tmrB

tunicamycin resistance protein

Validation StatusConfirmed2+ DBs

Overview

Mechanism: reduced permeability to antibiotic
Validation Method: genomic analysis
Drug Classes: tigecycline
Organisms: Bacillus subtilis subsp. subtilis str. 168, Proteus mirabilis
Geographic Location: China
Papers: 1
Databases: Card DatabaseReslit

Papers1

Gene Information

Gene Name: tmrB
Allele: tmrB
Encodes: tunicamycin resistance protein
Source Database: Card Database
Mechanism: reduced permeability to antibiotic
Organisms Tested In: • Bacillus subtilis subsp. subtilis str. 168
Sequence Accession: AL009126.3
Protein Accession: CAB12108.2
Notes: ARO:3003059

Genomic characteristics of clinical multidrug-resistant Proteus isolates from a tertiary care hospital in southwest China.

PMID 36090113 · 2022

The study identifies multiple AMR genes in clinical multidrug-resistant Proteus isolates, including bla CTX-M-65, bla OXA-1, bla KPC-2, bla NDM-1, and others, highlighting the genetic diversity of mobile genetic elements carrying resistance genes.

Gene Information

Gene Name: tmrB
Allele: tmrB
Encodes: efflux pump
Source Database: Reslit
Mechanism: efflux
Confers Resistance To: tigecycline
Organisms Tested In: • Proteus mirabilis
Geographic Location: China
Validation Method: genomic analysis
Sequence Accession: CP065039|CP029118|CP017083|KP090113|MW699445|CP079626|LR697099|AP012208|JX141473|JQ010984|CP089604

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