from dog treats in Japan.
The study identified the presence of antibiotic-resistant Salmonella in dog treats in Japan, including the blaTEM gene, aadA1, aadA2, tetB, floR, catA1, dfrA12, and intI1 genes, indicating multidrug resistance.
Genotypic antimicrobial resistance assays for use on E. coli isolates and stool specimens.
The study developed and validated 85 PCR assays to detect 79 AMR genes and mutations associated with resistance across 10 antimicrobial classes, focusing on E. coli. The assays showed high concordance with sequencing and phenotypic susceptibility testing, demonstrating their potential for AMR surveillance in E. coli isolates and direct stool specimens.
Identification of Escherichia coli from broiler chickens in Jordan, their antimicrobial resistance, gene characterization and the associated risk factors.
The study identified several antimicrobial resistance genes in Escherichia coli isolates from broiler chickens in Jordan, including tetA, tetB, int1, sul1, sul2, blaTEM, and cat. These genes were associated with resistance to various antibiotics such as tetracycline, sulfonamides, beta-lactams, and chloramphenicol.
Diverse Commensal Escherichia coli Clones and Plasmids Disseminate Antimicrobial Resistance Genes in Domestic Animals and Children in a Semirural Community in Ecuador.
The study identified various antimicrobial resistance (AMR) genes in commensal Escherichia coli isolates from children and domestic animals in a semirural community in Ecuador. These genes included blaTEM-1B, dfrA8, qnrB19, strA, strB, tetA, tetB, sul1, sul2, and others, contributing to resistance against multiple antibiotics such as ampicillin, trimethoprim, tetracycline, and sulfamethoxazole. The research highlights the role of plasmids in disseminating these AMR genes and emphasizes the complexity of AMR transmission in such environments.
Antimicrobial resistance, virulence & plasmid profiles among clinical isolates of Shigella serogroups.
The study identified multiple antimicrobial resistance genes including bla OXA-1, bla TEM-1B, qnr S1, dfr A1, aad A1, sul II, tet B, and cat A1 in Shigella isolates. Additionally, novel mutations in gyr A, gyr B, par C, and par E genes were observed, contributing to quinolone resistance.
Determining antimicrobial susceptibility in Salmonella enterica serovar Typhimurium through whole genome sequencing: a comparison against multiple phenotypic susceptibility testing methods.
The study identified various AMR genes and mutations in Salmonella enterica serovar Typhimurium, including aadA, strAB, blaTEM, blaCARB, floR, cmlA1, catA1, qnrB19, sul1, sul2, sul3, dfrA1, dfrA12, dfrA14, tetA, tetB, tetC, tetG, and mutations in gyrA. These genes and mutations were validated through whole genome sequencing and phenotypic ASTs.
Dissemination of Multidrug-Resistant Commensal Escherichia coli in Feedlot Lambs in Southeastern Brazil.
The study identified multiple multidrug-resistant commensal E. coli isolates in feedlot lambs in Brazil, carrying various AMR genes including bla CTX-M-2, bla CTX-M-8, bla CTX-M-14, bla CTX-M-15, bla CMY-2, aac(3)-IIa, ant(2")-Ia, qnrB, tetA, tetB, sul1, sul2, floR, and cmlA. These genes confer resistance to beta-lactams, aminoglycosides, quinolones, tetracyclines, sulfonamides, and phenicols.
Multilocus sequence typing and bla (ESBL) characterization of extended-spectrum beta-lactamase-producing Escherichia coli isolated from healthy humans and swine in Northern Thailand.
The study identified bla CTX-M, bla TEM, and bla SHV as the primary ESBL genes in ESBL-producing E. coli isolates from healthy humans and swine in Northern Thailand. Additionally, several other AMR genes such as sul1, sul2, sul3, aadA22, aph(3')-Ia, strA, strB, aadA2, aadA5, qnrS1, tetA, tetB, tetD, arr2, and mefB were characterized.
Characterization of Non-O157 Escherichia coli from Cattle Faecal Samples in the North-West Province of South Africa.
The study identified several antimicrobial resistance genes in non-O157 E. coli isolates from cattle fecal samples, including tetA, tetB, blaTEM-1, aadA1, and catA1, which were associated with resistance to tetracycline, ampicillin, streptomycin, and chloramphenicol.
Comparative diversity of microbiomes and Resistomes in beef feedlots, downstream environments and urban sewage influent.
The study identified several tetracycline, macrolide, aminoglycoside, beta-lactam, sulfonamide, mercury, and biocide resistance genes in beef feedlots, catch basin water, soil, and urban sewage influent. Tetracycline resistance was predominant in beef production systems, while urban sewage influent showed a diverse resistome with resistance to multiple antimicrobial classes.
Longitudinal Shedding Patterns and Characterization of Antibiotic Resistant E. coli in Pastured Goats using a Cohort Study.
The study identified tetracycline resistance mediated by tetB, ampicillin resistance via blaTEM, and streptomycin resistance through aadA and strpA/strpB genes in E. coli isolates from pastured goats. Mutations in gyrA conferred resistance to nalidixic acid.
Horizontal gene transfer contributes to virulence and antibiotic resistance of Vibrio harveyi 345 based on complete genome sequence analysis.
The study identified 25 antibiotic resistance genes in Vibrio harveyi 345, including genes for tetracycline (tetm, tetb), fluoroquinolone (qnrs), trimethoprim (dfra17), sulfonamide (sul2), and others, highlighting the role of horizontal gene transfer in its multidrug resistance.
Study of genetic diversity, biofilm formation, and detection of Carbapenemase, MBL, ESBL, and tetracycline resistance genes in multidrug-resistant Acinetobacter baumannii isolated from burn wound infections in Iran.
The study identified several AMR genes in multidrug-resistant Acinetobacter baumannii isolates, including bla OXA-23-like, bla OXA-40-like, bla OXA-51-like, bla VIM, bla PER-1, bla VEB-1, and tetB, which contribute to resistance against carbapenems, beta-lactams, and tetracyclines.
Gut carriage of antimicrobial resistance genes among young children in urban Maputo, Mozambique: Associations with enteric pathogen carriage and environmental risk factors.
The study identified several antimicrobial resistance genes (ARGs) in the gut of young children in urban Maputo, Mozambique, including aadA1, SHV, ermA, ermB, mefA, tetA, tetB, and others, which confer resistance to various antibiotics such as aminoglycosides, beta-lactams, macrolides, tetracyclines, and fluoroquinolones.
Effects of a Four-Week High-Dosage Zinc Oxide Supplemented Diet on Commensal Escherichia coli of Weaned Pigs.
The study identifies several antibiotic resistance genes (ARGs) and zinc tolerance genes in commensal Escherichia coli from weaned pigs, highlighting the impact of high-dose zinc oxide diets on selecting for resistant strains.
Impact of commonly used drugs on the composition and metabolic function of the gut microbiota.
The study identifies several AMR genes, including tetA, tetB, Mel, TolC, and mdtP, which are associated with resistance to tetracyclines and macrolides, and are influenced by drug use in the gut microbiota.
Resistance to change: AMR gene dynamics on a commercial pig farm with high antimicrobial usage.
The study identified multiple AMR genes, including tetB, tetQ, ermA, ermB, and dfrA1, which were associated with tetracycline, macrolide, and trimethoprim resistance in porcine fecal samples. These genes were found to be prevalent and diverse, with no significant changes in their abundance despite antimicrobial treatments.
Prevalence and characteristics of multidrug-resistant mcr-1-positive Escherichia coli isolates from broiler chickens in Tai'an, China.
The study identified mcr-1 as the primary cause of colistin resistance in E. coli isolates from broiler chickens in Tai'an, China, with high prevalence of multidrug resistance involving genes like bla TEM, bla CTX-M, aphA3, tetA, tetB, tetC, sul1, and sul2.
Complete Nucleotide Sequence of Plasmids of Two Escherichia coli Strains Carrying bla (NDM-) (5) and bla (NDM) (-) (5) and bla (OXA) (-) (181) From the Same Patient.
The study characterizes two carbapenemase-producing E. coli strains carrying blaNDM-5 and blaOXA-181, along with various other resistance genes such as qnrS1, blaCTX-M-15, aac(6')-lb-cr, catB3, sul1, dfrA17, qacEΔ1, aadA5, rmtB, ermB, mphA, tetB, catA1, dfrA14, dfrA12, blaTEM-1B, and blaCMY-42.
Functional metagenomics reveals antibiotic resistance determinants in dairy-associated microbial communities
The study identified several antibiotic resistance (AR) determinants in dairy products and processing environments, including genes conferring resistance to beta-lactams, tetracyclines, glycopeptides, macrolides, and streptogramins. Notably, Lactococcus lactis was found to be a significant reservoir of multidrug-resistant genes.
Population structure and antimicrobial resistance patterns of Salmonella Typhi isolates in urban Dhaka, Bangladesh from 2004 to 2016.
Genome-Based Analysis of Extended-Spectrum β-Lactamase-Producing Escherichia coli in the Aquatic Environment and Nile Perch (Lates niloticus) of Lake Victoria, Tanzania.
The study identified multiple AMR genes in ESBL-producing E. coli from Nile perch and water samples in Lake Victoria, including bla CTX-M-15, bla TEM-1B, aadA2, aac(3)-IId, sul1, sul2, dfrA12, qepA4, tetB, tetD, mphA, mdfA, catA1, strA, strB, nfaE, iss, vat, and lpfA.
Detection of antibiotic-resistant bacteria and their resistance genes from houseflies.
The study identified antibiotic-resistant bacteria from houseflies, including S. aureus, Salmonella spp., and E. coli, carrying resistance genes mecA, tetA, tetB, and mcr-3.
Antimicrobial resistance of Escherichia coli isolated from retail foods in northern Xinjiang, China.
The study identified various antimicrobial resistance genes in Escherichia coli isolates from retail foods in northern Xinjiang, China, including tetA, tetB, blaOXA, blaTEM, floR, sul1, sul2, aadAla, aadB, strA, and strB. These genes conferred resistance to tetracycline, beta-lactams, chloramphenicol, sulfonamides, and streptomycin.
Antimicrobial resistance of Escherichia coli isolated from retail foods in northern Xinjiang, China.
The study identified various antimicrobial resistance genes in Escherichia coli isolates from retail foods in northern Xinjiang, China, including tetA, tetB, blaOXA, blaTEM, floR, sul1, sul2, aadAla, aadB, strA, and strB. These genes conferred resistance to tetracycline, beta-lactams, chloramphenicol, sulfonamides, and streptomycin.
Extensively Drug-resistant Acinetobacter baumannii Belonging to International Clone II from A Pet Cat with Urinary Tract Infection; The First Report from Pakistan.
Co-occurrence of mcr-1, mcr-3, mcr-7 and clinically relevant antimicrobial resistance genes in environmental and fecal samples.
The study identified the co-occurrence of mcr-1, mcr-3, mcr-7.1, and various clinically relevant antimicrobial resistance genes in environmental and fecal samples from a Brazilian zoo, highlighting the potential reservoir of these genes in zoological environments.
Highly Transferable pAQU-Related Plasmids Encoding Multidrug Resistance Are Widespread in the Human and Fish Pathogen Photobacterium damselae subsp. damselae in Aquaculture Areas in the Black Sea.
The study identifies multiple multidrug resistance plasmids in Photobacterium damselae subsp. damselae, including novel versions of pAQU-group plasmids carrying resistance genes such as tetB, floR, sul2, qnrVC, dfrA, and strAB.
Prevalence and distribution of antimicrobial resistance determinants of Escherichia coli isolates obtained from meat in South Africa.
The study identified several AMR genes in E. coli isolates from meat in South Africa, including aadA, strA, aph(3)-Ia, aph(3)-IIa, aac(3)-IIa, blaTEM, blaZ, ampC, cat1, cat2, cmlA1, sul1, sul2, tetA, tetB, tetC, tetD, and tetM, which confer resistance to various antibiotics such as streptomycin, kanamycin, neomycin, gentamicin, amoxicillin, ampicillin, chloramphenicol, cotrimoxazole, and tetracycline.
High Level of Resistance to Antimicrobials and Heavy Metals in Multidrug-Resistant Pseudomonas sp. Isolated from Water Sources.
The study identified several AMR genes in multidrug-resistant Pseudomonas sp. isolates from water sources, including blaGES, qnrS, qepA, tetB, aac(3')-IIa, and ant(2'')-Ia, which confer resistance to various antibiotics.
