Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
tetracycline efflux pump
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| tetA(C) | Reslit | 2 | tetracycline | Escherichia coli +1 | Switzerland|United States | 2006, 2017 | PRJEB17986 | - |
| tetA (C) | Reslit | 1 | tetracycline | Escherichia coli | - | 2009 | - | - |
Reduction of acid tolerance by tetracycline in Escherichia coli expressing tetA(C) is reversed by cations.
The study shows that the tetracycline efflux pump encoded by tetA(C) reduces acid tolerance in E. coli, and this effect can be reversed by the addition of certain cations.
Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes.
The study shows that the interplay between the tetracycline resistance efflux pump TetA(C) and the ampicillin resistance gene bla TEM-1 in E. coli biofilms leads to multidrug resistance. The presence of subinhibitory concentrations of ampicillin and tetracycline enhances biofilm formation and resistance to multiple antibiotics.
The Chlamydia suis Genome Exhibits High Levels of Diversity, Plasticity, and Mobile Antibiotic Resistance: Comparative Genomics of a Recent Livestock Cohort Shows Influence of Treatment Regimes.
The study identifies the presence of the tetA(C) gene in Chlamydia suis isolates, which confers tetracycline resistance. The Tet-island carrying this gene varies in structure but is consistently found in the same genomic location.
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