Browse AMR Genes

Explore antimicrobial resistance genes from the literature

tetM

ribosomal protection

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to tetM

Browse AMR rules for tetM

Overview

Drug Classes: tetracycline, tigecycline
Organisms: Enterococcus faecalis
Papers: 2
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
G1058C	-	-	-	tetracycline	Reslit	Candidate
F473I	-	-	Enterococcus faecalis	tigecycline	Reslit	Candidate

Papers2

1

The Development of Third-Generation Tetracycline Antibiotics and New Perspectives.

PMID 34959366 · 2021

Mutation Information

Protein Change: G1058C
Confers Resistance To: tetracycline
Validation Method: experimental validation
Source Database: Reslit

2

Molecular basis for the emergence of a new hospital endemic tigecycline-resistant Enterococcus faecalis ST103 lineage.

PMID 30393188 · 2019

Phe473Ile substitution in tetM contributes to tigecycline resistance

Mutation Information

Protein Change: F473I
Organisms: Enterococcus faecalis
Confers Resistance To: tigecycline
Validation Method: genome comparison, mRNA abundance analysis
Source Database: Reslit