Comparative analysis of multidrug resistance plasmids and genetic background of CTX-M-producing Escherichia coli recovered from captive wild animals.
The study identifies multiple AMR genes and mutations in MDR E. coli strains from captive wild animals, highlighting the presence of CTX-M-8 and CTX-M-65 beta-lactamases, along with various other resistance mechanisms such as aminoglycoside, tetracycline, and fluoroquinolone resistance genes, as well as mutations in quinolone resistance-determining regions.
Case Report: Successful Rescue Therapy of Extensively Drug-Resistant Acinetobacter baumannii Osteomyelitis With Cefiderocol.
The case report describes the successful use of cefiderocol in treating extensively drug-resistant Acinetobacter baumannii osteomyelitis, highlighting the identification of several resistance genes including blaOXA-23, blaOXA-66, armA, and tetB through whole-genome sequencing.
Antimicrobial Resistance, Virulence Genes, and Biofilm Formation Capacity Among Enterococcus species From Yaks in Aba Tibetan Autonomous Prefecture, China.
The study identified multiple antimicrobial resistance (AMR) genes in Enterococcus species isolated from yaks, including ermA, ermB, tetA, tetB, tetM, tetL, cat, optrA, and poxtA. These genes conferred resistance to various antibiotics such as erythromycin, tetracycline, chloramphenicol, and linezolid. Additionally, a high prevalence of multidrug-resistant (MDR) Enterococcus strains was observed.
Antimicrobial Resistance in Swine Fecal Specimens Across Different Farm Management Systems.
The study identified several AMR genes associated with different antimicrobial classes in swine fecal samples from farms with varying antimicrobial usage levels. These genes included beta-lactamases, aminoglycoside modifying enzymes, fluoroquinolone resistance genes, macrolide resistance markers, polymyxin resistance genes, phenicol resistance genes, and trimethoprim resistance genes.
Occurrence, Virulence and Antimicrobial Resistance-Associated Markers in Campylobacter Species Isolated from Retail Fresh Milk and Water Samples in Two District Municipalities in the Eastern Cape Province, South Africa.
The study identified several antimicrobial resistance genes in Campylobacter species isolated from retail fresh milk and water samples, including catII, tetA, tetB, tetM, ermB, gyrA, ampC, and aac(3)-IIa-(aacC2). These genes were associated with resistance to chloramphenicol, tetracycline, erythromycin, gentamicin, and ampicillin.
F Plasmids Are the Major Carriers of Antibiotic Resistance Genes in Human-Associated Commensal Escherichia coli.
The study identifies various antibiotic resistance genes in commensal E. coli isolates, highlighting the prevalence of resistance genes on F plasmids and the role of mobile genetic elements in their dissemination.
Profiling Virulence and Antimicrobial Resistance Markers of Enterovirulent Escherichia Coli from Fecal Isolates of Adult Patients with Enteric Infections in West Cameroon.
The study identified several AMR genes and mutations in enterovirulent E. coli isolates from adult patients in Cameroon, including blaTEM, blaOxa, cat1, cat2, tetB, tetA, tetG, sul2, and dfrA12, along with mutations in gyrA and parC contributing to quinolone resistance.
Genomic insights of Klebsiella pneumoniae isolated from a native Amazonian fish reveal wide resistome against heavy metals, disinfectants, and clinically relevant antibiotics.
The study identifies a multidrug-resistant Klebsiella pneumoniae strain carrying several AMR genes, including blaCTX-M-15, blaTEM-1B, blaSHV-27, aac(3)-IId, aadA1, sul2, tetB, tetD, fosA-like, oqxA, oqxB, and qnrE1, highlighting the potential of native Amazonian fish as reservoirs of clinically relevant AMR genes.
Lactobacillus spp. attenuate antibiotic-induced immune and microbiota dysregulation in honey bees.
The study identifies tetB as a tetracycline resistance gene that increases in abundance in the gut microbiota of honey bees following oxytetracycline treatment. Supplementation with Lactobacillus strains (LX3) mitigates antibiotic-associated microbiota dysbiosis and immune deficits.
Dynamic Changes in Antimicrobial Resistance in Fecal Escherichia coli from Neonatal Dairy Calves: An Individual Follow-Up Study.
The study identified the tetracycline resistance gene tetB as the most prevalent resistance gene in fecal E. coli from neonatal calves, highlighting its association with tetracycline resistance and potential transmission from maternal colostrum.
Genotypic antimicrobial resistance characterization of E. coli from dairy calves at high risk of respiratory disease administered enrofloxacin or tulathromycin.
The study identified several AMR genes and mutations in E. coli from dairy calves, including aac(6')Ib-cr, bla-CTX-M, bla-TEM, tetA, tetB, and gyrA mutations. These genes and mutations were associated with resistance to various antibiotics such as ciprofloxacin, ceftazidime, tetracycline, and others.
Complete genome analysis of a virulent Vibrio scophthalmi strain VSc190401 isolated from diseased marine fish half-smooth tongue sole, Cynoglossus semilaevis.
The study identified several AMR genes in Vibrio scophthalmi strain VSc190401, including those conferring resistance to aminoglycosides, fluoroquinolones, tetracyclines, and polymyxins. Some of these genes were validated experimentally.
Molecular Epidemiology of Antibiotic-Resistant Escherichia coli from Farm-To-Fork in Intensive Poultry Production in KwaZulu-Natal, South Africa.
The study identified the presence of bla CTX-M, sul1, tetA, and tetB genes in Escherichia coli isolates from various stages of the farm-to-fork continuum in intensive poultry production in South Africa.
Occurrence, identification, and antibiogram signatures of selected Enterobacteriaceae from Tsomo and Tyhume rivers in the Eastern Cape Province, Republic of South Africa.
The study identified various beta-lactamase genes (bla TEM, bla CTX-M, bla SHV, bla OXA-1-like, bla PER, bla VIM, bla IMP, bla KPC, bla GES, bla OXA-48-like), plasmid-mediated AmpC beta-lactamase genes (bla EBC, bla ACC, bla FOX, bla CIT), tetracycline resistance genes (tetA, tetB, tetD, tetM), chloramphenicol resistance gene (catII), and sulfonamide resistance gene (sulII) in Enterobacteriaceae isolates from Tsomo and Tyhume rivers.
In Vitro Activity of the Novel Tetracyclines, Tigecycline, Eravacycline, and Omadacycline, Against Moraxella catarrhalis.
The study identified tetB and tetL genes as tetracycline resistance genes in Moraxella catarrhalis. Mutations in the 16S rRNA genes (C1036T and/or G460A) were associated with omadacycline resistance.
Antibiotic Resistance and Virulence of Extraintestinal Pathogenic Escherichia coli (ExPEC) Vary According to Molecular Types.
The study identifies several antibiotic resistance genes (ARGs) and virulence factors (VFs) in extraintestinal pathogenic Escherichia coli (ExPEC) strains, highlighting their association with molecular types and resistance profiles.
Antimicrobial Resistance in Escherichia coli Strains Isolated from Humans and Pet Animals.
The study identifies several AMR genes in E. coli strains isolated from humans and pet animals, including blaTEM, qnrS1, qnrB1, blaCMY-2, blaCMY-59, tetA, tetB, sul1, sul2, and sul3, which confer resistance to various antibiotics such as beta-lactams, quinolones, tetracyclines, and sulfonamides.
Virulent and multidrug-resistant Klebsiella pneumoniae from clinical samples in Balochistan.
The study identifies multidrug-resistant Klebsiella pneumoniae isolates from clinical samples in Balochistan, highlighting the presence of tetracycline resistance gene tetB, sulfonamide resistance gene Sul1, and extended-spectrum beta-lactamase gene SHV. Additionally, virulence factors fimH1 and EntB were detected.
Higher prevalence of multidrug-resistant extended-spectrum β-lactamases producing Escherichia coli in unorganized pig farms compared to organized pig farms in Mizoram, India.
The study identified several AMR genes, including bla TEM, bla CTX-M, bla CMY, tetA, tetB, sul1, sul2, aadA, and dfrIa, in multidrug-resistant E. coli isolates from both organized and unorganized pig farms in Mizoram, India.
A Preliminary Study: Antibiotic Resistance of Escherichia coli and Staphylococcus aureus from the Meat and Feces of Various South African Wildlife Species.
The study identified antibiotic resistance genes in Escherichia coli and Staphylococcus aureus from wildlife meat and feces, including blaCMY, aadA, sul1, sul2, tetA, tetB, tetK, tetL, tetM, vanA, vanB, and blaZ, which conferred resistance to ampicillin, streptomycin, sulfonamides, tetracycline, vancomycin, and penicillin.
Effects of in ovo probiotic administration on the incidence of avian pathogenic Escherichia coli in broilers and an evaluation on its virulence and antimicrobial resistance properties.
The study identified various antimicrobial resistance genes in APEC isolates, including blaTEM, aac(3)-VIa, aac(3)-VIb, aadA, tetA, tetB, dfr7, qacEΔ, qnr, sul1, intl1, arsC, and merA. These genes conferred resistance to multiple antibiotics such as beta-lactams, aminoglycosides, tetracyclines, quinolones, sulfonamides, and heavy metals.
Endophytic Lifestyle of Global Clones of Extended-Spectrum β-Lactamase-Producing Priority Pathogens in Fresh Vegetables: a Trojan Horse Strategy Favoring Human Colonization?
The study identifies multiple AMR genes in endophytic ESBL-producing Enterobacterales isolated from fresh vegetables, highlighting their potential role in the spread of antibiotic resistance.
Clonal spread of multi-resistant Gallibacterium anatis isolates among Iranian broilers and layers.
The study identified the tetracycline resistance gene tetB in 16 out of 21 Iranian G. anatis strains, contributing to the multidrug resistance profile of these isolates.
Detection of diverse carbapenem and multidrug resistance genes and high-risk strain types among carbapenem non-susceptible clinical isolates of target gram-negative bacteria in Kenya.
The study identified various carbapenemase genes (blaNDM-1, blaNDM-5, blaVIM-1, blaVIM-6, blaOXA-23, blaOXA-58, blaOXA-66, blaOXA-69, blaOXA-91, blaOXA-181, blaOXA-50) and other resistance genes (such as armA, rmtC, rmtF, aac(3)-I, aadA1, aph(3')-Ia, aph(3')-VI, aph(3')-Via, aph(6')-Id, mphE, msrE, mphA, ereA, dfrA1, dfrA12, dfrA14, dfrA17, dfrA20, sul1, sul2, tetB, tetD, tetG, tet39, qnrVC1, qnrS1, qnrB4, floR, catA1, catA2, catB3, catB7, cmlA1, cmlA5, arr-3, arr-2, sat2, acrF, mdtM, emrD, mexA, mexE, mexX, kdeA, oxa-10, oxa-395, oxa-396, oxa-846, adc-25, dha-1, act-16, cmY, ctx-m-15, shv-67, tem-1b) in carbapenem non-susceptible clinical isolates of gram-negative bacteria in Kenya, highlighting the diversity and prevalence of multidrug resistance.
Genomic diversity and molecular epidemiology of Pasteurella multocida.
This study identified several antimicrobial resistance genes in Pasteurella multocida, including aminoglycoside, beta-lactam, tetracycline, macrolide, and sulfonamide resistance genes, highlighting the diverse resistance mechanisms present in this pathogen.
Comparative Characteristics and Zoonotic Potential of Avian Pathogenic Escherichia coli (APEC) Isolates from Chicken and Duck in South Korea.
The study identified several antimicrobial resistance genes in APEC isolates from chickens and ducks in South Korea, including mcr-1, blaTEM, blaCTX-M group I, blaCTX-M group IV, mphA, cat, floR, cmlA, strA-B, aadA, sul1, sul2, tetA, and tetB. These genes conferred resistance to various antibiotics such as colistin, ampicillin, azithromycin, chloramphenicol, streptomycin, sulfisoxazole, and tetracycline. The study also highlighted the zoonotic potential of certain APEC isolates, particularly those belonging to phylogenetic group B2.
Multidrug-resistant bacteria as intestinal colonizers and evolution of intestinal colonization in healthy university students in Portugal.
The study identified various AMR genes in commensal E. coli isolates from healthy university students in Portugal, including bla TEM, tetA, tetB, sul1, sul2, sul3, parC, and gyrA, indicating the presence of multidrug-resistant bacteria in the intestinal microbiota.
Molecular Characterization of Multidrug-Resistant Yersinia enterocolitica From Foodborne Outbreaks in Sweden.
