teta(64)

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tetracycline-specific efflux pump of the major facilitator superfamily

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Protein entries specific to teta(64)

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Validation StatusCandidate

Overview

Validation Method: transposon mutagenesis and complementation
Drug Classes: tetracycline, doxycycline
Organisms: Burkholderia ubonensis
Papers: 1
Databases: Reslit

Papers1

Burkholderia ubonensis High-Level Tetracycline Resistance Is Due to Efflux Pump Synergy Involving a Novel TetA(64) Resistance Determinant.

PMID 33318011 · 2021

The study identifies a novel tetracycline-specific efflux pump, TetA(64), in Burkholderia ubonensis, which contributes to high-level tetracycline and doxycycline resistance through synergy with the AmrAB-OprA efflux pump.

Gene Information

Gene Name: teta(64)
Allele: tetA(64)
Encodes: tetracycline-specific efflux pump of the major facilitator superfamily
Source Database: Reslit
Confers Resistance To: tetracyclinedoxycycline
Organisms Tested In: • Burkholderia ubonensis
Validation Method: transposon mutagenesis and complementation
Sequence Accession: MW052058

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teta(64)

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teta(64)

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