Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
tetracycline efflux pump
Overview
The shared antibiotic resistome of soil bacteria and human pathogens.
The study identifies multiple antibiotic resistance genes in soil bacteria that are identical to those found in human pathogens, highlighting the exchange of resistance genes between environmental and clinical microbes.
Multidrug Resistance Salmonella Genomic Island 1 in a Morganella morganii subsp. morganii Human Clinical Isolate from France.
The study reports the first identification of Salmonella genomic island 1 (SGI1) in a multidrug-resistant clinical isolate of Morganella morganii subsp. morganii, carrying resistance genes dfrA15, floR, tetA(G), blaCARB-2, and sul1, conferring resistance to trimethoprim, chloramphenicol, tetracycline, ticarcillin, and sulfonamides, respectively.
Scarless Removal of Large Resistance Island AbaR Results in Antibiotic Susceptibility and Increased Natural Transformability in Acinetobacter baumannii.
The study shows that removing the AbaR resistance island from Acinetobacter baumannii restores antibiotic susceptibility and increases natural transformability. Several AMR genes within AbaR were identified, including aadB, aacC1, aphA1b, aacA, aadA1, strA, strB, blaVEB-1, blaOXA-10, sul1, dhfrI, dhfrX, tetA(A), tetA(G), cmlA1, cmlA5, cmlA9, catA1, arr-2, and sup.
Genomic Identification of Multidrug-Resistant Salmonella Virchow Monophasic Variant Causing Human Septic Arthritis.
The study identifies a multidrug-resistant Salmonella Virchow monophasic variant (Salmonella 6,7,14:r:-) that exhibits resistance to chloramphenicol, tetracycline, trimethoprim, sulfamethoxazole, and nalidixic acid. The resistance is conferred by the presence of cmlA9, drfA1, sul1, tetA(G), and a gyrA(S83F) mutation.
Binding of Tetracyclines to Acinetobacter baumannii TetR Involves Two Arginines as Specificity Determinants.
The study identifies that the tetA(G) gene from Acinetobacter baumannii confers resistance to various tetracyclines, and characterizes specific mutations in the AbTetR repressor that alter tetracycline binding and resistance specificity.
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