The study identified a chromosomally encoded multidrug-resistance cassette carrying resistance genes against chloramphenicol (catA1), streptomycin (aadA1), sulfonamides (sul1), and a mercury resistance module, as well as a 5.7-kbp plasmid with tetB encoding an ABC transporter in Yersinia enterocolitica strains from a foodborne outbreak in Sweden.
Escherichia coli Antibiotic Resistance Patterns from Co-Grazing and Non-Co-Grazing Livestock and Wildlife Species from Two Farms in the Western Cape, South Africa.
The study identified several antibiotic resistance genes in E. coli isolates from livestock and wildlife, including bla CMY, aad A1, sul 1, sul 2, tet A, and tet B, which conferred resistance to ampicillin, streptomycin, sulfonamides, and tetracycline. The research highlights differences in resistance patterns between co-grazing and non-co-grazing animals.
Diversity of Plasmids and Genes Encoding Resistance to Extended-Spectrum β-Lactamase in Escherichia coli from Different Animal Sources.
The study identified various AMR genes and mutations in E. coli isolates from different animal sources, highlighting the presence of ESBL genes such as bla CTX-M-15, bla TEM-1B, and bla CMY-28, as well as mutations in parC and gyrA that confer resistance to fluoroquinolones.
Therapeutic Potential of Novel Mastoparan-Chitosan Nanoconstructs Against Clinical MDR Acinetobacter baumannii: In silico, in vitro and in vivo Studies.
The study identified the presence of antibiotic resistance genes gyrA, STrB, and TetB in clinical isolates of multidrug-resistant Acinetobacter baumannii, indicating resistance to ciprofloxacin, aminoglycosides, and tetracycline, respectively.
Antibiotic Resistant and Biofilm-Associated Escherichia coli Isolates from Diarrheic and Healthy Dogs.
The study identified several AMR genes in E. coli isolates from healthy and diarrheic dogs, including blaTEM-1, qnrB, qnrS, aac(6')-Ib-cr, tetA, tetB, dfrA, sul1, sul2, int1, and tn3. These genes confer resistance to various antibiotics such as ampicillin, ciprofloxacin, tetracycline, trimethoprim, and sulfonamide.
Transcriptomic Analysis of Drug-Resistance Acinetobacter baumannii under the Stress Condition Caused by Litsea cubeba L. Essential Oil via RNA Sequencing.
The study identifies several AMR genes in A. baumannii 17, including armA, sul2, tetB, and aac6'-1b, which confer resistance to beta-lactam, sulfonamide, tetracycline, and aminoglycoside antibiotics, respectively.
Detection of bla(TEM), bla(CTX-M), bla(CMY), and bla(SHV) Genes Among Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Isolated from Migratory Birds Travelling to Bangladesh.
The study identified bla(TEM), bla(CTX-M), bla(CMY), and bla(SHV) genes in extended-spectrum beta-lactamase-producing Escherichia coli isolated from migratory birds in Bangladesh, highlighting the role of migratory birds as potential carriers of antibiotic resistance genes.
Prevalence and mechanisms of antibiotic resistance in Escherichia coli isolated from mastitic dairy cattle in Canada.
The study identified several AMR genes in E. coli isolates from bovine mastitis, including beta-lactamases (blaTEM-1, blaCARB-3, blaCMY-59), tetracycline resistance genes (tetA, tetB, tetC), aminoglycoside resistance genes (aph(3')-Ia, aph(3'')-Ib, aph(6)-Id, aadA2), and multidrug efflux pump genes (acrA, acrB, acrD, tolC, baeR, emrA, emrB).
The genomic epidemiology of multi-drug resistant invasive non-typhoidal Salmonella in selected sub-Saharan African countries.
The study identified multiple AMR genes and mutations in invasive non-typhoidal Salmonella isolates from sub-Saharan Africa, highlighting the prevalence of multidrug resistance.
Genomic Epidemiology of Multidrug-Resistant Nontyphoidal Salmonella in Young Children Hospitalized for Gastroenteritis.
Phylum barrier and Escherichia coli intra-species phylogeny drive the acquisition of antibiotic-resistance genes.
The study analyzed 70,301 E. coli genomes and identified 1,027,651 antibiotic-resistance genes (ARGs). It found that certain ARGs were distributed according to the phylogenetic background of the strains, showing phenotypic adaptive convergence. The study also identified four instances of potential horizontal gene transfer of ARGs from non-Proteobacteria to E. coli.
Antimicrobial Resistance of Non-Typhoid Salmonella in Meat and Meat Products.
The study highlights the prevalence of antimicrobial resistance in non-typhoid Salmonella isolates from meat and meat products, emphasizing the resistance patterns to antibiotics such as tetracycline, sulfonamides, ampicillin, and streptomycin. It identifies Enteritidis and Typhimurium as the most common serovars with significant resistance levels.
Detection of mobile genetic elements in multidrug-resistant Klebsiella pneumoniae isolated from different infection sites in Hamadan, west of Iran.
The study identified the presence of sulI, sulII, tetA, tetB, intI, and intII genes in multidrug-resistant Klebsiella pneumoniae isolates, highlighting the role of these mobile genetic elements in the spread of antibiotic resistance.
Sequence Analyses and Phenotypic Characterization Revealed Multidrug Resistant Gene Insertions in the Genomic Region Encompassing Phase 2 Flagellin Encoding fljAB Genes in Monophasic Variant Salmonella enterica Serovar 4,5,12:i:- Isolates From Various Sources in Thailand.
The study identified multiple multidrug resistance genes, including blaTEM-1B, strA, strB, sul2, and tetB, in Salmonella enterica serovar 4,5,12:i:- isolates from Thailand, which contribute to resistance against ampicillin, streptomycin, sulfonamides, and tetracycline.
Molecular epidemiological analysis of integron gene cassettes and tetA/tetB/tetD gene associations in Escherichia coli strains producing extended-spectrum β-lactamase (ESBL) in urine cultures.
The study identified the tetB gene as the most prevalent tetracycline resistance gene in ESBL-producing E. coli isolates from urine cultures in Turkey.
Antimicrobial Susceptibility and Detection of Virulence-Associated Genes in Escherichia coli Strains Isolated from Commercial Broilers.
The study identified several AMR genes in E. coli strains from commercial broilers, including bla CTX-M-1 and bla CTX-M-2 for cephalosporin resistance, qnrA, qnrB, qnrS for fluoroquinolone resistance, aac(6')-Ib-cr for fluoroquinolone and aminoglycoside resistance, tetA and tetB for tetracycline resistance, sul1 and sul2 for sulfonamide resistance, aadA for aminoglycoside resistance, dfrA and dfrB for trimethoprim resistance, and mcr1 and mcr2 for polymyxin resistance.
Molecular characterization of Escherichia coli isolated from milk samples with regard to virulence factors and antibiotic resistance.
The study identified E. coli isolates from raw milk samples carrying virulence factors eae, hly, and stx2, along with antibiotic resistance genes blaTEM, tetA(A), and tetB, demonstrating multidrug resistance to several antibiotics.
Comparison of antimicrobial resistance and molecular characterization of Escherichia coli isolates from layer breeder farms in Korea.
The study identified several AMR genes in E. coli isolates from layer breeder farms in Korea, including bla TEM-1, tetA, tetB, qnrB, qnrS, sul1, sul2, aac(3)-II, and aac(6')-Ib. These genes conferred resistance to various antibiotics such as beta-lactams, tetracyclines, quinolones, sulfonamides, and aminoglycosides.
Prevalence and Antimicrobial Resistance Profiles of Foodborne Pathogens Isolated from Dairy Cattle and Poultry Manure Amended Farms in Northeastern Ohio, the United States.
The study identified several antimicrobial resistance genes in foodborne pathogens isolated from dairy cattle and poultry manure amended farms in Northeastern Ohio, including mphA, aadA, aphA1, tetA, aac(3)-IV, sulII, blaTEM, tetB, strA, aac(3)-Iva, ampC, lde, ermB, tet(O), aadB, penA, blaOXA-61, aadE, and aph-3-1.
Antimicrobial Resistance of Salmonella enteritidis and Salmonella typhimurium Isolated from Laying Hens, Table Eggs, and Humans with Respect to Antimicrobial Activity of Biosynthesized Silver Nanoparticles.
The study identified several AMR genes, including blaTEM, tetA, tetB, nfsA, and nfsB, in multidrug-resistant Salmonella enteritidis and Salmonella typhimurium isolates. These genes conferred resistance to ampicillin, tetracycline, and nitrofurantoin. Additionally, biosynthesized silver nanoparticles showed promising antimicrobial activity against these resistant strains.
Prevalence, Risk Factors, Antimicrobial Resistance and Molecular Characterization of Salmonella in Northeast Tunisia Broiler Flocks.
The study identified the bla CTX-M gene in extended-spectrum beta-lactamase (ESBL)-producing Salmonella strains, along with tetA, tetB, and dfrA1 genes in tetracycline and trimethoprim-resistant strains. High levels of multidrug resistance were observed.
Mobile Genetic Elements Drive Antimicrobial Resistance Gene Spread in Pasteurellaceae Species.
The study identifies 33 distinct AMR genes associated with mobile genetic elements (MGEs) in Pasteurellaceae species, highlighting the role of MGEs in the spread of antimicrobial resistance.
Anti-microbial resistance of Salmonella isolates from raw meat-based dog food in Japan.
The frequency of tetracycline resistance genes in Escherichia coli strains isolated from healthy and diarrheic pet birds.
The study identified tetA and tetB genes in E. coli isolates from pet birds, which are associated with tetracycline resistance through efflux pump mechanisms.
Whole genome sequencing-based classification of human-related Haemophilus species and detection of antimicrobial resistance genes.
The study identifies blaTEM-1D and tetB as resistance genes in Haemophilus isolates, correlating with ampicillin and tetracycline resistance, respectively.
Decreasing the abundance of tetracycline-resistant Escherichia coli in pig feces during nursery using flavophospholipol as a pig feed additive.
Flavophospholipol (FPL) effectively reduced the abundance of tetracycline-resistant Escherichia coli in pig feces by inhibiting conjugational transfer and growth of resistant plasmids carrying tetA, tetB, blaTEM-1B, mdfA, aph(3')-I, sul2, aadA1, and dfrA1.
Antimicrobial Resistance Dynamics in Chilean Shigella sonnei Strains Within Two Decades: Role of Shigella Resistance Locus Pathogenicity Island and Class 1 and Class 2 Integrons.
The study identifies multiple antimicrobial resistance genes in Chilean Shigella sonnei strains, including blaOXA-1, aadA1, cat, tetB, and dfrA14, which are associated with resistance to ampicillin, streptomycin, chloramphenicol, tetracycline, and trimethoprim, respectively. The SRL PAI and class 1 and 2 integrons play a significant role in the dissemination of multidrug-resistant strains.
Prevalence, Antimicrobial Resistance, and Whole Genome Sequencing Analysis of Shiga Toxin-Producing Escherichia coli (STEC) and Enteropathogenic Escherichia coli (EPEC) from Imported Foods in China during 2015-2021.
The study identified several antimicrobial resistance genes in STEC and EPEC isolates from imported foods in China, including blaTEM-1B, tetA, tetB, catA1, cmlA1, aadA1, aph(4)-Ia, aac(3)-IV, aph(6)-Id, aph(3")-Ib, sul3, dfrA12, and qnrS1, which conferred resistance to various antibiotics such as ampicillin, tetracycline, chloramphenicol, gentamicin, trimethoprim-sulfamethoxazole, and ciprofloxacin.
Overcoming Multidrug Resistance in Salmonella spp. Isolates Obtained From the Swine Food Chain by Using Essential Oils: An in vitro Study.
The study identified several AMR genes in Salmonella isolates from the swine food chain, including parC, catA1, nfsB, nfsA, blaTEM, tetA, and tetB, which confer resistance to various antibiotics such as gentamicin, amikacin, tobramycin, chloramphenicol, ampicillin, piperacillin, and tetracycline.
First identification of bla (NDM-5) producing Escherichia coli from neonates and a HIV infected adult in Tanzania.
The study identifies bla NDM-5 producing Escherichia coli in Tanzania, highlighting the presence of carbapenem resistance and other resistance genes on various plasmids.
Yersinia pestis antibiotic resistance: a systematic review.
Frequently used therapeutic antimicrobials and their resistance patterns on Staphylococcus aureus and Escherichia coli in mastitis affected lactating cows.
The study identified several antimicrobial resistance genes in Staphylococcus aureus and Escherichia coli isolated from mastitis-affected cows, including mecA, tetK, tetL, tetA, tetB, sul1, and sul2. These genes confer resistance to various antibiotics such as tetracycline, sulfamethoxazole-trimethoprim, and methicillin.
Virulence determinant and antimicrobial resistance traits of Emerging MDR Shiga toxigenic E. coli in diarrheic dogs.
The study identified several AMR genes in MDR Shiga toxigenic E. coli (STEC) isolated from diarrheic dogs in Egypt, including bla TEM, bla CTX-M, bla KPC, bla NDM-1, tet A, tet B, sul 1, and qnr A. These genes confer resistance to various antibiotics such as penicillins, cephalosporins, carbapenems, tetracyclines, sulfonamides, and quinolones.
Gut Commensal Escherichia coli, a High-Risk Reservoir of Transferable Plasmid-Mediated Antimicrobial Resistance Traits.
The study identified multiple plasmid-mediated antimicrobial resistance genes in gut commensal Escherichia coli isolates from healthy individuals, highlighting the potential risk of these bacteria as reservoirs of resistance traits.
Genomics of human and chicken Salmonella isolates in Senegal: Broilers as a source of antimicrobial resistance and potentially invasive nontyphoidal salmonellosis infections.
The study identified multiple antimicrobial resistance genes and mutations in Salmonella isolates from Senegal, highlighting the prevalence of resistance to fluoroquinolones, sulfamethoxazole-trimethoprim, tetracycline, and erythromycin. Key genes included aac(3)-Id, aadA7, blaTEM-1b, blaDHA-1, blaOXA-10, blaCMY-2, dfrA1, dfrA14, floR, fosA, qnrB19, qnrB7, sul2, tetA, tetB, aph(3')-Ib, aph(3")-Ib, and aph(6)-Id. Mutations in parC and gyrA were also associated with fluoroquinolone resistance.
Pathogenic E. coli from Cattle as a Reservoir of Resistance Genes to Various Groups of Antibiotics.
The study identified various AMR genes in pathogenic E. coli strains from cattle in Romania and France, highlighting the presence of multidrug-resistant (MDR) strains and the diversity of resistance mechanisms.
Invited Review: Antimicrobial Use and Antimicrobial Resistance in Pathogens Associated with Diarrhea and Pneumonia in Dairy Calves.
The review identified several AMR genes in pathogens associated with calf diarrhea and pneumonia, including beta-lactamases (blaCMY, blaCTX-M, blaTEM), tetracycline resistance genes (tetA, tetB, tetM, tetO), aminoglycoside resistance genes (strA, strB, aadA), sulfonamide resistance genes (sul1, sul2), phenicol resistance genes (cat, floR), and macrolide/lincosamide resistance genes (cfr, ermB).
Whole Genome Sequence Analysis of Multidrug Resistant Escherichia coli and Klebsiella pneumoniae Strains in Kuwait.
The study identified multiple AMR genes in multidrug-resistant E. coli and K. pneumoniae isolates from Kuwait, including beta-lactamases (blaKPC-2, blaCTX-M-15, blaOXA-1, blaCMY-4, blaTEM), aminoglycoside-modifying enzymes (aac(3)-IIa, aph(6)-Id, aadA5), sulfonamide resistance genes (sul1, sul2), quinolone resistance genes (gyrA_D87N, qnrB1), and others. Colistin resistance was linked to the pmrB_R256G mutation.
Molecular Epidemiology and Antimicrobial Resistance of Clostridioides difficile in Hospitalized Patients From Mexico.
The study identified several AMR genes and mutations in C. difficile isolates from Mexico, including cfrE, ermB, aadE, aadA27, aac(6')-Ie-aph(2'')-Ia, catP, blaCDD2, blaCCD1, tetM, tetO, tetB, tetA, and cdeA, along with mutations in rpoB, rpoC, fusA, and pbp2 associated with resistance to various antibiotics.
Analysis of Antimicrobial Resistance in Non-typhoidal Salmonella Collected From Pork Retail Outlets and Slaughterhouses in Vietnam Using Whole Genome Sequencing.
The study identified several AMR genes in non-typhoidal Salmonella isolates from pork retail outlets and slaughterhouses in Vietnam, including blaTEM-1, blaTEM-150, blaLAP-2, blaCTX-M-55, dfrA12, dfrA14, floR, cmlA1, tetA, tetB, tetM, mcr-1, mcr-3, qnrS1, mphA, aadA1, aadA2, aac(6')-laa, aac(6')-ly, sul1, sul2, sul3, aph(3")-lb, and aph6-ld. These genes conferred resistance to various antibiotics such as ampicillin, penicillins, first-generation cephalosporins, quinolones, trimethoprim, chloramphenicol, tetracycline, colistin, macrolides, gentamicin, sulfonamides, and others.
Analysis of Salmonella enterica Isolated from a Mixed-Use Watershed in Georgia, USA: Antimicrobial Resistance, Serotype Diversity, and Genetic Relatedness to Human Isolates.
The study identified multiple antimicrobial resistance genes in Salmonella enterica isolates from a mixed-use watershed in Georgia, USA, including bla CMY-2, aadA2, strA, strB, sul1, sul2, tetA, tetC, floR, and dfrA12, which conferred resistance to various antibiotics such as ceftiofur, ceftriaxone, streptomycin, sulfisoxazole, tetracycline, chloramphenicol, and trimethoprim.
Highly prevalent MDR, frequently carrying virulence genes and antimicrobial resistance genes in Salmonella enterica serovar 4,[5],12:i:- isolates from Guizhou Province, China.
The study identified multiple antimicrobial resistance genes, including bla TEM-1, strA-strB, sul2, tetB, and bla CTX-M, in Salmonella enterica serovar 4,[5],12:i:- isolates from Guizhou, China, highlighting the high prevalence of multidrug resistance.
Antibiotic Resistance in Non-Typhoidal Salmonella enterica Strains Isolated from Chicken Meat in Indonesia.
The study identified several AMR genes, including blaTEM, aadA, tetA, and tetB, in NTS strains from chicken meat in Indonesia. Additionally, mutations in gyrA were linked to resistance to nalidixic acid and ciprofloxacin.
Evaluating the potential of third generation metagenomic sequencing for the detection of BRD pathogens and genetic determinants of antimicrobial resistance in chronically ill feedlot cattle.
The study identified various antimicrobial resistance genes (ARGs) in metagenomic sequencing data from chronically ill feedlot cattle, including genes conferring resistance to beta-lactams, aminoglycosides, macrolides, phenicols, tetracyclines, and trimethoprim. Notably, tetH was the most frequently detected resistance gene, and several ARGs were found to be associated with integrative and conjugative elements (ICEs).
Escherichia coli ST1193: Following in the Footsteps of E. coli ST131
The paper characterizes Escherichia coli ST1193 as an emerging multidrug-resistant clone with various AMR determinants, including beta-lactamases (bla CTX-M-15, bla CTX-M-14, bla CTX-M-27, bla CTX-M-55, bla OXA-1, bla TEM-1, bla CMY-42, bla CMY-2), aminoglycoside-modifying enzymes (aac(3)-IIa, aac(3)-IId, aac(6′)-Ib-cr, aadA1, aadA2, aadA5, aph(3′′)-Ib, aph(6)-Id), and other resistance genes (mcr-1, mph(A), erm(B), dfrA8, dfrA12, dfrA17, sul1, sul2, tetA, tetB).
The occurrence of antimicrobial residues and antimicrobial resistance genes in urban drinking water and sewage in Southern Brazil.
The study identified the presence of antimicrobial resistance genes (ARGs) such as blaTEM and tetB in drinking water samples, along with antimicrobial residues like doxycycline. It also found various ARGs in sewage samples, highlighting the importance of water sources as reservoirs of AMR.
Occurrence of antibiotics and bacterial resistance genes in wastewater: resistance mechanisms and antimicrobial resistance control approaches.
The study identifies several AMR genes and mutations associated with resistance to various antibiotics in wastewater environments, highlighting the role of these genes in the spread of antimicrobial resistance.
Antibiotic resistance genes of public health importance in livestock and humans in an informal urban community in Nepal.
The study identified several antibiotic resistance genes, including bla SHV-1, QnrS, ermC, tetA, tetB, aacC2, and aadA1, in various sources such as humans, animals, and water in an urban informal settlement in Nepal.
Molecular characterisation of Acinetobacter baumannii isolates from bloodstream infections in a tertiary-level hospital in South Africa.
The study identified colistin-resistant Acinetobacter baumannii isolates with resistance genes including bla OXA-23, bla NDM-1, lps B, and various efflux pumps. These isolates exhibited extensive drug resistance (XDR) and were associated with sequence types ST1 and ST2.
Comparative Genomics Analysis and Outer Membrane Vesicle-Mediated Horizontal Antibiotic-Resistance Gene Transfer in Avibacterium paragallinarum.
The study identified 11 antibiotic resistance genes (ARGs) in Avibacterium paragallinarum P4chr1, including bl2d_oxa1, aph33ib, cml_e3, and tetB, which confer resistance to beta-lactam, aminoglycoside, phenicol, and tetracycline antibiotics, respectively. These ARGs were transferred via outer membrane vesicles (OMVs) to a susceptible strain, although the resistance was transient.
World Health Organization critical priority Escherichia coli clone ST648 in magnificent frigatebird (Fregata magnificens) of an uninhabited insular environment.
The study identified a multidrug-resistant ST648 E. coli isolate carrying various AMR genes, including blaCTX-M-2, blaCMY-2, qnrB, tetB, sul1, sul2, aadA1, aac(3)-VIa, and mdfA, highlighting the presence of critical priority pathogens in wild birds.
Antimicrobial Resistance: Mechanisms, Spread, and Control
The paper discusses the prevalence and mechanisms of antimicrobial resistance, focusing on tetracycline resistance genes such as tetA, tetB, tetC, tetD, tetE, tetI, and tetY in Escherichia coli. These genes are associated with efflux mechanisms that contribute to resistance against tetracycline.
Molecular characterization of multi drug resistant Escherichia coli isolates at a tertiary hospital in Abuja, Nigeria.
The study identified several AMR genes in multi-drug resistant E. coli isolates, including bla CTX-M-15, bla CTX-M-14, bla CTX-M-27, bla CTX-M-65, bla OXA-1, bla OXA-2, bla CMY-2, bla NDM-1, bla NDM-5, aac(3)-IId, aac(3)-IIe, aac(6')-Ib-cr, aad A5, ant(2′′)-Ia, aph(3′′)-Ib, aph(3′′)-VI, aph(6)-Id, ermB, ermD, fosA3, fosA7, mdtM, emrD, sul1, sul2, sul3, tetA, tetB, tetM, dfrA1, dfrA7, dfrA8, dfrA12, dfrA14, dfrA17, dfrA82, dfrB4, qepA, qepA1, qepA2, qepA4, qnrB19, qnrS1, qacE, catA1, catA2, catB3, cmlA1, mphA.
Urban rats as carriers of invasive Salmonella Typhimurium sequence type 313, Kisangani, Democratic Republic of Congo.
The study identified multidrug-resistant Salmonella Typhimurium ST313 in urban rats in Kisangani, Democratic Republic of Congo, highlighting their potential role as reservoirs of invasive Salmonella. The resistant isolates carried genes such as blaTEM-1, strA, strB, ant(3')-Ia, aac(3')-IId, sul1, sul2, dfrA1, tetB, and catA10, conferring resistance to multiple antibiotics.
Whole-genome sequencing-based characteristics of Escherichia coli Rize-53 isolate from Turkey.
The study identified ten antibiotic resistance genes in the E. coli Rize-53 isolate, including blaOXA-1, blaOXA-2, aac(6')-II, aac(6')-Ib-cr, tetB, catB3, qacE, sitABCD, mdfA, and sul2, which confer resistance to various antibiotics such as beta-lactams, aminoglycosides, tetracyclines, chloramphenicol, sulfonamides, and quaternary ammonium compounds.
Molecular Typing Reveals Environmental Dispersion of Antibiotic-Resistant Enterococci under Anthropogenic Pressure.
The study identified multiple antibiotic resistance genes in Enterococcus isolates from various aquatic environments, highlighting the role of anthropogenic pressure in the spread of antibiotic-resistant enterococci.
Antimicrobial Resistance Pattern, Clustering Mechanisms and Correlation Matrix of Drug-Resistant Escherichia coli in Black Bengal Goats in West Bengal, India.
The study identified several AMR genes in multidrug-resistant E. coli isolates from goats, including bla CTXM-1, bla AmpC, bla SHV, bla TEM, bla CMY-6, bla CITM, bla NDM-5, qnr B, qnr S, aac(6')-Ib-cr, tet A, tet B, sul 1, and the acrAB efflux pump system.
Antibacterial and antibiofilm effects of essential oil components, EDTA and HLE disinfectant solution on Enterococcus, Pseudomonas and Staphylococcus sp. multiresistant strains isolated along the meat production chain.
The study identified several AMR genes in Enterococcus, Pseudomonas, and Staphylococcus sp. strains, including beta-lactamases, chloramphenicol acetyltransferases, macrolide resistance determinants, efflux pump genes, and sulfonamide resistance proteins. These genes contribute to resistance against various antibiotics such as beta-lactams, chloramphenicol, aminoglycosides, tetracyclines, and sulfonamides.
Commensal bacteria contribute to the growth of multidrug-resistant Avibacterium paragallinarum in chickens.
The study identifies multiple AMR genes in multidrug-resistant Avibacterium paragallinarum, including tetB, bla CTX-M-14, bla OXA-1, bla ROB-1, mef(B), ant, aac, and aph, which confer resistance to tetracycline, ampicillin, erythromycin, tylosin, and gentamicin.
Occurrence of virulence factors and carbapenemase genes in Salmonella enterica serovar Enteritidis isolated from chicken meat and egg samples in Iraq.
The study identified carbapenemase genes blaIMP, blaOXA-48-like, and blaNDM, along with tetracycline resistance genes tetA and tetB, and trimethoprim-sulfamethoxazole resistance genes dfrA1 and sul1 in Salmonella enterica serovar Enteritidis isolates from chicken meat and eggs in Iraq.
Characterisation and antibiotic resistance of Yersinia enterocolitica from various meat categories, South Africa.
The study identified blaTEM, cmlA, and tetB as the primary antimicrobial resistance genes in Y. enterocolitica isolates from meat products in South Africa, with high prevalence of resistance to ampicillin, cephalothin, and tetracycline.
Diversity of resistant determinants, virulence factors, and mobile genetic elements in Acinetobacter baumannii from India: A comprehensive in silico genome analysis.
The study identified multiple antibiotic resistance genes (ARGs) in 47 Acinetobacter baumannii isolates from India, including blaOXA-23, blaADC-73, aac(3)-I, aadA, aph(3')-Ib, sul1, sul2, and lpsB. These genes contribute to resistance against carbapenems, cephalosporins, aminoglycosides, sulfonamides, and polymyxins.
The pan-genome of the emerging multidrug-resistant pathogen Corynebacterium striatum.
The study identifies 15 antimicrobial resistance genes in Corynebacterium striatum, including genes conferring resistance to aminoglycosides, tetracyclines, chloramphenicol, macrolides, lincosamides, streptogramins, sulfonamides, and cationic antiseptics. These genes are often located in genomic islands and mobile genetic elements, highlighting the role of horizontal gene transfer in the spread of multidrug resistance.
Extended Spectrum β-Lactamase-Producing Escherichia coli from Poultry and Wild Birds (Sparrow) in Djelfa (Algeria), with Frequent Detection of CTX-M-14 in Sparrow.
The study identifies the bla CTX-M-14 gene in Escherichia coli isolates from sparrows, along with bla CTX-M-15 and bla CTX-M-1 in turkey and chicken isolates, highlighting the role of wild birds in the dissemination of antibiotic resistance.
In Vitro Assessment of Antimicrobial Activity of Phytobiotics Composition towards of Avian Pathogenic Escherichia coli (APEC) and Other E. coli Strains Isolated from Broiler Chickens.
The study identifies several AMR genes in E. coli strains, including aadA, strA/strB, aphA1, aphA2, tetA, tetB, sul1, sul2, sul3, dfrA1, dfrA10, dfrA12, floR, and blaSHV, which confer resistance to various antibiotics such as streptomycin, neomycin, tetracycline, sulfonamides, trimethoprim, chloramphenicol, and cephalosporins.
A Familiar Outbreak of Monophasic Salmonella serovar Typhimurium (ST34) Involving Three Dogs and Their Owner's Children.
The study identified AMR genes sul2, tetB, and blaTEM-1B in a monophasic Salmonella Typhimurium ST34 outbreak involving humans and dogs.
Multidrug-Resistant Bacteria in a COVID-19 Hospital in Zagreb.
The study identified several AMR genes in multidrug-resistant bacteria isolated from a COVID-19 hospital in Zagreb, including bla CTX-M-15 in E. coli and various bla OXA variants in A. baumannii. These genes conferred resistance to beta-lactams and aminoglycosides.
A Cross-Validated Feature Selection (CVFS) approach for extracting the most parsimonious feature sets and discovering potential antimicrobial resistance (AMR) biomarkers.
The study presents a Cross-Validated Feature Selection (CVFS) approach for identifying the most parsimonious gene sets for predicting antimicrobial resistance (AMR) from bacterial pan-genomes. The CVFS approach was able to extract both known and novel AMR genes, demonstrating its effectiveness in selecting relevant features for AMR prediction.
Phylogenetic analysis and antibiotic resistance of Escherichia coli isolated from wild and domestic animals at an agricultural land interface area of Salaphra wildlife sanctuary, Thailand.
The study identified several AMR genes in E. coli isolates from wild and domestic animals in Thailand, including blaTEM, blaSHV, blaCMY-2, aac(3)-IV, aadA, tetA, tetB, qnrA, sul3, dfrA1, dfrA5, and dfrA7, which conferred resistance to various antibiotics such as ampicillin, gentamicin, tetracycline, ciprofloxacin, and trimethoprim-sulfamethoxazole.
Prevalence and abundance of antibiotic-resistant genes in culturable bacteria inhabiting a non-polar passu glacier, karakorum mountains range, Pakistan.
The study identified multiple antibiotic-resistant genes (ARGs) in culturable bacteria from a non-polar glacier in Pakistan, highlighting the presence of resistance mechanisms against various antibiotics.
Molecular and Antimicrobial Susceptibility Characterization of Escherichia coli Isolates from Bovine Slaughterhouse Process.
The study identified several AMR genes including tetA, strB, aadA, tetB, aac(3)IV, and strA in E. coli isolates from bovine slaughterhouse samples, highlighting the prevalence of tetracycline and streptomycin resistance.
Multidrug-resistant extended spectrum β-lactamase (ESBL)-producing Escherichia coli from farm produce and agricultural environments in Edo State, Nigeria.
The study identified various AMR genes in ESBL-producing E. coli isolates from agricultural farms and open markets in Edo State, Nigeria, including blaTEM, blaCTX-M-1, blaCTX-M-15, tetM, tetA, tetB, sul1, sul2, sul3, ant(4')-Ia, aacC(3)-1, qnrA, qnrB, qnrC, qnrS, cat::pC194, cat::pC221, intI1, and intI2. These genes conferred resistance to multiple antibiotics, indicating the presence of multidrug-resistant E. coli in the studied environments.
Detection of antimicrobial resistance genes in Lactobacillus spp. from poultry probiotic products and their horizontal transfer among Escherichia coli.
The study identified antimicrobial resistance genes (ARGs) in Lactobacillus spp. from poultry probiotic products, including bla TEM, bla CTX-M-1, bla CTX-M-2, qnr S, tet A, and tet B. These genes were horizontally transferred to E. coli during co-culture, highlighting the potential risk of AMR spread in poultry populations.
Phenotypic and genotypic survey of antibiotic resistance in Salmonella enterica isolates from dairy farms in Uruguay.
The study identified 21 AMR genes in Salmonella enterica isolates from dairy farms in Uruguay, including genes conferring resistance to aminoglycosides, tetracyclines, sulfonamides, beta-lactams, and quinolones. Two chromosomal mutations, parC_T57S and acrB_R717Q, were also detected, contributing to resistance against quinolones and azithromycin, respectively.
Analysis of Antimicrobial Resistance Genes (ARGs) in Enterobacterales and A. baumannii Clinical Strains Colonizing a Single Italian Patient.
The study identified various antimicrobial resistance genes in Enterobacterales and A. baumannii clinical strains from a single patient, highlighting the presence of blaNDM-1, qnrS1, aadA1, strA-strB, sul2, tet(J), catA1, blaACT-15, blaTEM-1B, dfrA14, oqxB, fosA, blaLEN-22, blaOXA-23, blaADC-25, blaOXA-66, armA, mph(E), msr(E), and tetB, indicating multidrug resistance and potential for horizontal gene transfer.
Prevalence and Characterization of Salmonella Isolated from Chickens in Anhui, China.
The study identified several AMR genes in Salmonella isolates from chickens in Anhui, China, including blaTEM, blaCMY-2, aadA, strA, aph(3')-IIa, aac(6')-Ib-cr, qnrB, qnrS, sul1, sul2, tetA, tetB, cat1, and floR. These genes were associated with resistance to various antibiotics such as ampicillin, cephalosporins, streptomycin, gentamicin, amikacin, fluoroquinolones, sulfamethoxazole, tetracycline, chloramphenicol, and florfenicol.
High frequency of NDM-1 and OXA-48 carbapenemase genes among Klebsiella pneumoniae isolates in central Iran.
The study identified high frequencies of bla TEM, bla CTX-M1, bla SHV, bla CTX-M15, bla CIT, bla CMY-2, bla NDM, bla OXA-48, qnrB, qnrS, qnrA, tetA, tetB, sul1, sul2, int1, and int2 genes in Klebsiella pneumoniae isolates from central Iran, highlighting the prevalence of multidrug-resistant and carbapenem-resistant strains.
Distribution analysis of tetracycline resistance genes in Escherichia coli isolated from floor surface and effluent of pig slaughterhouses in Banten Province, Indonesia.
The study identified the distribution of tetracycline resistance genes (tetA, tetB, tetC, tetE, tetM, tetO, and tetX) in Escherichia coli isolates from pig slaughterhouses in Banten Province, Indonesia. The tetO gene was the most dominant in floor surface samples, while tetA was dominant in effluent samples.
Prevalence and resistance to antibacterial agents in Salmonella enterica strains isolated from poultry products in Northern Kazakhstan.
The study identified several AMR genes in Salmonella enterica strains from poultry products in Northern Kazakhstan, including tetA, tetB, blaTEM, aadA, sul3, catII, and cmlA, which confer resistance to various antibiotics such as tetracycline, beta-lactams, aminoglycosides, sulfonamides, and chloramphenicol.
Potential Use of a Combined Bacteriophage-Probiotic Sanitation System to Control Microbial Contamination and AMR in Healthcare Settings: A Pre-Post Intervention Study.
The study evaluated the effectiveness of a combined probiotic-phage sanitation system (PCHSφ) in reducing microbial contamination and antimicrobial resistance (AMR) in hospital environments. PCHSφ significantly reduced staphylococcal contamination and AMR gene prevalence compared to conventional chemical disinfection and PCHS alone.
The Genetic and Phenotypic Diversity of Bacillus spp. from the Mariculture System in China and Their Potential Function against Pathogenic Vibrio.
The study identified three antibiotic resistance genes, tetB, blaTEM, and cfr, in Bacillus isolates from Chinese mariculture systems, highlighting their potential impact on antimicrobial resistance.
Phenotypic and Genotypic Characteristics of Antimicrobial Resistance in Citrobacter freundii Isolated from Domestic Ducks (Anas platyrhynchos domesticus) in Bangladesh.
The study identified multiple AMR genes in Citrobacter freundii isolates from domestic ducks in Bangladesh, including beta-lactamases (bla TEM-1, bla CMY-2, bla CMY-9, bla CTX-M-14), sulfonamide resistance genes (sul1, sul2), tetracycline resistance genes (tetA, tetB), fluoroquinolone resistance genes (qnrA, qnrB, qnrS), and an aminoglycoside resistance gene (aacC4).
Occurrence of High-Risk Clonal Lineages ST58, ST69, ST224, and ST410 among Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolated from Healthy Free-Range Chickens (Gallus gallus domesticus) in a Rural Region in Tunisia.
The study identified high-risk clonal lineages ST58, ST69, ST224, and ST410 among ESBL-producing E. coli isolates from free-range chickens in Tunisia. Key AMR genes included bla CTX-M-1, bla CTX-M-15, bla CTX-M-55, aac(6')-Ib-cr, qnrS, qnrB, tetB, tetA, sul1, sul2, and mcr-2.
Molecular epidemiology of enterically colonizing Escherichia coli with resistance against third-generation cephalosporins isolated from stool samples of European soldiers with concomitant diarrhea on deployment in Western African Mali.
The study identified bla CTX-M-15 and bla TEM-1b as the primary genes responsible for third-generation cephalosporin resistance in E. coli isolates from European soldiers in Mali. Additionally, several quinolone resistance genes including qnrS1, gyrA S83L, gyrA D87N, parE S458T, parE S458A, and parC S80I were found. Trimethoprim-sulfamethoxazole resistance was mediated by sul1, sul2, dfrA1, dfrA5, dfrA14, and dfrA17. Gentamicin resistance was associated with aph6-Id, aph3-Ib, aac3-IId, aadA5, and aac6-Ib-cr5. Tetracycline resistance was conferred by tetA, tetB, and tetD.
Antimicrobial resistance and virulence genes of invasive Salmonella enterica from children with bacteremia in north-central Nigeria.
The study identified multiple antimicrobial resistance genes in invasive Salmonella enterica isolates from children with bacteremia in north-central Nigeria, including bla TEM, flo R, qnr A, tet A, tet B, and tet G. These genes conferred resistance to various antibiotics such as ampicillin, trimethoprim-sulfamethoxazole, chloramphenicol, tetracycline, and ciprofloxacin.
Resistance mechanisms of tigecycline in Acinetobacter baumannii.
The study identifies several efflux pumps, outer membrane permeability alterations, and antibiotic target modifications as key mechanisms of tigecycline resistance in Acinetobacter baumannii.
Antimicrobial resistance and molecular characterization of Escherichia coli isolated from bovine mastitis samples in Nghe An province, Vietnam.
The study identified tetracycline resistance genes tetA and tetB, sulfonamide resistance genes sul1 and sul2, and no extended-spectrum beta-lactamase (ESBL) genes in E. coli isolates from bovine mastitis in Vietnam.
Concordance between Genotypic and Phenotypic Drug-Resistant Profiles of Shigella Isolates from Taiyuan City, Shanxi Province, China, 2005 to 2016.
The study identified various AMR genes and mutations in Shigella isolates from Taiyuan City, including beta-lactamases (blaTEM-1, blaOXA-1, blaCTX-M-14, blaCTX-M-55), quinolone resistance genes (qnrS1), aminoglycoside resistance genes (aac(3)-IId), tetracycline resistance genes (tetA, tetB), macrolide resistance genes (mphA, ermB), and chloramphenicol resistance gene (catI). Mutations in gyrA and parC were associated with fluoroquinolone resistance.
Role of multidrug resistance and co-resistance on a high percentage of streptomycin resistance in Escherichia coli isolated from chicken meats in Japan.
The study identifies multiple AMR genes, including strA/strB, blaTEM, tetB, aphA1, dfrA14, dfrA17, and cat1, which contribute to multidrug resistance in Escherichia coli isolated from chicken meats in Japan.
Food risk associated with vegetable consumption, exposure to antimicrobial-resistant strains and pesticide residues.
The study identified several antimicrobial resistance genes in AMR strains isolated from vegetables, including blaTEM, tetA, tetW, tetC, tetD, tetB, qnrS, and sulI. These genes conferred resistance to various antibiotics such as ampicillin, amoxicillin/clavulanic acid, tetracycline, ciprofloxacin, nalidixic acid, and trimethoprim/sulfamethoxazole.
CTX-M-producing Escherichia coli ST602 carrying a wide resistome in South American wild birds: Another pandemic clone of One Health concern.
The study identifies two CTX-M-producing E. coli ST602 strains, UNB7 and GP188, from wild birds in Brazil and Chile, carrying a wide resistome against antibiotics, heavy metals, disinfectants, and herbicides.
Dominance of Escherichia coli sequence types ST73, ST95, ST127 and ST131 in Australian urine isolates: a genomic analysis of antimicrobial resistance and virulence linked to F plasmids.
The study identified various antimicrobial resistance genes in E. coli isolates from Australian urine samples, including blaCTX-M-15, blaCTX-M-14, blaTEM-28, sul1, sul2, sul3, dfrA17, dfrA5, dfrA1, dfrB4, tetA, tetB, mphA, cmlA1, cmlA5, catB3, sat2, qnrD1, fosA7, aac(3)-IId, aac(3)-IIe, aph(3')-IIa, aph(6)-Id, ant(3'')-IIa, intI1, and intI2. These genes were associated with resistance to various antibiotics such as beta-lactams, sulfonamides, trimethoprim, tetracycline, macrolides, chloramphenicol, streptothricin, quinolones, fosfomycin, and aminoglycosides.
Pathogenicity and Antibiotic Resistance Diversity in Clostridium perfringens Isolates from Poultry Affected by Necrotic Enteritis in Canada.
The study identified several antimicrobial resistance genes in Clostridium perfringens isolates from poultry with necrotic enteritis, including tetA, tetB, tet44, InuP, erm(T), and ant(6)-Ib. The erm(T) gene was reported for the first time in C. perfringens and conferred resistance to erythromycin.
Isolation and characterization of multidrug resistant Gallibacterium anatis biovar haemolytica strains from Polish geese and hens.
The study identified 25 different antimicrobial resistance genes in multidrug-resistant Gallibacterium anatis biovar haemolytica strains from Polish geese and hens, including tetB, blaTEM-1, blaROB-1, floR, sul2, sul3, dfrK, aadA1, aadA2, aph(3)-la, aph(3)-lb, aph(6)-ld, sat2, dfrA14, dfrA32, merC, merP, merR, merT, qacL, and cmlA1.
Phenotypic and genotypic antimicrobial resistance correlation and plasmid characterization in Salmonella spp. isolates from Italy reveal high heterogeneity among serovars.
The study identified several antimicrobial resistance genes including blaTEM-1B, sul1, sul2, tetA, tetB, and others in Salmonella isolates from Italy, highlighting the diversity of resistance mechanisms among different serovars.
Antibiotic Resistance Mediated by Escherichia coli in Kuwait Marine Environment as Revealed through Genomic Analysis.
The study identified various antibiotic resistance genes in Escherichia coli isolates from Kuwait's marine environment, including beta-lactamases, aminoglycoside-modifying enzymes, fluoroquinolone resistance genes, sulfonamide resistance genes, tetracycline resistance genes, and macrolide resistance genes. Additionally, the MFS-type drug efflux gene mdfA was commonly found in E. coli isolates.
Detection of tetracycline resistance genes and their diversity in Escherichia coli isolated from pig farm waste in Banten province, Indonesia.
The study identified several tetracycline resistance genes, including tetA, tetB, tetC, tetM, tetO, and tetX, in Escherichia coli isolated from pig farm waste in Banten province, Indonesia. tetX and tetO were the most prevalent genes, with high frequencies detected in both solid waste and wastewater samples.
Prevalence of Escherichia coli isolated from oropharynx and trachea of clinically sick poultry and antimicrobial resistance pattern of the strains isolated.
The study identified the presence of tetA, tetB, and tetC genes in tetracycline-resistant E. coli isolates from poultry, highlighting the role of these genes in oxytetracycline resistance.
Distribution of Antibiotic Resistance in a Mixed-Use Watershed and the Impact of Wastewater Treatment Plants on Antibiotic Resistance in Surface Water.
The study identified several antibiotic resistance genes (ARGs) in surface water and wastewater, including ermB, qnrS, blaKPC, blaSHV, blaCTX-M, and tetB, highlighting the presence of multidrug-resistant bacteria and the role of wastewater treatment plants in spreading antibiotic resistance.
Antimicrobial Resistant Bacteria Monitoring in Raw Seafood Retailed: a Pilot Study Focused on Vibrio and Aeromonas.
The study identified tetracycline, sulfamethoxazole, and trimethoprim/sulfamethoxazole resistance genes (tetD, tetB, tetM, tetE, sul1, sul2, and dfrA) in Vibrio and Aeromonas isolates from raw seafood samples in Japan.
Characteristics of antimicrobial resistance in Escherichia coli isolated from retail meat products in North Carolina.
The study identified several AMR genes in E. coli isolates from retail meat products in North Carolina, including aac(3)-IV, aadA1, aph(3'')-lb, blaTEM-1, tetB, and others, highlighting the prevalence of multidrug-resistant E. coli in ground turkey.
Metagenomic assembly is the main bottleneck in the identification of mobile genetic elements.
The study evaluated the performance of tools for identifying mobile genetic elements (MGEs) and antimicrobial resistance genes (ARGs) in metagenomic data. It found that metagenomic assembly is the main bottleneck in accurately identifying MGEs and ARGs, with moderate precision and sensitivity for plasmids, phages, IS elements, and ARGs.
Genomic insights into ESBL-producing Escherichia coli isolated from non-human primates in the Peruvian Amazon.
The study identified three bla CTX-M variants (bla CTX-M-15, bla CTX-M-55, and bla CTX-M-65) and a broad resistome in ESBL-producing E. coli strains isolated from non-human primates in the Peruvian Amazon.
Meat and meat products as potential sources of emerging MDR Bacillus cereus: groEL gene sequencing, toxigenic and antimicrobial resistance.
The study identified multiple antimicrobial resistance genes, including bla1, bla2, ermA, tetA, and tetB, in multidrug-resistant Bacillus cereus isolates from meat and meat products.
Genomic Features and Phylogenetic Analysis of Antimicrobial-Resistant Salmonella Mbandaka ST413 Strains.
The study identified nine resistance genes, including aac(6')-Iaa, sul1, qacE, blaOXA-129, tet(B), and aadA1, as well as a point mutation in ParC (T57S) associated with quinolone resistance in Salmonella Mbandaka ST413 strains.
Occurrence and molecular characteristics of antimicrobial resistance, virulence factors, and extended-spectrum β-lactamase (ESBL) producing Salmonella enterica and Escherichia coli isolated from the retail produce commodities in Bangkok, Thailand.
The study identified several AMR genes and mutations in Salmonella enterica and Escherichia coli isolated from retail produce in Bangkok, Thailand. Key findings include the presence of bla TEM, qnrS, tetA, tetB, strA, and strB genes, as well as gyrA and parC mutations associated with ciprofloxacin resistance.
Multilocus sequence typing and antibiotic resistance of Aeromonas isolated from freshwater fish in Hebei Province.
The study identified several AMR genes in Aeromonas isolates from freshwater fish in Hebei Province, including TEM, tetA, floR, sul2, Ant(3")-I, and qacEΔ1, which confer resistance to various antibiotics such as penicillin, tetracycline, chloramphenicol, sulfonamide, aminoglycoside, and quinolone.
Comparison of genotypic and phenotypic antimicrobial resistance profiles of Salmonella enterica isolates from poultry diagnostic specimens.
The study identified 31 AMR genes in 97 Salmonella enterica isolates from poultry, including aac(3)-IId, aac(3)-IVa, aac(3)-VIa, aac(6′)-Ib4, ant(2′′)-Ia, grdA, aph(3′)-Ia, aph(3′)-IIa, aadA1, aadA2, aadA7, aadA13, aph(3′)-Ib, aph(6)-Ic, aph(6)-Id, aph(4)-Ia, blaCMY-2, blaCTX-M-1, blaHER-3, blaTEM-1, floR, tetA, tetB, tetC, dfrA12, sul1, sul2, fosA7, qnrB19, ble, and mcr-9.
Antimicrobial resistance of avian pathogenic Escherichia coli isolated from broiler, layer, and breeder chickens.
The study identified multiple antibiotic resistance genes in avian pathogenic Escherichia coli (APEC) isolates from commercial chickens in Nepal, including blaTEM, sul1, qnrA, tetB, cat1, ereA, mcr1, and aac(3)-IV, which confer resistance to various antimicrobial agents.
Suppression PCR-Based Selective Enrichment Sequencing for Pathogen and Antimicrobial Resistance Detection on Cell-Free DNA in Sepsis-A Targeted, Blood Culture-Independent Approach for Rapid Pathogen and Resistance Diagnostics in Septic Patients.
The study presents a novel method called SUPSETS for detecting pathogens and antimicrobial resistance genes (AMRs) in sepsis using cell-free DNA. It identifies tetracycline resistance (tetB), vancomycin resistance (vanA), and macrolide resistance (ermB) in clinical samples.
Molecular and clinical epidemiology of carbapenem resistant Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacterales in Fiji: a multicentre prospective observational study.
The study identified several carbapenem-resistant genes, including bla OXA-23, bla OXA-66, bla NDM-1, bla OXA-50, bla OXA-395, bla NDM-7, and bla NDM-5, in various bacterial species in Fiji.
Genomic characterization of multi drug resistant ESBL-producing Escherichia coli isolates from patients and patient environments in a teaching hospital in Ghana.
The study identified multiple AMR genes in ESBL-producing E. coli isolates from patients and the hospital environment, including bla CTX-M-15, bla TEM-1B, bla OXA-1, and various aminoglycoside, macrolide, tetracycline, sulfonamide, and trimethoprim resistance genes. Additionally, PMQR genes like qnrS1, qnrB19, qnrB4, and qepA4 were detected, contributing to quinolone resistance.
Molecular Characterization and Antibacterial Resistance Determination of Escherichia coli Isolated from Fresh Raw Mussels and Ready-to-Eat Stuffed Mussels: A Major Public Health Concern.
The study identified several AMR genes in E. coli isolates from mussels, including tetB, sul1, sul2, floR, qnrA, and qnrB, which confer resistance to tetracycline, sulfonamides, chloramphenicol, and fluoroquinolones.
Multi-drug resistant (MDR) Gram-negative pathogenic bacteria isolated from poultry in the Noakhali region of Bangladesh.
The study identified multiple AMR genes, including blaTEM, blaSHV, tetA, tetB, sul1, sul2, and mcr-1, in various multidrug-resistant Gram-negative bacteria isolated from poultry in Bangladesh. These genes conferred resistance to a wide range of antibiotics, highlighting the significant public health concerns associated with AMR in poultry.
The synergy effect of matrine and berberine hydrochloride on treating colibacillosis caused by an avian highly pathogenic multidrug-resistant Escherichia coli.
The study identified multiple antibiotic resistance genes in a multidrug-resistant Escherichia coli strain, including blaTEM, ermA, ermB, aadA1, qnrS, qepA, oqxA, tetA, tetB, and tetC, which conferred resistance to various antibiotics such as beta-lactams, macrolides, aminoglycosides, quinolones, and tetracyclines. The combination of matrine and berberine hydrochloride showed synergistic antibacterial effects against this strain.
Assessment of the presence of multidrug-resistant Escherichia coli, Salmonella and Staphylococcus in chicken meat, eggs and faeces in Mymensingh division of Bangladesh.
The study identified multiple AMR genes in E. coli, Salmonella spp., and Staphylococcus aureus isolated from chicken meat, eggs, and faeces in Bangladesh, highlighting the presence of multidrug-resistant pathogens.
Whole-genome sequencing of two multidrug-resistant acinetobacter baumannii strains isolated from a neonatal intensive care unit in Egypt: a prospective cross-sectional study.
The study identified multidrug-resistant Acinetobacter baumannii strains from a neonatal ICU in Egypt, highlighting the presence of various beta-lactamase genes, aminoglycoside resistance genes, macrolide resistance genes, tetracycline resistance genes, and sulfonamide resistance genes.
Determinants of Antibiotic Resistance and Virulence Factors in the Genome of Escherichia coli APEC 36 Strain Isolated from a Broiler Chicken with Generalized Colibacillosis.
The study identifies multiple antibiotic resistance genes in the E. coli APEC 36 strain, including beta-lactamases, aminoglycoside modifying enzymes, fluoroquinolone resistance genes, and efflux pumps, indicating a high level of multidrug resistance.
Molecular Characterization of Multidrug-Resistant Escherichia coli from Fecal Samples of Wild Animals.
The study identified multiple AMR genes in E. coli isolates from wild animals, including beta-lactamases (bla TEM-1B, bla CTX-M-65, bla CTX-M-55, bla EC-1982), aminoglycoside resistance genes (aac(3)-IIa, aadA2, aadA5, ant(3")-Ia, aph(3")-Ib, aph(3′)-Ia, aph(6)-Id), tetracycline resistance genes (tetB, tetA), trimethoprim resistance genes (dfrA17, dfrA1, dfrA5, dfrA12), sulfonamide resistance genes (sul1, sul2, sul3), macrolide/lincosamide/streptogramin resistance genes (mphB, lnuF, ermC, mefC), quinolone resistance genes (qnrB19, qnrB5, qnrS1, qnrS2), and others. Additionally, point mutations in gyrA, parC, and parE were associated with fluoroquinolone resistance.
Molecular Characterization of Multidrug-Resistant Escherichia coli from Fecal Samples of Wild Animals.
The study identified multiple AMR genes in E. coli isolates from wild animals, including beta-lactamases (bla TEM-1B, bla CTX-M-65, bla CTX-M-55, bla EC-1982), aminoglycoside resistance genes (aac(3)-IIa, aadA2, aadA5, ant(3")-Ia, aph(3")-Ib, aph(3′)-Ia, aph(6)-Id), tetracycline resistance genes (tetB, tetA), trimethoprim resistance genes (dfrA17, dfrA1, dfrA5, dfrA12), sulfonamide resistance genes (sul1, sul2, sul3), macrolide/lincosamide/streptogramin resistance genes (mphB, lnuF, ermC, mefC), quinolone resistance genes (qnrB19, qnrB5, qnrS1, qnrS2), and others. Additionally, point mutations in gyrA, parC, and parE were associated with fluoroquinolone resistance.
Assessment of Bacterial Contamination and Antimicrobial Resistance of Escherichia coli Isolates from Slovak Dairy Farms.
The study identified several antimicrobial resistance genes in E. coli isolates from Slovak dairy farms, including bla TEM, bla SHV, bla CMY, sul 1, sul 2, tet B, and qnr S, which confer resistance to various antibiotics such as beta-lactams, sulfonamides, tetracyclines, and quinolones.
Genome and antibiotic resistance characteristics of Shigella clinical isolates in Fujian Province, Southeast China, 2005-2019.
The study identified various AMR genes in Shigella isolates from Fujian Province, including beta-lactamases (bla TEM-1, bla OXA-1, bla CTX-M-14, bla CTX-M-15, bla CTX-M-55, bla CTX-M-64), macrolide resistance genes (mphA, ermB), tetracycline resistance genes (tetA, tetB), aminoglycoside resistance genes (aadA, aph(3')-Ib, aac(3)-IId), chloramphenicol resistance gene (catA1), and sulfonamide/trimethoprim resistance genes (sul1, sul2, dfrA1, dfrA12, dfrA14, dfrA17).
The role of New World vultures as carriers of environmental antimicrobial resistance.
The study identified several antimicrobial resistance genes (ARGs) in environmental samples collected from New World vultures, including blaTEM, sul1, ermA, ermF, tetA, and tetB, which confer resistance to beta-lactams, sulfonamides, macrolides, and tetracyclines. These genes were detected in Escherichia coli, enterococci, and Salmonella spp. across different sampling sites and seasons.
Fecal carriage of ESBL-producing E. coli and genetic characterization in rural children and livestock in the Somali region, Ethiopia: a one health approach.
The study identified bla CTX-M-15 as the most prevalent ESBL gene in both human and animal E. coli isolates, along with other resistance genes such as bla TEM-1B, bla OXA-1, and various aminoglycoside, sulfonamide, and trimethoprim resistance genes. Mutations in gyrA, parC, and parE were also associated with fluoroquinolone resistance.
Epidemiology and Molecular Characterisation of Multidrug-Resistant Escherichia coli Isolated from Cow Milk.
The study identified several AMR genes in multidrug-resistant E. coli isolates from cow milk, including bla TEM, bla CTX-M, bla OXA-1, bla OXA-2, bla CMY-1, tet A, tet B, tet D, sul -1, and sul -2, which confer resistance to various antibiotics.
Molecular Epidemiology and Genetic Characterization of Carbapenem-Resistant Acinetobacter baumannii Isolates from the ICU of a Tertiary Hospital in East China.
The study identified 48 antimicrobial resistance genes (ARGs) in 39 carbapenem-resistant Acinetobacter baumannii (CRAB) isolates, including blaOXA-66, blaOXA-23, blaADC-30, blaADC-73, gyrA, ant(3")-IIa, aph(3")-Ib, aph(6)-Id, tetB, tetR, sul1, sul2, LpsB, LpxC, and LpxA, which confer resistance to various antibiotics such as carbapenems, cephalosporins, fluoroquinolones, aminoglycosides, tetracycline, and sulfonamides.
Plasmidome of Salmonella enterica serovar Infantis recovered from surface waters in a major agricultural region for leafy greens in California.
The study identified tetracycline resistance genes, including tetB, tetR, tetC, acrAB, and robA, in the IncI plasmid pRM18148 of Salmonella enterica serovar Infantis strains isolated from surface waters in California.
Antibiotic Resistance in Mammalian Wild Game: A Meta-Analysis
The study presents a comprehensive meta-analysis of antibiotic resistance in bacteria isolated from mammalian wild game, highlighting the prevalence of various AMR genes and mutations across different bacterial species.
An exploration of unusual antimicrobial resistance phenotypes in Salmonella Typhi from Blantyre, Malawi reveals the ongoing role of IncHI1 plasmids.
Phenotypic and genotypic characterization of antimicrobial resistance and virulence profiles of Salmonella enterica serotypes isolated from necropsied horses in Kentucky.
The study identified several AMR genes in Salmonella enterica isolates from necropsied horses, including beta-lactamase genes (blaTEM, blaCTX-M, blaSHV2, blaOXA-9), aminoglycoside resistance gene (aacA[3]), sulfonamide resistance gene (sul2), amphenicol resistance gene (floR), tetracycline resistance gene (tetB), streptomycin resistance gene (strA), macrolide resistance gene (ermB2), and quinolone resistance gene (qnrB2). These genes were associated with resistance to multiple antibiotics, highlighting the presence of multidrug-resistant Salmonella strains.
Molecular characterization of resistance and biofilm genes of ESKAPE pathogens isolated from clinical samples: examination of the effect of boric acid on biofilm ability by cell culture method.
The study identified various AMR genes in ESKAPE pathogens, including vanA and vanC for vancomycin resistance, blaKPC and blaOXA-48 for carbapenem resistance, and others related to tetracycline, sulfonamide, quinolone, and aminoglycoside resistance. Additionally, biofilm-related genes such as icaA, icaD, gelE, asa1, and esp were detected in Staphylococcus and Enterococcus spp. Quorum sensing genes LasI and LasR were found in Pseudomonas aeruginosa, and biofilm production genes like mrkA, wbbM, wzm, and luxS were identified in Klebsiella pneumoniae.
Drug resistance and genotyping studies of Salmonella Enteritidis isolated from broiler chickens in Iran.
The study identified several AMR genes in Salmonella Enteritidis isolates from broiler chickens in Iran, including bla TEM, tet A, tet B, sul 1, and str A/B, which conferred resistance to various antibiotics.
Fecal carriage and molecular characterization of carbapenem-resistant Enterobacteriaceae from hospitalized children in a tertiary hospital of Shandong, China.
The study identified bla NDM-1, bla NDM-5, and bla OXA-1 as the most prevalent carbapenemase genes in CRE isolates from hospitalized children in Shandong, China. Additional resistance genes such as bla CTX-M-55, bla CTX-M-15, sul 1, tet A, and mcr-1.26 were also characterized.
Molecular identification of tetracycline resistance genes in Escherichia coli isolates from internal organs of swine sold on Abakaliki, Nigeria.
The study identified the presence of tetracycline resistance genes tetA and tetB in E. coli isolates from swine internal organs in Abakaliki, Nigeria. These genes were found in 75% and 62.5% of the tetracycline-resistant isolates, respectively.
Zoonotic potential of uropathogenic Escherichia coli lineages from companion animals.
The study identified several antimicrobial resistance genes in uropathogenic E. coli strains from companion animals, including blaTEM-1b, sul1, sul2, dfrA1_10, dfrA17_1, dfrA1_8, dfrA7_5, gyrA_S83L, tetA, tetB, aph(6)-Id, aph(3'')-Ib, ant(3'')-Ia, blaCTX-M-15, blaTEM-106, blaSHV-102, and blaCMY-2. These genes confer resistance to various antibiotics such as penicillins, sulfonamides, trimethoprim, quinolones, tetracyclines, streptomycin, and cephalosporins.
A Snapshot of Antimicrobial Resistance in Semi-Wild Oryx: Baseline Data from Qatar.
The study identified tetracycline resistance genes tetA and tetB, as well as bla CTX-M and bla TEM-1 for beta-lactam resistance in E. coli isolates from semi-wild oryx in Qatar. Whole genome sequencing revealed additional resistance mechanisms, including mutations in soxR associated with tetracycline resistance.
Wild Birds as Drivers of Salmonella Braenderup and Multidrug Resistant Bacteria in Wetlands of Northern Italy.
The study identifies several AMR genes in bacterial isolates from wild aquatic birds in Northern Italy, including beta-lactamases (blaTEM, blaCMY-1, blaCMY-2, blaNDM, blaKPC), colistin resistance genes (mcr-2, mcr-3, mcr-4), tetracycline resistance genes (tetA, tetB, tetC, tetL, tetM, tetK), macrolide resistance genes (ermB, vatD, vgA, msrC), vancomycin resistance genes (vanC1, vanC2, vanM, vanG), sulfonamide resistance genes (sul1, sul2, sul3), aminoglycoside resistance genes (aac(3), aac(6')-Ib, aph(3')-Ia, armA, rmtB, rmtC, rmtF), and nitrofurantoin resistance genes (nfsA, nfsB).
A decade of genomic and phenotypic adaptation of carbapenem-resistant Acinetobacter baumannii.
The study identifies various AMR genes and mutations in carbapenem-resistant Acinetobacter baumannii isolates, including blaOXA-23, blaOXA-51-like, and several aminoglycoside resistance genes, contributing to extensive drug resistance.
Antimicrobial Resistance in Nigeria: A Comprehensive Review of Environmental, Food, and Clinical Impacts
The study identifies several AMR genes, including bla CTX-M-15, floR, and various tetracycline and sulfonamide resistance genes, highlighting the spread of multidrug-resistant bacteria in Nigeria's environment, food supply chain, and clinical settings.
Whole genome sequencing reveals virulence-mobile element linkages and phylogenetic diversity in multidrug-resistant Escherichia coli from Nigeria.
The study identified multidrug-resistant Escherichia coli isolates from Nigeria, highlighting the presence of virulence genes and mobile genetic elements, along with specific mutations in gyrA and parC that confer resistance to fluoroquinolones.
Genomic Insights of Antibiotic-Resistant Escherichia coli Isolated from Intensive Pig Farming in South Africa Using 'Farm-to-Fork' Approach.
The study identified multiple antibiotic resistance genes and mutations in E. coli isolates from intensive pig farming in South Africa, highlighting the spread of resistance across the pork production continuum.
Local Genomic Epidemiology of Acinetobacter baumannii Circulating in Hospital and Non-hospital Environments in Kano, Northwest Nigeria.
The study identifies various AMR genes in Acinetobacter baumannii isolates from hospital and non-hospital environments in Kano, Nigeria, including bla OXA-66, bla OXA-180, bla ADC-25, aadA1, aph(3')-Ia, aph(3'' )-Ib, aac(3)-Ia, aph(6)-Id, tetB, sul1, and sul2, which confer resistance to beta-lactams, aminoglycosides, tetracyclines, and sulfonamides.
Retrospective analysis of antimicrobial resistance of Salmonella spp. isolated from livestock and its environment in Thailand.
The study identified several AMR genes in Salmonella isolates from livestock and their environment in Thailand, including aadA1, aadA2, aadB, aac(6')-Ia, blaTEM, tetA, tetB, catA, catB, cmlA, sulI, and dfrA1, which confer resistance to various antibiotics such as aminoglycosides, beta-lactams, tetracyclines, chloramphenicol, sulfamethoxazole, and trimethoprim.
Acquired antibiotic resistance of Pseudomonas spp., Escherichia coli and Acinetobacter spp. in the Western Balkans and Hungary with a One Health outlook.
The study identifies various acquired antibiotic resistance genes in Pseudomonas spp., Escherichia coli, and Acinetobacter spp. in the Western Balkans and Hungary, including beta-lactamases like bla VIM-2-like, bla NDM-1, bla OXA-23, and bla OXA-66, aminoglycoside resistance genes such as aacA4, aadA2, and aphA, sulfonamide resistance gene sul1, and others. These genes confer resistance to multiple antibiotics, highlighting the complexity of antimicrobial resistance in the region.
Genomic features of three major diarrhoeagenic Escherichia coli pathotypes in India.
The study identifies a variety of acquired antimicrobial resistance (AMR) genes in diarrhoeagenic Escherichia coli (DEC) strains from India, highlighting the prevalence of resistance to multiple antibiotic classes, including aminoglycosides, beta-lactams, sulfonamides, and tetracyclines. Key AMR genes include blaTEM-105, strB, strA, mphA, sul1, sul2, addA1-pm, tetA, tetB, blaCTX-M15, blaCTX-M27, and blaDHA-1. Additionally, mutations in the quinolone resistance-determining regions (QRDRs) of gyrA and parC were found to contribute to fluoroquinolone resistance.
Genomic epidemiology reveals antibiotic resistance transfer and polyclonal dissemination of Acinetobacter baumannii in a Paraguayan hospital.
The study identifies multiple antibiotic resistance genes, including blaOXA-23, ADC-344, ADC-345, blaTEM-1, Sul1, Sul2, and TetB, in Acinetobacter baumannii isolates from a Paraguayan hospital, highlighting the presence of multidrug-resistant strains and horizontal gene transfer of resistance mechanisms.
Prevalence and antimicrobial resistance of Salmonella enterica isolated from cattle farms in Inner Mongolia.
The study identified several AMR genes in Salmonella enterica isolates from Inner Mongolia, including bla TEM-1, cmlA, tetA, tetB, tetM, aadA2, aph(3')-IIa, aacC4, aac(3)-IIa, sul1, sul3, oqxA, and oqxB, which confer resistance to beta-lactams, chloramphenicol, tetracyclines, aminoglycosides, sulfonamides, and quinolones.
Overlooked Enterobacterales as hosts of antimicrobial resistance in aquatic environments.
The study identified several AMR genes in environmental Enterobacterales isolates, including blaTEM-1, blaCTX-M, tetA, tetB, tetC, tetL, tetM, sul1, sul2, qnrS, ermB, and mefA, which conferred resistance to various antibiotics such as ampicillin, ceftazidime, cefepime, tetracycline, trimethoprim-sulfamethoxazole, ciprofloxacin, and erythromycin.
Emergence of carbapenem-resistant Acinetobacter baumannii clonal complex 2 in multiple hospitals in São Paulo state, Brazil.
The study identifies the emergence of carbapenem-resistant Acinetobacter baumannii clonal complex 2 (CC2) in multiple hospitals in São Paulo, Brazil, with resistance genes including blaOXA-23, armA, aadB, aphA1, aphA6, sul1, sul2, and tetB.
Biofilm Formation and Antibiotic Resistance Genes of Escherichia coli From Poultry Farms and Clinical Samples.
The study identified several AMR genes in E. coli isolates from poultry and clinical samples, including blaTEM, gyrA, gyrB, qnrB, qnrB4, qnrS, blaCTX-M, sul1, sul2, tetA, and tetB. These genes conferred resistance to various antibiotics such as beta-lactams, fluoroquinolones, sulfonamides, and tetracyclines. High levels of resistance were observed against tylosin, neomycin, tetracycline, ampicillin, doxycycline, ciprofloxacin, and trimethoprim/sulfamethoxazole.
Analyzing Shigella in Wuhan: Serotypes, Antimicrobial Resistance, and Public Health Implications.
The study identified multiple AMR genes and mutations in Shigella flexneri isolates from Wuhan, including blaCTX-M, blaOXA, blaTEM, dfrA1, sul2, tetB, aadA1, and qnrS, along with specific mutations in gyrA, parC, and parE that confer resistance to various antibiotics.
Molecular and phenotypic characteristics of isolated Escherichia coli from the skin, gills, and intestine of rainbow trout in retail stores of Kerman, Iran.
The study identified several AMR genes in E. coli isolates from rainbow trout, including blaTEM, qnrA, tetB, sul1, and sul2, which confer resistance to beta-lactams, fluoroquinolones, tetracyclines, and sulfonamides.
Genetic diversity, virulence genes, antimicrobial resistance, and biofilm formation of Klebsiella pneumoniae isolated from bovine mastitis milk in South Korea.
The study identified several AMR genes in K. pneumoniae isolates from bovine mastitis milk in South Korea, including blaSHV, strA, strB, sulI, sulII, tetA, tetB, tetC, floR, dfrXII, blaTEM, blaCTX-M, and blaOXA, which confer resistance to various antibiotics such as ampicillin, gentamicin, trimethoprim/sulfamethoxazole, tetracycline, chloramphenicol, and others.
Resistance, virulence and genetic diversity of Salmonella Typhimurium in South Africa (1999-2021).
The study identified several AMR genes in Salmonella Typhimurium isolates from South Africa, including beta-lactamases (bla PSE, bla CMY-2, bla TEM, bla SHV), sulfonamide resistance genes (sul1, sul2, sul3), fluoroquinolone resistance genes (qnrA, qnrB, qnrS), tetracycline resistance genes (tetA, tetB), and trimethoprim resistance genes (dfrXI, dfrXII).
Multidrug-resistant Pseudomonas aeruginosa: Pathogenesis, resistance mechanisms, and novel therapeutic strategies.
The paper discusses the multidrug resistance mechanisms of Pseudomonas aeruginosa, including beta-lactamases, aminoglycoside modifying enzymes, efflux pumps, and mutations in porin genes. It highlights the role of these mechanisms in antibiotic resistance and the challenges they pose in treating infections.
Pathogenic potential of amoxicillin-clavulanic acid resistant Klebsiella pneumoniae isolated from aquatic environment: a study of multidrug resistance and virulence.
The study identified several AMR genes in AMC-resistant K. pneumoniae isolates from aquatic environments, including bla TEM, bla SHV, bla CTX-M, bla NDM, bla OXA-48, bla CMY, qnr S, qnr B, tet A, tet B, sul 1, dfr A12, intl 1, intl 2, mrk D, ecp A, and iuc C. These genes were associated with resistance to multiple antibiotics, highlighting the complex resistance profiles of these isolates.
Prevalence and Genetic Characterization of Antimicrobial-resistant Escherichia coli from Wild Boar Meat in Japan.
The study identified antimicrobial-resistant Escherichia coli in wild boar meat in Japan, with resistance genes including blaTEM, strA, strB, aacC2, aphA1, tetA, and tetB.
Emerging threat of antimicrobial resistance determinants and plasmid replicon types acquisition by Escherichia coli of poultry and other food-producing animal origin in China: local findings with global implications.
The study identifies multiple antimicrobial resistance genes in Escherichia coli from poultry and other food-producing animals in China, highlighting the prevalence of beta-lactamases, tetracycline resistance genes, aminoglycoside modifying enzymes, quinolone resistance genes, and sulfonamide resistance genes.
Research of antimicrobial resistance and its associated genes distribution in Escherichia coli from diarrheic calves in the Ulagai region of China.
The study identified several antimicrobial resistance genes in E. coli isolates from diarrheic calves in the Ulagai region of China, including sul2, TEM-1, tetR, strB, QacH, floR, and CTXM-55, which were associated with resistance to various antibiotics.
Molecular, biofilm and motility characterization of Acinetobacter baumannii isolated from a neonatal intensive care unit at a children's hospital in South China.
The study identified multiple AMR genes in CRAB isolates from a NICU outbreak, including carbapenemases (blaOXA-23, blaOXA-66), beta-lactamases (blaADC-25, blaTEM-1D), aminoglycoside resistance genes (armA, aph(3')-Ia, aph(3'')-Ib, aph(6)-Id), macrolide resistance genes (mphE, msrE), tetracycline resistance gene (tetB), and efflux pump genes (adeABC, adeFGH, adeIJK, acrAB).
Genomic analysis of multidrug-resistant Salmonellaenterica Serovar Montevideo isolates in China.
The study identified multiple AMR genes in Chinese S. Montevideo isolates, including beta-lactamases (bla TEM−1B, bla OXA−1, bla LAP−2, bla CTX−M−55, bla CTX−M−65, bla DHA−1), quinolone resistance genes (qnrS2, qnrS1, qnrA1, qnrB6, qnrB4, qepA1), macrolide resistance genes (mphA, mphE, msrE, mphB), tetracycline resistance genes (tetA, tetD, tetB), sulfonamide resistance genes (sul1, sul2, dfrA14, dfrA12, dfrA27, sul3), and chloramphenicol resistance genes (floR, catA2, catB3).
Comparative genomics reveals avian Acinetobacter baumannii as antimicrobial resistance reservoirs and bovine strains with elevated pathogenicity.
Avian Acinetobacter baumannii strains were found to carry a significantly higher number of antimicrobial resistance genes compared to bovine and porcine strains, highlighting their potential role in the dissemination of antimicrobial resistance through animal origin foods.
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